Hotels in Mesilla

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Where to stay in Mesilla?

A pool area with a fountain, palm trees, and outdoor seating.

A spacious atrium with a central fountain, large potted plants, and a high ceiling with skylights.

A hallway with a tiled floor, a chandelier, potted plants, and a cross at the end.

A brick pathway lined with lush greenery and stone columns, leading to a covered area with a pergola.

Hotel Encanto de Las Cruces

Las Cruces

$106

$150 total

includes taxes & fees

Sep 20 - Sep 21

A lobby with a stone fireplace, sofas, and a glass coffee table.

A living room with a sofa, ottoman, TV, and a desk with a chair. There is a kitchen in the background.

An indoor swimming pool with a hot tub, tiled flooring, and a high ceiling with beams.

A courtyard with outdoor seating, a small tree, and a stone wall.

Drury Inn & Suites Las Cruces

Las Cruces

$94

$109 total

includes taxes & fees

Sep 13 - Sep 14

A Days Inn with a large sign, a flag, and a well-maintained entrance area.

An outdoor patio with wooden benches and a grill area.

A hotel room with a bed, desk, chair, and a painting on the wall.

A breakfast bar with coffee machines, a fruit bowl, and stacked paper cups.

Days Inn by Wyndham Las Cruces

Las Cruces

$48

$57 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with two beds, a desk with a TV, a chair, and two lamps.

A multi-story hotel with a central entrance, balconies, and a parking area.

A kitchen with a wooden counter, coffee machines, a microwave, and various appliances.

A living room with striped sofas, a glass coffee table, a fireplace, and a television.

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

Las Cruces

$54

$64 total

includes taxes & fees

Sep 20 - Sep 21

A spacious lobby with a central dining area, multiple seating options, and a modern chandelier.

A gym with treadmills, elliptical machines, and exercise bikes.

An indoor swimming pool with clear water, tiled edges, and a metal safety railing.

A lobby with teal armchairs, a coffee bar, and a dining area.

Hampton Inn & Suites Las Cruces I-10

Las Cruces

$118

$136 total

includes taxes & fees

Sep 12 - Sep 13

A spacious lobby with a high ceiling, a central chandelier, and large windows allowing natural light.

A hotel with a distinctive arched entrance and a clear sign reading "Hilton Garden Inn."

An outdoor patio with a built-in fireplace, surrounded by yellow cushioned chairs and a pergola overhead.

A spacious living room with a fireplace, leather sofas, a wooden coffee table with fruit, and patterned rugs.

Hilton Garden Inn Las Cruces

Las Cruces

$110

$127 total

includes taxes & fees

Sep 27 - Sep 28

A buffet area with a variety of baked goods, a coffee station, and a decorative plant.

A hotel room with two beds, wooden benches, a desk, and a chair.

A cozy living room with a wooden sofa and armchair, a wooden coffee table, and a patterned rug.

Best Western Mission Inn

Las Cruces

$72

$84 total

includes taxes & fees

Sep 9 - Sep 10

A hotel room with a bed, a TV mounted on the wall, a desk, and a sofa.

A pool area with lounge chairs and umbrellas, surrounded by a fence and a building with multiple windows and balconies.

A compact kitchenette with a microwave, a small sink, and a refrigerator.

A modern hotel with a flat roof, large windows, and a well-lit entrance.

Springhill Suites By Marriott Las Cruces

Las Cruces

$112

$129 total

includes taxes & fees

Sep 13 - Sep 14

A spacious indoor courtyard with tiled flooring, wooden furniture, and a balcony with a railing.

A dining area with a table and chairs, a remote control on a rug, and a door leading to another room.

A lobby with a tiled floor, a staircase, and a patterned wall hanging.

An indoor swimming pool with tiled flooring, a metal pool ladder, and a few lounge chairs.

Ramada Hotel & Conference Center by Wyndham Las Cruces

Las Cruces

$79

$92 total

includes taxes & fees

Sep 7 - Sep 8

A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows allowing natural light.

A reception desk with a marble top, framed pictures on the wall, a lamp, and a sign that reads "welcome to Las Cruces."

A spacious living area with a fireplace, comfortable seating, and a television.

A swimming pool with lounge chairs and a sunshade.

