A city skyline with high-rise buildings, a calm waterfront, and a sunset sky.

4 Star Hotels in Panama City

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4 Star Hotels in Panama City

A high-rise building with a modern architectural design, featuring a grid of windows and balconies.

A modern spa area with a hot tub, seating, and a city view.

A rooftop lounge with modern seating and a panoramic city view.

A rooftop pool area with purple lounge chairs and a city skyline in the background.

1. Megapolis Hotel Panamá

San Francisco

$161

$177 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor patio with wooden tables and beige umbrellas, surrounded by lush greenery and palm trees.

A playground with multiple slides and climbing structures.

A hotel room with two beds, a nightstand with a phone, and a wall-mounted light fixture.

A white van with floral graphics and text advertising a shuttle service to an airport.

2. Riande Aeropuerto Hotel & Casino

Tocumen Airport

$108

$119 total

includes taxes & fees

Sep 27 - Sep 28

A balcony with wicker chairs and a view of the cityscape.

A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.

A hotel room with a large bed, a desk with a lamp, a chair, and a view of a cityscape through a window.

A rooftop pool area with a view of high-rise buildings in the background.

3. Ramada Plaza by Wyndham Panama Punta Pacifica

San Francisco

$104

$114 total

includes taxes & fees

Sep 26 - Sep 27

A rooftop pool with sun loungers and a city skyline in the background.

A spacious lobby with a blue sofa, multiple armchairs, and a coffee table.

A bar area with a curved counter, multiple screens, and a patterned carpet.

A long, narrow hallway with a wooden floor and light-colored walls.

4. Waymore Hotel Spa & Casino

Bella Vista

$71

$133 total

includes taxes & fees

Sep 26 - Sep 27

A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.

A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.

A modern lounge area with a wooden partition, a bar with a variety of bottles, and a seating area with chairs.

A coastal building complex with multiple structures, a prominent tower, and a beach in the foreground.

5. Courtyard by Marriott Panama Multiplaza Mall

San Francisco

$118

$130 total

includes taxes & fees

Oct 10 - Oct 11

A spacious indoor area with high ceilings, large windows, and multiple dining tables.

A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.

A spacious lobby with a tiled floor, large windows, and potted plants.

A multi-story hotel with a central courtyard, balconies, and a view of the city skyline.

6. American Trade Hotel

Casco Viejo

$179

$197 total

includes taxes & fees

Oct 1 - Oct 2

A multi-story building with balconies, arched windows, and decorative railings.

A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.

A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

A multi-level atrium with wooden staircases, seating areas, and a decorative ceiling.

7. Central Hotel Panama Casco Viejo

Casco Viejo

$171

$188 total

includes taxes & fees

Sep 29 - Sep 30

A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.

A swimming pool with a clear water surface, surrounded by a covered area with lounge chairs and a bar area.

A modern bar area with a central island, bar stools, and a television mounted on the ceiling.

A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.

8. Crowne Plaza Panama Airport by IHG

Tocumen Airport

$136

$156 total

includes taxes & fees

Oct 6 - Oct 7

A restaurant with multiple dining tables, chairs, and a central water feature.

A bar area with multiple seating options, a bar counter, and a fireplace.

A historic building with ornate stonework and a balcony with plants.

A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

9. Hotel La Compañía Casco Antiguo

Casco Viejo

$280

$308 total

includes taxes & fees

Sep 27 - Sep 28

A modern building with a glass facade, a curved structure, and a flat roof.

A modern hotel room with a large bed, a desk with a flat-screen TV, a city view, and a large painting on the wall.

A modern hotel room with a large bed, a TV, a desk, and a view of the city.

A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.

10. Decapolis Hotel Panama City

San Francisco

$111

$122 total

includes taxes & fees

Oct 10 - Oct 11

A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.

A modern bar area with wooden bar stools, a black countertop, and a display of wine bottles.

A modern hotel lobby with beige sofas, marble flooring, and a reception desk.

A dimly lit restaurant with wooden decor, tables, and chairs arranged for dining.

11. Hotel San Felipe

Casco Viejo

$145

$160 total

includes taxes & fees

Sep 27 - Sep 28

A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.

A buffet setup with various dishes and utensils.

A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.

A modern hotel lobby with a glass railing, seating area, and contemporary lighting fixtures.

12. Marriott Panama Hotel

Panama City

$169

$186 total

includes taxes & fees

Oct 10 - Oct 11

A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.

A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.

