Hotels in Santa Cruz

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Check prices for these dates

Tonight

Sep 13 - Sep 14

Tomorrow

Sep 14 - Sep 15

Next weekend

Sep 18 - Sep 20

In two weeks

Sep 25 - Sep 27

Where to stay in Santa Cruz?

A modern lobby with seating areas, a coffee table, and a large potted plant.

A dessert on a plate with chocolate sauce and nuts, a guitar in the background.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

1. Ibis Santa Cruz DE LA Sierra

Equipetrol

$45

$45 total

Oct 2 - Oct 3

A poolside area with lounge chairs and a palm tree.

A banquet hall with long tables, chandeliers, and draped curtains.

A modern hotel entrance with a curved canopy, large columns, and a well-lit facade.

A pathway through a lush garden with various trees and shrubs.

2. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Equipetrol

$144

$144 total

Oct 1 - Oct 2

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A spacious lobby with high ceilings, large windows, and a modern chandelier.

A large, illuminated swimming pool surrounded by palm trees and pathways.

A restaurant with a long counter, dark chairs, and hanging lights.

3. Camino Real Hotel

Santa Cruz

$149

$149 total

Sep 14 - Sep 15

A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

A restaurant with a high ceiling, large windows, and a view of the cityscape. Tables are set with plates, glasses, and cutlery.

A modern lobby with a dining area, sofas, and a decorative wall.

A modern lobby with a curved staircase, seating area, and a large wooden bookshelf.

4. Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

$106

$106 total

Oct 2 - Oct 3

A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.

A hotel room with a large bed, a TV mounted on the wall, a dining area with chairs, and a sofa.

A modern staircase with glass railings, leading to a landing with a small garden area.

A buffet setup with various food items, including pastries, a cake, and beverages.

5. Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

$46

$46 total

Sep 14 - Sep 15

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.

A buffet with various fruits and snacks.

A spacious lobby with high ceilings, wooden beams, and a large seating area with wicker chairs.

6. Hotel Cortez

Equipetrol

$130

$130 total

Oct 4 - Oct 5

A modern restaurant with a city view, featuring glass tables, white chairs, and a large window with curtains.

A small, enclosed garden area with various potted plants and a gravel path.

A hotel room with a large bed, a desk, a chair, a telephone, and a view of the city through large windows.

A modern hotel lobby with a bar area, seating arrangements, and a television.

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Santa Cruz

$74

$74 total

Oct 2 - Oct 3

A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

A modern hotel room with a cityscape view at sunset, a tufted headboard, and a neatly made bed with white linens and dark accents.

A rooftop pool area with a view of the city skyline at dusk.

A modern lounge area with leather sofas, a coffee table, and a view of a green wall with plants.

8. TRYP by Wyndham Santa Cruz

Equipetrol

$87

$87 total

Sep 14 - Sep 15

A modern hotel room with a large bed, bedside tables, a desk with a chair, a small fridge, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

9. HOTEL OSHO

Santa Cruz

$44

$44 total

Sep 14 - Sep 15

A rooftop pool with a glass barrier reflecting the sunset and city skyline.

A hotel room with two beds, a desk, and a view of the city.

A modern building with a stone facade and large windows. The name 'DEFINES COLLECTION' is prominently displayed on the building.

An outdoor dining area with tables and chairs, a wooden pergola with hanging lights, and a city view.

10. Delfines Collection Hotel By Mercure

Equipetrol

$55

$55 total

Oct 1 - Oct 2

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

A modern outdoor pool area with a red brick wall, a large mural, and outdoor furniture.

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

11. Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$108

$108 total

Sep 24 - Sep 25

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A window seat with a view of a cityscape at dusk.

12. Novotel Santa Cruz De La Sierra

Santa Cruz

$115

$115 total

Oct 12 - Oct 13

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A buffet setup with various food items and a serving area.

A hotel room with two beds, a desk, a television, and a small kitchenette.