Hampton Inn & Suites Las Cruces I-25

Las Cruces

$106

$122 total

includes taxes & fees

Sep 27 - Sep 28

A hotel with a pool area, stone walls, and a palm tree.

A hotel room with a large bed, a desk, a dresser, a vanity with a mirror, and a painting on the wall.

A hotel with a central courtyard, multiple balconies, and a stone wall.

A reception desk with a wooden finish and decorative diamond patterns, a wall-mounted sign reading "Quality by Choice Hotels," and a framed picture on the wall.

Quality Inn & Suites Las Cruces - University Area

Las Cruces

$54

$64 total

includes taxes & fees

Sep 18 - Sep 19

A spacious hotel lobby with a modern design, featuring a reception desk, seating area, and potted plants.

A hotel room with a bed, a sofa, a desk, and a TV. There are framed pictures on the wall.

A hotel room with a large bed, a desk, a chair, a flat-screen TV, and a window with curtains.

An indoor swimming pool with clear water, a diving board, and lounge chairs.

Comfort Suites University Las Cruces

Las Cruces

$75

$88 total

includes taxes & fees

Sep 27 - Sep 28

An outdoor patio area with seating arrangements, including sofas and chairs, under a covered structure with a wooden ceiling.

A modern bar area with a long counter, bar stools, and a variety of liquor bottles.

A modern hotel lobby with a large sofa, armchairs, a coffee table, and a TV.

A Courtyard by Marriott hotel with a modern facade, multiple windows, and a covered entrance area.

Courtyard by Marriott Las Cruces at NMSU

Las Cruces

$130

$149 total

includes taxes & fees

Sep 13 - Sep 14

A living room with a sofa, two armchairs, a coffee table, and a lamp.

A hotel room with a bed, a desk with a television, a chair, and a wardrobe.

A modern dining area with tables and chairs, a kitchen area with appliances, and artwork on the walls.

A spacious lobby with a wooden floor, a reception desk, and a staircase with a green wall featuring a white leaf pattern.

Sleep Inn University

Las Cruces

$60

$70 total

includes taxes & fees

Sep 27 - Sep 28

A pool area with a hot tub, lounge chairs, and a lifeguard stand.

A hotel with a modern design, featuring a covered entrance and multiple floors.

A hotel room with a blue accent wall, a sofa, a bed, a desk, and a mirror.

A modern lobby with a sofa set, a small table with a potted plant, and a patterned wall.

Comfort Suites Las Cruces I-25 North

Las Cruces

$104

$124 total

includes taxes & fees

Sep 27 - Sep 28

A modern breakfast bar with a coffee machine, cereal and fruit options, and a yogurt, eggs, and milk dispenser.

A hotel room with a blue sofa, a wooden coffee table, two beds with white bedding, a headboard with a blue accent, a framed picture on the wall, and a window with a geometric blind.

A modern hotel lobby with a wooden ceiling, a seating area with a sofa and chairs, a small table with a computer, and a decorative wall with a map design.

A reception area with two reception desks, a blue geometric wall design, and a sign for 'Holiday Inn Express & Suites'.

Holiday Inn Express & Suites Las Cruces North by IHG

Las Cruces

$118

$136 total

includes taxes & fees

Sep 27 - Sep 28

A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.

A covered outdoor area with a patio, seating, and a small lawn.

A golf course with a mountain range in the background.

Comfort Inn & Suites Las Cruces Mesilla

Las Cruces

$93

$108 total

includes taxes & fees

Sep 27 - Sep 28

A multi-story building with a stone facade, a central entrance with a wooden archway, and a blue car parked in front.

A restaurant with a bar area, wooden chairs, a round table, and wall art.

An outdoor patio with stone pillars, green chairs, and a table.

A swimming pool with a curved edge, surrounded by palm trees and a building with a tiled roof.

Staybridge Suites Las Cruces by IHG

Las Cruces

$118

$136 total

includes taxes & fees

Sep 13 - Sep 14

A La Quinta Inn building with a sign, arched entrance, and well-lit windows.

A spacious lobby with a tiled floor, a reception desk, a bar area, and a staircase leading to upper floors.

A hotel courtyard with outdoor seating and a view of the building's exterior.

Two double beds with white linens and black headboards, a lamp, and two framed artworks on the wall.

