Hotels logo

Hotels in Florence

October 2026
November 2026

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Where to stay in Florence?

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

1. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence
$89
$100 total
includes taxes & fees
Sep 20 - Sep 21
Park Inn by Radisson Florence, SC
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.
A modern lounge area with brick walls, large windows, and contemporary furniture.

2. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence
$103
$115 total
includes taxes & fees
Sep 21 - Sep 22
Hyatt Place Florence Downtown
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

3. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence
$101
$113 total
includes taxes & fees
Oct 11 - Oct 12
Comfort Inn & Suites Florence Center Area
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

4. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
Florence
$65
$72 total
includes taxes & fees
Sep 20 - Sep 21
Howard Johnson by Wyndham Florence
A hotel dining area with wooden tables and chairs, a fireplace, and a television.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A swimming pool with a metal ladder, lounge chairs, and a building with balconies.

5. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
Florence
$89
$100 total
includes taxes & fees
Sep 27 - Sep 28
Quality Inn & Suites Florence Civic Center
A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.
A large, two-story building with a central entrance flanked by columns, labeled "DIR FRANK B. LEE NURSING BUILDING."
A Holiday Inn Express & Suites hotel with a clear entrance, a covered parking area, and a well-maintained exterior.
A hotel lobby with a reception desk, a seating area with green sofas, and a dining area with tables and chairs.

6. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
Florence
$114
$138 total
includes taxes & fees
Sep 20 - Sep 21
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
An outdoor patio area with wicker furniture, a wooden pergola, and a barbecue setup.
A modern lobby with a round table, sofas, and a reception desk.
A modern lounge area with a fireplace, comfortable seating, and a decorative wall.
A modern kitchen with dark wood cabinets, a central island with a glass enclosure, and a white countertop.

7. Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence
Florence
$95
$116 total
includes taxes & fees
Oct 4 - Oct 5
Homewood Suites by Hilton Florence
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.
A lobby with leather sofas, a coffee table, potted plants, and a reception desk.
A corridor with shelves stocked with snacks and a frozen food display.

8. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
Florence
$118
$132 total
includes taxes & fees
Sep 24 - Sep 25
Hampton Inn & Suites Florence-North-I-95
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A modern cafeteria with long wooden tables, green chairs, and yellow accents.
An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

9. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
Florence
$81
$95 total
includes taxes & fees
Oct 4 - Oct 5
Spark by Hilton Florence North I-95, SC
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.
An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.
A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.
A modern coffee station with a counter, coffee machines, and a seating area with chairs.

10. Comfort Suites Florence I-95

Comfort Suites Florence I-95
Florence
$87
$102 total
includes taxes & fees
Oct 11 - Oct 12
Comfort Suites Florence I-95
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.
A modern lounge area with seating, tables, and a pool table.
A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.

11. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
Florence
$98
$115 total
includes taxes & fees
Sep 23 - Sep 24
Tru by Hilton Florence I-95
An indoor swimming pool with lounge chairs and exercise equipment.
A spacious lobby with a reception desk, seating area with patterned chairs, and a coffee station.
A hotel room with a bed, a desk, a green sofa, and a painting on the wall.

12. Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
Florence
$104
$123 total
includes taxes & fees
Sep 27 - Sep 28
Home2 Suites by Hilton Florence, SC
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.
A hotel room with a bed, a sofa, a desk, and a TV.
A modern breakfast area with a buffet setup, including a microwave, coffee maker, and various food items.
A hotel room with a bed, sofa, TV, and a desk.

13. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
Florence
$86
$96 total
includes taxes & fees
Sep 20 - Sep 21
La Quinta Inn & Suites by Wyndham Florence
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.
A swimming pool area with lounge chairs and umbrellas, surrounded by a white building with large windows.
A hotel entrance with a covered walkway, a brick pathway, and a well-maintained garden.

14. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
Florence
$135
$151 total
includes taxes & fees
Sep 20 - Sep 21
Staybridge Suites Florence - Civic Center by IHG
A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.
A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.
A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

15. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
Florence
$108
$127 total
includes taxes & fees
Sep 21 - Sep 22
SpringHill Suites by Marriott Florence
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A coffee station with two coffee machines and a display of coffee pods and cups.
A modern office space with a long table, two chairs, a desk with a computer, and a wall-mounted colorful artwork.
A modern restaurant with red upholstered chairs, a flat-screen TV mounted on the wall, and a ceiling with recessed lighting.

16. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Florence
$119
$133 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A hotel entrance with a stone facade, glass doors, and a number '501' above.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.
A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

17. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
Florence
$118
$132 total
includes taxes & fees
Sep 20 - Sep 21
Fairfield Inn & Suites by Marriott Florence I-20
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.
A lobby with a fireplace, seating area, and a television.
A hotel lobby with a reception desk, seating area, and a welcome mat.

18. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
Florence
$111
$124 total
includes taxes & fees
Sep 27 - Sep 28
Hampton Inn & Suites Florence Center
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A modern lounge area with a sofa, armchairs, and small tables.
A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

19. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
Florence
$118
$132 total
includes taxes & fees
Sep 19 - Sep 20
TownePlace Suites by Marriott Florence
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.
A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.
A hotel with a modern design, featuring multiple floors and a parking lot.
A modern hotel lobby with a fireplace, seating area, and a reception desk.

20. Residence Inn Marriott Florence

Residence Inn Marriott Florence
Florence
$115
$129 total
includes taxes & fees
Sep 27 - Sep 28
Residence Inn Marriott Florence
View all properties

Get last-minute hotel deals in Florence and save more

Sign in to unlock great savings.
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence
$119
per night
$133 total
includes taxes & fees
Park Inn by Radisson Florence, SC
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
Florence
$66
per night
$74 total
includes taxes & fees
Howard Johnson by Wyndham Florence
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence
$134
per night
$150 total
includes taxes & fees
Sign in for extra savings
Comfort Inn & Suites Florence Center Area
A hotel dining area with wooden tables and chairs, a fireplace, and a television.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A swimming pool with a metal ladder, lounge chairs, and a building with balconies.

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
Florence
$100
per night
$112 total
includes taxes & fees
Quality Inn & Suites Florence Civic Center
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A modern cafeteria with long wooden tables, green chairs, and yellow accents.
An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
Florence
$119
per night
$137 total
includes taxes & fees
Spark by Hilton Florence North I-95, SC
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A modern lounge area with a sofa, armchairs, and small tables.
A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
Florence
$122
per night
$137 total
includes taxes & fees
TownePlace Suites by Marriott Florence
A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.
A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.
A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
Florence
$129
per night
$150 total
includes taxes & fees
SpringHill Suites by Marriott Florence
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.
A hotel room with a bed, a sofa, a desk, and a TV.
A modern breakfast area with a buffet setup, including a microwave, coffee maker, and various food items.
A hotel room with a bed, sofa, TV, and a desk.

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
Florence
$117
per night
$131 total
includes taxes & fees
La Quinta Inn & Suites by Wyndham Florence
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.
A lobby with a fireplace, seating area, and a television.
A hotel lobby with a reception desk, seating area, and a welcome mat.

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
Florence
$144
per night
$161 total
includes taxes & fees
Sign in for extra savings
Hampton Inn & Suites Florence Center
A hotel room with a bed, bedside table with a phone, a desk with a chair, a TV mounted on the wall, and a window with curtains.
A modern kitchen with dark wood cabinets, stainless steel appliances, and a large juice dispenser.
A conference room with a wooden table, chairs, a TV, and a computer on a shelf.
A reception area with a wooden counter, a seating area with tables and chairs, and a large window with a view.

Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence
Florence
$69
per night
$77 total
includes taxes & fees
Microtel Inn & Suites by Wyndham Florence
A hotel lobby with a reception desk, potted plants, seating area, and large windows.
A building with large glass doors and windows, reflecting outdoor scenery.
A hotel lobby with a long reception desk, potted plants, and artwork on the walls.
A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a painting on the wall.

