A bridge over a river with a sunset in the background.

Business Hotels in Florence

Where to?

Dates

November 2026

11

December 2026

I'm traveling for business

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Tonight

Nov 11 - Nov 12

Tomorrow

Nov 12 - Nov 13

This weekend

Nov 13 - Nov 15

Next weekend

Nov 20 - Nov 22

Business Hotels in Florence

A modern kitchen with wooden cabinets, a countertop with various appliances, and a view of the outdoors.

1. Holiday Inn Express Hotel & Suites FLORENCE NORTHEAST by IHG

Florence

$121 total

includes taxes & fees

Nov 22 - Nov 23

An indoor swimming pool with tiled steps and a sunlit room with chairs and a window.

2. Comfort Suites Florence Shoals Area

Florence

$101 total

includes taxes & fees

Nov 22 - Nov 23

A hotel lobby with a seating area, a reception desk, and a check-in counter.

3. Residence Inn Florence Marriott

East Florence

$154 total

includes taxes & fees

Dec 6 - Dec 7

A restaurant interior with a bar area, seating, and a counter with a coffee machine.

4. The Stricklin Hotel

Florence

$196 total

includes taxes & fees

Nov 12 - Nov 13

A spacious lobby with a blue sofa, a wooden table, and chairs. There is a TV on a stand and a painting on the wall.

5. Hampton Inn & Suites Florence-Downtown

Florence

$188 total

includes taxes & fees

Nov 29 - Nov 30

A hotel with a large pool area, a water tower, and a dome structure.

6. Renaissance Shoals Resort & Spa

East Florence

$309 total

includes taxes & fees

Nov 23 - Nov 24

A modern living room with a sofa, armchairs, a coffee table, and a TV.

7. Baymont by Wyndham Florence/Muscle Shoals

Florence

$78 total

includes taxes & fees

Nov 22 - Nov 23

A snack bar with shelves of snacks and a refrigerator with beverages.

8. Hampton Inn Florence Midtown near University of North Alabama

Florence

$150 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with a bed, a desk, a chair, a mirror, a painting, and a nightstand with a lamp.

9. Days Inn by Wyndham Muscle Shoals Florence

Muscle Shoals

$79 total

includes taxes & fees

Nov 12 - Nov 13

A spacious lobby with a reception desk, seating area, and a balcony.

10. Best Western Plus Tuscumbia Muscle Shoals Hotel and Suites

Tuscumbia

$113 total

includes taxes & fees

Nov 16 - Nov 17

A spacious lobby with seating areas, a reception desk, and large windows.

11. Clarion Inn Sheffield Muscle Shoals

Sheffield

$84 total

includes taxes & fees

Nov 15 - Nov 16

A modern hotel room with a large bed, a separate sitting area, a bathtub, and a view of the outdoors.

12. Red Roof Inn Muscle Shoals

Muscle Shoals

$67 total

includes taxes & fees

Nov 12 - Nov 13

A hotel room with a bed, a desk with chairs, a small kitchenette, and a TV.

13. Microtel Inn & Suites by Wyndham Tuscumbia/Muscle Shoals

Tuscumbia

$70 total

includes taxes & fees

Nov 25 - Nov 26

A spacious interior with a central staircase, a chandelier, and a view to the outdoors.

14. Spark by Hilton Tuscumbia Muscle Shoals

Tuscumbia

$92 total

includes taxes & fees

Nov 22 - Nov 23

A modern bathroom with a freestanding bathtub, a blue chair, and a wooden bench.

15. Comfort Inn & Suites Tuscumbia - Muscle Shoals

Tuscumbia

$112 total

includes taxes & fees

Dec 9 - Dec 10

A reception area with a reception desk, a seating area with chairs and a table, a plant, a lamp, a bulletin board, and a window with a view of the outside.

16. Keywest Inn - Tuscumbia/Muscle Shoals

Tuscumbia

$78 total

includes taxes & fees

Nov 12 - Nov 13

A modern hotel lobby with a central bar area, seating arrangements, and a welcoming sign.

17. Hampton Inn Pickwick Dam-At Shiloh Falls

Counce

$132 total

includes taxes & fees

Nov 22 - Nov 23

A reception area with a stone wall, a reception desk, and a door leading outside.

18. Econo Lodge Russellville

Russellville

$78 total

includes taxes & fees

Dec 10 - Dec 11

A reception area with a wooden counter, a seating area with a chair and a sofa, and a trash bin.

19. Heritage PLACE HOTEL IUKA

Iuka

$92 total

includes taxes & fees

Nov 12 - Nov 13

A spacious living area with a staircase, a flat-screen TV, and a seating area with a coffee table.

20. Best Western Plus Russellville Hotel & Suites

Russellville

$119 total

includes taxes & fees

Nov 28 - Nov 29

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Top neighborhoods in Florence

East Florence

A circular fountain with water jets in a park with green trees and benches.

East Florence

Florence's East Florence neighborhood has a host of places to visit such as Wilson Lake and Tennessee River.

Top landmarks in Florence

McFarland Park

McFarland Park is worth a visit, located 1.1 mi (1.7 km) from central Florence.

About the destination

Florence is a family-friendly place known for its restaurants. Nature lovers can visit Wilson Lake and Pickwick Lake. And while you're here, be sure to stop by Shoals Conference Center and Regency Square Mall.