Hotels in South San Francisco

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Aug 6 - Aug 7
Tomorrow
Aug 7 - Aug 8
This weekend
Aug 7 - Aug 9
Next weekend
Aug 14 - Aug 16

Top 5 hotels in South San Francisco at a glance

  1. DoubleTree by Hilton San Francisco South Airport Blvd — 4-star hotel in South San Francisco. Guest rating: 8.4/10 — Very Good.
  2. Best Western Plus Grosvenor Airport Hotel — 3-star hotel in South San Francisco. Guest rating: 8.4/10 — Very Good.
  3. Embassy Suites by Hilton San Francisco Airport Oyster Point — 3.5-star hotel in The East Side. Guest rating: 8.8/10 — Excellent.
  4. Sonesta Select San Francisco Airport Oyster Point Waterfront — 3-star hotel in Oyster Point. Guest rating: 8.8/10 — Excellent.
  5. La Quinta Inn & Suites by Wyndham San Francisco Airport N — 3-star hotel in Downtown South San Francisco. Guest rating: 8.2/10 — Very Good.

Where to stay in South San Francisco?

DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd
South San Francisco
$130
$153 total
includes taxes & fees
Aug 13 - Aug 14
DoubleTree by Hilton San Francisco South Airport Blvd

Best Western Plus Grosvenor Airport Hotel

Best Western Plus Grosvenor Airport Hotel
South San Francisco
$103
$120 total
includes taxes & fees
Aug 30 - Aug 31
Best Western Plus Grosvenor Airport Hotel

Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
The East Side
$147
$172 total
includes taxes & fees
Sep 7 - Sep 8
Embassy Suites by Hilton San Francisco Airport Oyster Point

Sonesta Select San Francisco Airport Oyster Point Waterfront

Sonesta Select San Francisco Airport Oyster Point Waterfront
Oyster Point
$117
$138 total
includes taxes & fees
Aug 16 - Aug 17
Sonesta Select San Francisco Airport Oyster Point Waterfront

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Downtown South San Francisco
$121
$141 total
includes taxes & fees
Sep 7 - Sep 8
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North
The East Side
$98
$115 total
includes taxes & fees
Aug 16 - Aug 17
Hilton Garden Inn San Francisco Arpt North

Home2 Suites by Hilton San Francisco Airport North

Home2 Suites by Hilton San Francisco Airport North
The East Side
$106
$124 total
includes taxes & fees
Sep 6 - Sep 7
Home2 Suites by Hilton San Francisco Airport North

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
The East Side
$127
$148 total
includes taxes & fees
Aug 14 - Aug 15
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Four Points by Sheraton Hotel & Suites San Francisco Airport

Four Points by Sheraton Hotel & Suites San Francisco Airport
South San Francisco
$95
$112 total
includes taxes & fees
Aug 16 - Aug 17
Four Points by Sheraton Hotel & Suites San Francisco Airport

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North
South San Francisco
$68
$81 total
includes taxes & fees
Aug 31 - Sep 1
Travelodge by Wyndham San Francisco Airport North

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
Oyster Point
$152
$180 total
includes taxes & fees
Aug 15 - Aug 16
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

Comfort Inn and Suites San Francisco Airport North

Comfort Inn and Suites San Francisco Airport North
The East Side
$103
$121 total
includes taxes & fees
Sep 4 - Sep 5
Comfort Inn and Suites San Francisco Airport North

Hampton Inn San Francisco Airport

Hampton Inn San Francisco Airport
The East Side
$110
$130 total
includes taxes & fees
Aug 23 - Aug 24
Hampton Inn San Francisco Airport

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Oyster Point
$123
$146 total
includes taxes & fees
Aug 23 - Aug 24
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Hotel Focus SFO

Hotel Focus SFO
The East Side
$98
$115 total
includes taxes & fees
Aug 16 - Aug 17
Hotel Focus SFO

Holiday Inn Express San Francisco-Airport North by IHG

Holiday Inn Express San Francisco-Airport North by IHG
South San Francisco
$110
$141 total
includes taxes & fees
Sep 6 - Sep 7
Holiday Inn Express San Francisco-Airport North by IHG

