Hotels in Santa Cruz

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Oct 16 - Oct 18

Where to stay in Santa Cruz?

A modern lobby with seating areas, a coffee table, and a large potted plant.

A modern dining area with green chairs, a long table, and a wall with geometric patterns.

A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

1. Ibis Santa Cruz DE LA Sierra

Equipetrol

$39

$39 total

Oct 18 - Oct 19

A poolside area with lounge chairs and a palm tree.

A dining table with breakfast items and a pool view.

A modern hotel entrance with a curved canopy, large columns, and a well-lit facade.

A banquet hall with long tables, chandeliers, and draped curtains.

2. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Equipetrol

$151

$151 total

Nov 1 - Nov 2

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A spacious lobby with high ceilings, large windows, and a modern chandelier.

A restaurant with a long counter, dark chairs, and hanging lights.

A large, illuminated swimming pool surrounded by palm trees and pathways.

3. Camino Real Hotel

Santa Cruz

$161

$161 total

Oct 11 - Oct 12

A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

A luxurious banquet hall with ornate chandeliers, floral arrangements, and elegant table settings.

A modern lobby with a dining area, sofas, and a decorative wall.

A restaurant with a high ceiling, large windows, and a view of the cityscape. Tables are set with plates, glasses, and cutlery.

4. Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

$106

$106 total

Nov 1 - Nov 2

A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.

A hotel room with a large bed, a TV mounted on the wall, a dining area with chairs, and a sofa.

A modern staircase with glass railings, leading to a landing with a small garden area.

A modern lobby with wooden paneling, two grey sofas, and pendant lighting.

5. Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

$46

$46 total

Oct 9 - Oct 10

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.

A buffet with various fruits and snacks.

A sauna with wooden walls and benches.

6. Hotel Cortez

Equipetrol

$138

$138 total

Oct 10 - Oct 11

A modern restaurant with a city view, featuring glass tables, white chairs, and a large window with curtains.

A modern hotel lobby with a bar area, seating arrangements, and a television.

A small, enclosed garden area with various potted plants and a gravel path.

A hotel with a prominent 'Hampton' sign, large windows, and a modern facade.

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Santa Cruz

$74

$74 total

Oct 10 - Oct 11

A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

A modern hotel room with a cityscape view at sunset, a tufted headboard, and a neatly made bed with white linens and dark accents.

A reception area with a marble counter, a large chandelier, and a digital display.

A rooftop pool area with a view of the city skyline at dusk.

8. TRYP by Wyndham Santa Cruz

Equipetrol

$109

$109 total

Oct 5 - Oct 6

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

9. HOTEL OSHO

Santa Cruz

$47

$47 total

Oct 5 - Oct 6

A rooftop pool with a glass barrier reflecting the sunset and city skyline.

A hotel room with two beds, a desk, and a view of the city.

A buffet with various food items and a pitcher of orange juice.

An outdoor dining area with tables and chairs, a wooden pergola with hanging lights, and a city view.

10. Delfines Collection Hotel By Mercure

Equipetrol

$48

$48 total

Oct 18 - Oct 19

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

11. Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$107

$107 total

Oct 18 - Oct 19

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A window seat with a view of a cityscape at dusk.

12. Novotel Santa Cruz De La Sierra

Santa Cruz

$113

$113 total

Nov 1 - Nov 2

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A man in a suit entering an elevator.

A buffet setup with various food items and a serving area.

A hotel room with two beds, a desk, a television, and a small kitchenette.

13. Hotel Las Américas

Centro Histórico

$26

$26 total

Oct 5 - Oct 6

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

A staircase with ornate lion statues at the base, a chandelier, and a framed artwork on the wall.

A traditional-style room with a sofa set, a table, and two chairs.

A spacious restaurant with wooden flooring, tables with red and white tablecloths, and wicker chairs.

14. Lido Hotel

Centro Histórico

$25

$25 total

Oct 6 - Oct 7

A buffet setup with various food items and beverages.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

A corridor with wooden doors, orange walls, and a carpeted floor.

15. Hotel LP Equipetrol

Equipetrol

$45

$50 total

Nov 1 - Nov 2

A spacious room with a wooden floor and large windows offering a city view.

A buffet table with various food items and a wine bottle.