Go 2 hotel by Reliance

Las Cruces

$40

$48 total

includes taxes & fees

Sep 18 - Sep 19

A hotel room with a large bed, two bedside lamps, a desk with a chair, a window with curtains, and a cityscape painting on the wall.

A hotel with a stone facade, a covered entrance, and a parking lot.

A dining area with multiple tables and chairs, a kitchen area with a refrigerator and a coffee machine, and a television mounted on the wall.

A hotel room with a sofa, a brown leather chair, a television, a desk with a lamp, a microwave, and a window with curtains.

Super 8 by Wyndham Las Cruces/White Sands Area

Las Cruces

$51

$60 total

includes taxes & fees

Sep 18 - Sep 19

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Go beyond your typical stay in Mesilla

Pet friendly

Pool

Hot tub

Family friendly

Cottage

Top landmarks in Mesilla

Mesillia Plaza

9.2/10 (5 reviews)

Get a few outdoor pics when passing through Mesillia Plaza, located 0.4 mi (0.7 km) from central Mesilla.

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Fountain Theatre

9.2/10 (19 reviews)

Fountain Theatre is 0.4 mi (0.7 km) from central Mesilla, why not stop by during your stay. If you enjoy the show and want to see another, Fountain Theater is just a short walk away.

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Fountain Theater

8.6/10 (14 reviews)

Fountain Theater is 0.5 mi (0.8 km) from central Mesilla, why not stop by during your stay. If you enjoy the show and want to see another, Fountain Theatre is just a short walk away.

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San Albino Basilica

You might want to get your camera out and head to San Albino Basilica— just one of the landmarks located 0.4 mi (0.7 km) from central Mesilla.

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Learn more about Mesilla

Centuries-old adobe buildings frame the historic plaza, where the Confederate Territory of Arizona once claimed its brief capital. Duck into La Posta de Mesilla, a former stagecoach stop now serving chile rellenos that locals defend with patriotic fervor. The Fountain Theatre screens independent films in what might be the oldest movie house in the Southwest. Browse galleries where artists capture desert light in ways that make you understand why Georgia O'Keeffe never left. The Mesilla Plaza, a National Historic Landmark, hosts festivals where the smell of roasting green chiles mingles with mariachi music. Las Cruces sits just next door with its Museum of Nature & Science when you've had your fill of history.

See all hotels in Mesilla

A rustic building with a wooden door, a hanging red chili, and a cactus plant.

Check out reviews of Mesilla hotels guests love

Drury Inn & Suites Las Cruces

10/10 Excellent

"I would recommend this place, slept well on very comfortable beds, breakfast was great. Over awesome place to stay."

Comfort Suites Las Cruces I-25 North

8/10 Good

"👍"

Days Inn by Wyndham Las Cruces

10/10 Excellent

"Everything was great."

Hampton Inn & Suites Las Cruces I-10

10/10 Excellent

"Good"

Holiday Inn Express & Suites Las Cruces North by IHG

10/10 Excellent

"The staff was exceptional. They accommodated our late checkout, which was a bonus. The breakfast was more than expected with freshly ground coffee beans! Yup you read it right."

Comfort Inn & Suites Las Cruces Mesilla

10/10 Excellent

"Nice well maintained hotel in the beautiful town of Las Cruces. Staff were helpful and responsive to queries and minor fixes. Slightly on the expensive side in terms of cost. Internet was a little slow at times. But overall very good."

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

10/10 Excellent

"Nice accommodations at a great price."

Frequently asked questions

What hotels do travelers like in Mesilla?

Guests like Hotel Encanto de Las Cruces, La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces.

Can I book a refundable hotel in Mesilla?

If you want the flexibility to change your travel plans to Mesilla, most accommodations offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where can I stay in Mesilla if I want a vacation rental instead of a traditional hotel?

If you're looking for a good alternative to a hotel, review our selection of 9 vacation homes.

What will the weather in Mesilla be like during my trip?

The warmest months in Mesilla are usually June and July with an average temp of 82°F. January and December are the chilliest months when the average temp is 48°F. The rainiest months are August and September.

Why should I book my Mesilla accommodation with Hotels.com?

There are plenty of reasons to book your Mesilla travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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