Hotel Nova SFO

Hotel Nova SFO
South San Francisco
$130
$152 total
includes taxes & fees
Aug 9 - Aug 10
Hotel Nova SFO

Larkspur Landing Extended Stay Suites South San Francisco

Larkspur Landing Extended Stay Suites South San Francisco
The East Side
$142
$166 total
includes taxes & fees
Aug 14 - Aug 15
Larkspur Landing Extended Stay Suites South San Francisco

Inn By The SFO

Inn By The SFO
Downtown South San Francisco
$89
$105 total
includes taxes & fees
Aug 11 - Aug 12
Inn By The SFO

Rodeway Inn South San Francisco Airport

Rodeway Inn South San Francisco Airport
South San Francisco
$87
$102 total
includes taxes & fees
Sep 7 - Sep 8
Rodeway Inn South San Francisco Airport
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Check out hotels with a pool in South San Francisco

Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
The East Side
$147
$172 total
includes taxes & fees
Sep 7 - Sep 8
Embassy Suites by Hilton San Francisco Airport Oyster Point

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Oyster Point
$123
$146 total
includes taxes & fees
Aug 23 - Aug 24
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Downtown South San Francisco
$121
$141 total
includes taxes & fees
Sep 7 - Sep 8
La Quinta Inn & Suites by Wyndham San Francisco Airport N

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
Oyster Point
$152
$180 total
includes taxes & fees
Aug 15 - Aug 16
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North
South San Francisco
$68
$81 total
includes taxes & fees
Aug 31 - Sep 1
Travelodge by Wyndham San Francisco Airport North
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You may also like pet-friendly hotels in South San Francisco

DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd
South San Francisco
$130
$153 total
includes taxes & fees
Aug 13 - Aug 14
DoubleTree by Hilton San Francisco South Airport Blvd

Hilton Garden Inn San Francisco Arpt North

Hilton Garden Inn San Francisco Arpt North
The East Side
$98
$115 total
includes taxes & fees
Aug 16 - Aug 17
Hilton Garden Inn San Francisco Arpt North

Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point
The East Side
$147
$172 total
includes taxes & fees
Sep 7 - Sep 8
Embassy Suites by Hilton San Francisco Airport Oyster Point

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Downtown South San Francisco
$121
$141 total
includes taxes & fees
Sep 7 - Sep 8
La Quinta Inn & Suites by Wyndham San Francisco Airport N

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area
The East Side
$127
$148 total
includes taxes & fees
Aug 14 - Aug 15
Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

Home2 Suites by Hilton San Francisco Airport North

Home2 Suites by Hilton San Francisco Airport North
The East Side
$106
$124 total
includes taxes & fees
Sep 6 - Sep 7
Home2 Suites by Hilton San Francisco Airport North

Four Points by Sheraton Hotel & Suites San Francisco Airport

Four Points by Sheraton Hotel & Suites San Francisco Airport
South San Francisco
$95
$112 total
includes taxes & fees
Aug 16 - Aug 17
Four Points by Sheraton Hotel & Suites San Francisco Airport

Hotel Focus SFO

Hotel Focus SFO
The East Side
$98
$115 total
includes taxes & fees
Aug 16 - Aug 17
Hotel Focus SFO

Hampton Inn San Francisco Airport

Hampton Inn San Francisco Airport
The East Side
$110
$130 total
includes taxes & fees
Aug 23 - Aug 24
Hampton Inn San Francisco Airport

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront

Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Oyster Point
$123
$146 total
includes taxes & fees
Aug 23 - Aug 24
Sonesta ES Suites San Francisco Airport Oyster Point Waterfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for hotels in South San Francisco are cheapest in January
Price trends for hotels in South San Francisco
Pricing is based on two traveler single night rates
View properties in August
Typical weather for South San Francisco
August
High 20°C / low 14°C. Sunny most days.
View properties in August
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Top neighborhoods in South San Francisco