An indoor swimming pool with lounge chairs and a modern interior design.

A spacious lobby with a staircase, seating area, and a bar.

13. Las Americas Golden Tower Panama

San Francisco

$132

$145 total

includes taxes & fees

Sep 29 - Sep 30

A rooftop pool with lounge chairs and a city skyline view.

A gym with treadmills, elliptical machines, free weights, and a bench.

A hotel room with a bed, a sofa, an ottoman, a wall-mounted lamp, and a wardrobe.

A woman sitting on a bed in a hotel room with a city view.

14. Hotel Dann Carlton Marinn Place Panama Financial District

Bella Vista

$78

$113 total

includes taxes & fees

Sep 27 - Sep 28

A buffet with various food items including fruits, juices, and cheeses.

An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.

A hotel reception area with a wooden reception desk, seating area with chairs and ottomans, and a large window providing natural light.

A gym with treadmills, weight machines, and dumbbells.

15. Courtyard by Marriott Panama Metromall

San Antonio

$101

$111 total

includes taxes & fees

Oct 16 - Oct 17

A resort with a pool area, lounge chairs, and a view of a bridge at night.

A hotel room with a bed, a TV on a wooden cabinet, a nightstand with a lamp, and a view of the outdoors through a glass door.

A bar area with a counter, stools, and a seating area with tables and chairs.

A formal dining area with round tables, white tablecloths, and blue lace borders.

16. Radisson Hotel Panama Canal

Amador

$78

$86 total

includes taxes & fees

Sep 26 - Sep 27

A balcony with a view of a swimming pool, palm trees, and city buildings.

A reception area with marble reception desks and a sign indicating the reception desk.

A hotel room with a large bed, a smaller bed, a sofa, a TV mounted on the wall, and a dining area with a table and chairs.

17. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Bella Vista

$102

$112 total

includes taxes & fees

Oct 18 - Oct 19

A rooftop pool with blue lounge chairs and a city skyline view.

A modern lounge area with white furniture, glass tables, and a city view.

A modern building with a glass entrance, seating area, and a reception desk.

A modern interior with a seating area, a wine rack, and a bar.

18. Best Western Plus Panama Zen Hotel

Bella Vista

$106

$116 total

includes taxes & fees

Sep 26 - Sep 27

A grand, illuminated building with a symmetrical facade, multiple balconies, and a prominent entrance.

A kitchen with a glass-top table, a coffee machine, wine glasses, and a bottle of wine.

A restaurant interior with a large indoor tree, tables, chairs, and a display of potted plants.

A spacious bedroom with a large bed, a chandelier, a bathroom with a bathtub, and a dining area.

19. La Concordia Boutique Hotel

Casco Viejo

$202

$222 total

includes taxes & fees

Oct 9 - Oct 10

A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.

A bar area with a variety of liquor bottles, a counter, and seating with tables and chairs.

A buffet setup with various food items, including bread, pastries, and a variety of dishes in bowls.

A spacious lobby with large windows, a curved ceiling, and a seating area with a patterned rug.

20. Novotel Panama City

Bella Vista

$99

$109 total

includes taxes & fees

Oct 19 - Oct 20

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Top neighborhoods in Panama City

A coastal cityscape with a prominent church tower, a river, and distant mountains.

A statue of a man on horseback, a white building with balconies, and a well-lit plaza.

A cityscape with historic buildings, a statue, and a clear sky.

A historic building with ornate balconies and a clock tower in the background.

A statue with inscriptions, a flag, and a church with a bell tower.

Casco Viejo

Casco Viejo's cobblestone streets tell Panama's colonial story at every turn. The golden Metropolitan Cathedral and historic theaters create a living museum vibe. Rooftop bars offer spectacular bay views while museums showcase Panama's diverse heritage. Plaza hopping rewards you with hidden architectural gems and cultural performances that bring history to life. The neighborhood serves up everything from fusion cuisine in restored mansions to traditional Panamanian dishes. Boutique hotels occupy colonial buildings with charming courtyards and personalized service. Though compact, comfortable walking shoes are essential for navigating the uneven historic streets.

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A harbor with several boats docked in the foreground and a city skyline in the background.

A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.

A coastal cityscape with high-rise buildings and a curved bay.

A cityscape with modern skyscrapers, including a distinctive twisting tower.

A city street lined with palm trees and high-rise buildings.