A hotel room with two beds, a nightstand, and a wall-mounted lamp.

Meeting facility

16. Swissôtel Santa Cruz De La Sierra

Santa Cruz

$131

$131 total

Oct 23 - Oct 24

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A room with a large window, a brick wall, and a hanging plant.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A multi-level atrium with a central planter containing various plants, surrounded by glass railings and a brick wall.

17. Chairú Eco Hotel

Santa Cruz

$47

$47 total

Nov 1 - Nov 2

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A table set for a meal with a view of a body of water and decorative lighting.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

18. Sun Hotel

Santa Cruz

$97

$97 total

Oct 17 - Oct 18

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A building with a sign that reads "COSMOPOLITANO."

A multi-level indoor space with a pool, wooden flooring, and potted plants.

19. Cosmopolitano Hotel Boutique

Centro Histórico

$58

$58 total

Oct 21 - Oct 22

An outdoor dining area with tables and chairs, surrounded by plants and palm trees.

A hotel room with a bed, a sofa, a coffee table, and a vase of flowers.

A residential street with modern buildings, parked cars, and palm trees.

A modern hotel with a swimming pool, lounge chairs, and a clear sky.

20. Terranova Suites

Santa Cruz

$52

$52 total

Oct 5 - Oct 6

View all properties

Get last-minute hotel deals in Santa Cruz and save more

Sign in to unlock great savings.

Next weekend
Next month

Reception

Room

Rooftop terrace

Room

Hotel Maywa

Santa Cruz

$10 off

$44

per night

$88 total

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A room with a large window, a brick wall, and a hanging plant.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A multi-level atrium with a central planter containing various plants, surrounded by glass railings and a brick wall.

Chairú Eco Hotel

Santa Cruz

$51 off

$49

per night

$99 total

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A building with a sign that reads "COSMOPOLITANO."

A multi-level indoor space with a pool, wooden flooring, and potted plants.

Cosmopolitano Hotel Boutique

Centro Histórico

$43 off

$65

per night

$130 total

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

A staircase with ornate lion statues at the base, a chandelier, and a framed artwork on the wall.

A traditional-style room with a sofa set, a table, and two chairs.

A spacious restaurant with wooden flooring, tables with red and white tablecloths, and wicker chairs.

Lido Hotel

Centro Histórico

$6 off

$25

per night

$51 total

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$105 off

$123

per night

$245 total

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A spacious lobby with high ceilings, large windows, and a modern chandelier.

A restaurant with a long counter, dark chairs, and hanging lights.

A large, illuminated swimming pool surrounded by palm trees and pathways.

Camino Real Hotel

Santa Cruz

$214

per night

$428 total

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

HOTEL OSHO

Santa Cruz

$22 off

$51

per night

$102 total

A modern lobby with seating areas, a coffee table, and a large potted plant.

A modern dining area with green chairs, a long table, and a wall with geometric patterns.

A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$73

per night

$145 total

A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

A balcony with two wooden chairs and a table, overlooking a cityscape with various buildings.

A reception desk with a wooden panel wall behind it, displaying the text "Premium Suites".

A dining area with a glass table, metal chairs, and a buffet setup. There is a red sofa in the living area and a kitchen in the background.

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

$6 off

$27

per night

$54 total

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A table set for a meal with a view of a body of water and decorative lighting.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

Sun Hotel

Santa Cruz

$44 off

$108

per night

$216 total

A swimming pool with three people sitting by the edge, one holding a drink.

A buffet setup with various food items and a person serving.

A person dining at an outdoor table by a pool with a fruit basket, bread, and a glass of orange juice.

A multi-story hotel with a modern facade, large windows, and a prominent sign at the top.

Hotel Continental Park

Centro Histórico

$69

per night

$138 total

A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.

A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.

A modern reception area with a grey reception desk labeled "hola. bienvenido".

A modern restaurant interior with high tables and chairs, a large window with a view of the city, and a mural of a pink cherry blossom tree.

Hotel LP Santa Cruz Centro

Santa Cruz

$49 off

$52

per night

$108 total

A buffet setup with various food items and beverages.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

A corridor with wooden doors, orange walls, and a carpeted floor.

Hotel LP Equipetrol

Equipetrol

$59

per night

$123 total

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A man in a suit entering an elevator.

