If you're looking to discover somewhere new, look no further than Cayce. Whether you're planning to stay for a night or for the week, the area around Cayce has accommodations to fit every need. Search for hotels in Cayce with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Cayce hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Cayce hotel deals are here with our lowest price guarantee.
Hotels in Cayce
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Where to stay in Cayce?

Courtyard by Marriott Columbia Cayce
Courtyard by Marriott Columbia Cayce
9.0 out of 10, Wonderful, (630)
The price is $114
$127 total
includes taxes & fees
Jul 27 - Jul 28

Country Inn & Suites by Radisson, Columbia Airport, SC
Country Inn & Suites by Radisson, Columbia Airport, SC
8.2 out of 10, Very Good, (1003)
The price is $103
$114 total
includes taxes & fees
Jul 27 - Jul 28

Masters Inn Columbia I-26
Masters Inn Columbia I-26
5.2 out of 10, (350)
The price is $60
$67 total
includes taxes & fees
Jul 31 - Aug 1

Motel 6 West Columbia, SC - Airport
Motel 6 West Columbia, SC - Airport
7.6 out of 10, Good, (322)
The price is $59
$64 total
includes taxes & fees
Jul 19 - Jul 20

Adorable on Taylor Both Units
Adorable on Taylor Both Units
The price is $293
$566 total
includes taxes & fees
Jul 20 - Jul 21

Sleep Inn Airport
Sleep Inn Airport
7.8 out of 10, Good, (782)
The price is $81
$94 total
includes taxes & fees
Jul 20 - Jul 21

Days Inn & Suites by Wyndham Columbia Airport
Days Inn & Suites by Wyndham Columbia Airport
5.8 out of 10, (732)
The price is $67
$73 total
includes taxes & fees
Jul 17 - Jul 18

Red Roof Inn Columbia, SC Airport
Red Roof Inn Columbia, SC Airport
6.0 out of 10, (450)
The price is $74
$80 total
includes taxes & fees
Jul 16 - Jul 17

Gallus Stadium Park Inn, Ascend Hotel Collection
Gallus Stadium Park Inn, Ascend Hotel Collection
6.6 out of 10, (989)
The price is $67
$75 total
includes taxes & fees
Jul 15 - Jul 16

Tru By Hilton Columbia Downtown
Tru By Hilton Columbia Downtown
9.2 out of 10, Wonderful, (174)
The price is $101
$113 total
includes taxes & fees
Jul 27 - Jul 28

Homewood Suites By Hilton Columbia Downtown
Homewood Suites By Hilton Columbia Downtown
9.0 out of 10, Wonderful, (28)
The price is $127
$142 total
includes taxes & fees
Jul 27 - Jul 28

Columbia Duet Unit B
Columbia Duet Unit B
The price is $273
$544 total
includes taxes & fees
Jul 20 - Jul 21

Courtyard by Marriott Columbia Downtown at USC
Courtyard by Marriott Columbia Downtown at USC
8.8 out of 10, Excellent, (1002)
The price is $127
$142 total
includes taxes & fees
Jul 25 - Jul 26

SpringHill Suites by Marriott Columbia Downtown/The Vista
SpringHill Suites by Marriott Columbia Downtown/The Vista
8.8 out of 10, Excellent, (1002)
The price is $116
$130 total
includes taxes & fees
Jul 25 - Jul 26

Quality Inn Columbia Airport
Quality Inn Columbia Airport
6.6 out of 10, (942)
The price is $65
$70 total
includes taxes & fees
Aug 3 - Aug 4

Hilton Columbia Center
Hilton Columbia Center
9.0 out of 10, Wonderful, (1004)
The price is $111
$127 total
includes taxes & fees
Jul 26 - Jul 27

Hyatt Place Columbia/Downtown/The Vista
Hyatt Place Columbia/Downtown/The Vista
8.8 out of 10, Excellent, (1013)
The price is $118
$132 total
includes taxes & fees
Jul 25 - Jul 26

Aloft Columbia Downtown
Aloft Columbia Downtown
9.0 out of 10, Wonderful, (751)
The price is $111
$124 total
includes taxes & fees
Jul 26 - Jul 27

Fairfield Inn & Suites by Marriott Columbia Downtown
Fairfield Inn & Suites by Marriott Columbia Downtown
8.6 out of 10, Excellent, (1007)
The price is $98
$110 total
includes taxes & fees
Jul 18 - Jul 19

