Street signs for Waterfront, Fishing/Tour Boats, and Street.

Hotels near Main Street Hyannis Hyannis

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Where to stay near Main Street Hyannis?

A multi-story hotel with balconies, a flat roof, and a clear sky.

A hotel room with two beds, a desk, a chair, a lamp, and a nightstand with a phone and a small table.

A reception area with a counter, a seated area with a lamp, and framed pictures on the wall.

An indoor swimming pool with clear water, surrounded by black chairs and tables.

1. Hyannis Travel Inn

0.2 km from Main Street Hyannis

Harry

$109

$125 total

includes taxes & fees

Sep 28 - Sep 29

A hotel room with a large bed, a chair, a table, and a window with curtains.

A hotel corridor with patterned carpet, a decorative ceiling light, and a view of parked cars outside.

A coffee station with a Bunn branded juice dispenser, a coffee machine, and a variety of coffee pods.

A house with white siding, a balcony with white railings, and two flower boxes with plants.

2. SeaCoast Inn

0.1 km from Main Street Hyannis

Laura

$109

$125 total

includes taxes & fees

Oct 6 - Oct 7

A pool area with lounge chairs and flags.

A sports complex with a tennis court, parking area, and buildings with multiple floors and a sloped roof.

A restaurant interior with tables and chairs, decorative lanterns, and potted plants.

A modern building with a sloped roof, large windows, and a covered entrance area with seating.

3. The Cove at Yarmouth by Westgate Resorts

2.1 km from Main Street Hyannis

BELKIS

$139

$159 total

includes taxes & fees

Oct 25 - Oct 26

A covered walkway with wooden flooring, planter boxes with plants, and a white exterior wall.

An indoor swimming pool with lounge chairs, a stone wall, and a mezzanine level.

A spacious, modern restaurant with a long counter and multiple seating areas.

A hallway with a sign reading 'ASCEND COLLECTION,' a wooden planter with plants, and a reflective floor.

4. Heritage House Inn on Cape Cod, an Ascend Collection Hotel

0.3 km from Main Street Hyannis

Bryan

$127

$145 total

includes taxes & fees

Oct 18 - Oct 19

An indoor swimming pool with a wooden ceiling, potted plants, and lounge chairs.

A beachside table with two chairs, a blue umbrella, and a white tablecloth.

A hotel room with a bed, a chair, a table with two glasses of wine, a lamp, and a window with a view of a lake.

A two-story building with a prominent tower, large windows, and a well-lit entrance.

5. Bayside Resort Hotel

2.3 km from Main Street Hyannis

Adriana

$140

$172 total

includes taxes & fees

Oct 27 - Oct 28

A marina with boats docked, a wooden pier, and residential buildings in the background.

A hotel room with a large bed, two bedside tables, a desk with a chair, a mirror, and two wall lamps.

A motel with a two-story structure, a covered parking area, and a small adjacent building.

6. Cape Cod Inn

0.2 km from Main Street Hyannis

Jerry

$102

$117 total

includes taxes & fees

Sep 28 - Sep 29

An outdoor patio with round tables and chairs, a fire pit, and a covered seating area with string lights.

A large indoor swimming pool with multiple lanes, surrounded by rows of chairs and a high ceiling with large windows.

A lobby with a stone wall, a TV, and seating areas.

A modern lounge area with a stone wall, a flat-screen TV, and comfortable seating.

7. Doubletree by Hilton Cape Cod - Hyannis

0.9 km from Main Street Hyannis

ashwini

$141

$161 total

includes taxes & fees

Oct 25 - Oct 26

A house with a brick exterior and a covered patio area.

A two-story wooden house with a white picket fence, an American flag, and a sign indicating a business on the ground floor.

A four-poster bed with a footboard, a bedside table with a lamp, a wooden bench, and a dresser with a mirror.

A bathroom with a bathtub, a shower, and a toilet. There are towels hanging on the wall.

8. Sea Breeze Inn

1.8 km from Main Street Hyannis

"The Sea Breeze was an economical stay in the Cape. Other options were super expensive so the Sea Breeze was great for our 3 night stay. The property is a little older but everything was clean and functional. The property is a 4 minute walk to the beach, 1 mile from the Kennedy Compound and 2.5 miles from Main Street. Boston is just 1.5 hours, Provincetown at the end of the cape is just an hour drive. We enjoyed Kate's Ice Cream, breakfast at the Daily Paper and supper ate Pizza Borbone...

Phillip

$120

$137 total

includes taxes & fees

Oct 23 - Oct 24

A beach with clear skies and gentle waves.

