Hotels in Santa Clara

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Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B
3.0 star property
Rio Hato
9.8 out of 10, Exceptional, (68 reviews)
Tropical relaxation awaits at this golf B&B featuring an outdoor pool, massage services, and a welcoming bar. Just minutes from Playa Blanca and Farallón Beach, with airport shuttle service available 24 hours for seamless travel.
The price is $122
$122 total
includes taxes & fees
Jun 2 - Jun 3
Villa Botero By Casa Mojito B&B

Hotel Coronado Inn

Hotel Coronado Inn
3.0 star property
Las Lajas
8.2 out of 10, Very Good, (83 reviews)
The price is $69
$76 total
includes taxes & fees
May 22 - May 23
Hotel Coronado Inn

Arganama Guesthouse

Arganama Guesthouse
3.0 star property
San Jose
The price is $180
$198 total
includes taxes & fees
May 19 - May 20
Arganama Guesthouse

Coronado Hideaway with Private Pool

Coronado Hideaway with Private Pool
2.0 star property
Las Lajas
Unwind in this serene vacation home featuring an outdoor pool and garden terrace near Teta Beach. With free WiFi and a short drive to Coronado Mall, this tropical retreat offers the perfect balance of relaxation and accessibility.
The price is $74
$111 total
includes taxes & fees
May 19 - May 20
Coronado Hideaway with Private Pool

San Carlos Surf Resort & Eco Lodge

San Carlos Surf Resort & Eco Lodge
3.0 star property
Costa Esmeralda
6.4 out of 10, (5 reviews)
The price is $78
$102 total
includes taxes & fees
May 19 - May 20
San Carlos Surf Resort & Eco Lodge

Bay View Hotel

Bay View Hotel
3.0 star property
San Carlos
6.6 out of 10, (101 reviews)
The price is $50
$55 total
includes taxes & fees
May 19 - May 20
Bay View Hotel

Manglar Lodge

Manglar Lodge
3.0 star property
San Carlos
9.0 out of 10, Wonderful, (214 reviews)
Experience the bay-side serenity at this San Carlos hotel where the on-site restaurant serves international dishes for all meals. Relax on the terrace or in the garden after exploring nearby Playa El Palmar, with free WiFi and parking for your convenience.
The price is $66
$73 total
includes taxes & fees
May 29 - May 30
Manglar Lodge

Casa Blanca

Casa Blanca
4.0 star property
San Carlos
4.0 out of 10, (1 review)
This charming guesthouse offers 2 restaurants and a rejuvenating spa featuring aromatherapy and deep-tissue massages. Cool off in the outdoor pool, grab snacks from the deli, and explore nearby Playa El Palmar and La Ensenada beaches.
The price is $89
$98 total
includes taxes & fees
May 19 - May 20
Casa Blanca

San Carlos Beach Inn

San Carlos Beach Inn
3.0 star property
San Carlos
8.4 out of 10, Very Good, (38 reviews)
Absorb breathtaking panoramas from the rooftop terrace at this beachside haven. Located near Playa El Palmar and Playa La Ensenada, the hotel features Panama Cafe serving 3 daily meals and free WiFi for seamless connectivity during your coastal escape.
The price is $32
$35 total
includes taxes & fees
May 20 - May 21
San Carlos Beach Inn

Hotel Eclipse

Hotel Eclipse
3.0 star property
San Jose
8.8 out of 10, Excellent, (82 reviews)
Bask in the sun at 2 outdoor pools or melt tension with deep-tissue massages. Blue Wolf Restaurant serves fusion meals while you're minutes from Los Cajones de Chame and Cerro Picacho. Free breakfast, WiFi, and parking enhance the value.
The price is $77
$84 total
includes taxes & fees
May 19 - May 20
Hotel Eclipse

Casa Caracol Boutique Hotel

Casa Caracol Boutique Hotel
2.0 star property
Las Uvas
8.8 out of 10, Excellent, (30 reviews)
The price is $99
$109 total
includes taxes & fees
May 19 - May 20
Casa Caracol Boutique Hotel

Cabañas Laguna Bella

Cabañas Laguna Bella
2.0 star property
La Laguna
10.0 out of 10, Exceptional, (1 review)
The price is $125
$163 total
includes taxes & fees
May 20 - May 21
Cabañas Laguna Bella

