Hotels in Santa Cruz

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Check prices for these dates

Tonight

Oct 25 - Oct 26

Tomorrow

Oct 26 - Oct 27

Next weekend

In two weeks

Where to stay in Santa Cruz?

A hotel entrance with a modern design, glass doors, and a sign reading 'ibis HOTEL'.

A modern lounge area with sofas, tables, and potted plants.

A hotel room with a large bed, a desk, a chair, a window with curtains, and artwork on the wall.

A modern lobby with seating areas, a coffee table, and a large potted plant.

1. Ibis Santa Cruz DE LA Sierra

Equipetrol

$42

$42 total

Oct 30 - Oct 31

A poolside area with lounge chairs and a palm tree.

A modern hotel entrance with a curved canopy, large columns, and a well-lit facade.

A pathway through a lush garden with various trees and shrubs.

A dining table with breakfast items and a pool view.

2. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Equipetrol

$135

$135 total

Nov 15 - Nov 16

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

An aerial view of a resort with a large swimming pool, multiple lounge areas, and surrounding greenery.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

A restaurant with a long counter, dark chairs, and hanging lights.

3. Camino Real Hotel

Santa Cruz

$164

$164 total

Nov 1 - Nov 2

A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

A luxurious banquet hall with ornate chandeliers, floral arrangements, and elegant table settings.

A modern lobby with a curved staircase, seating area, and a large wooden bookshelf.

A restaurant with a high ceiling, large windows, and a view of the cityscape. Tables are set with plates, glasses, and cutlery.

4. Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

$123

$123 total

Nov 1 - Nov 2

A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.

A modern lobby with wooden paneling, two grey sofas, and pendant lighting.

A modern staircase with glass railings, leading to a landing with a small garden area.

A buffet setup with various food items, including pastries, a cake, and beverages.

5. Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

$46

$46 total

Oct 26 - Oct 27

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.

A buffet with various fruits and snacks.

A spacious lobby with high ceilings, wooden beams, and a large seating area with wicker chairs.

6. Hotel Cortez

Equipetrol

$130

$130 total

Oct 31 - Nov 1

A modern hotel lobby with a bar area, seating arrangements, and a television.

A modern restaurant with a city view, featuring glass tables, white chairs, and a large window with curtains.

A small, enclosed garden area with various potted plants and a gravel path.

A hotel room with a large bed, a desk, a chair, a telephone, and a view of the city through large windows.

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Santa Cruz

$74

$74 total

Oct 30 - Oct 31

A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

A rooftop pool area with a view of the city skyline at dusk.

A reception area with a marble counter, a large chandelier, and a digital display.

A modern hotel room with a cityscape view at sunset, a tufted headboard, and a neatly made bed with white linens and dark accents.

8. TRYP by Wyndham Santa Cruz

Equipetrol

$109

$109 total

Nov 1 - Nov 2

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

9. HOTEL OSHO

Santa Cruz

$51

$51 total

Oct 29 - Oct 30

A hotel room with two beds, a desk, and a view of the city.

A modern building with a stone facade and large windows. The name 'DEFINES COLLECTION' is prominently displayed on the building.

A buffet with various food items and a pitcher of orange juice.

An outdoor dining area with tables and chairs, a wooden pergola with hanging lights, and a city view.

10. Delfines Collection Hotel By Mercure

Equipetrol

$48

$48 total

Nov 9 - Nov 10

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A modern outdoor pool area with a red brick wall, a large mural, and outdoor furniture.

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

11. Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$108

$108 total

Nov 23 - Nov 24

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

12. Novotel Santa Cruz De La Sierra

Santa Cruz

$119

$119 total

Nov 23 - Nov 24

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A man in a suit entering an elevator.

A hotel room with two beds, a desk, a television, and a small kitchenette.

A buffet setup with various food items and a serving area.

13. Hotel Las Américas

Centro Histórico

$26

$26 total

Oct 26 - Oct 27

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

Wicker furniture with cushions, potted plants, and a ceiling with lights.

