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Hotels in Louisiana

September 2026
15
October 2026

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This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Where to stay in Louisiana?

A gazebo with a table and benches, surrounded by trees and a body of water.
A hotel room with a bed, a desk, a chair, a television, a microwave, and a lamp.
A two-story building with a flat roof and a covered entrance. There are two cars parked in front, and a truck is visible on the left.
A hotel room with a desk, a television, a chair, a small refrigerator, a lamp, and a plant.

1. River's Edge Motel

River's Edge Motel
Louisiana
$83
$94 total
includes taxes & fees
Sep 16 - Sep 17
River's Edge Motel
A restaurant with a bar area, wooden flooring, checkered tablecloths, and a brick wall.
A row of multi-story buildings with a variety of storefronts, including a coffee shop and a restaurant.
A bedroom with a brick wall, a wooden bed, two bedside tables with lamps, and a ceiling fan.
A downtown area with a mix of historic and modern buildings, a prominent Mercantile Bank, and a view of a lake.

2. The Eagles Nest Inn

The Eagles Nest Inn
Louisiana
$113
$128 total
includes taxes & fees
Sep 19 - Sep 20
The Eagles Nest Inn
A cozy living area with a leather sofa, a wooden coffee table, and a patterned armchair. A brick wall and wooden shelves with various items are visible.
A cozy interior with a brick wall, wooden shelves, and a leather chair.
A cozy indoor space with a round table and chairs, a bookshelf with books, and a ceiling fan.
A storefront with a sign reading "105 EAST WASHINGTON STREET PITTSFIELD, ILLINOIS 62363".

3. William Watson Hotel

William Watson Hotel
Pittsfield
$85
$93 total
includes taxes & fees
Sep 16 - Sep 17
William Watson Hotel
A hallway with a light blue wall, wooden shelves, and a door marked with the number 2.
A cozy living room with a wooden coffee table, a sofa, and a chair. There are potted plants and a television on the wall.
A cozy living room with a wooden dresser, a sofa, and a dining area with a table and chairs.
A bedroom with a large bed, a wooden floor, a ceiling with intricate patterns, and a hanging macrame wall decoration.

4. Monroe Street Suites

Monroe Street Suites
Pittsfield
$83
$91 total
includes taxes & fees
Sep 16 - Sep 17
Monroe Street Suites
A hallway with wooden doors leading to a dining area with a table and chairs.
A neatly made bed with a headboard, two bedside tables with lamps, a waste bin, and a window with curtains.
A kitchen with wooden cabinets, a granite countertop, and a built-in sink.
A hotel corridor with a wooden railing, a ceiling fan, and a lamp.

5. Green Acres Hotel

Green Acres Hotel
Pittsfield
$131
$144 total
includes taxes & fees
Sep 17 - Sep 18
Green Acres Hotel
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.
A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.
A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.
A hotel kitchen with a buffet setup, including a coffee station and various food items.

6. Best Western On The River

Best Western On The River
Hannibal
$110
$127 total
includes taxes & fees
Sep 20 - Sep 21
Best Western On The River
A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.
A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.
An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.
A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

7. Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
Hannibal
$110
$128 total
includes taxes & fees
Oct 11 - Oct 12
Sleep Inn & Suites Hannibal West
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.
A hotel entrance with a central fountain, large columns, and a clear sky.
A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.
A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

8. Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
Hannibal
$83
$96 total
includes taxes & fees
Oct 11 - Oct 12
Quality Inn & Suites Hannibal West
A hotel room with a bed, a sofa, a desk, and a lamp.
An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.
A restaurant with multiple tables and chairs, an exit sign, and a counter area.

9. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
$77
$92 total
includes taxes & fees
Sep 20 - Sep 21
Comfort Inn & Suites - Hannibal
A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.
A long hallway with a patterned carpet, wooden paneling on the walls, and a ceiling light.
A patio with red Adirondack chairs and a table, surrounded by a pebble border.
A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

10. Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
Hannibal
$62
$71 total
includes taxes & fees
Oct 4 - Oct 5
Super 8 by Wyndham Hannibal
An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.
A hotel room with a bed, a desk with a chair, a television, and a desk lamp.
A kitchen with a granite countertop, wooden cabinets, and a herringbone-patterned floor.
A clean, modern reception area with a reception desk, a clock, and a potted plant.

11. Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
Hannibal
$53
$61 total
includes taxes & fees
Sep 21 - Sep 22
Baymont by Wyndham Hannibal
A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.
A hotel room with two beds, a window with red curtains, an air conditioning unit, and two bedside lamps.
A coffee station with a coffee machine, cups, and a sign that says "RISE & SHINE."
A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

12. Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
Hannibal
$58
$67 total
includes taxes & fees
Sep 20 - Sep 21
Motel 6 Hannibal, MO
A bakery display with various baked goods and packaged snacks.
A hotel room with two beds, a bedside table with a lamp, a window with curtains, and a mirror on the wall.
A bathroom with a shower, tiled walls, and a wooden floor.
A sign for Rodeway Inn against a clear sky.

13. Rodeway Inn Pittsfield

Rodeway Inn Pittsfield
Pittsfield
$57
$63 total
includes taxes & fees
Oct 11 - Oct 12
Rodeway Inn Pittsfield
A hotel room with two beds, a wooden headboard, a nightstand with a phone and lamp, and a large sunset painting above the beds.
A corner kitchenette with a refrigerator, coffee maker, and food display.
A laundry room with a washing machine, dryer, and a shelf with detergent bottles.
A hotel with a covered entrance, a parking lot, and a clear sky.

14. Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
Hannibal
$61
$70 total
includes taxes & fees
Sep 20 - Sep 21
Days Inn by Wyndham Hannibal
A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.
A wooden table with a bottle of champagne, two glasses, and scattered rose petals.
A compact kitchen with a refrigerator, microwave, and sink.
A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.

15. Riverside Inn Hannibal

Riverside Inn Hannibal
Hannibal
$182
$245 total
includes taxes & fees
Sep 16 - Sep 17
Riverside Inn Hannibal
A spacious living area with a large bed, a dining table, and a brick wall.
A rooftop terrace with a brick wall, a metal railing, and a table with chairs.
A kitchen with wooden cabinets, a stainless steel stove, a dishwasher, and a brick wall.
A spacious living room with a brick wall, wooden beams, and a large window. There are two sofas and a coffee table.

16. Deck + River View: Loft in Downtown Hannibal

Deck + River View: Loft in Downtown Hannibal
Hannibal
$138
$265 total
includes taxes & fees
Sep 20 - Sep 21
Deck + River View: Loft in Downtown Hannibal
A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.
A large, two-story house with a porch and a sign indicating 'ONE WAY'.
A fireplace with decorative elements, framed pictures, and a vase of red flowers.
A cozy living room with a fireplace, a red armchair, a globe, and various framed pictures on the mantel.

17. Garden House Bed and Breakfast

Garden House Bed and Breakfast
Hannibal
$93
$107 total
includes taxes & fees
Sep 18 - Sep 19
Garden House Bed and Breakfast
A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.
A hotel room with two beds, a desk, a chair, and a telephone.
A kitchen with wooden cabinets, a granite countertop, and various food items and kitchen appliances.
A clean, modern reception area with a reception desk, a clock, and a potted plant.

18. Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
Hannibal
$61
$71 total
includes taxes & fees
Sep 16 - Sep 17
Howard Johnson BY Wyndham Hannibal
A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.
A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.
A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.
A swimming pool with lounge chairs and a covered seating area.

19. Lighthouse Inn & Suites

Lighthouse Inn & Suites
Hannibal
$199
$230 total
includes taxes & fees
Sep 16 - Sep 17
Lighthouse Inn & Suites
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Go beyond your typical stay in Louisiana

pet friendly image
Pet friendly
Pet friendly
Pool image
Pool
Pool
hot tub image
Hot tub
Hot tub
apart-hotel image
Apart hotel
Apart hotel
spa image
Spa
Spa
Family friendly image
Family friendly
Family friendly
Cottage image
Cottage
Cottage
Our prices for hotels in Louisiana are cheapest in September

Price trends for hotels in Louisiana

Pricing is based on two traveler single night rates
View properties in September

September

High 26°C / low 15°C. Sunny most days.
26°
15°
19°
9°
11°
3°
6°
-2°
2°
-6°
4°
-4°
12°
2°
17°
7°
23°
13°
28°
18°
30°
20°
29°
19°
Monthly weather averages (˚C)

Learn more about Louisiana

Louisiana is hailed for its riverfront while attractions include Mississippi River.

See all hotels in Louisiana
A river with a large, rusted metal bridge and a smaller bridge in the background.

