Street signs for Waterfront, Fishing/Tour Boats, and Street.

Hotels near Main Street Hyannis Hyannis

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Where to stay near Main Street Hyannis?

A multi-story hotel with balconies, a flat roof, and a clear sky.

A man sitting at a table with a laptop, overlooking a pool area with chairs and tables.

A hotel room with two beds, a desk, a chair, a lamp, and a nightstand with a phone and a small table.

A reception area with a counter, a seated area with a lamp, and framed pictures on the wall.

1. Hyannis Travel Inn

0.2 km from Main Street Hyannis

Harry

$109

$125 total

includes taxes & fees

Sep 28 - Sep 29

A stone fire pit with four white Adirondack chairs around it, overlooking a marina with boats.

A corridor with wooden flooring, wicker furniture, and large windows.

A row of wicker chairs with cushions, a map on the wall, and a view of the outside through a window.

A marina with multiple boats docked, surrounded by residential houses and greenery.

2. Anchor In Distinctive Waterfront Lodging

0.6 km from Main Street Hyannis

Maureen

$161

$212 total

includes taxes & fees

Oct 4 - Oct 5

An indoor swimming pool with a wooden ceiling, potted plants, and lounge chairs.

A beachside table with two chairs, a blue umbrella, and a white tablecloth.

A two-story building with a prominent tower, large windows, and a well-lit entrance.

A beach scene with a directional signpost and beach chairs.

3. Bayside Resort Hotel

2.3 km from Main Street Hyannis

dena

$140

$172 total

includes taxes & fees

Oct 27 - Oct 28

An outdoor patio with round tables and chairs, a fire pit, and a covered seating area with string lights.

A modern lounge area with a stone wall, a flat-screen TV, and comfortable seating.

A DoubleTree hotel with a brick facade and a large sign.

A lobby with a stone wall, a TV, and seating areas.

4. Doubletree by Hilton Cape Cod - Hyannis

0.9 km from Main Street Hyannis

ashwini

$139

$159 total

includes taxes & fees

Oct 25 - Oct 26

A beach with clear skies and gentle waves.

A fire pit with chairs arranged around it, set on sandy ground with a wooden fence and foliage in the background.

A reception area with a wooden counter, a blue accent wall, and striped armchairs.

A swimming pool with clear blue water, surrounded by a tiled deck and a building with a green roof in the background.

5. Sunbird Cape Cod Resort

2.3 km from Main Street Hyannis

"We had such a wonderful stay at Sunbird Cape Cod Resort! The kids absolutely loved the playground and all the outdoor games and activities — there was always something fun to do for the whole family. The breakfast was also surprisingly delicious with so many great options to start the day. The atmosphere was relaxing, family-friendly, and perfect for a Cape Cod getaway. We will definitely be coming back again!"

Eva

$101

$116 total

includes taxes & fees

Oct 5 - Oct 6

A sand sculpture of a sun with sunglasses and the text "Fun in the Sun" on a beach.

A grassy area with blue Adirondack chairs arranged around a central fire pit. In the background, there are two buildings with a playground structure.

6. Sunbird ANNEX Resort

2.3 km from Main Street Hyannis

Julia

$123

$141 total

includes taxes & fees

Oct 1 - Oct 2

A neatly arranged bedroom with a large bed, a bedside table, a chair, a TV mounted on the wall, and a window with blinds.

A kitchen counter with a knife and a cutting board, a sign with a flower, and a view of a dining area through glass doors.

A two-story building with a covered porch and a sign for Sea Street Inn.

A dining area with black leather chairs, dark wooden tables, and white bowls.

7. Sea Street Inn

1.5 km from Main Street Hyannis

Frank

$276

$316 total

includes taxes & fees

Oct 25 - Oct 26

A residential area with houses, a well-maintained lawn, and a body of water in the background.

A coastal house with a white porch and a large window.

A swimming pool with lounge chairs and umbrellas, surrounded by a fence and a view of the sea.

A modern living room with a sofa, armchairs, a coffee table, and a dining area with chairs and a table. There are framed pictures on the wall, a lamp, and a view of the sea through large windows.

8. Green Harbor Resort

2.1 km from Main Street Hyannis

Deborah

$199

$253 total

includes taxes & fees

Sep 28 - Sep 29

A covered outdoor seating area with wicker furniture and a glass-top table.

A hotel room with two beds, a red armchair, and a window with curtains.

A compact kitchen with a microwave, a window, a sink, and a radiator.

A two-story motel with a balcony on the upper floor, a parking lot in front, and a brick facade.

