An ancient amphitheater with stone ruins and a grassy field.

4 Star Hotels in Syracuse

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

4 Star Hotels in Syracuse

A woman holding a wine glass on a balcony overlooking a street with historic buildings and a clock tower.

A building with three balconies, a central entrance with an archway, and a sign indicating it is a small luxury hotel.

A grand lobby with arched ceilings, marble columns, a chandelier, and a reception desk.

A bar with a stone ceiling, a marble countertop, and shelves stocked with liquor bottles.

1. Palazzo Artemide - VRetreats, SLH Collection

Ortigia

$324

$368 total

includes taxes & fees

Oct 25 - Oct 26

A historic building with a central entrance, multiple balconies, and a large potted plant in front.

An interior view of a restaurant with stone arches, wooden beams, and tables set for dining.

An interior corridor with an arched stone doorway, a staircase, and a table with a vase of flowers.

A spacious living area with a large mirror, a chandelier, and a fireplace. There are multiple seating options including a sofa and chairs.

2. Algila' Ortigia Charme Hotel

Ortigia

A historic building with ornate balconies, a grand entrance, and flags of the European Union and Italy.

A grand staircase with ornate metal railings and red carpeted steps leading to a balcony area with arched doorways and a checkered floor.

A spacious living room with a large sofa, two armchairs, a dining area with a table and chairs, and a kitchen in the background.

A buffet with various food items and condiments.

3. Grande Albergo Alfeo

Santa Lucia

$119

$135 total

includes taxes & fees

Oct 17 - Oct 18

An outdoor swimming pool with a wooden deck, surrounded by white umbrellas and lounge chairs.

A reception desk with a framed picture on the wall, a potted plant, and a sign above the desk.

A hotel room with a bed, a TV mounted on the wall, and a window with curtains.

A spacious restaurant with high wooden ceilings and large windows.

4. Mercure Siracusa Prometeo

Neapolis

$108

$134 total

includes taxes & fees

Oct 25 - Oct 26

A riverside walkway with people walking and sitting, overlooking a body of water.

A stone staircase with a large urn on the landing, leading to a balcony with a metal railing overlooking the sea.

A buffet with various food items, including pastries, fruits, and beverages.

A view from an open window overlooking a body of water with a distant shoreline.

5. Charme Hotel Henry's House

Ortigia

$319

$363 total

includes taxes & fees

Oct 2 - Oct 3

A coastal terrace with wicker furniture, striped umbrellas, and a rocky backdrop.

A swimming pool with lounge chairs and umbrellas, surrounded by buildings with a staircase and a view of the city skyline.

A historic building with multiple balconies and a courtyard with palm trees.

A grand lobby with a central red seating area, a staircase, and a high ceiling with skylights.

6. Grand Hotel Villa Politi

Grottasanta

$125

$142 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, a chair, a small table, and a chandelier.

A dining area with a wooden table and chairs, a potted plant, and a tiled floor with a geometric pattern.

A modern living room with a sofa, two side tables, a chandelier, and a painting on the wall.

A modern staircase with a wooden finish, a black vase on the landing, and a lamp on the right.

7. Hotel Palazzo Cavalieri

Santa Lucia

$99

$112 total

includes taxes & fees

Sep 28 - Sep 29

A bakery display with various baked goods and a sign indicating apple and jam cake.

A hallway with a stone wall, a wooden door, and a purple-lit wall.

A spa area with a reflective pool, a candlelit candelabra, and a cave-like wall.

8. UNA Hotels One Siracusa Wellness & SPA

Grottasanta

$135

$154 total

includes taxes & fees

Oct 25 - Oct 26

A poolside setting with a person relaxing, a table with a drink and fruit, and a view of the pool and chairs in the background.

A buffet with various food items, including pastries and a meat display, in a well-lit room with a neutral color scheme.

A multi-story hotel with a covered entrance, a well-maintained lawn, and a classic architectural style.

A courtyard with tables set up for an event, surrounded by buildings with large windows and a well-lit exterior.

9. Hotel Parco delle Fontane

Tiche

$147

$167 total

includes taxes & fees

Oct 4 - Oct 5

A stone pathway leading to a sunset view, flanked by lanterns and greenery.

A cozy living room with a white sofa, a wooden coffee table with newspapers, and a bookshelf filled with books.

A modern, compact hotel room with a kitchenette, a small dining area, and a bed with a striped pillow.

An aerial view of a resort with a large, uniquely shaped swimming pool surrounded by lounge areas and palm trees.

10. Borgo Pantano

Syracuse

$183

$213 total

includes taxes & fees

Sep 29 - Sep 30

A poolside breakfast setup with a newspaper, fruit bowl, juice, and coffee.

A terrace with outdoor seating, a table with food and drinks, and potted plants.

A spacious living area with a modern design, featuring a sofa set, a coffee table, and a bookshelf.

The exterior of Albatros Hotel with a modern design, featuring a prominent sign, a well-lit entrance, and landscaped surroundings.