Downtown South San Francisco

Downtown South San Francisco buzzes with a blend of biotech innovation and cultural diversity. Corporate towers and colorful murals tell the story of this unique business hub. You'll find authentic taquerias, dim sum houses, and Filipino eateries nestled between modern office campuses along Grand Avenue. The neighborhood comes alive during weekdays when professionals fill its plazas and restaurants. Getting around is a breeze with nearby BART and Caltrain stations connecting you to San Francisco proper and beyond. Business hotels cater mostly to corporate travelers with practical amenities. The area quiets down after work hours, offering a genuine glimpse into Bay Area life away from tourist crowds.

Oyster Point

Oyster Point balances sleek biotech campuses with stunning San Francisco Bay views. The waterfront promenade offers perfect spots for watching waves crash against the shore or catching a beautiful sunset. Modern plazas feature public art installations while walking paths showcase both cutting-edge architecture and natural bay ecosystems. Business travelers appreciate the corporate hotels with meeting facilities and convenient access to office buildings. Dining options cater primarily to weekday lunch crowds, with most establishments closing early evening. The area is best explored by car, though waterfront paths provide scenic strolling opportunities away from the corporate hustle.

The East Side

The East Side delivers authentic local life away from San Francisco's tourist traps. Catch Bay views from San Bruno Point Park or explore diverse family-owned restaurants along Grand Avenue serving up killer tacos and pho. This residential neighborhood mixes Hispanic and Asian influences that shine through local markets and casual eateries. Budget travelers appreciate the affordable motels and extended-stay options that cost way less than downtown San Francisco. Buses connect to BART and Caltrain, though having wheels helps. Most spots close early, so plan your food adventures accordingly.

Paradise Valley

Paradise Valley offers a peaceful retreat from San Francisco's bustle while keeping you close to the action. This quiet residential neighborhood in South San Francisco balances suburban calm with convenient access to nearby attractions. Take a stroll through San Bruno Point Park or venture to local spots like K1 Speed for some indoor racing fun. Budget-friendly accommodations make Paradise Valley an appealing base for Bay Area exploration. The neighborhood's proximity to San Francisco International Airport and major highways ensures easy connections throughout the region. With ample street parking and minimal crowds, you'll appreciate this low-key alternative to the city's more hectic districts.

Top landmarks in South San Francisco

San Bruno Point Park

7.8/10 (451 reviews)
If you like quiet time surrounded by flowers and greenery, hang out at San Bruno Point Park in The East Side. Our travelers also like this walkable area for its restaurants. Want to stretch your legs some more? Head to Bayfront Park and John McLaren Park, both nearby.
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South San Francisco Convention Center

7.8/10 (668 reviews)
South San Francisco Convention Center is worth a visit, located 0.5 mi (0.8 km) from central South San Francisco. Hotels.com travelers also say the area is full of friendly people and has lots of nice beaches. It's also full of great shops and restaurants, so you can spend the afternoon having a wander.
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San Francisco Baking Institute

7.6/10 (423 reviews)
If you'd like to get a taste of South San Francisco student life, check out San Francisco Baking Institute in The East Side. Let yourself be amazed at the art galleries in the area— your cultural tour starts here. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. South San Francisco has lots of other significant landmarks you might want to visit such as Golden Gate Bridge.
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See's Candies

8.0/10 (474 reviews)
See's Candies is 1.2 mi (2 km) from central South San Francisco, why not stop by during your stay. Hotels.com travelers also say the area is full of friendly people and has lots of nice beaches. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. If you have fun at See's Candies, you'll love Coastside Comics and K1 Speed San Francisco, both located nearby.
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South San Francisco Hillside Sign

If you're planning a bit of sightseeing head to South San Francisco Hillside Sign— just one of the monuments in Paradise Valley. South San Francisco has lots of other popular landmarks you might want to see such as Golden Gate Bridge.
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K1 Speed San Francisco