A buffet setup with various food items and a serving area.

A hotel room with two beds, a desk, a television, and a small kitchenette.

Hotel Las Américas

Centro Histórico

$6 off

$26

per night

$52 total

A rooftop infinity pool with a clear view of the city skyline and a moon in the sky.

A balcony with a city view at dusk.

A modern kitchen with wooden cabinets, a dining table with a decorative table runner, and a view of the city through a large window.

A multi-story building with a sign for 'COMEDOR DOMINGO TAMISA III' indicating a hotel or lodging facility.

Mirador del Cielo

Santa Cruz

$7 off

$19

per night

$39 total

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A building with a sign that reads "COSMOPOLITANO."

A multi-level indoor space with a pool, wooden flooring, and potted plants.

Cosmopolitano Hotel Boutique

Centro Histórico

$19 off

$58

per night

$58 total

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A table set for a meal with a view of a body of water and decorative lighting.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

Sun Hotel

Santa Cruz

$22 off

$108

per night

$108 total

A modern lobby with seating areas, a coffee table, and a large potted plant.

A modern dining area with green chairs, a long table, and a wall with geometric patterns.

A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$50

per night

$50 total

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

A staircase with ornate lion statues at the base, a chandelier, and a framed artwork on the wall.

A traditional-style room with a sofa set, a table, and two chairs.

A spacious restaurant with wooden flooring, tables with red and white tablecloths, and wicker chairs.

Lido Hotel

Centro Histórico

$3 off

$25

per night

$25 total

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A room with a large window, a brick wall, and a hanging plant.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A multi-level atrium with a central planter containing various plants, surrounded by glass railings and a brick wall.

Chairú Eco Hotel

Santa Cruz

$31 off

$54

per night

$54 total

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$15 off

$134

per night

$134 total

Reception

Room

Rooftop terrace

Room

Hotel Maywa

Santa Cruz

$5 off

$44

per night

$44 total

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

HOTEL OSHO

Santa Cruz

$6 off

$56

per night

$56 total

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A spacious lobby with high ceilings, large windows, and a modern chandelier.

A restaurant with a long counter, dark chairs, and hanging lights.

A large, illuminated swimming pool surrounded by palm trees and pathways.

Camino Real Hotel

Santa Cruz

$189

per night

$189 total

A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

A balcony with two wooden chairs and a table, overlooking a cityscape with various buildings.

A reception desk with a wooden panel wall behind it, displaying the text "Premium Suites".

A dining area with a glass table, metal chairs, and a buffet setup. There is a red sofa in the living area and a kitchen in the background.

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

$3 off

$27

per night

$27 total

A swimming pool with three people sitting by the edge, one holding a drink.

A buffet setup with various food items and a person serving.

A person dining at an outdoor table by a pool with a fruit basket, bread, and a glass of orange juice.

A multi-story hotel with a modern facade, large windows, and a prominent sign at the top.

Hotel Continental Park

Centro Histórico

$69

per night

$69 total

A spacious lobby with a high ceiling, modern furniture, and a large chandelier.

A spacious, well-lit interior with a modern white sofa set, a glass coffee table, and a dining area with red tablecloths.

A modern interior with a white sofa, a dining area, and a staircase.

A breakfast table with plates of food, glasses of juice, and a cup of coffee.

Hotel Arenal

Centro Histórico

$10 off

$59

per night

$59 total

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

Hotel G

Santa Cruz

$12 off

$27

per night

$27 total

A buffet setup with various food items and beverages.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

A corridor with wooden doors, orange walls, and a carpeted floor.

Hotel LP Equipetrol

Equipetrol

$22 off

$52

per night

$57 total

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A window seat with a view of a cityscape at dusk.

Novotel Santa Cruz De La Sierra

Santa Cruz

$119

per night

$119 total

Hotels recommended for the best value in Santa Cruz

Get more from your budget at these hotels, based on amenities, reviews, and location

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

A staircase with ornate lion statues at the base, a chandelier, and a framed artwork on the wall.

A traditional-style room with a sofa set, a table, and two chairs.

A spacious restaurant with wooden flooring, tables with red and white tablecloths, and wicker chairs.

Lido Hotel

Centro Histórico

Free breakfast
Free parking
24/7 front desk

Travelers enjoy the well-priced location and comfortable rooms.