11. Albatros Hotel

Syracuse

$85

$97 total

includes taxes & fees

Oct 27 - Oct 28

A spacious patio area with a view of the city skyline, featuring modern furniture and potted plants.

A hotel entrance with a metal archway, double doors, and two potted plants.

A modern hotel room with a large bed, a white armchair, and a view of the outdoors through a sliding glass door.

An indoor swimming pool with blue and red lighting, surrounded by walls and a glass window.

12. Hotel Centrale

Syracuse

$129

$147 total

includes taxes & fees

Oct 8 - Oct 9

A swimming pool with a tiled deck, a covered seating area with tables and chairs, and a building with a green roof in the background.

A breakfast setup with a table, chairs, and a basket of bread.

A two-story building with a flat roof, a balcony on the second floor, and a paved driveway leading to the entrance.

An outdoor dining area with round tables and chairs, a pool, and a view of a building in the background.

13. Villa Fanusa

Syracuse

$95

$108 total

includes taxes & fees

Oct 1 - Oct 2

A clear view of a beach with rocky formations in the water.

A table set with a plate of food, a glass of orange juice, a glass of red drink, a white vase, and a cup.

A garden pathway leading to a sign that reads "Rooms Beach."

A table set with various foods and drinks, including a bottle of champagne, plates of appetizers, and glasses of water and juice, by a poolside.

14. Hotel Villamare

Syracuse

$157

$179 total

includes taxes & fees

Oct 3 - Oct 4

A clear blue pool with lounge chairs and umbrellas, surrounded by palm trees and a covered seating area.

A resort patio with palm trees, outdoor seating, and a pool area.

A modern hotel room with a bed, a desk, a chair, a television, and a view of the outdoors.

A dining area with white tables and wicker chairs, stone arches, and a rustic wooden ceiling.

15. Life Hotels Kalaonda Resort

Syracuse

$109

$124 total

includes taxes & fees

Sep 29 - Sep 30

A swimming pool with lounge chairs and umbrellas, surrounded by buildings with arched windows and palm trees.

A dining area with multiple tables and chairs, a variety of wine bottles on display, and a large window providing natural light.

A modern reception area with a black reception desk, blue and yellow chairs, and a large wall clock.

A hotel with a courtyard featuring outdoor seating and umbrellas, surrounded by palm trees and a well-maintained lawn.

16. Hotel Relax

Epipoli

$161

$183 total

includes taxes & fees

Sep 28 - Sep 29

A poolside area with lounge chairs, a rocky structure with a fishing net, and a small lighthouse model.

A spacious outdoor area with a sandy floor, a covered seating area, and a building with multiple doors and windows.

A modern bedroom with a unique geometric light design on the headboard, a neatly made bed, and a bedside table with a small plant.

A spacious dining area with high ceilings and arched doorways, featuring white furniture and a modern design.

17. Addauro Resort

Syracuse

$84

$95 total

includes taxes & fees

Oct 5 - Oct 6

A hotel entrance with a name sign, a potted plant, and a staircase.

A hotel room with a bed, a desk with a laptop, a chair, a sofa, and a painting on the wall.

A hotel room with a bed, a desk, a chair, a dining table, and a painting on the wall.

A modern bar area with a central counter, bar stools, and a coffee machine.

18. Hotel Panorama

Neapolis

$108

$123 total

includes taxes & fees

Oct 5 - Oct 6

A swimming pool with lounge chairs and umbrellas, surrounded by palm trees.

A bedroom with a bed, a desk, a chair, and a TV mounted on the wall.

A rooftop terrace with a pool, surrounded by greenery and a mountainous backdrop.

A nighttime outdoor area with trees illuminated by green lights, a paved walkway, and a stone wall.

19. Casal Sikelio

Syracuse

$127

$144 total

includes taxes & fees

Oct 8 - Oct 9

A swimming pool with clear blue water, surrounded by tropical plants and a stone wall.

A blue building with a stone archway, a tiled patio, and a staircase leading to an upper level.

An archway leading to a courtyard with a stone wall and a blue building in the background.

A covered balcony with wicker furniture and a tiled floor.

20. Borgo Marino Plemmirio

Syracuse

$133

$152 total

includes taxes & fees

Oct 5 - Oct 6

See more properties

Top neighborhoods in Syracuse

A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

A historical site with ancient ruins, including a prominent column and stone structures, set against a backdrop of traditional buildings and a busy street with palm trees.

Ancient ruins, a sign reading "Tempio di Apollo," and a man observing the site.

A historic building with ornate architecture, a fountain, and potted plants in a plaza.

A grand historical building with ornate architecture and statues.

Ortigia

Ortigia's ancient limestone streets tell 2,700 years of Mediterranean stories through every weathered stone. Greek temple ruins stand beside a stunning Baroque cathedral, while the 13th-century Castello Maniace guards this tiny island's tip. The mystical Fonte Aretusa freshwater spring creates a papyrus grove right beside the crystal-clear Ionian Sea. Waterfront trattorias serve fresh seafood and Sicilian classics while you watch fishing boats bobbing at sunset. The compact 1km island is best explored on foot through narrow medieval lanes. Historic palazzos converted to boutique hotels offer authentic stays with sea views from wrought-iron balconies.