A fire pit with chairs arranged around it, set on sandy ground with a wooden fence and foliage in the background.

A reception area with a wooden counter, a blue accent wall, and striped armchairs.

A grassy area with blue Adirondack chairs arranged around a central fire pit. In the background, there are two buildings with a playground structure.

9. Sunbird Cape Cod Resort

2.3 km from Main Street Hyannis

"We had such a wonderful stay at Sunbird Cape Cod Resort! The kids absolutely loved the playground and all the outdoor games and activities — there was always something fun to do for the whole family. The breakfast was also surprisingly delicious with so many great options to start the day. The atmosphere was relaxing, family-friendly, and perfect for a Cape Cod getaway. We will definitely be coming back again!"

Eva

$101

$116 total

includes taxes & fees

Oct 5 - Oct 6

An indoor swimming pool with clear glass walls, a metal roof, and several Adirondack chairs around the pool.

A dining area with a table and chairs, a sofa, a TV mounted on the wall, and a plant on a table.

A building with a glass entrance and a covered patio area.

A reception area with a wooden reception desk, a clock, a framed picture, and a door.

10. Econo Lodge West Yarmouth on Cape Cod

1.5 km from Main Street Hyannis

Dawn

$80

$91 total

includes taxes & fees

Sep 30 - Oct 1

A neatly arranged bedroom with a large bed, a bedside table, a chair, a TV mounted on the wall, and a window with blinds.

A kitchen counter with a knife and a cutting board, a sign with a flower, and a view of a dining area through glass doors.

A two-story building with a covered porch and a sign for Sea Street Inn.

A modern kitchen with stainless steel appliances, a central island, pendant lighting, and a textured wall.

11. Sea Street Inn

1.5 km from Main Street Hyannis

Frank

$276

$316 total

includes taxes & fees

Oct 25 - Oct 26

A residential area with houses, a well-maintained lawn, and a body of water in the background.

A balcony with blue lounge chairs and a wooden deck overlooking a lake.

A coastal house with a white porch and a large window.

A modern living room with a sofa, armchairs, a coffee table, and a dining area with chairs and a table. There are framed pictures on the wall, a lamp, and a view of the sea through large windows.

12. Green Harbor Resort

2.1 km from Main Street Hyannis

Doreen

$169

$215 total

includes taxes & fees

Oct 1 - Oct 2

A stone fire pit with four white Adirondack chairs around it, overlooking a marina with boats.

A corridor with wooden flooring, wicker furniture, and large windows.

A marina with multiple boats docked, surrounded by residential houses and greenery.

A row of wicker chairs with cushions, a map on the wall, and a view of the outside through a window.

13. Anchor In Distinctive Waterfront Lodging

0.6 km from Main Street Hyannis

Jovian

$161

$212 total

includes taxes & fees

Oct 4 - Oct 5

A covered outdoor seating area with wicker furniture and a glass-top table.

A restaurant with wooden tables and chairs, a counter with a cash register, and large windows offering a view of the outside.

A compact kitchen with a microwave, a window, a sink, and a radiator.

A hotel room with two beds, a red armchair, and a window with curtains.

14. Cape Cod Harbor House Inn

0.4 km from Main Street Hyannis

Jeanne

$135

$155 total

includes taxes & fees

Oct 4 - Oct 5

A poolside area with a wooden pergola, green seating, and a sign reading "LE JARDIN BLEU".

A bartender pouring a drink into a gold cocktail shaker.

A bar area with a patterned wall, wicker chairs, and a tiled floor.

A row of white bicycles with brown seats and wicker baskets, parked in front of a white building with black railings and large windows.

15. Uncommoner Hotel by Reverie Boutique Collection

1.9 km from Main Street Hyannis

Richard

$119

$141 total

includes taxes & fees

Oct 13 - Oct 14

An outdoor patio with wicker furniture, a fire pit, and umbrellas.

A breakfast bar with waffle makers, a fruit bowl, and a coffee station.

An indoor swimming pool with clear signage, lounge chairs, and a tiled floor.

A reception area with a sign reading "Welcome to the Patriot State" and a counter with a "Hilton" sign.

16. Hampton Inn & Suites Cape Cod-West Yarmouth

1.7 km from Main Street Hyannis

robert

$122

$140 total

includes taxes & fees

Oct 13 - Oct 14

A modern conference room with a long table, chairs, a flat-screen TV, and pendant lighting.

A hotel room with a bed, a TV, a sofa, a lamp, and a chair.

A modern reception area with a desk, chairs, a fireplace, and a decorative plant.

A Fairfield by Marriott hotel with a large sign, a covered entrance, and a building with a tower.

