
Photo by Southernmost Illinois Tourism Bureau
Hotels in Murphysboro
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Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (512)
9.4/10
Exceptional
(512)
The price is $97
$97
$108 total
includes taxes & fees
Dec 26 - Dec 27




University Inn of Carbondale
University Inn of Carbondale
2.5 star property
Carbondale
6.0 out of 10, (329)
6.0/10
(329)
The price is $55
$55
$63 total
includes taxes & fees
Dec 26 - Dec 27




Super 8 by Wyndham Carbondale
Super 8 by Wyndham Carbondale
2.0 star property
Carbondale
7.4 out of 10, Good, (1000)
7.4/10
Good
(1000)
The price is $55
$55
$63 total
includes taxes & fees
Dec 29 - Dec 30




Home2 Suites by Hilton Carbondale
Home2 Suites by Hilton Carbondale
3.0 star property
Carbondale
8.8 out of 10, Excellent, (514)
8.8/10
Excellent
(514)
The price is $106
$106
$122 total
includes taxes & fees
Jan 11 - Jan 12, 2026




Best Western Saluki Inn
Best Western Saluki Inn
2.5 star property
Carbondale
8.0 out of 10, Very Good, (1001)
8.0/10
Very Good
(1001)
The price is $81
$81
$95 total
includes taxes & fees
Jan 7 - Jan 8, 2026




Quality Inn Carbondale University area
Quality Inn Carbondale University area
2.5 star property
Carbondale
5.8 out of 10, (838)
5.8/10
(838)
The price is $54
$54
$62 total
includes taxes & fees
Dec 30 - Dec 31




Comfort Inn & Suites Carbondale University Area
Comfort Inn & Suites Carbondale University Area
2.5 star property
Carbondale
7.6 out of 10, Good, (519)
7.6/10
Good
(519)
The price is $78
$78
$90 total
includes taxes & fees
Jan 7 - Jan 8, 2026




Hampton Inn Carbondale
Hampton Inn Carbondale
2.5 star property
Carbondale
8.4 out of 10, Very Good, (615)
8.4/10
Very Good
(615)
The price is $114
$114
$131 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Holiday Inn Carbondale-Conference Center by IHG
Holiday Inn Carbondale-Conference Center by IHG
3.0 star property
Carbondale
8.8 out of 10, Excellent, (645)
8.8/10
Excellent
(645)
The price is $114
$114
$131 total
includes taxes & fees
Jan 22 - Jan 23, 2026




Walker's Bluff Casino Resort
Walker's Bluff Casino Resort
4.5 star property
Carterville
9.4 out of 10, Exceptional, (389)
9.4/10
Exceptional
(389)
The price is $125
$125
$139 total
includes taxes & fees
Dec 28 - Dec 29




Fairgrounds Inn
Fairgrounds Inn
2.0 star property
Du Quoin
7.6 out of 10, Good, (380)
7.6/10
Good
(380)
The price is $110
$110
$122 total
includes taxes & fees
Jan 3 - Jan 4, 2026




Motel 6 Marion, IL
Motel 6 Marion, IL
2.0 star property
Marion
7.2 out of 10, Good, (613)
7.2/10
Good
(613)
The price is $65
$65
$72 total
includes taxes & fees
Dec 26 - Dec 27




Super 8 by Wyndham Du Quoin
Super 8 by Wyndham Du Quoin
2.0 star property
Du Quoin
6.8 out of 10, (373)
6.8/10
(373)
The price is $85
$85
$94 total
includes taxes & fees
Dec 26 - Dec 27




Comfort Inn & Suites Marion I-57
Comfort Inn & Suites Marion I-57
2.5 star property
Marion
9.4 out of 10, Exceptional, (1002)
9.4/10
Exceptional
(1002)
The price is $108
$108
$130 total
includes taxes & fees
Jan 7 - Jan 8, 2026




Drury Inn & Suites Marion
Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1006)
9.4/10
Exceptional
(1006)
The price is $65
$65
$78 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Country Inn & Suites by Radisson, Marion, IL
Country Inn & Suites by Radisson, Marion, IL
2.5 star property
Marion
8.6 out of 10, Excellent, (1001)
8.6/10
Excellent
(1001)
The price is $97
$97
$116 total
includes taxes & fees
Jan 14 - Jan 15, 2026




Fairfield Inn and Suites by Marriott Marion
Fairfield Inn and Suites by Marriott Marion
2.5 star property
Marion
8.4 out of 10, Very Good, (361)
8.4/10
Very Good
(361)
The price is $93
$93
$112 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Holiday Inn Express Hotel & Suites Marion Northeast by IHG
Holiday Inn Express Hotel & Suites Marion Northeast by IHG
2.5 star property
Marion
9.0 out of 10, Wonderful, (929)
9.0/10
Wonderful
(929)
The price is $104
$104
$125 total
includes taxes & fees
Jan 3 - Jan 4, 2026




