A beach with a wooden pier extending into the ocean, palm trees, and a sunset sky.

Hotels in Saint James City

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Where to stay in Saint James City?

A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.

A modern kitchen with grey cabinets, a stainless steel refrigerator, a microwave, and a sink. There is a painting of a flamingo on the wall.

A bedroom with a large bed, a desk, and a chair. There is a sliding barn door and a painting of a beach on the wall.

A resort with a pool, thatched umbrellas, and palm trees.

1. Off the Charts Inn & Out Island Resort

Saint James City

$135

$184 total

includes taxes & fees

Oct 5 - Oct 6

A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

A swimming pool area with lounge chairs, a small building, and a basketball court surrounded by palm trees and greenery.

A modern hotel room with a large bed, two armchairs, a small side table with a lamp, and a large window with blinds.

A hotel room with two beds, a large mirror, and a view of the outdoors.

2. Residence Inn by Marriott Fort Myers Sanibel

Fort Myers

$94

$105 total

includes taxes & fees

Oct 5 - Oct 6

A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

A modern lobby with a fireplace, seating area, and artwork.

A reception area with a beach view mural, a staircase, and a reception desk.

A spacious indoor dining area with high ceilings, large windows, and modern orange chairs and white tables.

3. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Fort Myers

$80

$89 total

includes taxes & fees

Oct 8 - Oct 9

An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

A modern reception desk with a digital display, a cash register, and a customer service counter.

A Holiday Inn Express & Suites building with a parking lot, a covered entrance, and a landscaped area with flowers.

A modern indoor space with a large table, chairs, and a television.

4. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Fort Myers Beach

$84

$94 total

includes taxes & fees

Oct 5 - Oct 6

A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and artwork on the walls.

A swimming pool with lounge chairs and palm trees, surrounded by a building with a red roof and multiple windows.

A reception desk with a wooden panel design, a welcome sign for 'Sunshine State', and a motivational rug on the floor.

5. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Fort Myers Beach

$77

$86 total

includes taxes & fees

Oct 8 - Oct 9

A balcony with a table and chairs, large windows, and a view of the sea.

A spacious living area with a high ceiling, a ceiling fan, a pool table, and a view of the outdoors.

An outdoor seating area with round tables and pink cushions, palm trees, and string lights against a twilight sky.

6. The Westin Cape Coral Resort At Marina Village

Pelican

$146

$208 total

includes taxes & fees

Oct 25 - Oct 26

A beach with a variety of seashells and pebbles.

A hotel room with a bed, a view of the beach, and a window with curtains.

A landscaped area with palm trees and a view of the ocean.

A hammock between palm trees with a view of the ocean.

7. Sanibel Island Beach Resort

Mid Island

$179

$227 total

includes taxes & fees

Oct 4 - Oct 5

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

A room with a large aquarium, a dining table with chairs, a refrigerator, and a wall-mounted TV displaying a resort advertisement.

A swimming pool with a thatched roof overhead, surrounded by lounge chairs and a covered patio area.

A marina with rows of blue Adirondack chairs under turquoise umbrellas, wooden docks, and boats.

8. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Siesta Isle

$92

$102 total

includes taxes & fees

Oct 4 - Oct 5

A boat-shaped deck chair with cushions, positioned on a wooden deck with a white fence.

A kitchen with white cabinets, a microwave, a sink, and a green refrigerator.

9. The Anchor Inn

Mid Island

$142

$174 total

includes taxes & fees

Oct 8 - Oct 9

A beach with a view of the ocean and a sunset.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, and a dining area with white chairs and a table.

A multi-story hotel with a central entrance, balconies, and palm trees.

A modern living room with a sofa, chairs, and a dining table. There is a kitchen area with cabinets and appliances.

10. Island Inn

West End

$202

$225 total

includes taxes & fees

Oct 5 - Oct 6

A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

A spacious lobby with a staircase, large windows, and a chandelier.

A spacious living area with wicker furniture, a chandelier, and large windows offering a view of palm trees and a balcony.

A table set for two on a beach with a view of the sea and distant islands.

11. Marriott Sanibel Harbour Resort & Spa

Punta Rassa

$223

$284 total

includes taxes & fees

Oct 15 - Oct 16

A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.