$25

$25 total

Oct 6 - Oct 7

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A man in a suit entering an elevator.

A buffet setup with various food items and a serving area.

A hotel room with two beds, a desk, a television, and a small kitchenette.

Hotel Las Américas

Centro Histórico

Free breakfast
24/7 front desk

An on-site restaurant and free breakfast help make the stay great value.

$26

$26 total

Oct 5 - Oct 6

A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.

A hotel room with a large bed, a TV mounted on the wall, a dining area with chairs, and a sofa.

A modern staircase with glass railings, leading to a landing with a small garden area.

A modern lobby with wooden paneling, two grey sofas, and pendant lighting.

Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

Free parking
Pool
Gym
Airport transfer

A fitness center and an outdoor pool make this a good-value stay.

$46

$46 total

Oct 9 - Oct 10

A modern lobby with seating areas, a coffee table, and a large potted plant.

A modern dining area with green chairs, a long table, and a wall with geometric patterns.

A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

Ibis Santa Cruz DE LA Sierra

Equipetrol

Free parking
Airport transfer
24/7 front desk

Travelers like the friendly staff and cleanliness at good value for money.

$39

$39 total

Oct 18 - Oct 19

A rooftop pool with a glass barrier reflecting the sunset and city skyline.

A hotel room with two beds, a desk, and a view of the city.

A buffet with various food items and a pitcher of orange juice.

An outdoor dining area with tables and chairs, a wooden pergola with hanging lights, and a city view.

Delfines Collection Hotel By Mercure

Equipetrol

Pool

Travelers say the pool and good breakfasts offer great value for money.

$48

$48 total

Oct 18 - Oct 19

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

HOTEL OSHO

Santa Cruz

Free breakfast
Pool
Gym
Airport transfer

With a fitness center, a spa and an outdoor pool, this is a good-value pick.

$47

$47 total

Oct 5 - Oct 6

An outdoor dining area with tables and chairs, surrounded by plants and palm trees.

A hotel room with a bed, a sofa, a coffee table, and a vase of flowers.

A residential street with modern buildings, parked cars, and palm trees.

A modern hotel with a swimming pool, lounge chairs, and a clear sky.

Terranova Suites

Santa Cruz

Free parking
Pool

Travelers love the great value of the breakfast and cleanliness.

$52

$52 total

Oct 5 - Oct 6

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A room with a large window, a brick wall, and a hanging plant.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A multi-level atrium with a central planter containing various plants, surrounded by glass railings and a brick wall.

Chairú Eco Hotel

Santa Cruz

24/7 front desk

Travelers appreciate the breakfast and service at good value for money.

$47

$47 total

Nov 1 - Nov 2

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A building with a sign that reads "COSMOPOLITANO."

A multi-level indoor space with a pool, wooden flooring, and potted plants.

Cosmopolitano Hotel Boutique

Centro Histórico

Free breakfast
Free parking
Pool
Airport transfer

Travelers appreciate that the dining and service offer good value.

$58

$58 total

Oct 21 - Oct 22

A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.

A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.

A modern reception area with a grey reception desk labeled "hola. bienvenido".

A modern restaurant interior with high tables and chairs, a large window with a view of the city, and a mural of a pink cherry blossom tree.

Hotel LP Santa Cruz Centro

Santa Cruz

Free parking
Airport transfer
24/7 front desk

Travelers appreciate the cleanliness and breakfast for good value.

$52

$57 total

Oct 21 - Oct 22

View all properties

Check out pet-friendly hotels in Santa Cruz

A modern lobby with seating areas, a coffee table, and a large potted plant.

A modern dining area with green chairs, a long table, and a wall with geometric patterns.

A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$39

$39 total

Oct 18 - Oct 19

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A building with a sign that reads "COSMOPOLITANO."

A multi-level indoor space with a pool, wooden flooring, and potted plants.

Cosmopolitano Hotel Boutique

Centro Histórico

$58

$58 total

Oct 21 - Oct 22

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

HOTEL OSHO

Santa Cruz

$47

$47 total

Oct 5 - Oct 6

An aerial view of a residential area with a swimming pool, a playground, and a large building with a red roof.

A gym with various exercise equipment, including a treadmill, weight machines, and a bench.