Days Inn by Wyndham Florence/I-95 North

Days Inn by Wyndham Florence/I-95 North
Florence
$60
per night
$68 total
includes taxes & fees
Days Inn by Wyndham Florence/I-95 North
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.
A modern lounge area with brick walls, large windows, and contemporary furniture.

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence
$169
per night
$189 total
includes taxes & fees
Hyatt Place Florence Downtown
A hotel with a modern design, multiple floors, and a parking lot.
A swimming pool with lounge chairs and a building with balconies in the background.
A reception area with a Best Western sign, a reception desk, a waiting area with a blue patterned sofa, and a potted plant.
A hotel room with a checkered sofa, a bed, a desk, and a framed picture on the wall.

Best Western Inn

Best Western Inn
Florence
$99
per night
$111 total
includes taxes & fees
Best Western Inn
A spacious lobby with a reception desk, seating area, and large windows.
An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.
A spacious lobby with a large fireplace, comfortable seating, and potted plants.
A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.

Hilton Garden Inn Florence

Hilton Garden Inn Florence
Florence
$144
per night
$161 total
includes taxes & fees
Hilton Garden Inn Florence
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.
An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.
A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.
A modern coffee station with a counter, coffee machines, and a seating area with chairs.

Comfort Suites Florence I-95

Comfort Suites Florence I-95
Florence
$133
per night
$153 total
includes taxes & fees
Comfort Suites Florence I-95

Check out pet-friendly hotels in Florence

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence
$89
$100 total
includes taxes & fees
Sep 20 - Sep 21
Park Inn by Radisson Florence, SC
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence
$101
$113 total
includes taxes & fees
Oct 11 - Oct 12
Comfort Inn & Suites Florence Center Area
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.
A modern lounge area with brick walls, large windows, and contemporary furniture.

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence
$103
$115 total
includes taxes & fees
Sep 21 - Sep 22
Hyatt Place Florence Downtown
A hotel dining area with wooden tables and chairs, a fireplace, and a television.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A swimming pool with a metal ladder, lounge chairs, and a building with balconies.

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
Florence
$89
$100 total
includes taxes & fees
Sep 27 - Sep 28
Quality Inn & Suites Florence Civic Center
An indoor swimming pool with lounge chairs and exercise equipment.
A spacious lobby with a reception desk, seating area with patterned chairs, and a coffee station.
A hotel room with a bed, a desk, a green sofa, and a painting on the wall.

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
Florence
$104
$123 total
includes taxes & fees
Sep 27 - Sep 28
Home2 Suites by Hilton Florence, SC
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.
A hotel room with a bed, a sofa, a desk, and a TV.
A modern breakfast area with a buffet setup, including a microwave, coffee maker, and various food items.
A hotel room with a bed, sofa, TV, and a desk.

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
Florence
$86
$96 total
includes taxes & fees
Sep 20 - Sep 21
La Quinta Inn & Suites by Wyndham Florence
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.
An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.
A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.
A modern coffee station with a counter, coffee machines, and a seating area with chairs.

Comfort Suites Florence I-95

Comfort Suites Florence I-95
Florence
$87
$102 total
includes taxes & fees
Oct 11 - Oct 12
Comfort Suites Florence I-95
A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.
A modern cafeteria with long wooden tables, green chairs, and yellow accents.
An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.
A hotel room with two beds, a desk with a chair, a television, and a window with curtains.

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
Florence
$81
$95 total
includes taxes & fees
Oct 4 - Oct 5
Spark by Hilton Florence North I-95, SC
An outdoor patio area with wicker furniture, a wooden pergola, and a barbecue setup.
A modern lobby with a round table, sofas, and a reception desk.
A modern lounge area with a fireplace, comfortable seating, and a decorative wall.
A modern kitchen with dark wood cabinets, a central island with a glass enclosure, and a white countertop.

Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence
Florence
$95
$116 total
includes taxes & fees
Oct 4 - Oct 5
Homewood Suites by Hilton Florence
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.
A lobby with a fireplace, seating area, and a television.
A hotel lobby with a reception desk, seating area, and a welcome mat.

