Hotels in Columbus

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Check prices for these dates

Tonight
Nov 6 - Nov 7
Tomorrow
Nov 7 - Nov 8
This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Where to stay in Columbus?

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

1. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, Good, (684 reviews)
This Charleston motel offers complimentary WiFi, parking, and on-the-go breakfast daily. Located with convenient interstate access to Cape Girardeau, guests consistently praise the helpful staff. The comfortable accommodations provide a practical base for exploring southeastern Missouri.
The price is $59
$66 total
includes taxes & fees
Dec 1 - Dec 2
Super 8 by Wyndham Charleston/Sikeston East MO
A building with a fountain and flower beds in front.

2. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, Good, (443 reviews)
The price is $66
$74 total
includes taxes & fees
Nov 8 - Nov 9
The Riverstone Hotel Charleston-Sikeston
A hotel lobby with a reception desk, seating area, and a large window.

3. Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, Good, (296 reviews)
Set off I-57 in Cairo, this welcoming hotel provides complimentary full breakfast and self parking. Explore nearby Fort Defiance State Park or take a short drive to Ballard Wildlife Management Area while enjoying free WiFi throughout your stay.
The price is $69
$76 total
includes taxes & fees
Nov 15 - Nov 16
Quality Inn Cairo I-57
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

4. Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, Good, (107 reviews)
Active travelers will appreciate the health club at this comfortable Charleston motel. Free WiFi keeps you connected, while complimentary parking saves you money. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.
The price is $66
$74 total
includes taxes & fees
Nov 7 - Nov 8
Eagle Inn Charleston
A modern kitchen with white cabinetry, stainless steel appliances, and a window with a view of greenery.

5. Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is $149
$290 total
includes taxes & fees
Nov 8 - Nov 9
Quiet Country Stay: Modern Home Near Paducah
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Go beyond your typical stay in Columbus

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Top landmarks in Columbus

Columbus-Belmont State Park

7.4/10 (23 reviews)
If you're planning a bit of sightseeing during your trip, head to Columbus-Belmont State Park— just one of the monuments in central Columbus.
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Frequently Asked Questions

Can I book a refundable hotel in Columbus?

If you're looking for the flexibility to change your plans to Columbus, most accommodations offer refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Columbus be like during my visit?

The warmest months in Columbus are usually July and August with an average temp of 77°F. January and February are the chilliest months when the average temp is 42°F. The rainiest months are April and March.

Why should I book my Columbus accommodation with Hotels.com?

There are plenty of reasons to book your Columbus travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.