Hotels in Perryville
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Tonight
Sep 3 - Sep 4Tomorrow
Sep 4 - Sep 5This weekend
Sep 4 - Sep 6Next weekend
Sep 11 - Sep 13Top 5 hotels in Perryville at a glance
- 1. Holiday Inn Express & Suites Perryville by IHG — 2.5-star hotel in Perryville. Guest rating: 9.2/10 — Wonderful.
- 2. Super 8 by Wyndham Perryville — 2-star hotel in Perryville. Guest rating: 8.4/10 — Very Good.
- 3. Perryville RV Resort — 2-star hotel in Perryville. Guest rating: 9.6/10 — Exceptional.
- 4. The Atrium - A Boutique Hotel — 2-star hotel in Perryville. Guest rating: 9.8/10 — Exceptional.
- 5. Days Inn by Wyndham Perryville — 2-star hotel in Perryville. Guest rating: 6.8/10.
Where to stay in Perryville?
1. Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
$91
$104 total
includes taxes & fees
Oct 4 - Oct 5
2. Super 8 by Wyndham Perryville
Super 8 by Wyndham PerryvillePerryville
$71
$81 total
includes taxes & fees
Sep 9 - Sep 10
3. Perryville RV Resort
Perryville RV ResortPerryville
$66
$76 total
includes taxes & fees
Sep 7 - Sep 8
4. The Atrium - A Boutique Hotel
The Atrium - A Boutique HotelPerryville
$84
$170 total
includes taxes & fees
Sep 5 - Sep 6
5. Days Inn by Wyndham Perryville
Days Inn by Wyndham PerryvillePerryville
$71
$82 total
includes taxes & fees
Sep 6 - Sep 7
6. Quality Inn Perryville I-55
Quality Inn Perryville I-55Perryville
$67
$77 total
includes taxes & fees
Sep 13 - Sep 14
8. The Mediterranean House 1858
The Mediterranean House 1858Perryville
$345
$626 total
includes taxes & fees
Sep 7 - Sep 8
9. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
$80
$85 total
includes taxes & fees
Sep 7 - Sep 8
10. Baymont by Wyndham Chester IL
Baymont by Wyndham Chester ILChester
$94
$104 total
includes taxes & fees
Sep 6 - Sep 7
11. Microtel Inn & Suites by Wyndham Sainte Genevieve
Microtel Inn & Suites by Wyndham Sainte GenevieveSte Genevieve
$89
$105 total
includes taxes & fees
Oct 4 - Oct 5
12. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHGMurphysboro
$114
$127 total
includes taxes & fees
Sep 9 - Sep 10
13. Triangle Inn Motel
Triangle Inn MotelSte Genevieve
$68
$79 total
includes taxes & fees
Oct 4 - Oct 5
14. Madison Inn Lodge
Madison Inn LodgeFredericktown
$88
$96 total
includes taxes & fees
Sep 11 - Sep 12
15. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
$93
$100 total
includes taxes & fees
Sep 6 - Sep 7
16. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
$89
$102 total
includes taxes & fees
Sep 9 - Sep 10
17. The Conner House B&B
The Conner House B&BPrairie du Rocher
$156
$173 total
includes taxes & fees
Sep 7 - Sep 8
18. Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
$80
$86 total
includes taxes & fees
Oct 4 - Oct 5
19. Sparta Motel Near St. Louis / Mississippi River IL
Sparta Motel Near St. Louis / Mississippi River ILSparta
$70
$85 total
includes taxes & fees
Sep 14 - Sep 15
20. Briarwood Inn of Sparta
Briarwood Inn of SpartaSparta
$89
$99 total
includes taxes & fees
Sep 4 - Sep 5
Get last-minute hotel deals in Perryville and save more
Sign in to unlock great savings.
