Hotels in Mesilla

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Check prices for these dates

Tonight
Oct 29 - Oct 30
Tomorrow
Oct 30 - Oct 31
This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Where to stay in Mesilla?

A courtyard with a central fountain, surrounded by palm trees and well-lit by ambient lighting.

1. Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
3.5 star property
Las Cruces
9.0 out of 10, Wonderful, (2,194 reviews)
Experience tranquility at this Las Cruces retreat featuring an outdoor pool, 3 bars, and a nightclub. Comfortable beds await after exploring nearby Mesilla Valley Mall or watching stunning sunsets over the mountains from your historic-charm accommodations.
The price is $107
$151 total
includes taxes & fees
Nov 15 - Nov 16
Hotel Encanto de Las Cruces
A lobby with a stone fireplace, sofas, and a glass coffee table.

2. Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (1,137 reviews)
Start your day with complimentary breakfast before exploring nearby vineyards. After sightseeing, unwind in the relaxing hot tub or take a dip in the indoor pool. Business travelers appreciate the free WiFi and parking, plus the attentive staff that guests consistently praise.
The price is $106
$123 total
includes taxes & fees
Nov 8 - Nov 9
Drury Inn & Suites Las Cruces
A Days Inn with a large sign, a flag, and a well-maintained entrance area.

3. Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces
2.5 star property
Las Cruces
8.2 out of 10, Very good, (1,652 reviews)
The price is $49
$58 total
includes taxes & fees
Nov 29 - Nov 30
Days Inn by Wyndham Las Cruces
A hotel room with two beds, a desk with a TV, a chair, and two lamps.

4. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
3.0 star property
Las Cruces
8.0 out of 10, Very good, (2,384 reviews)
Surrounded by breathtaking scenery, this quiet hotel offers an outdoor pool and comfortable beds near restaurants and stores. Just 15 minutes from New Mexico State University with easy freeway access, enjoy free breakfast and helpful staff.
The price is $60
$71 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
A coffee station with multiple coffee dispensers, a stack of disposable cups, and a sign indicating hot water and coffee options.

5. Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
2.5 star property
Las Cruces
9.0 out of 10, Wonderful, (1,000 reviews)
This business-friendly hotel offers free breakfast, WiFi, and parking in Las Cruces. Visit nearby Luna Rossa Winery & Pizzeria or Rio Grande Vineyards, then return to clean, comfortable rooms praised by travelers for their immaculate condition.
The price is $101
$117 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn & Suites Las Cruces I-10
A spacious lobby with a high ceiling, a central chandelier, and large windows allowing natural light.

6. Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (1,000 reviews)
Wake up refreshed at this Las Cruces haven with a 24-hour fitness center and soothing hot tub. Grab dinner at Great American Grille or unwind at the bar after exploring nearby Pan American Center and Aggie Memorial Stadium. Rooms include microwaves and refrigerators for added convenience.
The price is $111
$129 total
includes taxes & fees
Oct 31 - Nov 1
Hilton Garden Inn Las Cruces
A buffet area with a variety of baked goods, a coffee station, and a decorative plant.

7. Best Western Mission Inn

Best Western Mission Inn
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,242 reviews)
This serene Las Cruces hotel offers comfortable beds and a refreshing outdoor pool just minutes from campus. Enjoy the complimentary buffet breakfast before exploring nearby Luna Rossa Winery or local theaters, with free parking for added convenience.
The price is $80
$93 total
includes taxes & fees
Nov 1 - Nov 2
Best Western Mission Inn
A hotel room with a bed, a TV mounted on the wall, a desk, and a sofa.

8. Springhill Suites By Marriott Las Cruces

Springhill Suites By Marriott Las Cruces
3.0 star property
Las Cruces
8.4 out of 10, Very good, (1,000 reviews)
This modern hotel offers a peaceful atmosphere near Luna Rossa Winery and Rio Grande Vineyards. Start your day with free breakfast, then unwind in the outdoor pool and hot tub. Clean rooms with sofa beds welcome you back after exploring local shops.
The price is $105
$122 total
includes taxes & fees
Nov 15 - Nov 16
Springhill Suites By Marriott Las Cruces
A spacious indoor courtyard with tiled flooring, wooden furniture, and a balcony with a railing.

9. Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces
3.0 star property
Las Cruces
8.0 out of 10, Very good, (1,000 reviews)
Soak up relaxing vibes at this peaceful hotel featuring a beautiful courtyard, indoor pool, and full-service spa. Located near American Southwest Theater Company with helpful staff ready to enhance your stay.
The price is $88
$102 total
includes taxes & fees
Nov 2 - Nov 3
Ramada Hotel & Conference Center by Wyndham Las Cruces
A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows allowing natural light.

10. Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25
2.5 star property
Las Cruces
8.4 out of 10, Very good, (1,002 reviews)
The price is $98
$113 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn & Suites Las Cruces I-25
A hotel with a pool area, stone walls, and a palm tree.

11. Quality Inn & Suites Las Cruces - University Area

Quality Inn & Suites Las Cruces - University Area
2.5 star property
Las Cruces
7.0 out of 10, Good, (1,001 reviews)
Wake to a complimentary continental breakfast at this peaceful Las Cruces retreat. Located near Luna Rossa Winery and Rio Grande Vineyards, this hotel offers free WiFi and parking. Guests consistently praise the helpful staff and clean, quiet rooms.
The price is $51
$60 total
includes taxes & fees
Nov 28 - Nov 29
Quality Inn & Suites Las Cruces - University Area
A spacious hotel lobby with a modern design, featuring a reception desk, seating area, and potted plants.

12. Comfort Suites University Las Cruces

Comfort Suites University Las Cruces
2.5 star property
Las Cruces
8.0 out of 10, Very good, (1,000 reviews)
Find a tranquil retreat at this golf-adjacent Las Cruces hotel featuring an indoor pool and fitness center. Located near Pan American Center and Aggie Memorial Stadium, enjoy complimentary breakfast, WiFi, and parking while experiencing the attentive service that guests consistently praise.
The price is $79
$92 total
includes taxes & fees
Nov 29 - Nov 30
Comfort Suites University Las Cruces
An outdoor patio area with seating arrangements, including sofas and chairs, under a covered structure with a wooden ceiling.

13. Courtyard by Marriott Las Cruces at NMSU

Courtyard by Marriott Las Cruces at NMSU
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (606 reviews)
Moments from New Mexico State University, this modern hotel offers a refreshing outdoor pool and 24-hour fitness center. Grab breakfast or dinner at The Bistro, unwind at the bar, and appreciate free WiFi and parking during your Las Cruces adventure.
The price is $152
$175 total
includes taxes & fees
Nov 8 - Nov 9
Courtyard by Marriott Las Cruces at NMSU
A living room with a sofa, two armchairs, a coffee table, and a lamp.

14. Sleep Inn University

Sleep Inn University
2.5 star property
Las Cruces
7.6 out of 10, Good, (1,000 reviews)
This serene Las Cruces hotel offers an indoor pool, complimentary breakfast, WiFi, and parking. Guests consistently praise the quiet environment and helpful staff. Conveniently located near Pan American Center with clean, comfortable rooms.
The price is $59
$69 total
includes taxes & fees
Nov 29 - Nov 30
Sleep Inn University
A pool area with a hot tub, lounge chairs, and a lifeguard stand.

15. Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North
2.5 star property
Las Cruces
9.2 out of 10, Wonderful, (1,001 reviews)
This business-friendly hotel offers a rejuvenating indoor pool, hot tub, and spa services. Enjoy free breakfast, WiFi, and parking while exploring nearby Sonoma Ranch Golf Course. In-room refrigerators and microwaves add convenience to your southwestern stay.
The price is $103
$123 total
includes taxes & fees
Nov 22 - Nov 23
Comfort Suites Las Cruces I-25 North
A buffet with various food items, including omelets and other dishes, served in metal containers.

16. Holiday Inn Express & Suites Las Cruces North by IHG

Holiday Inn Express & Suites Las Cruces North by IHG
2.5 star property
Las Cruces
9.0 out of 10, Wonderful, (1,000 reviews)
Escape to Las Cruces where this hotel offers complimentary breakfast, WiFi, and parking. Relax in the indoor pool and hot tub after a workout in the fitness center. Clean rooms with microwaves and refrigerators await near Branigan Cultural Center and local attractions.
The price is $122
$141 total
includes taxes & fees
Oct 31 - Nov 1
Holiday Inn Express & Suites Las Cruces North by IHG
A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.

17. Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1,001 reviews)
Escape to the Mesilla area where an indoor pool and hot tub await after winery visits. Just 15 minutes from New Mexico State University, this hotel offers free breakfast, WiFi, and parking, plus in-room microwaves and refrigerators.
The price is $100
$116 total
includes taxes & fees
Nov 29 - Nov 30
Comfort Inn & Suites Las Cruces Mesilla
A multi-story building with a stone facade, a central entrance with a wooden archway, and a blue car parked in front.

18. Staybridge Suites Las Cruces by IHG

Staybridge Suites Las Cruces by IHG
3.0 star property
Las Cruces
8.8 out of 10, Excellent, (1,000 reviews)
Experience Las Cruces from this welcoming hotel with an outdoor pool and hot tub for relaxing after your day. Near Sonoma Ranch Golf Course and Branigan Cultural Center, the property offers free breakfast, WiFi, and convenient parking.
The price is $118
$136 total
includes taxes & fees
Nov 22 - Nov 23
Staybridge Suites Las Cruces by IHG
A hotel room with a large bed, two bedside lamps, a desk with a chair, a window with curtains, and a cityscape painting on the wall.

19. Super 8 by Wyndham Las Cruces/White Sands Area

Super 8 by Wyndham Las Cruces/White Sands Area
2.0 star property
Las Cruces
7.2 out of 10, Good, (1,000 reviews)
Refresh in the seasonal outdoor pool at this convenient Las Cruces hotel near New Mexico State University. Enjoy free breakfast, WiFi, and parking, plus easy access to Sonoma Ranch Golf Course and Red Hawk Golf Club.
The price is $51
$60 total
includes taxes & fees
Nov 27 - Nov 28
Super 8 by Wyndham Las Cruces/White Sands Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Go beyond your typical stay in Mesilla

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Top landmarks in Mesilla

Mesillia Plaza

9.2/10 (5 reviews)
Get a few outdoor pics when passing through Mesillia Plaza, located 0.4 mi (0.7 km) from central Mesilla.
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Learn more about Mesilla

Centuries-old adobe buildings frame the historic plaza, where the Confederate Territory of Arizona once claimed its brief capital. Duck into La Posta de Mesilla, a former stagecoach stop now serving chile rellenos that locals defend with patriotic fervor. The Fountain Theatre screens independent films in what might be the oldest movie house in the Southwest. Browse galleries where artists capture desert light in ways that make you understand why Georgia O'Keeffe never left. The Mesilla Plaza, a National Historic Landmark, hosts festivals where the smell of roasting green chiles mingles with mariachi music. Las Cruces sits just next door with its Museum of Nature & Science when you've had your fill of history.

See all hotels in Mesilla
A rustic building with a wooden door, a hanging red chili, and a cactus plant.

Check out reviews of Mesilla hotels guests love

A lobby with a stone fireplace, sofas, and a glass coffee table.
Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
Las Cruces

10/10 Exceptional

Beds very comfortable and breakfast was fantastic
United States
Robert
Reviewed December 1, 2024
Drury Inn & Suites Las Cruces

Frequently Asked Questions

What hotels do travelers like in Mesilla?

Guests like Hotel Encanto de Las Cruces, Ramada Hotel & Conference Center by Wyndham Las Cruces and La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain.

Can I book a refundable hotel in Mesilla?

If you want the flexibility to change your travel plans to Mesilla, most accommodations offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where can I stay in Mesilla if I want a vacation rental instead of a traditional hotel?

If you're looking for a good alternative to a hotel, review our selection of 8 vacation homes.

What will the weather in Mesilla be like during my trip?

The warmest months in Mesilla are usually June and July with an average temp of 82°F. January and December are the chilliest months when the average temp is 48°F. The rainiest months are August and September.

Why should I book my Mesilla accommodation with Hotels.com?

There are plenty of reasons to book your Mesilla travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.