A staircase with ornate lion statues at the base, a chandelier, and a framed artwork on the wall.

A traditional-style room with a sofa set, a table, and two chairs.

14. Lido Hotel

Centro Histórico

$25

$25 total

Oct 27 - Oct 28

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

A corridor with wooden doors, orange walls, and a carpeted floor.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

15. Hotel LP Equipetrol

Equipetrol

$45

$50 total

Nov 13 - Nov 14

A hotel room with a large window, a bed, a desk with a telephone, and a television.

A modern restaurant with large windows, a central dining area with tables and chairs, and a view of the outdoors.

A hotel room with two beds, a nightstand, and a wall-mounted lamp.

A spacious room with a wooden floor and large windows offering a city view.

16. Swissôtel Santa Cruz De La Sierra

Santa Cruz

$131

$131 total

Nov 14 - Nov 15

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A multi-level atrium with a central planter containing various plants, surrounded by glass railings and a brick wall.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A room with a large window, a brick wall, and a hanging plant.

17. Chairú Eco Hotel

Santa Cruz

$47

$47 total

Nov 1 - Nov 2

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

A table set for a meal with a view of a body of water and decorative lighting.

18. Sun Hotel

Santa Cruz

$97

$97 total

Nov 7 - Nov 8

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A building with a sign that reads "COSMOPOLITANO."

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

19. Cosmopolitano Hotel Boutique

Centro Histórico

$53

$53 total

Nov 2 - Nov 3

A modern hotel with a swimming pool, lounge chairs, and a clear sky.

A kitchen with granite countertops, wooden chairs, a microwave, and a window.

A residential street with modern buildings, parked cars, and palm trees.

An outdoor dining area with tables and chairs, surrounded by plants and palm trees.

20. Terranova Suites

Santa Cruz

$52

$52 total

Oct 26 - Oct 27

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Room

Reception

Rooftop terrace

Room

Hotel Maywa

Santa Cruz

$10 off

$44

per night

$88 total

A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

A luxurious banquet hall with ornate chandeliers, floral arrangements, and elegant table settings.

A modern lobby with a curved staircase, seating area, and a large wooden bookshelf.

A restaurant with a high ceiling, large windows, and a view of the cityscape. Tables are set with plates, glasses, and cutlery.

Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

$54 off

$152

per night

$304 total

A hotel entrance with a modern design, glass doors, and a sign reading 'ibis HOTEL'.

A modern lounge area with sofas, tables, and potted plants.

A hotel room with a large bed, a desk, a chair, a window with curtains, and artwork on the wall.

A modern lobby with seating areas, a coffee table, and a large potted plant.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$44 off

$64

per night

$127 total

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A multi-level atrium with a central planter containing various plants, surrounded by glass railings and a brick wall.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A room with a large window, a brick wall, and a hanging plant.

Chairú Eco Hotel

Santa Cruz

$51 off

$49

per night

$99 total

A swimming pool with a fountain, surrounded by a deck and a building with a dome and bell tower.

A spacious living area with a black sofa, a glass coffee table, and a plant.

A room with a glass table and chair, a lamp, and a view of a brick building through large windows.

A hotel room with two beds, a red sofa, a desk, a television, and a city view through the window.

Hotel Pascana centro

Centro Histórico

$17 off

$77

per night

$155 total

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A modern outdoor pool area with a red brick wall, a large mural, and outdoor furniture.

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$101 off

$125

per night

$249 total

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$29 off

$44

per night

$88 total

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

An aerial view of a resort with a large swimming pool, multiple lounge areas, and surrounding greenery.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

A restaurant with a long counter, dark chairs, and hanging lights.

Camino Real Hotel

Santa Cruz

$185

per night

$369 total

A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

A dining area with a glass table, metal chairs, and a buffet setup. There is a red sofa in the living area and a kitchen in the background.

A group of women standing in a modern interior with wooden paneling and a reception desk.

A reception desk with a wooden panel wall behind it, displaying the text "Premium Suites".