An outdoor dining area with thatched roofs and string lights, surrounded by tropical plants.

A hotel room with a bed, a sofa, a dining table with chairs, and a view of the sea through the window.

A multi-story hotel with a central atrium, palm trees, and a well-lit exterior.

12. The Lighthouse Resort Inn & Suites

Fort Myers Beach

$103

$135 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor seating area with tables and chairs, surrounded by palm trees and a thatched-roof structure.

A restaurant with a high wooden ceiling, hanging flags, and a variety of flags and decorations.

A nighttime view of a bar with a pool in front.

A bar with multiple liquor bottles and a large American flag in the background.

13. Dolphin Key Resort

Caloosahatchee

$90

$100 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

A modern hotel room with a wooden desk, a flat-screen TV, a chair, a wardrobe, and a framed picture on the wall.

A coffee station with two coffee machines, a coffee press, and various coffee cups and containers.

A hotel reception area with a check-in counter, a self-service kiosk, and a small kitchenette.

14. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

$103

$115 total

includes taxes & fees

Oct 11 - Oct 12

A modern hotel lobby with a seating area, a reception desk, and a dining area.

A Hampton Inn & Suites hotel entrance with a 'Welcome' sign, palm trees, and a well-lit facade.

A reception desk with a "Welcome to the Sun Shine State" sign, a wooden wall, and a minibar.

A hotel room with a bed, a desk, a chair, a TV, and a mirror.

15. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Caloosahatchee

$94

$105 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a large bed, two bedside tables with lamps, a nightstand, and a window with curtains.

A reception area with a counter, two chairs, and a coffee machine.

A compact kitchen with a wooden table, chairs, a refrigerator, a microwave, and cabinets.

A hotel room with a sofa, armchair, TV, and a small table with a vase.

16. Candlewood Suites Fort Myers Sanibel Gateway by IHG

South Fort Myers

$59

$66 total

includes taxes & fees

Oct 4 - Oct 5

A spacious lobby with large windows, several chairs, and potted plants.

A swimming pool with a curved edge, surrounded by a concrete deck. There are steps leading into the pool, and a building with multiple windows and balconies in the background.

A reception area with a wooden desk, a green sofa, and a tiled floor.

A multi-story hotel with a central atrium, palm trees, and a parking lot.

17. Allure Suites

McGregor

$77

$85 total

includes taxes & fees

Oct 3 - Oct 4

A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

A balcony with a wooden table, two glasses of red wine, and a bottle of wine. The balcony overlooks a beach and a building with multiple balconies.

A spacious lobby with a large wooden tree sculpture, comfortable seating areas, and large windows offering ocean views.

A hotel with multiple buildings, a pool area, and a beach.

18. Pink Shell Beach Resort and Marina

Fort Myers Beach

$220

$311 total

includes taxes & fees

Oct 19 - Oct 20

A beachside area with colorful Adirondack chairs, a fire pit, and a view of the water.

A bedroom with a large bed, a TV mounted on the wall, two bedside tables with lamps, and a window with blinds.

A modern kitchen with white cabinets, granite countertops, a built-in oven, and a microwave.

A balcony with wicker furniture, a pool, and a white fence.

19. Matlacha on Shoreview

Cape Coral

$65

$139 total

includes taxes & fees

Oct 5 - Oct 6

A turquoise building with a red door, surrounded by potted plants and flowers.

A person sitting on a sandy beach with the ocean in the background.

A sign for Angler's Inn in Melita, Florida, with a contact number.

A patio area with outdoor seating, a grill, and a view of a building with large windows.

20. Angler's Inn

Matlacha

$111

$213 total

includes taxes & fees

Oct 13 - Oct 14

View all properties

Go beyond your typical stay in Saint James City

Top neighborhoods in Saint James City

Manatee Bay

Manatee Bay

See properties

Learn more about Saint James City

The region around Saint James City is home to attractions such as Key West Express and J. N. Ding Darling National Wildlife Refuge.

