Hotels in Santa Isabel

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Where to stay in Santa Isabel?

A thatched-roof hut on a sandy beach with palm trees and a clear blue sky.

A small, single-story wooden building with a green corrugated metal roof, a hammock strung across the front, and a wooden porch.

A small, wooden room with two single beds, a small table, and a window.

A boat on turquoise water with a beach and palm trees in the background.

1. Trips Guna Yala

Narganá

$93

$229 total

includes taxes & fees

Oct 20 - Oct 21

A tropical resort with thatched-roof huts, palm trees, and sandy ground.

A rustic thatched-roof hut with a wooden door and a small porch area.

A wooden hut with a thatched roof on a sandy beach.

A single bed with a floral pillow in a room with wooden walls and a thatched roof.

2. Cabins on paradise San Blas island

Narganá

$269

$296 total

includes taxes & fees

Oct 21 - Oct 22

A person holding a starfish in clear turquoise water with a distant island and boats in the background.

A wooden pier leading to a thatched-roof structure over a clear blue pool.

A wooden cabin with a metal roof, situated on a grassy area near a body of water, with palm trees in the background.

A wooden deck with a hammock, a pier with overwater bungalows, and boats on the water.

3. Private wood Cabins on San Blas island - private bathroom

Narganá

$131

$144 total

includes taxes & fees

Nov 1 - Nov 2

A modern house with a swimming pool, surrounded by palm trees and a clear sky.

A modern building with a stone facade, a tiled roof, and a gravel driveway.

A kitchen with wooden cabinets, a gas stove, a microwave, and a sink.

A bedroom with a large bed, a television, a nightstand, and a view of the beach.

4. Casa frente al mar - turtle cay marina

Nombre de Dios

$535

$628 total

includes taxes & fees

Nov 15 - Nov 16

An aerial view of a tropical island with thatched-roof huts and palm trees.

A wooden deck with a railing overlooking a beach with clear blue water and distant islands.

A small, green-walled bathroom with two toilets, a sink, and a shower curtain.

A wooden bed with a mosquito net, a patterned bedspread, and a small stool.

5. Private Ocean-Front Cabin with private bathroom on San Blas Island

Narganá

$188

$207 total

includes taxes & fees

Oct 21 - Oct 22

A beach with clear turquoise water, a sandy shore, and palm trees.

A wooden beach hut with a table and chairs, a window, and a view of the ocean.

A small wooden structure with a corrugated metal roof, situated on a sandy beach with palm trees in the background.

An aerial view of a coastal area with a marina, boats, and surrounding islands.

6. Cabins in Chichime Island

Narganá

$160

$176 total

includes taxes & fees

Oct 20 - Oct 21

A hammock between palm trees on a beach with clear turquoise water.

A table set for breakfast on a boat with various food items, condiments, and a view of the sea.

A compact kitchen with a stove, sink, and storage cabinets.

A modern interior with a dining area, seating, and a kitchen.

7. Cocoloco - Catamaran Lagoon 52F SAN BLAS

Narganá

$2,045

$2,250 total

includes taxes & fees

Oct 28 - Oct 29

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Learn more about Santa Isabel

While in the area, you can enjoy nearby attractions like Porvenir Museum.

See all hotels in Santa Isabel

A tropical island with a beach, clear turquoise waters, and lush greenery.

Check out reviews of Santa Isabel hotels guests love

Private Ocean-Front Cabin with private bathroom on San Blas Island

10/10 Excellent

"Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. "

Frequently asked questions

Can I book a refundable accommodation in Santa Isabel?

If you need the flexibility to change your plans to Santa Isabel, most hotels provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Santa Isabel be like during my vacation?

With an average temperature of 78°F during the coldest months, Santa Isabel is a great place to visit any time of year.

Why should I book my Santa Isabel accommodation with Hotels.com?

There are lots of reasons to book your Santa Isabel trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.