Baymont by Wyndham Marion
Baymont by Wyndham Marion
2.5 star property
Marion
8.4 out of 10, Very Good, (1078)
8.4/10
Very Good
(1078)
The price is $74
$74
$89 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Quality Inn & Suites Marion
Quality Inn & Suites Marion
2.5 star property
Marion
7.4 out of 10, Good, (1001)
7.4/10
Good
(1001)
The price is $59
$59
$70 total
includes taxes & fees
Jan 22 - Jan 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Murphysboro
Pet friendly
Family friendly
trending_down When is the best time to visit Murphysboro?
When is the best time to visit Murphysboro?Our prices for hotels in Murphysboro are cheapest in January
When is the best time to visit Murphysboro?
When is the best time to visit Murphysboro?
Our prices for hotels in Murphysboro are cheapest in January
Price trends for hotels in Murphysboro
Pricing is based on two traveler single night rates
Currently viewing crowd sizes and weather for December.trending_flat Moderate crowds
Typical weather for Murphysboro
December
High 8°C / low 0°C. Partly sunny.
View properties in December 8°
December, Moderate crowds, average high temperature 8 degrees Celsius, average low temperature 0 degrees Celsius. Partly sunny.
0°
5°
January, Low crowds, average high temperature 5 degrees Celsius, average low temperature -3 degrees Celsius. Partly sunny.
-3°
7°
February, Low crowds, average high temperature 7 degrees Celsius, average low temperature -2 degrees Celsius. Partly sunny.
-2°
13°
March, High crowds, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Partly sunny.
4°
19°
April, Moderate crowds, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
9°
24°
May, Moderate crowds, average high temperature 24 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
15°
30°
June, High crowds, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
31°
July, High crowds, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
30°
August, High crowds, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
27°
September, Low crowds, average high temperature 27 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
20°
October, Low crowds, average high temperature 20 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
11°
13°
November, Moderate crowds, average high temperature 13 degrees Celsius, average low temperature 4 degrees Celsius. Partly sunny.
4°
Monthly weather averages (˚C)
Top landmarks in Murphysboro
Hickory Ridge Public Golf Center
3.1/5 (7 reviews)
You might want to play some rounds at Hickory Ridge Public Golf Center, located 4.2 mi (6.8 km) from central Murphysboro. If Hickory Ridge Public Golf Center doesn't quite scratch your golfing itch, Crab Orchard Golf Club and Stone Creek Golf Club and Resort are all just a short drive away.
Learn more about Murphysboro
Murphysboro is well-known for its attractions such as Hickory Ridge Public Golf Center and Kinkaid Village Marina.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
Check out reviews of Murphysboro hotels guests love

Quality Inn And Suites
10/10 Excellent
"GRE "

Best Western Saluki Inn
10/10 Excellent
"Clean room and a very helpful staff. We enjoyed our stay."

Super 8 by Wyndham Carbondale
10/10 Excellent
"Absolutely amazing staff , very professional and friendly and helpful. Clean rooms and good breakfast. Clean environment."

Baymont by Wyndham Marion
10/10 Excellent
"Great room! "

Drury Inn & Suites Marion
10/10 Excellent
"Clean room, good food"

Best Western Marion Hotel
10/10 Excellent
"The room was nice and warm!"

Motel 6 Marion, IL
10/10 Excellent
"Clean room, daily housekeeping, comfy beds, everything worked great. Great staff."

Comfort Inn & Suites Carbondale University Area
10/10 Excellent
"Cold"

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
10/10 Excellent
"Everything was good
"
Frequently asked questions
What accommodations do travelers like in Murphysboro?
Can I book a refundable accommodation in Murphysboro?
If you're looking for the flexibility to change your travel plans to Murphysboro, most accommodations offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Where should I stay in Murphysboro if I'm looking for an affordable accommodation?
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG is an accommodation you might want to consider that'll save you money.
Where can I stay in Murphysboro if I want a vacation home instead of a hotel?
If you're looking for a good alternative to a hotel, look over our selection of 14 vacation homes. You can also book one of the 6 cabins for your stay.
What will the weather in Murphysboro be like during my vacation?
July and August are typically the warmest months in Murphysboro when the average temp is 76°F. January and February are the coldest months when the average temperature is 39°F. April and March are the months with the most rain.
Why should I book my Murphysboro hotel with Hotels.com?
There are plenty of reasons to book your Murphysboro travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.