17. Fairfield Inn & Suites by Marriott Cape Cod Hyannis

2.3 km from Main Street Hyannis

Kevin

$152

$174 total

includes taxes & fees

Oct 25 - Oct 26

An indoor swimming pool with a high ceiling and large windows.

A café interior with a wooden counter, a menu board, and a refrigerated display.

A modern bar area with a curved wooden counter, multiple stools, and a display case with beverages.

18. Courtyard By Marriott Cape Cod Hyannis

1.7 km from Main Street Hyannis

Alexis

$136

$156 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor seating area with wooden furniture and a fire pit, surrounded by trees and a gravel path.

A row of white buildings with balconies, outdoor seating, and flower beds.

A neatly made bed with white linens, a painting of a sailboat on the wall, and a door leading to a balcony.

A decorative shark sculpture with the text "Cape Sands Inn" at a beachside location.

19. Cape Sands Inn

1.9 km from Main Street Hyannis

Barry

$81

$92 total

includes taxes & fees

Sep 28 - Sep 29

A long dining table with chairs, a kitchen area, and a large window.

A reception area with a check-in counter, blue chairs, a waiting area, and a glass door leading to a dining area.

An indoor swimming pool with clear blue water, tiled walls, and a ceiling painted in blue.

A hotel room with a bed, a desk with a flat-screen TV, a coffee maker, a microwave, a vacuum cleaner, and a sliding door to a balcony.

20. Comfort Inn Hyannis - Cape Cod

0.3 km from Main Street Hyannis

Cindy

$107

$123 total

includes taxes & fees

Oct 22 - Oct 23

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Compare popular hotels close to Main Street Hyannis

Property	Property class	Guest rating
Hyannis Travel Inn	9.6 Exceptional 1,019 reviews	View
SeaCoast Inn	9.0 Wonderful 886 reviews	View
The Cove at Yarmouth by Westgate Resorts	9.2 Wonderful 268 reviews	View
Heritage House Inn on Cape Cod, an Ascend Collection Hotel	9.0 Wonderful 158 reviews	View
Bayside Resort Hotel	8.8 Excellent 1,606 reviews	View

Other landmarks near Main Street Hyannis

A bronze statue of a man in a polo shirt standing in front of a building with a brick facade, white columns, and an American flag.

John F. Kennedy Hyannis Museum

8.8/10 (444 reviews)

The center of Hyannis is home to cultural attractions like John F. Kennedy Hyannis Museum, so you might want to stop by during your stay. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches. If you want to experience more of the culture Hyannis has to offer, head to Main Street Hyannis, Hyannis Harbor, and Cape Cod Hospital.

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A model boat with a rope tied around it, displayed in a museum setting.

Cape Cod Maritime Museum

9.0/10 (16 reviews)

The center of Hyannis is home to cultural attractions like Cape Cod Maritime Museum, so you might want to stop by during your stay. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches. If you want to experience more of the culture Hyannis has to offer, head to Hyannis Harbor, Main Street Hyannis, and John F. Kennedy Hyannis Museum.

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A white church with a steeple and a sign for Saint Francis Xavier Sunday masses.

St. Francis Xavier Church

8.6/10 (58 reviews)

St. Francis Xavier Church is 0.3 mi (0.5 km) from central Hyannis, why not stop by during your stay. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.

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A memorial plaque with a bust of John F. Kennedy surrounded by a stone wall.

John F. Kennedy Memorial

9.0/10 (262 reviews)

If seeing the sights is on your list of things to do, head to John F. Kennedy Memorial— just one of the landmarks located 0.8 mi (1.3 km) from central Hyannis. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.

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Hyannis Armory

If you're planning a bit of sightseeing during your trip, head to Hyannis Armory— just one of the monuments in central Hyannis.

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Hyannis Youth & Community Center

8.2/10 (22 reviews)

Hyannis Youth & Community Center is 0.5 mi (0.9 km) from central Hyannis, why not stop by during your stay.

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Zion Union Heritage Museum

6.0/10 (1 review)

Zion Union Heritage Museum is 0.6 mi (0.9 km) from central Hyannis, why not stop by during your stay. If you want to experience more of the culture Hyannis has to offer, head to Cape Cod Melody Tent, John F. Kennedy Hyannis Museum, and Main Street Hyannis.

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Commotion Charters

6.0/10 (3 reviews)

Commotion Charters is 0.6 mi (0.9 km) from central Hyannis, why not stop by during your stay. Why not take a stroll along the beaches and watch the sunset while you're here? If you have fun at Commotion Charters, you'll love Cape Cod Maritime Museum, just a short walk away.

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