A man in a suit entering an elevator.

13. Hotel Las Américas

Centro Histórico

$26

$26 total

Sep 14 - Sep 15

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

Wicker furniture with cushions, potted plants, and a ceiling with lights.

A spacious restaurant with wooden flooring, tables with red and white tablecloths, and wicker chairs.

A traditional-style room with a sofa set, a table, and two chairs.

14. Lido Hotel

Centro Histórico

$25

$25 total

Sep 14 - Sep 15

A buffet setup with various food items and beverages.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A corridor with wooden doors, orange walls, and a carpeted floor.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

15. Hotel LP Equipetrol

Equipetrol

$44

$49 total

Sep 30 - Oct 1

A spacious room with a wooden floor and large windows offering a city view.

A modern lobby with a marble floor, a chandelier, and potted plants.

A buffet table with various food items and a wine bottle.

A modern gym with a treadmill, a glass table with fitness items, and a city view through large windows.

16. Swissôtel Santa Cruz De La Sierra

Santa Cruz

$131

$131 total

Oct 2 - Oct 3

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A multi-level atrium with a central planter containing various plants, surrounded by glass railings and a brick wall.

A room with a large window, a brick wall, and a hanging plant.

A spacious lobby with a brick accent wall, a seating area with a coffee table, and a view of the kitchen in the background.

17. Chairú Eco Hotel

Santa Cruz

$49

$49 total

Oct 4 - Oct 5

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A table set for a meal with a view of a body of water and decorative lighting.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

18. Sun Hotel

Santa Cruz

$108

$108 total

Sep 18 - Sep 19

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

19. Cosmopolitano Hotel Boutique

Centro Histórico

$58

$58 total

Sep 28 - Sep 29

An outdoor dining area with tables and chairs, surrounded by plants and palm trees.

A kitchen with granite countertops, wooden chairs, a microwave, and a window.

A residential street with modern buildings, parked cars, and palm trees.

A modern hotel with a swimming pool, lounge chairs, and a clear sky.

20. Terranova Suites

Santa Cruz

$52

$52 total

Sep 14 - Sep 15

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A modern lobby with seating areas, a coffee table, and a large potted plant.

A dessert on a plate with chocolate sauce and nuts, a guitar in the background.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$62

per night

$125 total

A modern hotel room with a large bed, bedside tables, a desk with a chair, a small fridge, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

HOTEL OSHO

Santa Cruz

$62 off

$48

per night

$95 total

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

Wicker furniture with cushions, potted plants, and a ceiling with lights.

A spacious restaurant with wooden flooring, tables with red and white tablecloths, and wicker chairs.

A traditional-style room with a sofa set, a table, and two chairs.

Lido Hotel

Centro Histórico

$6 off

$27

per night

$53 total

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A spacious lobby with high ceilings, large windows, and a modern chandelier.

A large, illuminated swimming pool surrounded by palm trees and pathways.

A restaurant with a long counter, dark chairs, and hanging lights.

Camino Real Hotel

Santa Cruz

$243 off

$207

per night

$414 total

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A multi-level atrium with a central planter containing various plants, surrounded by glass railings and a brick wall.

A room with a large window, a brick wall, and a hanging plant.

A spacious lobby with a brick accent wall, a seating area with a coffee table, and a view of the kitchen in the background.

Chairú Eco Hotel

Santa Cruz

$43 off

$64

per night

$128 total

A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.

A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.

A hotel entrance with glass doors, a sign reading "LP HOTELES", and a green wall.

A modern restaurant interior with high tables and chairs, a large window with a view of the city, and a mural of a pink cherry blossom tree.

Hotel LP Santa Cruz Centro

Santa Cruz

$51 off

$54

per night

$114 total

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A window seat with a view of a cityscape at dusk.