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

$6 off

$27

per night

$54 total

A spacious lobby with a high ceiling, modern furniture, and a large chandelier.

A modern interior with a white sofa, a dining area, and a staircase.

A spacious, well-lit interior with a modern white sofa set, a glass coffee table, and a dining area with red tablecloths.

A breakfast table with plates of food, glasses of juice, and a cup of coffee.

Hotel Arenal

Centro Histórico

$13 off

$57

per night

$113 total

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

A corridor with wooden doors, orange walls, and a carpeted floor.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

Hotel LP Equipetrol

Equipetrol

$21 off

$60

per night

$125 total

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

A modern bathroom with a glass shower, a potted plant, and a towel rack.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

Hotel G

Santa Cruz

$11 off

$30

per night

$60 total

A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.

A modern restaurant interior with high tables and chairs, a large window with a view of the city, and a mural of a pink cherry blossom tree.

A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.

A modern reception area with a grey reception desk labeled "hola. bienvenido".

Hotel LP Santa Cruz Centro

Santa Cruz

$69 off

$54

per night

$113 total

A hotel room with a bed, a table with flowers, a view of the outside, and a wardrobe.

Breakfast buffet

A compact room with a small table, a refrigerator, and a trash bin.

A multi-story hotel with a prominent sign for the Gran Hotel Mediterraneo.

Gran Hotel Mediterráneo

Centro Histórico

$12 off

$55

per night

$109 total

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

A table set for a meal with a view of a body of water and decorative lighting.

Sun Hotel

Santa Cruz

$105

per night

$211 total

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A building with a sign that reads "COSMOPOLITANO."

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

Cosmopolitano Hotel Boutique

Centro Histórico

$57

per night

$57 total

A hotel entrance with a modern design, glass doors, and a sign reading 'ibis HOTEL'.

A modern lounge area with sofas, tables, and potted plants.

A hotel room with a large bed, a desk, a chair, a window with curtains, and artwork on the wall.

A modern lobby with seating areas, a coffee table, and a large potted plant.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$50

per night

$50 total

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A modern outdoor pool area with a red brick wall, a large mural, and outdoor furniture.

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$67 off

$108

per night

$108 total

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

A table set for a meal with a view of a body of water and decorative lighting.

Sun Hotel

Santa Cruz

$22 off

$108

per night

$108 total

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A multi-level atrium with a central planter containing various plants, surrounded by glass railings and a brick wall.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A room with a large window, a brick wall, and a hanging plant.

Chairú Eco Hotel

Santa Cruz

$28 off

$47

per night

$47 total

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

Wicker furniture with cushions, potted plants, and a ceiling with lights.

A staircase with ornate lion statues at the base, a chandelier, and a framed artwork on the wall.

A traditional-style room with a sofa set, a table, and two chairs.

Lido Hotel

Centro Histórico

$3 off

$25

per night

$25 total

A swimming pool with a fountain, surrounded by a deck and a building with a dome and bell tower.

A spacious living area with a black sofa, a glass coffee table, and a plant.

A room with a glass table and chair, a lamp, and a view of a brick building through large windows.

A hotel room with two beds, a red sofa, a desk, a television, and a city view through the window.

Hotel Pascana centro

Centro Histórico

$19 off

$77

per night

$77 total

Room

Reception

Rooftop terrace

Room

Hotel Maywa

Santa Cruz

$5 off

$44

per night

$44 total

A spacious lobby with a high ceiling, modern furniture, and a large chandelier.

A modern interior with a white sofa, a dining area, and a staircase.

A spacious, well-lit interior with a modern white sofa set, a glass coffee table, and a dining area with red tablecloths.

A breakfast table with plates of food, glasses of juice, and a cup of coffee.

Hotel Arenal

Centro Histórico

$6 off

$57

per night

$57 total

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

An aerial view of a resort with a large swimming pool, multiple lounge areas, and surrounding greenery.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

A restaurant with a long counter, dark chairs, and hanging lights.