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
$114
per night
$131 total
includes taxes & fees
$84
per night
$96 total
includes taxes & fees
$84
per night
$170 total
includes taxes & fees
Sign in for extra savings
$71
per night
$82 total
includes taxes & fees
$85
per night
$97 total
includes taxes & fees
$224
per night
$338 total
includes taxes & fees
Sign in for extra savings
The Mediterranean House 1858
The Mediterranean House 1858Perryville
$345
per night
$626 total
includes taxes & fees
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
$119
per night
$136 total
includes taxes & fees
$70
per night
$81 total
includes taxes & fees
Sign in for extra savings
$95
per night
$109 total
includes taxes & fees
$85
per night
$97 total
includes taxes & fees
$85
per night
$97 total
includes taxes & fees
$224
per night
$338 total
includes taxes & fees
Sign in for extra savings
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
$120
per night
$275 total
includes taxes & fees
$70
per night
$161 total
includes taxes & fees
Sign in for extra savings
$102
per night
$234 total
includes taxes & fees
$103
per night
$236 total
includes taxes & fees
$104
per night
$237 total
includes taxes & fees
Check out pet-friendly hotels in Perryville
$71
$81 total
includes taxes & fees
Sep 9 - Sep 10
$66
$76 total
includes taxes & fees
Sep 7 - Sep 8
$84
$170 total
includes taxes & fees
Sep 5 - Sep 6
$71
$82 total
includes taxes & fees
Sep 6 - Sep 7
You may also like hotels with pools in Perryville
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
$91
$104 total
includes taxes & fees
Oct 4 - Oct 5
$71
$81 total
includes taxes & fees
Sep 9 - Sep 10
$66
$76 total
includes taxes & fees
Sep 7 - Sep 8
$67
$77 total
includes taxes & fees
Sep 13 - Sep 14
$71
$82 total
includes taxes & fees
Sep 6 - Sep 7
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Perryville
Pet friendly
Family friendly
Our prices for hotels in Perryville are cheapest in December
Our prices for hotels in Perryville are cheapest in December
Price trends for hotels in Perryville
Pricing is based on two traveler single night rates
Top landmarks in Perryville
National Shrine of Our Lady of the Miraculous Medal
8.8/10 (19 reviews)
National Shrine of Our Lady of the Miraculous Medal is just one of the landmarks located 0.8 mi (1.2 km) from central Perryville, so you might want to stop by for a few pics during your trip.
Saint Marys Lake
Saint Marys Lake is 1 mi (1.7 km) from central Perryville, why not stop by during your stay.
County Lake State Wildlife Management Area
County Lake State Wildlife Management Area is 1.9 mi (3.1 km) from central Perryville, why not stop by during your stay. Want to stretch your legs some more? Head to Feltz Street Park, located nearby.
Perryville Country Club
6.6/10 (7 reviews)
You might want to practice your swing at Perryville Country Club, a golf course located 0.8 mi (1.3 km) from central Perryville.
Missouri's National Veterans Memorial
9.2/10 (14 reviews)
You might want to get your camera out and head to Missouri's National Veterans Memorial— just one of the landmarks located 2.3 mi (3.7 km) from central Perryville.
Feltz Street Park
Feltz Street Park is 0.3 mi (0.5 km) from central Perryville, why not stop by during your stay. Want to stretch your legs some more? Head to County Lake State Wildlife Management Area, located nearby.
Perryville City Hall
Perryville City Hall is worth a visit, located 0.8 mi (1.3 km) from central Perryville.
James M. Eddleman Millitary Museum
James M. Eddleman Millitary Museum is 2.3 mi (3.8 km) from central Perryville, why not stop by during your stay. If you want to experience more of the culture Perryville has to offer, head to National Shrine of Our Lady of the Miraculous Medal, Saint Marys Lake, and County Lake State Wildlife Management Area.
Perryville and related destinations
Perryville is well-known for its attractions such as National Shrine of Our Lady of the Miraculous Medal and Mark Twain National Forest.
See all hotels in Perryville
Check out reviews of Perryville hotels guests love
Tru By Hilton Cape Girardeau
10/10 Excellent
"Clean, quiet - and EV chargers both on and adjacent (Tesla Supercharger) to hotel property."
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
10/10 Excellent
"Room was clean. Bed was a very comfortable best pillows We’ve had the whole trip . close to several different places to eat."
Holiday Inn Express & Suites Perryville by IHG
10/10 Excellent
"Absolutely fabulous hotel!"
Microtel Inn & Suites by Wyndham Sainte Genevieve
8/10 Good
"The Breakfast items were a bit stale. Staff was not super helpful."
Perryville RV Resort
10/10 Excellent
"Great time"
Urban Lofts
10/10 Excellent
"Beautiful, clean property in the heart of city center. Many options for food and shopping within short walking distance."