Novotel Santa Cruz De La Sierra

Santa Cruz

$180

per night

$360 total

A buffet setup with various food items and beverages.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A corridor with wooden doors, orange walls, and a carpeted floor.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

Hotel LP Equipetrol

Equipetrol

$70 off

$56

per night

$117 total

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A table set for a meal with a view of a body of water and decorative lighting.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

Sun Hotel

Santa Cruz

$66 off

$97

per night

$194 total

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A buffet setup with various food items and a serving area.

A hotel room with two beds, a desk, a television, and a small kitchenette.

A man in a suit entering an elevator.

Hotel Las Américas

Centro Histórico

$7 off

$32

per night

$65 total

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

A modern bathroom with a glass shower, a potted plant, and a towel rack.

Hotel G

Santa Cruz

$13 off

$36

per night

$72 total

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

A modern outdoor pool area with a red brick wall, a large mural, and outdoor furniture.

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$30 off

$134

per night

$268 total

A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

A group of women standing in a modern interior with wooden paneling and a reception desk.

A balcony with two wooden chairs and a table, overlooking a cityscape with various buildings.

A dining area with a glass table, metal chairs, and a buffet setup. There is a red sofa in the living area and a kitchen in the background.

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

$6 off

$27

per night

$54 total

A spacious lobby with a high ceiling, modern furniture, and a large chandelier.

A rooftop bar with a pool, lounge chairs, and a city view.

A modern interior with a white sofa, a dining area, and a staircase.

A breakfast table with plates of food, glasses of juice, and a cup of coffee.

Hotel Arenal

Centro Histórico

$21 off

$59

per night

$119 total

A modern rooftop pool with a city view, wooden flooring, and a seating area.

A modern living room with a sofa and a kitchen area featuring a microwave, kettle, and a coffee machine.

A modern office space with a dark wood desk, a black office chair, a flat-screen TV mounted on the wall, and an air conditioning unit.

A modern hotel room with a bed, bedside table, and a desk with a chair.

AMERICA APARTMENTS

Santa Cruz

$10 off

$45

per night

$89 total

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

Cosmopolitano Hotel Boutique

Centro Histórico

$19 off

$58

per night

$58 total

A modern lobby with seating areas, a coffee table, and a large potted plant.

A dessert on a plate with chocolate sauce and nuts, a guitar in the background.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$50

per night

$50 total

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A table set for a meal with a view of a body of water and decorative lighting.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

Sun Hotel

Santa Cruz

$13 off

$117

per night

$117 total

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A spacious lobby with high ceilings, large windows, and a modern chandelier.

A large, illuminated swimming pool surrounded by palm trees and pathways.

A restaurant with a long counter, dark chairs, and hanging lights.

Camino Real Hotel

Santa Cruz

$195

per night

$195 total

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A window seat with a view of a cityscape at dusk.

Novotel Santa Cruz De La Sierra

Santa Cruz

$115

per night

$115 total

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

Wicker furniture with cushions, potted plants, and a ceiling with lights.

A spacious restaurant with wooden flooring, tables with red and white tablecloths, and wicker chairs.

A traditional-style room with a sofa set, a table, and two chairs.

Lido Hotel

Centro Histórico

$3 off

$25

per night

$25 total

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

A modern outdoor pool area with a red brick wall, a large mural, and outdoor furniture.

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$67 off

$108

per night

$108 total

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.

A buffet with various fruits and snacks.

A spacious lobby with high ceilings, wooden beams, and a large seating area with wicker chairs.

Hotel Cortez

Equipetrol

$134

per night

$134 total

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A multi-level atrium with a central planter containing various plants, surrounded by glass railings and a brick wall.

A room with a large window, a brick wall, and a hanging plant.

A spacious lobby with a brick accent wall, a seating area with a coffee table, and a view of the kitchen in the background.

Chairú Eco Hotel

Santa Cruz

$19 off

$56

per night

$56 total

A spacious room with a wooden floor and large windows offering a city view.