9. Cape Cod Harbor House Inn

0.4 km from Main Street Hyannis

Greg

$135

$155 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with a large bed, a chair, a table, and a window with curtains.

A hotel corridor with patterned carpet, a decorative ceiling light, and a view of parked cars outside.

A coffee station with a Bunn branded juice dispenser, a coffee machine, and a variety of coffee pods.

A brick pathway leading to a building with a sign reading "SeaCoast Inn" and the number 33.

10. SeaCoast Inn

0.1 km from Main Street Hyannis

Laura

$109

$125 total

includes taxes & fees

Oct 6 - Oct 7

A poolside area with a wooden pergola, green seating, and a sign reading "LE JARDIN BLEU".

A modern indoor dining area with a wooden table, chairs, and a decorative wall with string lights.

A row of white bicycles with brown seats and wicker baskets, parked in front of a white building with black railings and large windows.

A bar area with a patterned wall, wicker chairs, and a tiled floor.

11. Uncommoner Hotel by Reverie Boutique Collection

1.9 km from Main Street Hyannis

"We had a great stay (4 nights) at the Uncommoner Hotel. We stayed in a Moroccan King room. The staff was welcoming and helpful. The room was beautifully decorated and large. It has a refrigerator, a Keurig coffee machine, a clothes steamer, and everything you would expect or need. The hotel is very well maintained, The indoor and outdoor pools are great. The grounds are beautifully landscaped around the restaurant and a pond, including fire pits and multiple seating areas. We will definitely...

Silvia

$119

$141 total

includes taxes & fees

Oct 13 - Oct 14

A covered walkway with wooden flooring, planter boxes with plants, and a white exterior wall.

A hallway with a sign reading 'ASCEND COLLECTION,' a wooden planter with plants, and a reflective floor.

A living room with a sofa, coffee table, and patterned chair. There are two wall-mounted ship wheels and a framed picture on the wall.

A spacious, modern restaurant with a long counter and multiple seating areas.

12. Heritage House Inn on Cape Cod, an Ascend Collection Hotel

0.3 km from Main Street Hyannis

Dennis

$127

$145 total

includes taxes & fees

Oct 18 - Oct 19

A pool area with lounge chairs and flags.

A sports complex with a tennis court, parking area, and buildings with multiple floors and a sloped roof.

A modern building with a sloped roof, large windows, and a covered entrance area with seating.

A restaurant interior with tables and chairs, decorative lanterns, and potted plants.

13. The Cove at Yarmouth by Westgate Resorts

2.1 km from Main Street Hyannis

Michael

$139

$159 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor patio with wicker furniture, a fire pit, and umbrellas.

A snack and drink kiosk with a 'Treats' sign, a chalkboard menu, and shelves stocked with various snacks and beverages.

An indoor swimming pool with clear signage, lounge chairs, and a tiled floor.

A reception area with a sign reading "Welcome to the Patriot State" and a counter with a "Hilton" sign.

14. Hampton Inn & Suites Cape Cod-West Yarmouth

1.7 km from Main Street Hyannis

Thuy

$122

$140 total

includes taxes & fees

Oct 13 - Oct 14

A modern conference room with a long table, chairs, a flat-screen TV, and pendant lighting.

A modern reception area with a desk, chairs, a fireplace, and a decorative plant.

A hotel room with a bed, a TV, a sofa, a lamp, and a chair.

A reception area with a wooden reception desk, a digital kiosk, and a fireplace.

15. Fairfield Inn & Suites by Marriott Cape Cod Hyannis

2.3 km from Main Street Hyannis

Kevin

$152

$174 total

includes taxes & fees

Oct 25 - Oct 26

An indoor swimming pool with a high ceiling and large windows.

A café interior with a wooden counter, a menu board, and a refrigerated display.

A hotel reception area with a digital display showing today's weather and this week's forecast.

A modern bar area with a curved wooden counter, multiple stools, and a display case with beverages.

16. Courtyard By Marriott Cape Cod Hyannis

1.7 km from Main Street Hyannis

Alexis

$136

$156 total

includes taxes & fees

Oct 25 - Oct 26

A marina with boats docked, a wooden pier, and residential buildings in the background.

A hotel room with a large bed, two bedside tables, a desk with a chair, a mirror, and two wall lamps.

An outdoor dining area with white picket fencing, tables, and chairs.

A motel with a two-story structure, a covered parking area, and a small adjacent building.

17. Cape Cod Inn

0.2 km from Main Street Hyannis

Jerry

$102

$117 total

includes taxes & fees

Sep 28 - Sep 29

An outdoor seating area with wooden furniture and a fire pit, surrounded by trees and a gravel path.