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
Florence
$111
$124 total
includes taxes & fees
Sep 27 - Sep 28
Hampton Inn & Suites Florence Center
View all properties

You may also like hotels with pools in Florence

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence
$89
$100 total
includes taxes & fees
Sep 20 - Sep 21
Park Inn by Radisson Florence, SC
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.
A modern lounge area with brick walls, large windows, and contemporary furniture.

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence
$103
$115 total
includes taxes & fees
Sep 21 - Sep 22
Hyatt Place Florence Downtown
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence
$101
$113 total
includes taxes & fees
Oct 11 - Oct 12
Comfort Inn & Suites Florence Center Area
An indoor swimming pool with lounge chairs and exercise equipment.
A spacious lobby with a reception desk, seating area with patterned chairs, and a coffee station.
A hotel room with a bed, a desk, a green sofa, and a painting on the wall.

Home2 Suites by Hilton Florence, SC

Home2 Suites by Hilton Florence, SC
Florence
$104
$123 total
includes taxes & fees
Sep 27 - Sep 28
Home2 Suites by Hilton Florence, SC
A hotel dining area with wooden tables and chairs, a fireplace, and a television.
A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.
A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.
A swimming pool with a metal ladder, lounge chairs, and a building with balconies.

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
Florence
$89
$100 total
includes taxes & fees
Sep 27 - Sep 28
Quality Inn & Suites Florence Civic Center
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.
A hotel room with a bed, a sofa, a desk, and a TV.
A modern breakfast area with a buffet setup, including a microwave, coffee maker, and various food items.
A hotel room with a bed, sofa, TV, and a desk.

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
Florence
$86
$96 total
includes taxes & fees
Sep 20 - Sep 21
La Quinta Inn & Suites by Wyndham Florence
An outdoor patio area with wicker furniture, a wooden pergola, and a barbecue setup.
A modern lobby with a round table, sofas, and a reception desk.
A modern lounge area with a fireplace, comfortable seating, and a decorative wall.
A modern kitchen with dark wood cabinets, a central island with a glass enclosure, and a white countertop.

Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence
Florence
$95
$116 total
includes taxes & fees
Oct 4 - Oct 5
Homewood Suites by Hilton Florence
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.
A lobby with a fireplace, seating area, and a television.
A hotel lobby with a reception desk, seating area, and a welcome mat.

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
Florence
$111
$124 total
includes taxes & fees
Sep 27 - Sep 28
Hampton Inn & Suites Florence Center
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A coffee station with two coffee machines and a display of coffee pods and cups.
A modern office space with a long table, two chairs, a desk with a computer, and a wall-mounted colorful artwork.
A modern restaurant with red upholstered chairs, a flat-screen TV mounted on the wall, and a ceiling with recessed lighting.

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Florence
$119
$133 total
includes taxes & fees
Oct 18 - Oct 19
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.
An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.
A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.
A modern coffee station with a counter, coffee machines, and a seating area with chairs.

Comfort Suites Florence I-95

Comfort Suites Florence I-95
Florence
$87
$102 total
includes taxes & fees
Oct 11 - Oct 12
Comfort Suites Florence I-95
View all properties

Go beyond your typical stay in Florence

pet friendly image
Pet friendly
Pet friendly
Pool image
Pool
Pool
hot tub image
Hot tub
Hot tub
spa image
Spa
Spa
Family friendly image
Family friendly
Family friendly
apart-hotel image
Apart hotel
Apart hotel
Apartment image
Apart­ment
Apart­ment
Cottage image
Cottage
Cottage
waterpark image
Waterpark
Waterpark
Our prices for hotels in Florence are cheapest in December

Price trends for hotels in Florence

Pricing is based on two traveler single night rates
View properties in September

September

High 29°C / low 19°C. Sunny most days.
29°
19°
24°
14°
18°
8°
14°
6°
12°
3°
15°
5°
18°
8°
23°
12°
27°
17°
31°
21°
33°
23°
31°
22°
Monthly weather averages (˚C)

Top landmarks in Florence

A Florence Center building with a parking lot and a clear sky.