A modern lobby with a marble floor, a chandelier, and potted plants.

A buffet table with various food items and a wine bottle.

A modern gym with a treadmill, a glass table with fitness items, and a city view through large windows.

Swissôtel Santa Cruz De La Sierra

Santa Cruz

$131

per night

$131 total

A modern hotel room with a large bed, bedside tables, a desk with a chair, a small fridge, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

HOTEL OSHO

Santa Cruz

$7 off

$65

per night

$65 total

A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.

A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.

A hotel entrance with glass doors, a sign reading "LP HOTELES", and a green wall.

A modern restaurant interior with high tables and chairs, a large window with a view of the city, and a mural of a pink cherry blossom tree.

Hotel LP Santa Cruz Centro

Santa Cruz

$24 off

$52

per night

$57 total

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

A modern bathroom with a glass shower, a potted plant, and a towel rack.

Hotel G

Santa Cruz

$11 off

$25

per night

$25 total

A buffet setup with various food items and beverages.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A corridor with wooden doors, orange walls, and a carpeted floor.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

Hotel LP Equipetrol

Equipetrol

$22 off

$52

per night

$57 total

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A buffet setup with various food items and a serving area.

A hotel room with two beds, a desk, a television, and a small kitchenette.

A man in a suit entering an elevator.

Hotel Las Américas

Centro Histórico

$3 off

$26

per night

$26 total

Check out pet-friendly hotels in Santa Cruz

A modern lobby with seating areas, a coffee table, and a large potted plant.

A dessert on a plate with chocolate sauce and nuts, a guitar in the background.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$45

$45 total

Oct 2 - Oct 3

A modern rooftop pool with a city view, wooden flooring, and a seating area.

A modern living room with a sofa and a kitchen area featuring a microwave, kettle, and a coffee machine.

A modern office space with a dark wood desk, a black office chair, a flat-screen TV mounted on the wall, and an air conditioning unit.

A modern hotel room with a bed, bedside table, and a desk with a chair.

AMERICA APARTMENTS

Santa Cruz

$34

$34 total

Oct 3 - Oct 4

A buffet setup with various food items and beverages.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A corridor with wooden doors, orange walls, and a carpeted floor.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

Hotel LP Equipetrol

Equipetrol

$44

$49 total

Sep 30 - Oct 1

A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.

A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.

A hotel entrance with glass doors, a sign reading "LP HOTELES", and a green wall.

A modern restaurant interior with high tables and chairs, a large window with a view of the city, and a mural of a pink cherry blossom tree.

Hotel LP Santa Cruz Centro

Santa Cruz

$49

$54 total

Sep 30 - Oct 1

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

A modern bathroom with a glass shower, a potted plant, and a towel rack.

Hotel G

Santa Cruz

$25

$25 total

Oct 12 - Oct 13

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

Cosmopolitano Hotel Boutique

Centro Histórico

$58

$58 total

Sep 28 - Sep 29

A modern hotel room with a large bed, bedside tables, a desk with a chair, a small fridge, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

HOTEL OSHO

Santa Cruz

$44

$44 total

Sep 14 - Sep 15

A room with a red sofa, a small black table, and a wooden door.

A hotel room with two beds, a desk with a lamp, a chair, and a large window with curtains.

A grand staircase with ornate railings, marble flooring, and a seating area with purple armchairs.

A hotel room with a bed, a desk, a chair, a table, a TV, and a mirror.

Gran Hotel Santa Cruz

Centro Histórico

$58

$58 total

Sep 14 - Sep 15

A hotel room with two beds, a desk, a chair, a lamp, and a sliding glass door leading to an outdoor area.

A multi-story hotel with a prominent sign for the Gran Hotel Mediterano.

A hotel room with a bed, a table with a green tablecloth, a potted plant, and a view of the outside.

A buffet table with various food items and condiments, including a coffee station, a juice dispenser, and a sign labeled 'Windsor'.