Cambria Hotel Columbia Downtown The Vista
Cambria Hotel Columbia Downtown The Vista
9.4 out of 10, Exceptional, (1052)
The price is $122
$140 total
includes taxes & fees
Jul 20 - Jul 21
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Cayce
Pet friendly
Top landmarks in Cayce
Cayce Historical Museum
You can spend time browsing the exhibits at Cayce Historical Museum during your trip to Cayce. You can attend a sporting event while in the area.
Learn more about Cayce
Kayak along the Congaree River, spotting wildlife and enjoying the lush riverbanks. Explore the Cayce Historical Museum to uncover fascinating local history and Native American artifacts.
Check out reviews of Cayce hotels guests love

Tru By Hilton Columbia Downtown
10/10 Excellent
Frequently asked questions
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- Hotels near Benedict College
- Hotels near Congaree Creek Heritage Preserve
- Hotels near Cayce Historical Museum
- Hotels near Fort Jackson
- Hotels near University of South Carolina
- Hotels near Williams Brice Stadium
- Hotels near Riverbanks Zoo and Garden
- Hotels near Colonial Life Arena
- Hotels near Columbia Metropolitan Convention Center
- Hotels near Village at Sandhill Mall
- Hotels near Township Auditorium
- Hotels near South Carolina State Fairgrounds
- Hotels near Columbiana Centre
- Hotels near Hilton Field
- Hotels near Lexington Medical Center
- Hotels near South Carolina State House
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- Hampton Inn Columbia I-26/Harbison Blvd.
- Courtyard by Marriott Columbia Downtown at USC
- Hilton Garden Inn Columbia Downtown, SC
- Hampton Inn & Suites Columbia Killian Road
- Holiday Inn Express & Suites Columbia-Fort Jackson by IHG
- Gallus Stadium Park Inn, Ascend Hotel Collection
- Springhill Suites by Marriott Columbia near Fort Jackson
- Hilton Columbia Center
- Sleep Inn Near Ft Jackson
- Marriott Columbia
- Holiday Inn Columbia - Downtown by IHG
- Hampton Inn & Suites Columbia/Southeast-Ft. Jackson
- Motel 6 West Columbia, SC - Airport
- Holiday Inn Express Columbia - Two Notch by IHG
- Hampton Inn Columbia-I-26 Airport
- Hilton Garden Inn Columbia Airport
- Fairfield Inn & Suites by Marriott Columbia Downtown
- Sheraton Columbia Downtown Hotel
- Aloft Columbia Harbison
- Lexington Inn and Suites
- SpringHill Suites by Marriott Columbia Downtown/The Vista
- Moxy Columbia Downtown
- Fairfield by Marriott Inn & Suites Columbia Harbison
- Best Western Plus Lexington Inn
- Quality Inn Fort Jackson
- Fairfield Inn and Suites by Marriott Columbia
- Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHG
- Courtyard by Marriott Columbia Northeast/Fort Jackson Area
- Baymont by Wyndham Columbia Northwest
- WoodSpring Suites Columbia Fort Jackson
- Home2 Suites by Hilton Columbia Downtown
- Home2 Suites by Hilton Columbia Southeast Fort Jackson
- Residence Inn by Marriott Columbia Northwest/Harbison
- Doubletree by Hilton Columbia, SC
- Comfort Inn Blythewood - North Columbia
- Quality Inn & Suites Columbia Harbison
- TownePlace Suites by Marriott Columbia Southeast/Ft Jackson
- Wingate by Wyndham Columbia / Lexington
- Tru by Hilton Harbison Columbia
- Holiday Inn Express & Suites Lexington by IHG
- Hotel Trundle
- Aloft Columbia Downtown
- Clarion Inn Columbia Airport
- Country Inn & Suites by Radisson, Columbia at Harbison, SC
- Homewood Suites By Hilton Columbia Downtown
- Residence Inn by Marriott Columbia Northeast/Fort Jackson Area
- Staybridge Suites Columbia by IHG
- Home2 Suites by Hilton Columbia Harbison
- Hawthorn Extended Stay By Wyndham Columbia / Ft. Jackson
- Wingate by Wyndham Columbia/Fort Jackson
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