Camino Real Hotel

Santa Cruz

$164

per night

$164 total

A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

A dining area with a glass table, metal chairs, and a buffet setup. There is a red sofa in the living area and a kitchen in the background.

A group of women standing in a modern interior with wooden paneling and a reception desk.

A reception desk with a wooden panel wall behind it, displaying the text "Premium Suites".

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

$3 off

$27

per night

$27 total

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$6 off

$56

per night

$56 total

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

A modern bathroom with a glass shower, a potted plant, and a towel rack.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

Hotel G

Santa Cruz

$12 off

$27

per night

$27 total

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

A corridor with wooden doors, orange walls, and a carpeted floor.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

Hotel LP Equipetrol

Equipetrol

$25 off

$49

per night

$54 total

A hotel room with a bed, a table with flowers, a view of the outside, and a wardrobe.

Breakfast buffet

A compact room with a small table, a refrigerator, and a trash bin.

A multi-story hotel with a prominent sign for the Gran Hotel Mediterraneo.

Gran Hotel Mediterráneo

Centro Histórico

$6 off

$55

per night

$55 total

Check out pet-friendly hotels in Santa Cruz

A hotel entrance with a modern design, glass doors, and a sign reading 'ibis HOTEL'.

A modern lounge area with sofas, tables, and potted plants.

A hotel room with a large bed, a desk, a chair, a window with curtains, and artwork on the wall.

A modern lobby with seating areas, a coffee table, and a large potted plant.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$42

$42 total

Oct 30 - Oct 31

A spiral staircase with a view of the sky and a sign reading 'ENTRADA'.

A swimming pool with a children's play area, a building with a mural, and palm trees.

A lobby with a marble floor, an elevator, and a view of the outdoor seating area.

A hotel room with two beds, a desk with a lamp, a chair, and a large window with curtains.

Gran Hotel Santa Cruz

Centro Histórico

$73

$73 total

Oct 26 - Oct 27

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A building with a sign that reads "COSMOPOLITANO."

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

Cosmopolitano Hotel Boutique

Centro Histórico

$53

$53 total

Nov 2 - Nov 3

A swimming pool with a fountain, surrounded by a deck and a building with a dome and bell tower.

A spacious living area with a black sofa, a glass coffee table, and a plant.

A room with a glass table and chair, a lamp, and a view of a brick building through large windows.

A hotel room with two beds, a red sofa, a desk, a television, and a city view through the window.

Hotel Pascana centro

Centro Histórico

$90

$90 total

Oct 26 - Oct 27

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$51

$51 total

Oct 29 - Oct 30

A hotel room with a bed, a table with flowers, a view of the outside, and a wardrobe.

Breakfast buffet

A compact room with a small table, a refrigerator, and a trash bin.

A multi-story hotel with a prominent sign for the Gran Hotel Mediterraneo.

Gran Hotel Mediterráneo

Centro Histórico

$55

$55 total

Oct 26 - Oct 27

Room

Reception

Rooftop terrace

Room

Hotel Maywa

Santa Cruz

$44

$44 total

Oct 26 - Oct 27

A hotel room with a large window, a bed, a desk with a telephone, and a television.

A modern restaurant with large windows, a central dining area with tables and chairs, and a view of the outdoors.

A hotel room with two beds, a nightstand, and a wall-mounted lamp.

A spacious room with a wooden floor and large windows offering a city view.

Swissôtel Santa Cruz De La Sierra

Santa Cruz

$131

$131 total

Nov 14 - Nov 15

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

A modern bathroom with a glass shower, a potted plant, and a towel rack.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

Hotel G

Santa Cruz

$27

$27 total

Nov 24 - Nov 25

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

A corridor with wooden doors, orange walls, and a carpeted floor.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

Hotel LP Equipetrol

Equipetrol

$45

$50 total

Nov 13 - Nov 14

View all properties

You can also stay at hotels with a pool in Santa Cruz

A poolside area with lounge chairs and a palm tree.