Bella Vista

Bella Vista balances Panama City's sleek business side with upscale urban living. Gleaming skyscrapers along Avenida Balboa house financial headquarters while trendy spots on Calle Uruguay buzz with after-work crowds. Shop at MultiPlaza Pacific mall, visit Crown Casino, or simply stroll the waterfront promenade for stunning bay views. Getting around is a breeze with two metro stations and plentiful taxis. Dining options range from rooftop restaurants to international cuisine that won't disappoint. High-rise hotels with spectacular views cater to business travelers and tourists who appreciate modern comforts with a side of ocean breeze.

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A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

El Cangrejo pulses with modern energy around the iconic "El Tornillo" tower, where art meets business in Panama City's cosmopolitan heart. Korean BBQ aromas mingle with coffee scents from sidewalk cafes, while galleries showcase local talent beneath tropical sunshine. Colorful murals splash across office buildings as diverse cultures blend in this trendy district. The neighborhood serves up an eclectic fusion of Korean, Jewish, and Panamanian cuisines in stylish eateries and casual cafes. Modern boutique hotels and upscale business lodging dominate accommodation options. Getting around is a breeze with nearby Metro Line 1 stations, abundant taxis, and pleasantly walkable streets.

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A cityscape with modern high-rise buildings and a clear blue sky.

A spiraling skyscraper against a clear blue sky.

Obarrio

Obarrio dazzles with gleaming skyscrapers housing Panama City's financial powerhouses and luxury shopping. Multiplaza Pacific mall tempts with designer boutiques while the business crowd buzzes between meetings. When you're not trying your luck at local casinos, relax at a sophisticated coffeehouse or stroll the wide, clean sidewalks of Calle 50. Hotels range from international chains to boutique properties, with rates reflecting the upscale surroundings. Getting around is a breeze with excellent taxi service, frequent buses along Via España, and the Metro Line 1 connecting directly to Iglesia del Carmen station.

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A coastal cityscape with high-rise buildings and a marina.

A city skyline with tall buildings and a clear blue sky.

Punta Pacifica

Punta Pacifica's gleaming glass towers and an iconic sail-shaped skyscraper create a skyline that screams luxury with a Pacific Ocean backdrop. Stroll the waterfront promenades where swaying palms frame perfect sunset views, or duck into Multiplaza Pacific Mall to browse designer boutiques in marble-floored splendor. The neighborhood balances business and pleasure with its mix of corporate offices and upscale leisure spots. Dining here means international cuisine with ocean views at rooftop bars and hotel restaurants where reservations are smart moves. High-rise hotels and serviced apartments offer amenities like infinity pools and concierge services. Getting around is easy with abundant taxis and walkable streets, though you won't find much public transit in this polished enclave.

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Top landmarks in Panama City

A cityscape with a rainbow over buildings.

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)

If you want to give your credit card some exercise, head out to Multiplaza Pacific Mall in San Francisco. Splash some more cash at Avenida Balboa, Multicentro Panama, and Pacific Center.

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A marina with numerous boats, a bridge in the background, and lush green hills.

Amador Causeway

9.0/10 (1,902 reviews)

If you're planning a bit of sightseeing head to Amador Causeway— just one of the monuments in Amador. You can also discover the churches and cathedral in the area— your sightseeing tour starts here. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.

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A city skyline with tall buildings along a waterfront.

Cinta Costera

9.2/10 (3,823 reviews)

Cinta Costera is worth a pic or two when discovering Calidonia.

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A nighttime cityscape with illuminated skyscrapers and a river reflecting the lights.

Avenida Balboa

8.8/10 (3,608 reviews)

If you want to give your credit card some exercise, head out to Avenida Balboa in Calidonia. Splash some more cash at Multicentro Panama, Uruguay Street, and Multiplaza Pacific Mall.

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Albrook Shopping Mall

8.6/10 (4,561 reviews)

Don't visit Ancon without stopping off at Albrook Shopping Mall, a top spot for shopaholics. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.

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Via Espana

8.4/10 (2,902 reviews)

If you want to give your credit card some exercise, head out to Via Espana in Bella Vista. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. Splash some more cash at Uruguay Street, Multicentro Panama, and Avenida Balboa.

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Fuerte Amador Resort & Marina

9.4/10 (169 reviews)

You can stroll along Fuerte Amador Resort & Marina for relaxing water views when you're in Amador. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. If you carry on walking you'll get to Panama Cruise Terminal for some more water views.

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El Dorado Mall

8.2/10 (1,337 reviews)

If you want to give your credit card some exercise, head out to El Dorado Mall in Bethania. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.

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