Florence Civic Center

8.0/10 (599 reviews)
Florence Civic Center is worth a visit, located 4.1 mi (6.6 km) from central Florence.
See properties
A shopping mall with a Magnolia Mall sign and a Burlington store across the street.

Magnolia Mall

8.2/10 (745 reviews)
If you like shopping, take time out to go to Magnolia Mall when in Florence.
See properties
A modern building with large windows and a crosswalk at an intersection.

Florence County Museum

7.8/10 (236 reviews)
The center of Florence is home to cultural attractions like Florence County Museum, so you might want to stop by during your stay. If you want to experience more of the culture Florence has to offer, head to Mcleod Regional Medical Center, Dr. Eddie Floyd Tennis Center, and Magnolia Mall.
See properties
A sunset over a calm river with a palm tree and grassy banks.

Palmetto Shores Lake

7.4/10 (96 reviews)
Palmetto Shores Lake is 5.2 mi (8.3 km) from central Florence, why not stop by during your stay.
See properties
A golf course with a clear sky, green grass, sand bunkers, and distant mountains.

The Traces Golf Club

7.6/10 (42 reviews)
You might want to practice your swing at The Traces Golf Club, a golf course located 7.2 mi (11.6 km) from central Florence.
See properties

Eastern Carolina Agricultural Fairgrounds

7.4/10 (162 reviews)
Why not give yourself a treat with a trip to Eastern Carolina Agricultural Fairgrounds, one of the family attractions located 7.3 mi (11.8 km) from central Florence. If you'd also like to explore some of the parks in Florence, head to Greenwood Baseball Park and Playground.
See properties

Dr. Eddie Floyd Tennis Center

You can catch an event at Dr. Eddie Floyd Tennis Center, located 1.6 mi (2.6 km) from central Florence. If you think Dr. Eddie Floyd Tennis Center is cool, you also might like CarolinaBank Field, located nearby.
See properties

Florence Veterans Park

8.0/10 (58 reviews)
If seeing the sights is on your list of things to do, head to Florence Veterans Park— just one of the landmarks located 3.9 mi (6.2 km) from central Florence. If you like Florence Veterans Park, you'll love Greenwood Baseball Park and Playground and Williamson Park, both just a short drive away.
See properties

Florence and related destinations

Between the intersections of two major highways lies a city where history and Southern culture blend seamlessly. The Florence County Museum showcases local heritage, while the War Between the States Museum offers a window into Civil War history. Downtown restaurants serve up authentic Southern cuisine worth the detour off I-95. Catch performances at Francis Marion University's Performing Arts Center, with acoustics rivaling larger cities. Florence Veterans Park provides a peaceful retreat with thoughtful memorials. Shoppers enjoy Magnolia Mall, while families visit Greenwood Baseball Park's playgrounds. The city's railroad heritage remains visible in its layout – a reminder of how this transportation hub became the beating heart of the Pee Dee region.

See all hotels in Florence
A historic brick building with arched windows and a river in the foreground.

Check out reviews of Florence hotels guests love

A Holiday Inn Express & Suites building with a modern design, featuring a prominent entrance with a covered walkway and stone pillars.
An outdoor patio with blue chairs and umbrellas, a stone-tiled floor, and a glass door leading to an indoor area.
A hotel room with two beds, a desk, a chair, a TV, and a framed picture on the wall.
A modern hotel lobby with a coffee bar, seating areas, and a reception desk.

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
Latta

10/10 Exceptional

United States
Kathryn
Holiday Inn Express & Suites Latta by IHG
A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.
A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.
A swimming pool area with lounge chairs and umbrellas, surrounded by a white building with large windows.
A hotel entrance with a covered walkway, a brick pathway, and a well-maintained garden.

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
Florence

10/10 Exceptional

United States
William
Staybridge Suites Florence - Civic Center by IHG
A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.
A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.
A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.
A modern lounge area with brick walls, large windows, and contemporary furniture.