A modern hotel entrance with a curved canopy, large columns, and a well-lit facade.

A pathway through a lush garden with various trees and shrubs.

A dining table with breakfast items and a pool view.

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Equipetrol

$135

$135 total

Nov 15 - Nov 16

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.

A buffet with various fruits and snacks.

A spacious lobby with high ceilings, wooden beams, and a large seating area with wicker chairs.

Hotel Cortez

Equipetrol

$130

$130 total

Oct 31 - Nov 1

A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

A luxurious banquet hall with ornate chandeliers, floral arrangements, and elegant table settings.

A modern lobby with a curved staircase, seating area, and a large wooden bookshelf.

A restaurant with a high ceiling, large windows, and a view of the cityscape. Tables are set with plates, glasses, and cutlery.

Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

$123

$123 total

Nov 1 - Nov 2

A spiral staircase with a view of the sky and a sign reading 'ENTRADA'.

A swimming pool with a children's play area, a building with a mural, and palm trees.

A lobby with a marble floor, an elevator, and a view of the outdoor seating area.

A hotel room with two beds, a desk with a lamp, a chair, and a large window with curtains.

Gran Hotel Santa Cruz

Centro Histórico

$73

$73 total

Oct 26 - Oct 27

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

A table set for a meal with a view of a body of water and decorative lighting.

Sun Hotel

Santa Cruz

$97

$97 total

Nov 7 - Nov 8

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A building with a sign that reads "COSMOPOLITANO."

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

Cosmopolitano Hotel Boutique

Centro Histórico

$53

$53 total

Nov 2 - Nov 3

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$51

$51 total

Oct 29 - Oct 30

A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

A rooftop pool area with a view of the city skyline at dusk.

A reception area with a marble counter, a large chandelier, and a digital display.

A modern hotel room with a cityscape view at sunset, a tufted headboard, and a neatly made bed with white linens and dark accents.

TRYP by Wyndham Santa Cruz

Equipetrol

$109

$109 total

Nov 1 - Nov 2

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

Novotel Santa Cruz De La Sierra

Santa Cruz

$119

$119 total

Nov 23 - Nov 24

A swimming pool with a fountain, surrounded by a deck and a building with a dome and bell tower.

A spacious living area with a black sofa, a glass coffee table, and a plant.

A room with a glass table and chair, a lamp, and a view of a brick building through large windows.

A hotel room with two beds, a red sofa, a desk, a television, and a city view through the window.

Hotel Pascana centro

Centro Histórico

$90

$90 total

Oct 26 - Oct 27

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Go beyond your typical stay in Santa Cruz

Pet friendly

Pool

Spa

Family friendly

Hot tub

Our prices for hotels in Santa Cruz are cheapest in February

Top neighborhoods in Santa Cruz

Equipetrol

Santa Cruz's Equipetrol neighborhood offers attractions including Santa Cruz Zoo.

Centro Histórico

Santa Cruz's Centro Histórico neighborhood is home to attractions such as Plaza 24 de Septiembre and La Recova Artisan Walk.

Hamacas

Zona Sur (South Zone)

Urubó

Top landmarks in Santa Cruz

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)

If you're planning a bit of sightseeing head to Plaza 24 de Septiembre— just one of the monuments in Centro Histórico.

A historic tower with a clock, surrounded by lush greenery and palm trees.

San Lorenzo Cathedral

9.0/10 (84 reviews)

Centro Histórico is home to San Lorenzo Cathedral, so why not stop by during your stay in Santa Cruz.

Ventura Mall

9.0/10 (183 reviews)

If you like shopping, take time out to go to Ventura Mall when in Santa Cruz.

Guembe Biocenter

8.8/10 (60 reviews)

Ready for an education in local botany? Guembe Biocenter should make your list of places to visit, located 1.2 mi (2 km) from central Colinas del Urubo. Want to stretch your legs some more? Head to Arenal Park, located nearby.