Check out reviews of Louisiana hotels guests love

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.
A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.
An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.
A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
Hannibal

10/10 Exceptional

United States
Linda D
Sleep Inn & Suites Hannibal West
A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.
A wooden table with a bottle of champagne, two glasses, and scattered rose petals.
A compact kitchen with a refrigerator, microwave, and sink.
A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.

Riverside Inn Hannibal

Riverside Inn Hannibal
Hannibal

10/10 Exceptional

United States
Anonymous traveler
Riverside Inn Hannibal
A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.
A large, two-story house with a porch and a sign indicating 'ONE WAY'.
A fireplace with decorative elements, framed pictures, and a vase of red flowers.
A cozy living room with a fireplace, a red armchair, a globe, and various framed pictures on the mantel.

Garden House Bed and Breakfast

Garden House Bed and Breakfast
Hannibal

10/10 Exceptional

United States
Brad
Garden House Bed and Breakfast
A gazebo with a table and benches, surrounded by trees and a body of water.
A hotel room with a bed, a desk, a chair, a television, a microwave, and a lamp.
A two-story building with a flat roof and a covered entrance. There are two cars parked in front, and a truck is visible on the left.
A hotel room with a desk, a television, a chair, a small refrigerator, a lamp, and a plant.

River's Edge Motel

River's Edge Motel
Louisiana

10/10 Exceptional

United States
Jim & Judy
River's Edge Motel
A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.
A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.
A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.
A swimming pool with lounge chairs and a covered seating area.

Lighthouse Inn & Suites

Lighthouse Inn & Suites
Hannibal

10/10 Exceptional

United States
Chad
Lighthouse Inn & Suites
A hotel room with two beds, a wooden headboard, a nightstand with a phone and lamp, and a large sunset painting above the beds.
A corner kitchenette with a refrigerator, coffee maker, and food display.
A laundry room with a washing machine, dryer, and a shelf with detergent bottles.
A hotel with a covered entrance, a parking lot, and a clear sky.

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
Hannibal

10/10 Exceptional

United States
Kevin
Days Inn by Wyndham Hannibal
A cozy living area with a leather sofa, a wooden coffee table, and a patterned armchair. A brick wall and wooden shelves with various items are visible.
A cozy interior with a brick wall, wooden shelves, and a leather chair.
A cozy indoor space with a round table and chairs, a bookshelf with books, and a ceiling fan.
A storefront with a sign reading "105 EAST WASHINGTON STREET PITTSFIELD, ILLINOIS 62363".

William Watson Hotel

William Watson Hotel
Pittsfield

10/10 Exceptional

United States
Anonymous traveler
William Watson Hotel
A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.
A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.
A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.
A hotel kitchen with a buffet setup, including a coffee station and various food items.

Best Western On The River

Best Western On The River
Hannibal

10/10 Exceptional

United States
Jean
Best Western On The River
An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.
A hotel entrance with a central fountain, large columns, and a clear sky.
A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.
A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
Hannibal

10/10 Exceptional

United States
Pam
Quality Inn & Suites Hannibal West
A hotel room with a bed, a sofa, a desk, and a lamp.
An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.
A restaurant with multiple tables and chairs, an exit sign, and a counter area.

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal

10/10 Exceptional

United States
Donald
Comfort Inn & Suites - Hannibal
A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.
A long hallway with a patterned carpet, wooden paneling on the walls, and a ceiling light.
A patio with red Adirondack chairs and a table, surrounded by a pebble border.
A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
Hannibal

10/10 Exceptional

United States
Ernest
Super 8 by Wyndham Hannibal
A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.
A hotel room with two beds, a window with red curtains, an air conditioning unit, and two bedside lamps.
A coffee station with a coffee machine, cups, and a sign that says "RISE & SHINE."
A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
Hannibal

10/10 Exceptional

United States
Annette
Motel 6 Hannibal, MO

Frequently Asked Questions

What accommodations do travelers recommend in Louisiana?

Guests like River's Edge Motel and The Eagles Nest Inn.

Can I book refundable accommodations in Louisiana?

If you want the flexibility to change your travel plans to Louisiana, most hotels provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Louisiana be like during my trip?

The warmest months in Louisiana are usually July and August with an average temp of 74°F. January and February are the chilliest months when the average temp is 35°F. The rainiest months are May and April.

Why should I book my Louisiana accommodation with Hotels.com?

There are plenty of reasons to book your Louisiana travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.