Gran Hotel Mediterráneo

Centro Histórico

$37

$37 total

Sep 14 - Sep 15

Prince Hotel

Santa Cruz

$49

$51 total

Sep 14 - Sep 15

View all properties

You may also like hotels with pools in Santa Cruz

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

Cosmopolitano Hotel Boutique

Centro Histórico

$58

$58 total

Sep 28 - Sep 29

A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

A restaurant with a high ceiling, large windows, and a view of the cityscape. Tables are set with plates, glasses, and cutlery.

A modern lobby with a dining area, sofas, and a decorative wall.

A modern lobby with a curved staircase, seating area, and a large wooden bookshelf.

Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

$106

$106 total

Oct 2 - Oct 3

A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

A modern hotel room with a cityscape view at sunset, a tufted headboard, and a neatly made bed with white linens and dark accents.

A rooftop pool area with a view of the city skyline at dusk.

A modern lounge area with leather sofas, a coffee table, and a view of a green wall with plants.

TRYP by Wyndham Santa Cruz

Equipetrol

$87

$87 total

Sep 14 - Sep 15

A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.

A hotel room with a large bed, a TV mounted on the wall, a dining area with chairs, and a sofa.

A modern staircase with glass railings, leading to a landing with a small garden area.

A buffet setup with various food items, including pastries, a cake, and beverages.

Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

$46

$46 total

Sep 14 - Sep 15

A poolside area with lounge chairs and a palm tree.

A banquet hall with long tables, chandeliers, and draped curtains.

A modern hotel entrance with a curved canopy, large columns, and a well-lit facade.

A pathway through a lush garden with various trees and shrubs.

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Equipetrol

$144

$144 total

Oct 1 - Oct 2

A modern hotel room with a large bed, bedside tables, a desk with a chair, a small fridge, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

HOTEL OSHO

Santa Cruz

$44

$44 total

Sep 14 - Sep 15

A room with a red sofa, a small black table, and a wooden door.

A hotel room with two beds, a desk with a lamp, a chair, and a large window with curtains.

A grand staircase with ornate railings, marble flooring, and a seating area with purple armchairs.

A hotel room with a bed, a desk, a chair, a table, a TV, and a mirror.

Gran Hotel Santa Cruz

Centro Histórico

$58

$58 total

Sep 14 - Sep 15

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A window seat with a view of a cityscape at dusk.

Novotel Santa Cruz De La Sierra

Santa Cruz

$115

$115 total

Oct 12 - Oct 13

A modern rooftop pool with a city view, wooden flooring, and a seating area.

A modern living room with a sofa and a kitchen area featuring a microwave, kettle, and a coffee machine.

A modern office space with a dark wood desk, a black office chair, a flat-screen TV mounted on the wall, and an air conditioning unit.

A modern hotel room with a bed, bedside table, and a desk with a chair.

AMERICA APARTMENTS

Santa Cruz

$34

$34 total

Oct 3 - Oct 4

A room with a central decorative object emitting steam, surrounded by dark tiled walls and a tiled floor.

A swimming pool with a thatched-roof structure and palm trees in the background.

A room with wooden paneling, a brick wall, and a bench area.

A hotel entrance with a stone wall and a sign that reads 'MORAGRANDE Hotel y Centro de Convenciones.'

Mora Grande

Santa Cruz

$63

$63 total

Sep 15 - Sep 16

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Go beyond your typical stay in Santa Cruz

Pet friendly

Pool

Spa

Hot tub

Family friendly

Our prices for hotels in Santa Cruz are cheapest in February

Top neighborhoods in Santa Cruz

Hamacas

Centro Histórico

Santa Cruz's Centro Histórico neighborhood is home to attractions such as Plaza 24 de Septiembre and La Recova Artisan Walk.