See all hotels in Saint James City

Check out reviews of Saint James City hotels guests love

Off the Charts Inn & Out Island Resort

Saint James City

10/10 Exceptional

The property was in the middle of a remodel so there were only 5 rooms available which made it very quiet. The unit was very clean. The amazing thing about the property was the canal in the back. The manatees were swimming around everyday. They were awesome to see. One evening there were dolphins playing in the canal. There was a great restaurant within walking distance that had great food, drinks and live music every night.

Bobbie

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Fort Myers Beach

10/10 Exceptional

I would stay here again in a minute! Conveniently located just off Fort Myers Beach, next to Walmart, bus station, and main highway. Staff was exceptional with kindness and immediate response to requests. Hotel is clean clean clean! Breakfast was yummy and had different choices daily. I’m a late breakfast eater so having a refrigerator and microwave in my room was convenient for heating breakfast up later in morning after grabbing it early. Book here..you won’t be sorry!

Dennette

Sanibel Island Beach Resort

Mid Island

10/10 Exceptional

Linda

Island Inn

West End

10/10 Exceptional

Ava

The Westin Cape Coral Resort At Marina Village

Pelican

10/10 Exceptional

danica

Residence Inn by Marriott Fort Myers Sanibel

Fort Myers

10/10 Exceptional

elisa

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

10/10 Exceptional

Lina

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Fort Myers Beach

10/10 Exceptional

Morris

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Caloosahatchee

10/10 Exceptional

Jack

Pink Shell Beach Resort and Marina

Fort Myers Beach

10/10 Exceptional

This is a wonderful place, the adult pool was priceless because of so many children. Food was exceptional for a resort, the only real gripe is the drink prices. 9 bucks for a draft Modelo in a plastic cup. I had two mixed drinks and the wife two Mocktails and it was $60 dollars. I get it, its a resort but they are making a killing off the booze, I noticed many folks just brought their own because of this. Lower the price and you will sell more.

TIMOTHY KEVIN

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Siesta Isle

10/10 Exceptional

Brian

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Fort Myers

10/10 Exceptional

Michael

A marina with boats docked, surrounded by palm trees and a building with a red-tiled roof.

A waterfront property with a wooden deck, outdoor seating, and a covered patio area.

A bar area with a counter, stools, and ceiling fans.

A marina with docked boats, a covered area with umbrellas, and a bridge in the background.

Matanzas Inn Bayside Resort and Marina

Fort Myers Beach

10/10 Exceptional

Dolphin Key Resort

Caloosahatchee

10/10 Exceptional

Clint

An outdoor patio with wicker furniture, a fire feature, and string lights.

A pool area with a hot tub, lounge chairs, and palm trees.

A hotel with a clear entrance, a covered waiting area, and a sign indicating a clearance height of 10'-3".

A modern kitchen with a central island, bar stools, and hanging pendant lights.

Hilton Garden Inn Ft Myers

Villas

10/10 Exceptional

Anonymous traveler

Angler's Inn

Matlacha

10/10 Exceptional

Evelyn

Marriott Sanibel Harbour Resort & Spa

Punta Rassa

10/10 Exceptional

Lina

A beach view from a balcony with a pool, palm trees, and a building with a balcony.

A multi-story hotel with balconies, a sandy beach in front, and palm trees.

A balcony with a TV, a chair, and a view of a beach with a pier.

A spacious kitchen with a dining area, a ceiling fan, and a view of the outdoors.

Edison Beach House

Fort Myers Beach

10/10 Exceptional

Robert

Frequently Asked Questions

What accommodations do travelers like in Saint James City?

Guests like Margaritaville Beach Resort Fort Myers , Lani Kai Beachfront Resort and Sanibel Island Beach Resort.

Can I book a refundable hotel in Saint James City?

If you want the flexibility to change your plans to Saint James City, most properties offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in Saint James City if I want a vacation rental instead of a traditional hotel?

If you want a good alternative to a hotel, browse our selection of 52 vacation homes.

What will the weather in Saint James City be like during my trip?

August and July are typically the warmest months in Saint James City when the average temp is 83°F. January and February are the coldest months when the average temperature is 68°F. August and June are the months with the most rain.

Why should I book my Saint James City accommodation with Hotels.com?

There are lots of reasons to book your Saint James City trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.