Street signs for Waterfront, Fishing/Tour Boats, and Street.

Hotels near Main Street Hyannis Hyannis

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Where to stay near Main Street Hyannis?

A multi-story hotel with balconies, a flat roof, and a clear sky.

An indoor swimming pool with clear water, surrounded by black chairs and tables.

A man sitting at a table with a laptop, overlooking a pool area with chairs and tables.

A hotel room with two beds, a desk, a chair, a lamp, and a nightstand with a phone and a small table.

1. Hyannis Travel Inn

0.2 km from Main Street Hyannis

Joseph

$99

$113 total

includes taxes & fees

Sep 23 - Sep 24

A neatly arranged bedroom with a large bed, a bedside table, a chair, a TV mounted on the wall, and a window with blinds.

A dining area with black leather chairs, dark wooden tables, and white bowls.

A two-story building with a covered porch and a sign for Sea Street Inn.

A modern kitchen with stainless steel appliances, a central island, pendant lighting, and a textured wall.

2. Sea Street Inn

1.5 km from Main Street Hyannis

Frank

$264

$302 total

includes taxes & fees

Oct 12 - Oct 13

A residential area with houses, a well-maintained lawn, and a body of water in the background.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and a view of the sea.

A modern living room with a sofa, armchairs, a coffee table, and a dining area with chairs and a table. There are framed pictures on the wall, a lamp, and a view of the sea through large windows.

A balcony with blue lounge chairs and a wooden deck overlooking a lake.

3. Green Harbor Resort

2.1 km from Main Street Hyannis

Doreen

$185

$235 total

includes taxes & fees

Sep 28 - Sep 29

A stone fire pit with four white Adirondack chairs around it, overlooking a marina with boats.

A row of wicker chairs with cushions, a map on the wall, and a view of the outside through a window.

A marina with multiple boats docked, surrounded by residential houses and greenery.

A corridor with wooden flooring, wicker furniture, and large windows.

4. Anchor In Distinctive Waterfront Lodging

0.6 km from Main Street Hyannis

Maureen

$161

$212 total

includes taxes & fees

Oct 4 - Oct 5

A covered outdoor seating area with wicker furniture and a glass-top table.

A compact kitchen with a microwave, a window, a sink, and a radiator.

A restaurant with wooden tables and chairs, a counter with a cash register, and large windows offering a view of the outside.

A hotel room with two beds, a red armchair, and a window with curtains.

5. Cape Cod Harbor House Inn

0.4 km from Main Street Hyannis

Jeanne

$135

$155 total

includes taxes & fees

Oct 4 - Oct 5

A poolside area with a wooden pergola, green seating, and a sign reading "LE JARDIN BLEU".

A row of white bicycles with brown seats and wicker baskets, parked in front of a white building with black railings and large windows.

A modern indoor dining area with a wooden table, chairs, and a decorative wall with string lights.

A bartender pouring a drink into a gold cocktail shaker.

6. Uncommoner Hotel by Reverie Boutique Collection

1.9 km from Main Street Hyannis

"We had a great stay (4 nights) at the Uncommoner Hotel. We stayed in a Moroccan King room. The staff was welcoming and helpful. The room was beautifully decorated and large. It has a refrigerator, a Keurig coffee machine, a clothes steamer, and everything you would expect or need. The hotel is very well maintained, The indoor and outdoor pools are great. The grounds are beautifully landscaped around the restaurant and a pond, including fire pits and multiple seating areas. We will definitely...

Silvia

$119

$141 total

includes taxes & fees

Oct 13 - Oct 14

A hotel room with a large bed, a chair, a table, and a window with curtains.

A coffee station with a Bunn branded juice dispenser, a coffee machine, and a variety of coffee pods.

A house with white siding, a balcony with white railings, and two flower boxes with plants.

A brick pathway leading to a building with a sign reading "SeaCoast Inn" and the number 33.

7. SeaCoast Inn

0.1 km from Main Street Hyannis

Laura

$109

$125 total

includes taxes & fees

Oct 6 - Oct 7

A covered walkway with wooden flooring, planter boxes with plants, and a white exterior wall.

A spacious, modern restaurant with a long counter and multiple seating areas.

A hallway with a sign reading 'ASCEND COLLECTION,' a wooden planter with plants, and a reflective floor.

A living room with a sofa, coffee table, and patterned chair. There are two wall-mounted ship wheels and a framed picture on the wall.