7.6/10 (330 reviews)
K1 Speed San Francisco is 1.1 mi (1.7 km) from central South San Francisco, why not stop by during your stay. Hotels.com travelers also say the area is full of friendly people and has lots of nice beaches. It's also full of great shops and restaurants, so you can spend the afternoon having a wander. If you have fun at K1 Speed San Francisco, you'll love See's Candies and Coastside Comics, both located nearby.
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Sign Hill Park

If you like quiet time surrounded by flowers and greenery, then make a stop at Sign Hill Park located 8.6 mi (13.8 km) from the center of San Francisco. Want to stretch your legs some more? Head to San Bruno Point Park and Bayfront Park, both nearby.
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Learn more about South San Francisco

Look beyond the iconic 'South San Francisco The Industrial City' sign crowning Sign Hill Park for a city with its own distinct identity. Grand Avenue serves up a global feast of family-run eateries where locals debate the merits of each dumpling house. San Bruno Mountain offers hiking trails with sweeping Bay views that explain why residents tolerate the fog. See's Candies factory tours satisfy sweet tooths, while K1 Speed delivers indoor racing thrills. The Convention Center hosts events that draw visitors who are surprised to discover this isn't simply San Francisco's southern neighborhood. Despite tripling in population since World War II, 'South City' maintains its working-class roots while embracing its role as a Peninsula destination in its own right.

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A large, modern bridge with a unique design against a clear blue sky.
Photo by Tonette Pineda✈⛵🚌🚉🚃🚅🚀

Check out reviews of South San Francisco hotels guests love

DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

8/10 Good
"I will say what I did not like! 1. The phone in the room was not working!! 2. The shower was not working properly. 3. We were 2 families and we requested 2 rooms close by… of course, they gave us rooms way, way apart. 4. We have stayed only 1 night, came late and left early so had no time to notice the good parts."
Mircea 1-night trip
Posted less than an hour ago
DoubleTree by Hilton Hotel Berkeley Marina
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

10/10 Excellent
"The views. The in room Keurig wouldn’t work unfortunately. It would be really nice to have hot coffee and hot water machines as a complimentary amenity in the lobby. Certainly wouldn’t be much of an expense for IHG."
cindy 3-night trip
Posted 1 hour ago
Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

10/10 Excellent
"Great breakfast and great location!"
Shengnan 2-night trip
Posted 4 hours ago
Hotel Riu Plaza Fisherman's Wharf
Embassy Suites by Hilton San Francisco Airport Oyster Point

Embassy Suites by Hilton San Francisco Airport Oyster Point

10/10 Excellent
"Justin the manager is amazing"
Kalonee 2-night trip
Posted 4 hours ago
Embassy Suites by Hilton San Francisco Airport Oyster Point
Chancellor Hotel on Union Square

Chancellor Hotel on Union Square

8/10 Good
"very coinvent to go to other places. CVS is just beside the hotel. Apple, cookies and drinks are available for guests."
Qihong 7-night trip
Posted 23 hours ago
Chancellor Hotel on Union Square
Travelodge by Wyndham San Francisco Airport North

Travelodge by Wyndham San Francisco Airport North

10/10 Excellent
"Had to ask many times for the maids to clean room and also I won'k 5am I ask for bed to made and clean room they did not to until yesterday then they try to clean when I have arrived from work"
Le Mont 5-night trip
Posted 1 day ago
Travelodge by Wyndham San Francisco Airport North

Frequently asked questions

What accommodations do travelers like in South San Francisco?
Can I book refundable accommodations in South San Francisco?
If you need the flexibility to change your travel plans to South San Francisco, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in South San Francisco if I want a vacation rental instead of a hotel?
If you're looking for a good alternative to a hotel, review our selection of 25 vacation homes. In addition, you can choose from 12 apartments.
What will the weather in South San Francisco be like during my visit?
The warmest months in South San Francisco are usually September and August with an average temp of 62°F. February and January are the chilliest months when the average temp is 53°F. The rainiest months are December and January.
Why should I book my South San Francisco accommodation with Hotels.com?
There are lots of reasons to book your South San Francisco trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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