Photo by Jennifer Radman

Hotels in Des Peres

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Check prices for these dates

Tonight
Dec 30 - Dec 31
Tomorrow
Dec 31 - Jan 1
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Where to stay in Des Peres?

Lobby
Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport
2.5 star property
9.4 out of 10, Exceptional, (2775)
  • cleanliness
    Comfortable airport haven with free shuttle and spacious amenities awaits.
The price is $90
$106 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Pear Tree Inn St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Budget hotels in Des Peres and vicinity

Meeting facility
Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
Hazelwood
8.4 out of 10, Very Good, (1649)
The price is $58
$71 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Motel 6 Hazelwood, MO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top landmarks in Des Peres

Museum of Transportation

Museum of Transportation is 2.5 mi (4 km) from central Des Peres, why not stop by during your stay. If you want to experience more of the culture Des Peres has to offer, head to Magic House - St. Louis Children's Museum, SSM Health St. Clare Hospital - Fenton, and Missouri Baptist Medical Center.
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Sugar Creek Park

Sugar Creek Park is worth a visit, located 1.8 mi (2.9 km) from central Des Peres. Our travelers also like the museums in the area— your cultural tour starts here.
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Learn more about Des Peres

Around Des Peres are top attractions including St. Louis Union Station and Busch Stadium.

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Osage Beach Landmark Buildings in the Historic District on the Main Street near the Lake of the Ozarks in Camden and Miller Counties in Missouri, USA

Check out reviews of Des Peres hotels guests love

21C Museum Hotel St Louis

21C Museum Hotel St Louis

10/10 Excellent
"clean room hotel"
Stephen 1-night trip
Posted 18 hours ago
21C Museum Hotel St Louis

Frequently asked questions

What hotels do travelers like in Des Peres?
Guests like Clayton Plaza Hotel & Extended Stay, Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and Best Western St. Louis-Kirkwood Route 66.
Can I book refundable hotels in Des Peres?
If you need the flexibility to change your plans to Des Peres, most accommodations offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Des Peres be like during my trip?
The warmest months in Des Peres are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 37°F. The rainiest months are May and April.
Why should I book my Des Peres accommodation with Hotels.com?
There are plenty of reasons to book your Des Peres travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.