8. Heritage House Inn on Cape Cod, an Ascend Collection Hotel

0.3 km from Main Street Hyannis

Dennis

$127

$145 total

includes taxes & fees

Oct 12 - Oct 13

A pool area with lounge chairs and flags.

A restaurant interior with tables and chairs, decorative lanterns, and potted plants.

A sports complex with a tennis court, parking area, and buildings with multiple floors and a sloped roof.

A beachside seating area with Adirondack chairs arranged around a stone fire pit.

9. The Cove at Yarmouth by Westgate Resorts

2.1 km from Main Street Hyannis

Michael

$149

$171 total

includes taxes & fees

Sep 23 - Sep 24

An outdoor patio with wicker furniture, a fire pit, and umbrellas.

A reception area with a sign reading "Welcome to the Patriot State" and a counter with a "Hilton" sign.

A breakfast bar with waffle makers, a fruit bowl, and a coffee station.

An indoor swimming pool with clear signage, lounge chairs, and a tiled floor.

10. Hampton Inn & Suites Cape Cod-West Yarmouth

1.7 km from Main Street Hyannis

Thuy

$122

$140 total

includes taxes & fees

Oct 18 - Oct 19

An indoor swimming pool with a brick wall, a white table with chairs, and a large window.

A Courtyard Resort sign, a building with a brick facade, and a parking lot.

A reception area with a reception desk, a clock, a fire alarm, and a sign for the courtyard resort.

A multi-story hotel with a well-maintained lawn, outdoor seating area with chairs, and a wooden deck.

11. Courtyard Resort

0.3 km from Main Street Hyannis

Jake

$101

$116 total

includes taxes & fees

Oct 1 - Oct 2

An indoor swimming pool with a wooden ceiling, potted plants, and lounge chairs.

A two-story building with a prominent tower, large windows, and a well-lit entrance.

A hotel room with a bed, a chair, a table with two glasses of wine, a lamp, and a window with a view of a lake.

A beachside table with two chairs, a blue umbrella, and a white tablecloth.

12. Bayside Resort Hotel

2.3 km from Main Street Hyannis

dena

$166

$201 total

includes taxes & fees

Oct 18 - Oct 19

An indoor swimming pool with a high ceiling and large windows.

A café interior with a wooden counter, a menu board, and a refrigerated display.

A modern bar area with a curved wooden counter, multiple stools, and a display case with beverages.

13. Courtyard By Marriott Cape Cod Hyannis

1.7 km from Main Street Hyannis

Alexis

$191

$219 total

includes taxes & fees

Oct 12 - Oct 13

A marina with boats docked, a wooden pier, and residential buildings in the background.

An outdoor dining area with white picket fencing, tables, and chairs.

A motel with a two-story structure, a covered parking area, and a small adjacent building.

14. Cape Cod Inn

0.2 km from Main Street Hyannis

Jerry

$102

$117 total

includes taxes & fees

Oct 6 - Oct 7

A modern conference room with a long table, chairs, a flat-screen TV, and pendant lighting.

A reception area with a wooden reception desk, a digital kiosk, and a fireplace.

A Fairfield by Marriott hotel with a large sign, a covered entrance, and a building with a tower.

A hotel room with a bed, a TV, a sofa, a lamp, and a chair.

15. Fairfield Inn & Suites by Marriott Cape Cod Hyannis

2.3 km from Main Street Hyannis

Kevin

$173

$198 total

includes taxes & fees

Oct 14 - Oct 15

An outdoor seating area with wooden furniture and a fire pit, surrounded by trees and a gravel path.

A row of white buildings with balconies, outdoor seating, and flower beds.

A lobby with a wooden floor, a reception desk, a large window, and a ceiling fan.

A decorative shark sculpture with the text "Cape Sands Inn" at a beachside location.

16. Cape Sands Inn

1.9 km from Main Street Hyannis

Sheng

$82

$93 total

includes taxes & fees

Sep 23 - Sep 24

An outdoor patio with round tables and chairs, a fire pit, and a covered seating area with string lights.

A lobby with a stone wall, a TV, and seating areas.

A modern lounge area with a stone wall, a flat-screen TV, and comfortable seating.

A DoubleTree hotel with a brick facade and a large sign.

17. Doubletree by Hilton Cape Cod - Hyannis

0.9 km from Main Street Hyannis

ashwini

$192

$220 total

includes taxes & fees

Oct 23 - Oct 24

A long dining table with chairs, a kitchen area, and a large window.