Urubó

Zona Sur (South Zone)

Equipetrol

Santa Cruz's Equipetrol neighborhood offers attractions including Santa Cruz Zoo.

Top landmarks in Santa Cruz

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)

If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre— just one of the monuments in central Santa Cruz.

An interior of a church with high arched ceilings, wooden pews, and a central altar.

San Lorenzo Cathedral

9.0/10 (84 reviews)

Centro Histórico is home to San Lorenzo Cathedral, so why not stop by during your stay in Santa Cruz.

Ventura Mall

9.0/10 (183 reviews)

If you like shopping, take time out to go to Ventura Mall when in Santa Cruz.

Guembe Biocenter

8.8/10 (60 reviews)

Ready for an education in local botany? Guembe Biocenter should make your list of places to visit, located 1.2 mi (2 km) from central Colinas del Urubo. Want to stretch your legs some more? Head to Arenal Park, located nearby.

Santa Cruz Zoo

8.4/10 (53 reviews)

It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a trip to Santa Cruz Zoo, located 1.7 mi (2.8 km) from central Santa Cruz. If you have fun at Santa Cruz Zoo, you'll love Guembe Biocenter and Artecampo, both located nearby.

Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)

You can catch an event at Ramon Tahuichi Aguilera Stadium, located 0.8 mi (1.3 km) from central Santa Cruz.

Blacutt Square

8.2/10 (19 reviews)

You might want to get your camera out and head to Blacutt Square— just one of the landmarks located 0.7 mi (1.1 km) from central Santa Cruz.

Cine Center

8.0/10 (53 reviews)

Cine Center is 1 mi (1.6 km) from central Santa Cruz, why not stop by during your stay. If you enjoy the show and want to see another, Casa Municipal de Cultura Raúl Otero Reiche isn't far.

Learn more about Santa Cruz

Santa Cruz is applauded for its cultural attractions such as Ethno-folkloric Museum and Cine Center.

See all hotels in Santa Cruz

A colonial-style building with a bell tower, palm trees, and a paved walkway.

Check out reviews of Santa Cruz hotels guests love

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

10/10 Excellent

"Very nice place to stay and enjoy the climate in Santa Cruz. Many amenities and friendly staff."

Hotel Cortez

Hotel Cortez

10/10 Excellent

"Awesome Hotel"

Sun Hotel

Sun Hotel

10/10 Excellent

"Very nice place to stay. Close to the airport with shuttle to the hotel."

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

10/10 Excellent

"We had a great stay here. The rooms were clean and comfortable. Will return!"

Camino Real Hotel

Camino Real Hotel

10/10 Excellent

"The food is excellent quality and delicious! Friendly staff"

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

10/10 Excellent

"The room was very clean and the breakfast was fantastic. Overall it was a great experience."

Hotel Las Américas

Hotel Las Américas

10/10 Excellent

"DELICIOSO EL DESAYUNO"

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

10/10 Excellent

"All around good price and location"

HOTEL OSHO

HOTEL OSHO

10/10 Excellent

"Good"

Frequently asked questions

What hotels do travelers recommend in Santa Cruz?

Guests like Ibis Santa Cruz DE LA Sierra, Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Marriott Santa Cruz de la Sierra Hotel.

Where can I find free parking at my hotel in Santa Cruz?

These hotels offer the perk of free parking: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Swissôtel Santa Cruz De La Sierra and Hotel LP Equipetrol. There are 8 options you may want to check out on our site.

Can I book refundable hotels in Santa Cruz?

If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where should I consider staying in Santa Cruz if I'm looking for a reasonably priced accommodation?

An inexpensive option worth considering is Hotel LP Equipetrol. You can browse all 7 choices on our site.

Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?

If you want to find a good alternative to a hotel, browse our selection of 24 vacation homes. In addition, you can choose from 199 apartments.

What will the weather in Santa Cruz be like during my trip?

Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.

Why should I book my Santa Cruz accommodation with Hotels.com?

There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.