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Hotels in San Luis Rio Colorado

November 2026
December 2026

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This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Where to stay in San Luis Rio Colorado?

A modern building with a fountain, palm trees, and a clear blue sky.
A table set for a formal event with clear glassware, a floral centerpiece, and a decorative tree with lights.
A modern restaurant interior with multiple dining tables, chairs, and hanging plants.
An outdoor pool area with a covered seating area, lounge chairs, and a small water feature.

1. Hotel Mirra San Luis

Hotel Mirra San Luis
San Luis Rio Colorado
$110
$123 total
includes taxes & fees
Nov 8 - Nov 9
Hotel Mirra San Luis
A spacious indoor area with a wooden floor, a staircase, and a seating area.
A modern coffee station with a glass wall, a TV mounted on the wall, and a fire extinguisher on the right.
A modern hotel with a prominent sign, large windows, and a paved entrance area.
A reception area with a modern design, featuring a reception desk, seating area, and a large potted plant.

2. 653 Hotel

653 Hotel
San Luis Rio Colorado
$68
$81 total
includes taxes & fees
Oct 20 - Oct 21
653 Hotel
A bar with various drinks and bottles.
A hotel room with a large bed, a bedside table with a phone, and a wall-mounted light fixture.
A hotel dining area with multiple tables and chairs, a green wall with a clock, and a 'SAN ANGEL' sign.
A modern lounge area with sofas, tables, and a seating arrangement.

3. Hotel San Angel & Spa

Hotel San Angel & Spa
San Luis Rio Colorado
$119
$132 total
includes taxes & fees
Oct 20 - Oct 21
Hotel San Angel & Spa
A bedroom with a large bed, bedside tables with lamps, a dresser, a potted plant, and a radiator.
A reception area with a wooden wall, a white reception desk, and a sofa with a red cushion.
A bar area with a wooden counter and stools, large windows, and a view of buildings and hills.
A rectangular swimming pool with a wooden deck surrounding it.

4. California Comfort and Suites

California Comfort and Suites
Los Algodones
$53
$65 total
includes taxes & fees
Oct 23 - Oct 24
California Comfort and Suites
A view from a balcony with a metal grid door, a clear blue sky, and a parking lot with vehicles.
A bed with a teal quilted bedspread and two pillows, a wall-mounted lamp, and a wooden headboard with a mosaic tile accent.
A modern living room with a gray sofa, a flat-screen TV, and a colorful abstract painting.
A kitchen with a coffee maker, two coffee mugs, and a packet of coffee pods on the counter.

5. Hotel Santa Cruz Residencial

Hotel Santa Cruz Residencial
San Luis Rio Colorado
Hotel Santa Cruz Residencial
A modern kitchen with a glass dining table, dark cabinetry, and a microwave.
A bedroom with a bed, a flat-screen TV, a small table with a vase, and a door.
A modern bathroom with a shower, toilet, and sink area.
A dark wooden wardrobe with multiple drawers and a vase with flowers on a wooden table.

6. Hotel y Suites Panda

Hotel y Suites Panda
San Luis Río Colorado
Hotel y Suites Panda
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Go beyond your typical stay in San Luis Rio Colorado

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Pet friendly
Pet friendly
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Pool
Pool
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Spa
Spa
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Family friendly
Family friendly
Our prices for hotels in San Luis Rio Colorado are cheapest in December

Price trends for hotels in San Luis Rio Colorado

Pricing is based on two traveler single night rates
View properties in October

October

High 32°C / low 20°C. Sunny most days.
32°
20°
26°
13°
20°
9°
21°
10°
23°
11°
27°
13°
31°
16°
34°
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Monthly weather averages (˚C)

Top neighborhoods in San Luis Rio Colorado

Top landmarks in San Luis Rio Colorado

Forest of the City

7.8/10 (67 reviews)
Forest of the City is 1.1 mi (1.8 km) from central San Luis Rio Colorado, why not stop by during your stay. Want to stretch your legs some more? Head to Juan Antonio Ramirez Medrano Sports Complex, located nearby.
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Garita Entrance to Mexico

8.0/10 (408 reviews)
You might want to get your camera out and head to Garita Entrance to Mexico— just one of the landmarks located 2.4 mi (3.8 km) from central San Luis Rio Colorado.
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Juan Antonio Ramirez Medrano Sports Complex

7.6/10 (47 reviews)
Juan Antonio Ramirez Medrano Sports Complex is 2.6 mi (4.2 km) from central San Luis Rio Colorado, why not stop by during your stay. Want to stretch your legs some more? Head to Forest of the City, located nearby.
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Learn more about San Luis Rio Colorado

San Luis Rio Colorado is well-known for its attractions such as Garita Entrance to Mexico and Colorado River.

See all hotels in San Luis Rio Colorado
Two white domed towers with crosses, surrounded by palm trees and greenery.

Frequently Asked Questions

What accommodations do travelers like in San Luis Rio Colorado?

Guests like Hotel Mirra San Luis, 653 Hotel and Hotel San Angel & Spa.

Can I book a refundable hotel in San Luis Rio Colorado?

If you're looking for the flexibility to change your plans to San Luis Rio Colorado, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where should I stay in San Luis Rio Colorado if I'm looking for an affordable accommodation?

A few inexpensive options worth considering are Hotel Angeles, Hotel y Suites Panda and HOTEL MONTECARLO.

Where can I stay in San Luis Rio Colorado if I want a vacation rental instead of a hotel?

If you want to find a good alternative to a hotel, browse our selection of 5 vacation homes.

What will the weather in San Luis Rio Colorado be like during my visit?

July and August are typically the warmest months in San Luis Rio Colorado when the average temp is 92°F. December and January are the coldest months when the average temperature is 61°F. September and August are the months with the most rain.

Why should I book my San Luis Rio Colorado accommodation with Hotels.com?

There are lots of reasons to book your San Luis Rio Colorado trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.