A row of white buildings with balconies, outdoor seating, and flower beds.

A lobby with a wooden floor, a reception desk, a large window, and a ceiling fan.

A neatly made bed with white linens, a painting of a sailboat on the wall, and a door leading to a balcony.

18. Cape Sands Inn

1.9 km from Main Street Hyannis

Barry

$81

$92 total

includes taxes & fees

Sep 28 - Sep 29

A long dining table with chairs, a kitchen area, and a large window.

An indoor swimming pool with clear blue water, tiled walls, and a ceiling painted in blue.

A hotel room with a bed, a desk with a flat-screen TV, a coffee maker, a microwave, a vacuum cleaner, and a sliding door to a balcony.

A Comfort Inn hotel with a modern facade, large glass windows, and a clear sky.

19. Comfort Inn Hyannis - Cape Cod

0.3 km from Main Street Hyannis

Jarred

$107

$123 total

includes taxes & fees

Oct 22 - Oct 23

A gym with various cardio and strength training equipment, including treadmills, elliptical machines, and weight machines.

A hotel room with two beds, a desk with a computer, a chair, and a window with curtains.

A Holiday Inn hotel with a modern design, featuring a large parking lot and a well-maintained garden area.

A hotel room with a gray sofa, a television on a stand, a sliding door, a framed picture on the wall, and a lamp on a side table.

20. Holiday Inn Hyannis by IHG

2.9 km from Main Street Hyannis

Sharon

$134

$153 total

includes taxes & fees

Oct 25 - Oct 26

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Compare popular hotels close to Main Street Hyannis

Property	Property class	Guest rating
Hyannis Travel Inn	9.6 Exceptional 1,017 reviews	View
Anchor In Distinctive Waterfront Lodging	9.4 Exceptional 1,004 reviews	View
Bayside Resort Hotel	8.8 Excellent 1,606 reviews	View
Doubletree by Hilton Cape Cod - Hyannis	8.4 Very good 948 reviews	View
Sunbird Cape Cod Resort	7.8 Good 667 reviews	View

Other landmarks near Main Street Hyannis

A bronze statue of a man in a polo shirt standing in front of a building with a brick facade, white columns, and an American flag.

John F. Kennedy Hyannis Museum

8.8/10 (444 reviews)

The center of Hyannis is home to cultural attractions like John F. Kennedy Hyannis Museum, so you might want to stop by during your stay. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches. If you want to experience more of the culture Hyannis has to offer, head to Main Street Hyannis, Hyannis Harbor, and Cape Cod Hospital.

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A model boat with a rope tied around it, displayed in a museum setting.

Cape Cod Maritime Museum

9.0/10 (16 reviews)

The center of Hyannis is home to cultural attractions like Cape Cod Maritime Museum, so you might want to stop by during your stay. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches. If you want to experience more of the culture Hyannis has to offer, head to Hyannis Harbor, Main Street Hyannis, and John F. Kennedy Hyannis Museum.

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A white church with a steeple and a sign for Saint Francis Xavier Sunday masses.

St. Francis Xavier Church

8.6/10 (58 reviews)

St. Francis Xavier Church is 0.3 mi (0.5 km) from central Hyannis, why not stop by during your stay. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.

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A memorial plaque with a bust of John F. Kennedy surrounded by a stone wall.

John F. Kennedy Memorial

9.0/10 (262 reviews)

If seeing the sights is on your list of things to do, head to John F. Kennedy Memorial— just one of the landmarks located 0.8 mi (1.3 km) from central Hyannis. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.

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Hyannis Armory

If you're planning a bit of sightseeing during your trip, head to Hyannis Armory— just one of the monuments in central Hyannis.

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Hyannis Youth & Community Center

8.2/10 (22 reviews)

Hyannis Youth & Community Center is 0.5 mi (0.9 km) from central Hyannis, why not stop by during your stay.

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Zion Union Heritage Museum

6.0/10 (1 review)

Zion Union Heritage Museum is 0.6 mi (0.9 km) from central Hyannis, why not stop by during your stay. If you want to experience more of the culture Hyannis has to offer, head to Cape Cod Melody Tent, John F. Kennedy Hyannis Museum, and Main Street Hyannis.

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Commotion Charters

6.0/10 (3 reviews)

Commotion Charters is 0.6 mi (0.9 km) from central Hyannis, why not stop by during your stay. Why not take a stroll along the beaches and watch the sunset while you're here? If you have fun at Commotion Charters, you'll love Cape Cod Maritime Museum, just a short walk away.

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