Santa Cruz Zoo

8.4/10 (53 reviews)

It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a trip to Santa Cruz Zoo, located 1.7 mi (2.8 km) from central Santa Cruz. If you have fun at Santa Cruz Zoo, you'll love Guembe Biocenter and Franco Aleman Cultural Center, both located nearby.

Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)

You can catch an event at Ramon Tahuichi Aguilera Stadium, located 0.8 mi (1.3 km) from central Santa Cruz.

Cine Center

8.0/10 (53 reviews)

Cine Center is 1 mi (1.6 km) from central Santa Cruz, why not stop by during your stay. If you enjoy the show and want to see another, Casa Municipal de Cultura Raúl Otero Reiche isn't far.

Blacutt Square

8.2/10 (19 reviews)

You might want to get your camera out and head to Blacutt Square— just one of the landmarks located 0.7 mi (1.1 km) from central Santa Cruz.

Learn more about Santa Cruz

Santa Cruz is applauded for its cultural attractions such as Ethno-folkloric Museum and Cine Center.

See all hotels in Santa Cruz

A historic cathedral with two prominent towers, surrounded by urban buildings and palm trees.

Check out reviews of Santa Cruz hotels guests love

Hotel Las Américas

Hotel Las Américas

8/10 Good

"Great place for the price. Only issue I had was the music blaring one of two nights across the street - all night, from 9pm to 6am. Not the hotels fault; but frustrating. Would stay again though"

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

10/10 Excellent

"Beautiful hotel. Spacious room. House cleaning came every day. We got new towels every day and toiletries in the bathroom were refilled every day. Staff were friendly. View from the breakfast room was beautiful. Location of the hotel is good."

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

10/10 Excellent

"Love staying there…. Very clean and staff always willing to assist."

Sun Hotel

Sun Hotel

10/10 Excellent

"Clean rooms, nice soft bed the shower water was warm not hot. The breakfast buffet was pretty good, omelets, cereal, fruit, ham, cheese pancakes, rolls and muffins etc. Airport transportation was there waiting(contact them ahead of your arrival) and available every hour to return."

Hotel Cortez

Hotel Cortez

10/10 Excellent

"El hotel es fantastico, el desayuno excelente, los servicios que brinda el hotel son un plus para el huésped. En general, el personal es atento y amable. Sin embargo, tuvimos problemas en el check in, la señorita que nos recibió indicó que no teníamos reservación. Se le indicó que la reservación se había hecho por Expedia y ella insistió en que no teníamos alguna. Cuando llamé a Expedia, nos dijo que, aunque el hotel estaba lleno, nos darían una habitación. Esta señorita parece no ser tan amable, lo cual es la excepción, pues el personal es atento y presto a ayudar al huésped."

Chairú Eco Hotel

Chairú Eco Hotel

8/10 Good

"The breakfast was not that good, but everything was good"

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

10/10 Excellent

"The room was very clean and the breakfast was fantastic. Overall it was a great experience."

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure

10/10 Excellent

"Todo muy bien"

Hotel LP Equipetrol

Hotel LP Equipetrol

8/10 Good

"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"

Frequently asked questions

What hotels do travelers recommend in Santa Cruz?

Guests like Ibis Santa Cruz DE LA Sierra, Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Marriott Santa Cruz de la Sierra Hotel.

Where can I find free parking at my hotel in Santa Cruz?

These hotels offer the perk of free parking: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Hotel LP Equipetrol and Hotel LP Santa Cruz Centro. There are 8 options you may want to check out on our site.

Can I book refundable hotels in Santa Cruz?

If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where should I consider staying in Santa Cruz if I'm looking for a reasonably priced accommodation?

An inexpensive option worth considering is Hotel LP Equipetrol. You can browse all 7 choices on our site.

Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?

If you want to find a good alternative to a hotel, browse our selection of 23 vacation homes. In addition, you can choose from 198 apartments.

What will the weather in Santa Cruz be like during my trip?

Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.

Why should I book my Santa Cruz accommodation with Hotels.com?

There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.