Hotels in Affton

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Check prices for these dates

Tonight
Nov 2 - Nov 3
Tomorrow
Nov 3 - Nov 4
This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Where to stay in Affton?

A spacious lobby with a high ceiling, a central chandelier, and a patterned floor.

1. River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,835 reviews)
Immerse yourself in gaming excitement at this hotel with an upscale steakhouse, 24-hour fitness center, and complimentary parking. Located near Jefferson Barracks Historic Park, guests consistently praise the attentive staff and immaculate accommodations.
The price is $103
$135 total
includes taxes & fees
Dec 2 - Dec 3
River City Casino & Hotel
A spacious lobby with multiple seating areas, a central coffee table, and artwork on the walls.

2. Best Western St. Louis-Kirkwood Route 66

Best Western St. Louis-Kirkwood Route 66
3.5 star property
Kirkwood
8.2 out of 10, Very good, (1,570 reviews)
Just off Route 66, this Kirkwood hotel offers a seasonal outdoor pool and children's splash area. Enjoy free breakfast before exploring nearby Forest Park or dining at the on-site Chili's. Comfortable beds and helpful staff make for a peaceful, convenient stay.
The price is $96
$113 total
includes taxes & fees
Nov 3 - Nov 4
Best Western St. Louis-Kirkwood Route 66
A swimming pool with a metal ladder, surrounded by chairs and large windows offering a view of the sunset.

3. La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66
3.0 star property
St. Louis
8.4 out of 10, Very good, (1,005 reviews)
Wake up to complimentary breakfast before taking a morning dip in the indoor pool at this art deco hotel. Located within 15 minutes of Forest Park and St. Louis Zoo, with Kirkwood Station just 4 minutes away by car.
The price is $99
$116 total
includes taxes & fees
Nov 29 - Nov 30
La Quinta Inn & Suites by Wyndham St Louis Route 66
A spacious lobby with a high ceiling, modern lighting fixtures, a seating area with sofas and chairs, and a bar area with stools.

4. Hampton Inn & Suites St. Louis/South I-55

Hampton Inn & Suites St. Louis/South I-55
2.5 star property
St. Louis
9.6 out of 10, Exceptional, (1,000 reviews)
Located just off I-55, this hotel offers complimentary WiFi and parking near Kennedy Rink. After a workout in the fitness center, retreat to comfortable rooms. The helpful staff ensures a pleasant stay, with Kirkwood Station only 14 minutes away.
The price is $110
$126 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn & Suites St. Louis/South I-55
A hotel room with a minibar, a shoe rack, a coat rack, and a TV.

5. Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG
2.5 star property
St. Louis
9.6 out of 10, Exceptional, (1,001 reviews)
Experience comfort at this business-friendly hotel with an indoor pool and 24-hour fitness center. Enjoy complimentary breakfast, WiFi, and parking while exploring nearby Suson Park. Guests rave about the helpful staff and convenient South I-55 location.
The price is $109
$125 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn Express & Suites St. Louis South - I-55 by IHG
A modern lobby with a grey sofa, two armchairs, a round table, and a chandelier. There are two posters on the wall and a reception desk in the background.

6. Holiday Inn St Louis SW - Route 66 by IHG

Holiday Inn St Louis SW - Route 66 by IHG
3.0 star property
St. Louis
9.2 out of 10, Wonderful, (600 reviews)
The price is $114
$136 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn St Louis SW - Route 66 by IHG
A digital display with three screens showing hotel information.

7. SpringHill Suites St. Louis Brentwood

SpringHill Suites St. Louis Brentwood
3.0 star property
Brentwood
9.0 out of 10, Wonderful, (1,003 reviews)
Moments from Brentwood Station, this hotel offers a complimentary breakfast to fuel your Forest Park adventures. After visiting the nearby St. Louis Zoo, recharge in the 24-hour fitness center before exploring Union Station's dining scene.
The price is $125
$148 total
includes taxes & fees
Nov 20 - Nov 21
SpringHill Suites St. Louis Brentwood
A hotel room with two beds, a chair, a desk, and a large window.

8. Forest Park Hotel by MDR

Forest Park Hotel by MDR
3.0 star property
The Hill
7.4 out of 10, Good, (1,690 reviews)
Discover comfort just minutes from Forest Park and Barnes Jewish Hospital. This hotel offers free WiFi and parking, with hiking trails nearby. St. Louis Union Station and Gateway Arch are a short drive away, while helpful staff ensure a pleasant experience.
The price is $73
$91 total
includes taxes & fees
Dec 2 - Dec 3
Forest Park Hotel by MDR
A modern living room with a sofa set, a coffee table, and a TV mounted on the wall.

9. Fairfield Inn & Suites by Marriott St. Louis South

Fairfield Inn & Suites by Marriott St. Louis South
3.0 star property
St. Louis
9.6 out of 10, Exceptional, (396 reviews)
This St. Louis South hotel offers an indoor pool and 24-hour fitness center, with free breakfast, WiFi, and parking. Guests rave about the helpful staff and clean rooms, with Suson Park and Sylvan Springs County Park nearby.
The price is $130
$149 total
includes taxes & fees
Nov 15 - Nov 16
Fairfield Inn & Suites by Marriott St. Louis South
A hotel room with two beds, a desk, and a window with a view of trees.

10. Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.0 out of 10, Wonderful, (472 reviews)
The price is $93
$107 total
includes taxes & fees
Nov 8 - Nov 9
Best Western Plus Fenton
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

11. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,001 reviews)
Escape to this Brentwood hotel with indoor and outdoor pools just a short walk from public transit. Explore nearby St. Louis Zoo and Forest Park or enjoy the complimentary breakfast. Free WiFi and parking enhance your stay.
The price is $128
$152 total
includes taxes & fees
Nov 22 - Nov 23
Drury Plaza Hotel St. Louis Brentwood
A modern living area with a sofa, armchairs, a coffee table, and a kitchen in the background.