A reception area with a check-in counter, blue chairs, a waiting area, and a glass door leading to a dining area.

An indoor swimming pool with clear blue water, tiled walls, and a ceiling painted in blue.

A Comfort Inn hotel with a modern facade, large glass windows, and a clear sky.

18. Comfort Inn Hyannis - Cape Cod

0.3 km from Main Street Hyannis

Cindy

$107

$123 total

includes taxes & fees

Oct 22 - Oct 23

A gym with various cardio and strength training equipment, including treadmills, elliptical machines, and weight machines.

A conference room with multiple tables and chairs, equipped with microphones and projectors.

A spacious, modern interior with a high ceiling, a seating area with sofas, a desk with a computer, and a large TV screen.

A hotel room with two beds, a desk with a computer, a chair, and a window with curtains.

19. Holiday Inn Hyannis by IHG

2.9 km from Main Street Hyannis

Sharon

$144

$165 total

includes taxes & fees

Oct 4 - Oct 5

A two-story hotel with a curved facade, a balcony, and a sign indicating the lobby.

A waterfront hotel with a view of the marina and boats.

A resort pool area with multiple lounge chairs and umbrellas, a hot tub, and a large building in the background.

An outdoor seating area with wicker furniture, umbrellas, and a stone wall.

20. Hyannis Harbor Hotel

0.6 km from Main Street Hyannis

Ann Marie

$137

$172 total

includes taxes & fees

Oct 18 - Oct 19

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Compare popular hotels close to Main Street Hyannis

Property	Property class	Guest rating
Hyannis Travel Inn	9.6 Exceptional 1,018 reviews	View
Sea Street Inn	9.8 Exceptional 46 reviews	View
Green Harbor Resort	9.6 Exceptional 374 reviews	View
Anchor In Distinctive Waterfront Lodging	9.4 Exceptional 1,001 reviews	View
Cape Cod Harbor House Inn	9.2 Wonderful 342 reviews	View

Other landmarks near Main Street Hyannis

A bronze statue of a man in a polo shirt standing in front of a building with a brick facade, white columns, and an American flag.

John F. Kennedy Hyannis Museum

8.8/10 (444 reviews)

The center of Hyannis is home to cultural attractions like John F. Kennedy Hyannis Museum, so you might want to stop by during your stay. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches. If you want to experience more of the culture Hyannis has to offer, head to Main Street Hyannis, Hyannis Harbor, and Cape Cod Hospital.

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A model boat with a rope tied around it, displayed in a museum setting.

Cape Cod Maritime Museum

9.0/10 (16 reviews)

The center of Hyannis is home to cultural attractions like Cape Cod Maritime Museum, so you might want to stop by during your stay. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches. If you want to experience more of the culture Hyannis has to offer, head to Hyannis Harbor, Main Street Hyannis, and John F. Kennedy Hyannis Museum.

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A white church with a steeple and a sign for Saint Francis Xavier Sunday masses.

St. Francis Xavier Church

8.6/10 (58 reviews)

St. Francis Xavier Church is 0.3 mi (0.5 km) from central Hyannis, why not stop by during your stay. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.

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A memorial plaque with a bust of John F. Kennedy surrounded by a stone wall.

John F. Kennedy Memorial

9.0/10 (262 reviews)

If seeing the sights is on your list of things to do, head to John F. Kennedy Memorial— just one of the landmarks located 0.8 mi (1.3 km) from central Hyannis. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.

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Hyannis Armory

If you're planning a bit of sightseeing during your trip, head to Hyannis Armory— just one of the monuments in central Hyannis.

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Hyannis Youth & Community Center

8.2/10 (22 reviews)

Hyannis Youth & Community Center is 0.5 mi (0.9 km) from central Hyannis, why not stop by during your stay.

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Zion Union Heritage Museum

6.0/10 (1 review)

Zion Union Heritage Museum is 0.6 mi (0.9 km) from central Hyannis, why not stop by during your stay. If you want to experience more of the culture Hyannis has to offer, head to Cape Cod Melody Tent, John F. Kennedy Hyannis Museum, and Main Street Hyannis.

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Commotion Charters

6.0/10 (3 reviews)

Commotion Charters is 0.6 mi (0.9 km) from central Hyannis, why not stop by during your stay. Why not take a stroll along the beaches and watch the sunset while you're here? If you have fun at Commotion Charters, you'll love Cape Cod Maritime Museum, just a short walk away.

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