Hotels in Santa Cruz de la Sierra

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Check prices for these dates

Tonight
Sep 17 - Sep 18
Tomorrow
Sep 18 - Sep 19
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Where to stay in Santa Cruz de la Sierra?

1. Hospedium Hotel Soterraña

Hospedium Hotel Soterraña
Madronera
$71
$79 total
includes taxes & fees
Sep 30 - Oct 1
Hospedium Hotel Soterraña

2. Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta
Trujillo
$78
$85 total
includes taxes & fees
Sep 23 - Sep 24
Eurostars Palacio Santa Marta

3. Finca El Azahar

Finca El Azahar
Trujillo
$159
$174 total
includes taxes & fees
Oct 1 - Oct 2
Finca El Azahar

4. Parador de Trujillo

Parador de Trujillo
Trujillo
$84
$92 total
includes taxes & fees
Sep 17 - Sep 18
Parador de Trujillo

5. Hostal Hueso

Hostal Hueso
Trujillo
$68
$75 total
includes taxes & fees
Sep 24 - Sep 25
Hostal Hueso

6. Hotel Izan Trujillo

Hotel Izan Trujillo
Trujillo
$95
$104 total
includes taxes & fees
Sep 17 - Sep 18
Hotel Izan Trujillo

7. Plaza Sandra

Plaza Sandra
Trujillo
$65
$72 total
includes taxes & fees
Oct 4 - Oct 5
Plaza Sandra

8. Finca la Desa

Finca la Desa
Miajadas
$76
$83 total
includes taxes & fees
Sep 17 - Sep 18
Finca la Desa

9. Hostal León

Hostal León
Trujillo
$58
$63 total
includes taxes & fees
Sep 20 - Sep 21
Hostal León

10. Alojamientos Plaza Mayor

Alojamientos Plaza Mayor
Trujillo
$39
$43 total
includes taxes & fees
Sep 20 - Sep 21
Alojamientos Plaza Mayor

11. Hospedium Hotel Triana

Hospedium Hotel Triana
Miajadas
$88
$97 total
includes taxes & fees
Sep 20 - Sep 21
Hospedium Hotel Triana

12. Hostal Ruralis Altozano

Hostal Ruralis Altozano
Montánchez
$47
$51 total
includes taxes & fees
Sep 20 - Sep 21
Hostal Ruralis Altozano
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Learn more about Santa Cruz de la Sierra

The region around Santa Cruz de la Sierra is home to attractions such as Palacio de la Conquista and Plaza Mayor.

See all hotels in Santa Cruz de la Sierra
A large brick church with two bell towers and palm trees in front.

Check out reviews of Santa Cruz de la Sierra hotels guests love

Hotel Izan Trujillo

Hotel Izan Trujillo

10/10 Excellent
"Nice hotel with a secure room for cycles for those on tour like me. Nice rooms and good facilities. Restaurant is good but also great places to eat on the Plaza."
Mark 1-night trip
Posted 3 weeks ago
Hotel Izan Trujillo
Parador de Trujillo

Parador de Trujillo

10/10 Excellent
"We had half board abd the meal was fantastic. I had the selection of meats to start and my wife had a sort of tomato mousse. The olive oil was out of this world and my main course fillet was one of the best that I have ever had. We have been trying to find a reason to travel that way again and wish we had booked for 2 nights or more. It’s a lovely little town, with a beautiful square. A great place as a base to visit Caceres or Guadalupe. We will definitely return!"
Gary 1-night trip
Posted 1 month ago
Parador de Trujillo
Plaza Sandra

Plaza Sandra

10/10 Excellent
"Era un lugar limpio y acogedor, y había muchos sitios a los que se podía ir andando. El personal fue muy atento. Aparcar fue todo un reto, sobre todo cerca del mercado semanal. Pasamos una estancia muy agradable."
Alexandra 3-night trip
Posted 3 months ago
Plaza Sandra
Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta

10/10 Excellent
"We had a wonderful stay at Eurostars Palacio Santa Marta. The hotel is set inside a beautifully restored historic building just steps from Plaza Mayor, making it perfect for exploring Trujillo on foot. Our room was spacious, comfortable, and very quiet. Alba was warm, welcoming, and made everything easy. Overall, an excellent stay in a charming location — we’d happily return."
Ismael 1-night trip
Posted 4 months ago
Eurostars Palacio Santa Marta

Frequently asked questions

What hotels do travelers recommend in Santa Cruz de la Sierra?
Can I book refundable hotels in Santa Cruz de la Sierra?
If you need the flexibility to change your plans to Santa Cruz de la Sierra, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa Cruz de la Sierra be like during my trip?
July and August are typically the warmest months in Santa Cruz de la Sierra when the average temp is 77°F. January and February are the coldest months when the average temperature is 47°F. October and December are the months with the most rain.
Why should I book my Santa Cruz de la Sierra hotel through Hotels.com?
There are lots of reasons to book your Santa Cruz de la Sierra trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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