Photo by Botak Jon

Hotels in Santa Fe de Antioquia

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Where to stay in Santa Fe de Antioquia?

Get last-minute hotel deals in Santa Fe de Antioquia and save more

Sign in to unlock great savings.
Showing deals for:Feb 20 - Feb 22
Showing deals for:Feb 27 - Mar 1
Showing deals for:Mar 18 - Mar 19

Check out hotels with a pool in Santa Fe de Antioquia

You may also like pet-friendly hotels in Santa Fe de Antioquia

You can also stay at hotels with a spa in Santa Fe de Antioquia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

When is the best time to visit Santa Fe de Antioquia?

Our prices for hotels in Santa Fe de Antioquia are cheapest in September
Price trends for hotels in Santa Fe de Antioquia
Pricing is based on two traveler single night rates
View properties in February
Currently viewing crowd sizes and weather for February.
Typical weather for Santa Fe de Antioquia
February
High 23°C / low 15°C. Cloudy most days.
View properties in February
23°
weather_cloudy
February, no crowd data, average high temperature 23 degrees Celsius, average low temperature 15 degrees Celsius. Cloudy most days.
15°
23°
weather_sleet
March, no crowd data, average high temperature 23 degrees Celsius, average low temperature 15 degrees Celsius. Rainy most days.
15°
24°
weather_sleet
April, no crowd data, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Rainy most days.
15°
24°
weather_sleet
May, no crowd data, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Rainy most days.
15°
25°
weather_sleet
June, no crowd data, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Rainy most days.
15°
25°
weather_sleet
July, no crowd data, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Rainy most days.
15°
26°
weather_sleet
August, no crowd data, average high temperature 26 degrees Celsius, average low temperature 15 degrees Celsius. Rainy most days.
15°
25°
weather_sleet
September, no crowd data, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Rainy most days.
15°
23°
weather_sleet
October, no crowd data, average high temperature 23 degrees Celsius, average low temperature 14 degrees Celsius. Rainy most days.
14°
22°
weather_sleet
November, no crowd data, average high temperature 22 degrees Celsius, average low temperature 14 degrees Celsius. Rainy most days.
14°
23°
weather_cloudy
December, no crowd data, average high temperature 23 degrees Celsius, average low temperature 14 degrees Celsius. Cloudy most days.
14°
23°
weather_cloudy
January, no crowd data, average high temperature 23 degrees Celsius, average low temperature 14 degrees Celsius. Cloudy most days.
14°
Monthly weather averages (˚C)

Top neighborhoods in Santa Fe de Antioquia

Zona Colonial

Santa Fe de Antioquia's Zona Colonial neighborhood is home to attractions such as Cathedral of Santa Fe de Antioquia and Bolivar Square.

Top landmarks in Santa Fe de Antioquia

Learn more about Santa Fe de Antioquia

Santa Fe de Antioquia is applauded for its cultural attractions such as Museo Juan del Corral and Casa Atanasio Girardot.

Pretty little colonial town just less than 2 hours drive from Medellín
Photo by Botak Jon
Open Photo by Botak Jon

Check out reviews of Santa Fe de Antioquia hotels guests love

Frequently asked questions

What accommodations do travelers recommend in Santa Fe de Antioquia?
Where can I find free parking at my hotel in Santa Fe de Antioquia?
Can I book a refundable hotel in Santa Fe de Antioquia?
If you need the flexibility to change your travel plans to Santa Fe de Antioquia, most accommodations offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Santa Fe de Antioquia if I want a vacation home instead of a traditional hotel?
If you're looking for a good alternative to a hotel, look over our selection of 5 vacation homes. You can also book one of 11 apartments or 7 villas.
What will the weather in Santa Fe de Antioquia be like during my visit?
August and July are typically the warmest months in Santa Fe de Antioquia when the average temp is 66°F. December and January are the coldest months when the average temperature is 64°F. May and April are the months with the most rain.
Why should I book my Santa Fe de Antioquia accommodation with Hotels.com?
There are lots of reasons to book your Santa Fe de Antioquia trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.