Hotels in Doniphan

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Top 5 hotels in Doniphan at a glance

Hampton Inn Poplar Bluff — 2.5-star hotel in Poplar Bluff. Guest rating: 9.4/10 — Exceptional.
Drury Inn & Suites Poplar Bluff — 3-star hotel in Poplar Bluff. Guest rating: 9.4/10 — Exceptional.
Fairfield Inn & Suites by Marriott Poplar Bluff — 3-star hotel in Poplar Bluff. Guest rating: 9.4/10 — Exceptional.
Holiday Inn Poplar Bluff by IHG — 3-star hotel in Poplar Bluff. Guest rating: 8.8/10 — Excellent.
Days Inn & Suites by Wyndham Pocahontas — 2.5-star hotel in Pocahontas. Guest rating: 7.8/10 — Good.

Where to stay in Doniphan?

A spacious dining area with multiple tables and chairs, a flat-screen TV mounted on the wall, and large windows providing natural light.

Hampton Inn Poplar Bluff

Poplar Bluff

$93

$105 total

includes taxes & fees

Sep 13 - Sep 14

A spacious lobby with a reception desk, seating area, and large windows.

A hotel room with a bed, a desk, a chair, a sofa, and a TV.

A spacious conference room with brick walls, multiple tables and chairs, a large window, and a mounted TV.

A spacious lobby with a high ceiling, a mezzanine level, and a seating area with a sofa and chairs.

Drury Inn & Suites Poplar Bluff

Poplar Bluff

$102

$115 total

includes taxes & fees

Sep 6 - Sep 7

A modern lounge area with a stone fireplace, blue seating, a round coffee table, and a large window offering a view.

A reception area with a wooden counter, a coffee machine, and a display of pastries.

A reception desk with a bicycle light, potted plants, and a 'Connect & Print' sign.

An outdoor patio with a table and chairs, a large umbrella, and a glass door leading to an interior space.

Fairfield Inn & Suites by Marriott Poplar Bluff

Poplar Bluff

$101

$114 total

includes taxes & fees

Sep 7 - Sep 8

A Holiday Inn hotel with a covered entrance, multiple flags, and a brick facade.

An indoor swimming pool with clear water, marked depth lines, and lounge chairs along the side.

A hotel lobby with a reception desk, seating area, and a television screen.

A bathroom with a shower, a sink, and a mirror.

Holiday Inn Poplar Bluff by IHG

Poplar Bluff

$88

$99 total

includes taxes & fees

Sep 13 - Sep 14

A grand staircase with a chandelier at the top, leading to a well-lit interior space.

A Days Inn & Suites hotel with a modern design, featuring a large parking lot and well-maintained landscaping.

A hotel dining area with round tables and chairs, a patterned carpet, and a chandelier.

A hotel room with a bed, a sitting area with a chair, a desk, a lamp, a large mirror, and a bathtub.

Days Inn & Suites by Wyndham Pocahontas

Pocahontas

$89

$100 total

includes taxes & fees

Sep 6 - Sep 7

A modern kitchen with a coffee machine, a sink, and a counter. There are four chairs and a table in the dining area.

A motel with a prominent '66' sign, large windows, and a flat roof.

A hotel reception area with a modern design, featuring a reception desk, a glass door, and a wall with framed pictures and a large number '6' sign.

A compact kitchen with a dark wooden desk, a black refrigerator, a microwave, and a coffee maker.

Motel 6 Poplar Bluff, MO

Poplar Bluff

$79

$88 total

includes taxes & fees

Sep 2 - Sep 3

A hotel lobby with a reception desk, a blue sofa, a fireplace, and a television.

A hotel with a covered entrance, multiple windows, and a yellow facade.

A hotel room with a bed, two armchairs, a sofa, a small table, a TV, a ceiling fan, and a window with curtains.

A hotel room with a bed, a sofa, a small table, and a painting on the wall.