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
Florence

10/10 Exceptional

United States
Arthur
Hyatt Place Florence Downtown
A building with two red doors, one labeled 'Office' and the other '101'. There is a welcome sign and a mailbox on the wall.
A compact kitchen with a dining area, a TV, and a small table.
A compact living space with a dining area, kitchenette, and seating area.
A room with a sofa, a small table, a chair, a lamp, and a door.

Affordable Suites Florence

Affordable Suites Florence
Florence

10/10 Exceptional

United States
MY CL
Affordable Suites Florence
A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.
A coffee station with two coffee machines and a display of coffee pods and cups.
A modern office space with a long table, two chairs, a desk with a computer, and a wall-mounted colorful artwork.
A modern restaurant with red upholstered chairs, a flat-screen TV mounted on the wall, and a ceiling with recessed lighting.

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Florence

10/10 Exceptional

United States
Tammie
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A hotel lobby with a reception desk, seating area, and a television screen.
A hotel room with a bed, a sofa, an ottoman, and a lamp.
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and multiple windows.
A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
Florence

10/10 Exceptional

United States
Roland
Comfort Inn & Suites Florence Center Area
An outdoor patio with wicker furniture, a fire feature, and string lights.
A modern living room with a flat-screen TV, dark wooden cabinets, a kitchen with stainless steel appliances, a dining area with patterned chairs, and a hallway leading to another room.
A modern interior with a large red 'M' sign, two grey armchairs, and a large window offering a view of the outdoors.
A modern kitchen with dark cabinets, stainless steel appliances, and pendant lighting.

The Mantissa Hotel

The Mantissa Hotel
Hartsville

10/10 Exceptional

United States
Kiana
The Mantissa Hotel
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.
A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.
A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
Florence

10/10 Exceptional

United States
Nichole
Park Inn by Radisson Florence, SC
A hotel entrance with a stone facade, glass doors, and a number '501' above.
An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.
A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.
A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
Florence

10/10 Exceptional

United States
Anonymous traveler
Fairfield Inn & Suites by Marriott Florence I-20
A spacious restaurant with high ceilings, hanging crystal chandeliers, and a variety of seating options including tables and booths.
A hotel room with a bed, desk, and chair, a small kitchenette, and a bathroom visible through an open door.
A multi-story brick building with a central entrance, large windows, and a flat roof.
A gym with treadmills, dumbbells, and a red exercise ball.

Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville
Hartsville

10/10 Exceptional

United States
Sean
Hampton Inn & Suites Hartsville
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.
A modern lounge area with a sofa, armchairs, and small tables.
A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.
A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
Florence

10/10 Exceptional

United States
Celia
TownePlace Suites by Marriott Florence
A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.
An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.
A lobby with leather sofas, a coffee table, potted plants, and a reception desk.
A corridor with shelves stocked with snacks and a frozen food display.

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
Florence

10/10 Exceptional

United States
Anonymous traveler
Hampton Inn & Suites Florence-North-I-95
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.
A hotel room with two beds, a desk, a TV, and a window with patterned curtains.
A lobby with a fireplace, seating area, and a television.
A hotel lobby with a reception desk, seating area, and a welcome mat.

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
Florence

10/10 Exceptional

United States
Shawn
Hampton Inn & Suites Florence Center
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.
A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.
A hotel with a modern design, featuring multiple floors and a parking lot.
A modern hotel lobby with a fireplace, seating area, and a reception desk.

Residence Inn Marriott Florence

Residence Inn Marriott Florence
Florence

10/10 Exceptional

United States
Anna
Residence Inn Marriott Florence
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.
A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.
A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
Florence

10/10 Exceptional

United States
Mike
Howard Johnson by Wyndham Florence
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.
A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.
A modern lounge area with seating, tables, and a pool table.
A snack kiosk with a variety of snacks and beverages, a sign for a 24/7 market, and a sign for local items.

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
Florence

10/10 Exceptional

United States
Robert
Tru by Hilton Florence I-95