See properties

Ancient ruins with a large amphitheater surrounded by trees.

An ancient amphitheater surrounded by trees and a clear blue sky.

A cobblestone courtyard with arches and a staircase leading to a building entrance.

Ancient ruins with stone steps and walls, surrounded by trees.

A large, modern church interior with a circular ceiling design and rows of wooden pews.

Neapolis

Step back in time at Syracuse's Neapolis, where ancient Greek and Roman civilizations come alive through remarkable ruins. The Greek Theater carved into limestone hills offers stunning harbor views, while the Roman Amphitheater reveals gladiatorial heritage. Don't miss the Ear of Dionysius cave where whispers magically amplify, or the Paradise Quarry gardens blooming with Mediterranean flora. Getting around requires walking on uneven ancient paths, with limited bus service connecting to Syracuse center. Pack a lunch or visit the small café near the entrance since dining options are minimal. The archaeological park closes at sunset, so plan your visit during daylight hours to fully experience this extraordinary outdoor museum.

See properties

A waterfront with a crowd, buildings, and a sunset.

A modern building with a conical roof and a central spire.

A large, circular building with a dome and a cross on top, featuring tall columns and large windows.

A modern building with a unique triangular roof and a central spire.

A blue building with arched windows and doors, potted plants, and a sign that reads "Barca de la".

Santa Lucia

Santa Lucia delivers an epic history lesson with every step through its honey-colored streets. The ancient neighborhood showcases Greek ruins, the legendary Tomb of Archimedes, and the stunning Church of Santa Lucia alla Badia with its soaring dome. Colorful fishing boats bob in Porto Piccolo while the Ionian Sea provides a sparkling backdrop to centuries of Mediterranean heritage. Traditional Sicilian trattorias serve fresh seafood along the waterfront promenade. Stone-walled boutique guesthouses and converted palazzo B&Bs make perfect bases for exploring this walkable historic quarter. The limited public buses mean you'll mostly discover Santa Lucia's treasures on foot, which is exactly how this ancient place should be experienced.

See properties

A natural rock arch over a body of water with people paddling in kayaks.

A coastal cityscape with modern buildings, palm trees, and a rocky cliff.

Grottasanta

The Grottasanta neighborhood offers attractions such as Pista Ciclabile Siracusa and Ionian Sea.

See properties

Tiche

Tiche's ancient Greek quarter lets you walk right through history with every step. The Greek Theater carved into limestone hosts summer performances under starlit skies, while the Temple of Apollo frames perfect Mediterranean sunsets. Explore the Archaeological Park of Neapolis with its mysterious Ear of Dionysius cave, known for its perfect acoustics and surrounded by olive groves. Traditional tavernas serve fresh seafood and arancini in family-run establishments with prices that won't break the bank. Historic guesthouses in converted ancient buildings offer authentic stays with Sicilian breakfasts included. Walking remains the primary way to get around, though public buses connect to central Syracuse when your feet need a rest.

See properties

Top landmarks in Syracuse

A coastal cityscape with buildings along the waterfront, a clear blue sky, and a calm sea.

Lungomare di Ortigia

9.4/10 (654 reviews)

Ortigia is home to Lungomare di Ortigia, so why not stop by during your stay in Syracuse.

See properties

An ancient stone structure with arches and columns, adjacent to a modern building with a dome and windows.

Temple of Apollo

8.8/10 (692 reviews)

If you're planning a bit of sightseeing head to Temple of Apollo— just one of the monuments in Ortigia. You can also discover the museums and cathedral in the area— your sightseeing tour starts here.

See properties

Fontane Bianche Beach

8.0/10 (189 reviews)

When the beach is calling your name, you might want to head down to Fontane Bianche Beach, located 8.5 mi (13.7 km) from central Syracuse. Enjoy the sunset by the shore at Gallina Beach, Ognina Beach, and Arenella Beach.

See properties

Greek Theatre of Syracuse

9.2/10 (694 reviews)

If you're planning a bit of sightseeing head to Greek Theatre of Syracuse— just one of the monuments in Neapolis. You could also start your cultural experience by heading over to the cathedral in the area.

See properties

Piazza del Duomo

9.6/10 (551 reviews)

Piazza del Duomo is worth passing through for a few pics when in Ortigia. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.

See properties

Archaeological Park of Neapolis

9.0/10 (485 reviews)

If you're planning a bit of sightseeing head to Archaeological Park of Neapolis— just one of the monuments in Neapolis. You could also start your cultural experience by heading over to the cathedral in the area.

See properties

Cathedral of Syracuse

9.4/10 (813 reviews)

If you're planning a bit of sightseeing head to Cathedral of Syracuse— just one of the monuments in Ortigia. You can also discover the cathedral and museums in the area— your sightseeing tour starts here.

See properties

Pista Ciclabile Siracusa

10.0/10 (4 reviews)

Travelers who enjoy the great outdoors might want to go to Pista Ciclabile Siracusa, located 1 mi (1.6 km) from central Syracuse.

See properties