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Hotels in Santiago

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Check prices for these dates

Tonight
Dec 27 - Dec 28
Tomorrow
Dec 28 - Dec 29
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

Where to stay in Santiago?

Exterior
Amet Nature Retreat
Amet Nature Retreat
4.5 star property
10.0 out of 10, Exceptional, (5)
The price is $382
$497 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Amet Nature Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Budget hotels in Santiago and vicinity

Outdoor pool
Cactus Inn Los Cabos

Cactus Inn Los Cabos

Cactus Inn Los Cabos
3.0 star property
San José del Cabo
8.4 out of 10, Very Good, (291)
The price is $72
$91 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Cactus Inn Los Cabos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top landmarks in Santiago

Tropic of Cancer Monument

4.4/5 (18 reviews)
If seeing the sights is on your list of things to do, head to Tropic of Cancer Monument— just one of the landmarks located 2.5 mi (4.1 km) from central Santiago.
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Cascada Sol de Mayo Trailhead

Cascada Sol de Mayo Trailhead is 4.7 mi (7.6 km) from central Santiago, why not stop by during your stay.
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Learn more about Santiago

Santiago is well-known for its attractions such as Tropic of Cancer Monument and Sierra La Laguna Biosphere Reserve.

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Santiago showing a church or cathedral

Check out reviews of Santiago hotels guests love

Cactus Inn Los Cabos

Cactus Inn Los Cabos

10/10 Excellent
"Super clean! Helpful and kind staff. Comfortable beds. Great water pressure in shower. "
Angie 1-night trip
Posted 4 days ago
Cactus Inn Los Cabos

Frequently asked questions

What accommodations do travelers recommend in Santiago?
Guests like Amet Nature Retreat.
Can I book a refundable accommodation in Santiago?
If you need the flexibility to change your travel plans to Santiago, most hotels offer refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
What will the weather in Santiago be like during my trip?
With an average temperature of 70°F during the coldest months, Santiago is a great place to visit any time of year.
Why should I book my Santiago accommodation with Hotels.com?
There are lots of reasons to book your Santiago trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.