12. Best Western St. Louis Inn

Best Western St. Louis Inn
2.5 star property
St. Louis
8.4 out of 10, Very good, (1,200 reviews)
Experience tranquility at this hotel just a short drive from Mississippi River. The indoor pool offers morning swims, while the fitness center keeps routines on track. Enjoy complimentary breakfast and parking before exploring nearby BounceU and Kennedy Rink.
The price is $71
$82 total
includes taxes & fees
Nov 11 - Nov 12
Best Western St. Louis Inn
A modern interior with a high ceiling, large windows, and a brick wall. There are orange chairs and a green sofa with orange cushions.

13. Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
2.5 star property
Arnold
9.4 out of 10, Exceptional, (1,008 reviews)
This quiet hotel in Arnold features an outdoor pool and fitness center, with free breakfast and parking. The helpful staff receives high praise from guests, and you'll find BounceU and Arnold Historical Society nearby, with convenient access to St. Louis.
The price is $90
$104 total
includes taxes & fees
Nov 8 - Nov 9
Pear Tree Inn St. Louis Arnold
An outdoor patio with a fire pit, seating, and a building in the background.

14. Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
Richmond Heights
9.4 out of 10, Exceptional, (911 reviews)
Modern accommodations near Forest Park with The Bistro serving meals daily. Just 7 minutes from Brentwood Station, this hotel offers free WiFi, parking, and a welcoming garden area. Guests consistently praise the spotless rooms and attentive staff.
The price is $118
$144 total
includes taxes & fees
Nov 8 - Nov 9
Courtyard by Marriott St. Louis Brentwood
A modern interior with hanging pendant lights, large windows, and a view of the outside.

15. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
7.8 out of 10, Good, (1,626 reviews)
Find unexpected tranquility at this Fenton hotel with dual pools. The quiet atmosphere, convenient location, and free breakfast earn top marks, while nearby Museum of Transportation offers unique exploration. Friendly staff and free parking add value.
The price is $89
$103 total
includes taxes & fees
Nov 3 - Nov 4
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

16. The West End

The West End
2.0 star property
Central West End
8.6 out of 10, Excellent, (707 reviews)
Escape to the vibrant heart of St. Louis at this contemporary hotel near Grand Station. The 24-hour fitness center keeps your workout routine intact while exploring nearby Gateway Arch and Forest Park attractions.
The price is $70
$102 total
includes taxes & fees
Nov 3 - Nov 4
The West End
A hotel lobby with a staircase, dining area, and reception desk.

17. Holiday Inn Express & Suites St. Louis West - Fenton by IHG

Holiday Inn Express & Suites St. Louis West - Fenton by IHG
3.0 star property
Fenton
8.8 out of 10, Excellent, (1,002 reviews)
The price is $93
$107 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Express & Suites St. Louis West - Fenton by IHG
The Clayton Plaza Hotel sign with a stone wall and plants in front.

18. Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Clayton
8.8 out of 10, Excellent, (3,519 reviews)
Steps from Clayton Station, this relaxing hotel offers freshly prepared complimentary breakfast and comfortable rooms. Explore nearby St. Louis Zoo and Washington University, then unwind in the indoor pool after a day of sightseeing.
The price is $105
$123 total
includes taxes & fees
Nov 8 - Nov 9
Clayton Plaza Hotel & Extended Stay
A neatly made bed with white linens and a dark headboard, flanked by two bedside tables with lamps.

19. The Principal Hotel

The Principal Hotel
3.5 star property
Columbia
9.6 out of 10, Exceptional, (457 reviews)
This modern hotel offers free parking and WiFi, perfect for exploring nearby attractions. Work out at the fitness center or enjoy breakfast and dinner at Graphite Restaurant. Triple Lakes Golf Course and Eckert's Millstadt Farm are just a short drive away.
The price is $98
$109 total
includes taxes & fees
Nov 3 - Nov 4
The Principal Hotel
The exterior of the Charles F. Knight Center with a stone facade, large arched entrance, and a sign above the doors.

20. The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
St. Louis
9.4 out of 10, Exceptional, (717 reviews)
Experience easy access to St. Louis attractions from this hotel near Washington University. Relax at the bar or grab a bite at the café after exploring Forest Park. U City Big Bend Station is just 6 minutes away on foot for seamless city adventures.
The price is $122
$140 total
includes taxes & fees
Nov 28 - Nov 29
The Knight Center at Washington University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Go beyond your typical stay in Affton

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Learn more about Affton

Around Affton are top attractions including St. Louis Zoo and St. Louis Union Station.

See all hotels in Affton
A city skyline with a prominent arch bridge over a river, featuring several high-rise buildings and boats on the water.

Check out reviews of Affton hotels guests love

A hotel room with a minibar, a shoe rack, a coat rack, and a TV.
Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG
St. Louis

10/10 Exceptional

Room was beautiful! Taylor at front desk was a gem! Friendly. Great breakfast. Will definitely make this one a regular stop when heading South from Minnesota ❤️
United States
Craig
Reviewed January 30, 2025
Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Frequently Asked Questions

What hotels do travelers like in Affton?

Guests like Clayton Plaza Hotel & Extended Stay, Hyatt Regency St. Louis at The Arch and Angad Arts Hotel St. Louis, Tapestry Collection by Hilton.

Can I book a refundable hotel in Affton?

If you want the flexibility to change your travel plans to Affton, most hotels provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Affton be like during my trip?

The warmest months in Affton are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 38°F. The rainiest months are May and April.

Why should I book my Affton hotel with Hotels.com?

There are lots of reasons to book your Affton trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.