Comfort Inn Poplar Bluff North

Poplar Bluff

$81

$91 total

includes taxes & fees

Sep 20 - Sep 21

A bedroom with a bed, a desk, and a chair. There is a window with curtains, a radiator, and a wall-mounted shelf with a towel.

A group of people sitting at picnic tables outdoors, surrounded by trees and a fenced area.

A motel with a parking lot, a covered picnic area, and a row of rooms with individual entrances.

A playground with slides and swings, a mailbox, and a caution sign.

Current River Inn

Van Buren

$109

$118 total

includes taxes & fees

Sep 1 - Sep 2

A hotel room with a bed, two bedside lamps, a framed picture of a building, and a nightstand with a phone.

A two-story motel with a covered parking area and a bench outside.

A lobby with a reception desk, a Coca-Cola vending machine, a snack vending machine, and a seating area with a round table.

A self-service breakfast area with a refrigerated drink cooler, a coffee machine, and various food items on the counter.

Super 8 by Wyndham Poplar Bluff Missouri

Poplar Bluff

$70

$79 total

includes taxes & fees

Sep 21 - Sep 22

A rustic cabin with a metal roof, surrounded by a wooden deck and picnic tables, set in a forested area.

A bedroom with a wooden bed, a bench, and a window.

A wooden deck with a railing leading to a building with a metal roof and a brown door.

Lake Wappapello

Williamsville

$100

$105 total

includes taxes & fees

Sep 1 - Sep 2

A kitchen with granite countertops, wooden cabinets, a stainless steel sink, and a wooden chair.

A single-story house with a front porch, a small attached garage, and a pathway leading to the entrance.

A kitchen with wooden cabinets, a refrigerator, a stove, and a sink.

A porch with a door, two chairs, and potted plants.

Home Near Eleven Point River & Nat'l Forest!

Alton

$116

$206 total

includes taxes & fees

Sep 4 - Sep 5

View all properties

Go beyond your typical stay in Doniphan

Pet friendly

Pool

Cottage

Top landmarks in Doniphan

Deer Leap Recreation Area

Deer Leap Recreation Area is 5.1 mi (8.1 km) from central Doniphan, why not stop by during your stay. Want to stretch your legs some more? Head to Float Camp Recreation Area, located nearby.

See properties

Float Camp Recreation Area

Float Camp Recreation Area is 4.3 mi (7 km) from central Doniphan, why not stop by during your stay. Want to stretch your legs some more? Head to Deer Leap Recreation Area, located nearby.

See properties

Southeast Health Center Of Ripley County

Southeast Health Center Of Ripley County is worth a visit when in central Doniphan.

See properties

Learn more about Doniphan

Doniphan is well-known for its attractions such as Current River and Ozark National Scenic Riverways. The city has something for everyone including sights like Mark Twain National Forest and Eleven Point State Park within a small-town setting.

See all hotels in Doniphan

A clear pond surrounded by trees with autumn leaves.

Check out reviews of Doniphan hotels guests love

Holiday Inn Poplar Bluff by IHG

10/10 Excellent

"It was great"

Drury Inn & Suites Poplar Bluff

10/10 Excellent

"Good price, clean rooms and 3 free drinks and snacks. What more could you want."

Days Inn & Suites by Wyndham Pocahontas

8/10 Good

"bed was hard and the springs were poking up"

Frequently asked questions

Can I book refundable hotels in Doniphan?

If you're looking for the flexibility to change your travel plans to Doniphan, most properties offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where can I stay in Doniphan if I want a vacation home instead of a traditional hotel?

You'll find 8 vacation homes on our site. You can also book one of the 10 cabins for your stay.

What will the weather in Doniphan be like during my trip?

The warmest months in Doniphan are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and May.

Why should I book my Doniphan hotel through Hotels.com?

There are plenty of reasons to book your Doniphan travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring

More ways to book

Book Hotels in Doniphan on Hotels.com