Hotels in Santiago Este

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Where to stay in Santiago Este?

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.

A spacious lobby with modern seating, a central coffee table, and decorative hanging lights.

A modern hotel with a prominent entrance, outdoor seating area, and a handicap-accessible parking space.

A restaurant with booths and tables, wooden paneling, and green plants.

1. Hotel Mykonos Panama

Nuevo Santiago

$90

$99 total

includes taxes & fees

Oct 15 - Oct 16

A pool surrounded by palm trees and a tiled roof structure.

A tree in a stone planter in a well-lit indoor space with a stone wall and a door in the background.

A spacious room with a high ceiling, a large window, and a wooden door leading to another area. There are several potted plants and a small table with a vase.

A building with a curved facade, a balcony with metal railings, and a door with a sign.

2. Hotel Gran David

Santiago

$73

$80 total

includes taxes & fees

Oct 15 - Oct 16

A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.

A lobby with a reception desk, two armchairs, a sofa, and a table with a lamp.

A hotel room with two single beds, a desk with a chair, a television, and a door.

A hotel room with a dark wooden desk, two cushioned chairs, a large mirror, and two table lamps.

3. Hotel Plaza Los Tucanes

Nuevo Santiago

$52

$57 total

includes taxes & fees

Oct 15 - Oct 16

A beach with a wide sandy shore and gentle waves.

A table set with a variety of food items, including pastries, fruits, and nuts, arranged on a table with a decorative centerpiece.

A bedroom with a bed, a chair, a mirror, and an air conditioning unit.

A building with a thatched roof, a signboard with text, and a parked car.

4. olivias village room

Capellania

$41

$148 total

includes taxes & fees

Oct 15 - Oct 16

A swimming pool with a water slide, surrounded by palm trees and lounge chairs.

A modern bedroom with a large bed, a small table, and a chair. There is a window with curtains and a lamp on the wall.

A spacious dining area with high ceilings, large windows, and natural light. Tables are set with chairs and centerpieces.

A hammock suspended between two white walls in a room with a balcony.

5. HOTEL VISTA LAGO

La Pena

$77

$84 total

includes taxes & fees

Oct 15 - Oct 16

View all properties

Check out reviews of Santiago Este hotels guests love

Hotel Mykonos Panama

8/10 Good

"Deben programar realizar limpiezas profundas en las habitaciones. El servicio por parte del staff, fue bueno. Sugiero variar el desayuno de manera intercalada (por días). Esto, para no repetir lo mismo."

HOTEL VISTA LAGO

10/10 Excellent

"Todo perfecto"

Hotel Plaza Los Tucanes

10/10 Excellent

"Excelente"

Hotel Galería

10/10 Excellent

"Hay un restaurante en el hotel con desayuno y comida económica y muy sabrosa. La ubicación del hotel es muy céntrica. Es seguro. Tiene centro comercial al lado. Parqueo de carro seguro. Es perfecto para una visita a Santiago."

Frequently asked questions

Can I book refundable accommodations in Santiago Este?

If you want the flexibility to change your plans to Santiago Este, most properties offer refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Santiago Este be like during my trip?

With an average temperature of 77°F during the coldest months, Santiago Este is a great place to visit any time of year.

Why should I book my Santiago Este accommodation with Hotels.com?

There are plenty of reasons to book your Santiago Este travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.