Gran Evenia Bijao & Convention Center

Gran Evenia Bijao & Convention Center
3.5 star property
Rio Hato
8.2 out of 10, Very Good, (1,009 reviews)
Unwind at this Rio Hato beach haven with 3 pools and 4 restaurants serving local fare. Near Playa Blanca and Farallón Beach, this all-inclusive escape offers a nightclub, 3 bars, and a free kids' club.
The price is $179
$196 total
includes taxes & fees
Jun 9 - Jun 10
Gran Evenia Bijao & Convention Center

Casa Madre Tierra

Casa Madre Tierra
3.0 star property
Los Llanitos
9.8 out of 10, Exceptional, (47 reviews)
Surrounded by nature near Valley of Square Trees, this serene mountain retreat offers complimentary breakfast and parking. Relax in the outdoor pool, enjoy a massage, or savor local flavors at the restaurant and bar. The tranquil terrace provides the perfect spot for unwinding.
The price is $173
$191 total
includes taxes & fees
May 19 - May 20
Casa Madre Tierra

The Golden Frog Inn

The Golden Frog Inn
3.0 star property
El Valle de Anton
9.6 out of 10, Exceptional, (271 reviews)
The price is $92
$102 total
includes taxes & fees
Jun 7 - Jun 8
The Golden Frog Inn

Hotel Campestre

Hotel Campestre
3.0 star property
El Valle de Anton
8.2 out of 10, Very Good, (261 reviews)
Wake up to stunning mountain vistas at this tranquil hotel in El Valle de Anton. Just minutes from Square Trees Nature Trail and Anton Valley Museum, you'll find lush gardens and a welcoming restaurant. Unwind with a drink at the bar while soaking in the natural beauty all around.
The price is $107
$118 total
includes taxes & fees
May 19 - May 20
Hotel Campestre

Hotel La Compania Del Valle

Hotel La Compania Del Valle
5.0 star property
El Valle de Anton
9.8 out of 10, Exceptional, (107 reviews)
Immerse yourself in El Valle de Anton's natural beauty while enjoying spa treatments, a seasonal outdoor pool, and rooftop terrace views. Just minutes from cultural attractions with convenient amenities like free WiFi and parking.
The price is $228
$251 total
includes taxes & fees
Jun 1 - Jun 2
Hotel La Compania Del Valle

Grand Decameron Panama, A Trademark All Inclusive Resort

Grand Decameron Panama, A Trademark All Inclusive Resort
3.5 star property
Rio Hato
7.2 out of 10, Good, (1,007 reviews)
Escape to this all-inclusive resort with free cabanas on the beach. Enjoy seafood at El Canal, unwind with massages, or play volleyball and tennis. With 8 bars and a marina, you're just minutes from Farallón Beach and Playa Blanca.
The price is $150
$165 total
includes taxes & fees
May 24 - May 25
Grand Decameron Panama, A Trademark All Inclusive Resort

Acuarela Hostal - Hostel

Acuarela Hostal - Hostel
2.0 star property
Rio Hato
8.6 out of 10, Excellent, (27 reviews)
Wake to a complimentary breakfast before strolling 5 minutes to golden sands for snorkeling adventures. This beach hostel offers convenient amenities including free WiFi and parking, plus outdoor spaces with a terrace and garden to unwind after exploring Playa Blanca.
The price is $18
$42 total
includes taxes & fees
May 19 - May 20
Acuarela Hostal - Hostel

Caracoral Hotel Boutique & Spa

Caracoral Hotel Boutique & Spa
3.0 star property
El Valle de Anton
9.6 out of 10, Exceptional, (65 reviews)
Tucked in El Valle de Anton, this tranquil boutique hotel offers rejuvenating body wraps and facials at the onsite spa. Enjoy the sauna, steam room, and restaurant after exploring nearby Butterfly Heaven and Sunday Market.
The price is $179
$197 total
includes taxes & fees
May 21 - May 22
Caracoral Hotel Boutique & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Clara

The region around Santa Clara is home to attractions such as Playa Blanca and Santa Clara Beach.

Santa Clara, Panama

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Frequently asked questions

What accommodations do travelers recommend in Santa Clara?
Can I book a refundable hotel in Santa Clara?
If you're looking for the flexibility to change your plans to Santa Clara, most accommodations provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Santa Clara if I want a vacation home instead of a traditional hotel?
If you're looking for a good alternative to a hotel, look over our selection of 6 vacation homes.
What will the weather in Santa Clara be like during my visit?
With an average temperature of 78°F, Santa Clara is a great place if you want to enjoy the sunshine year all year long.
Why should I book my Santa Clara hotel through Hotels.com?
There are plenty of reasons to book your Santa Clara travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.