A hotel room with a bed, a desk with a chair, a television, and a window with a city view.

Gran Hotel Santa Cruz

Centro Histórico

$58

$58 total

Oct 9 - Oct 10

A hotel room with a round wooden table, two single beds, a red chair, and a wooden wall.

A compact kitchenette with a refrigerator, a coffee maker, and a small table with a laptop.

A swimming pool with a fountain, surrounded by a deck and a building with a dome and bell tower.

A hotel room with a bed, a desk with a computer and two remote controls, a window with a city view, and a wooden headboard.

Hotel Pascana centro

Centro Histórico

$54

$54 total

Oct 5 - Oct 6

A modern rooftop pool with a city view, wooden flooring, and a seating area.

A modern office space with a dark wood desk, a black office chair, a flat-screen TV mounted on the wall, and an air conditioning unit.

A modern kitchen with a built-in grill, a black countertop, and a wall mural of tropical leaves.

A modern living room with a sofa and a kitchen area featuring a microwave, kettle, and a coffee machine.

AMERICA APARTMENTS

Santa Cruz

$34

$34 total

Oct 5 - Oct 6

A modern hotel room with a bed, a nightstand, a lamp, a painting, a kitchen area, and a bathroom.

A compact kitchen with a stove, sink, and coffee maker. A bed with a blue pillow is visible in the background.

A modern kitchen with wooden cabinets, a black countertop, and a built-in stove.

A cozy seating area with a round wooden table, a white cup, and a book.

Equipetrol Suites Apart Hotel

Santa Cruz

$51

$51 total

Oct 5 - Oct 6

A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.

A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.

A modern reception area with a grey reception desk labeled "hola. bienvenido".

A modern restaurant interior with high tables and chairs, a large window with a view of the city, and a mural of a pink cherry blossom tree.

Hotel LP Santa Cruz Centro

Santa Cruz

$52

$57 total

Oct 21 - Oct 22

A buffet setup with various food items and beverages.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

A corridor with wooden doors, orange walls, and a carpeted floor.

Hotel LP Equipetrol

Equipetrol

$45

$50 total

Nov 1 - Nov 2

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

Hotel G

Santa Cruz

$27

$27 total

Nov 2 - Nov 3

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

View all properties

Go beyond your typical stay in Santa Cruz

Pet friendly

Pool

Spa

Family friendly

Hot tub

Our prices for hotels in Santa Cruz are cheapest in February

Top neighborhoods in Santa Cruz

Equipetrol

Santa Cruz's Equipetrol neighborhood offers attractions including Santa Cruz Zoo.

Centro Histórico

Santa Cruz's Centro Histórico neighborhood is home to attractions such as Plaza 24 de Septiembre and La Recova Artisan Walk.

Hamacas

Zona Sur (South Zone)

Urubó

Top landmarks in Santa Cruz

A park with agave plants, benches, and red flowers.

Plaza 24 de Septiembre

8.8/10 (164 reviews)

If you're planning a bit of sightseeing head to Plaza 24 de Septiembre— just one of the monuments in Centro Histórico.

A historic tower with a clock, surrounded by lush greenery and palm trees.

San Lorenzo Cathedral

9.0/10 (84 reviews)

Centro Histórico is home to San Lorenzo Cathedral, so why not stop by during your stay in Santa Cruz.

Ventura Mall

9.0/10 (183 reviews)

If you like shopping, take time out to go to Ventura Mall when in Santa Cruz.

Guembe Biocenter

8.8/10 (60 reviews)

Ready for an education in local botany? Guembe Biocenter should make your list of places to visit, located 1.2 mi (2 km) from central Colinas del Urubo. Want to stretch your legs some more? Head to Arenal Park, located nearby.

Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)

You can catch an event at Ramon Tahuichi Aguilera Stadium, located 0.8 mi (1.3 km) from central Santa Cruz.

Las Brisas Shopping Center

8.4/10 (40 reviews)

If you like shopping, take time out to go to Las Brisas Shopping Center when in Santa Cruz.

Santa Cruz Zoo

8.4/10 (53 reviews)

It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a trip to Santa Cruz Zoo, located 1.7 mi (2.8 km) from central Santa Cruz. If you have fun at Santa Cruz Zoo, you'll love Guembe Biocenter and Franco Aleman Cultural Center, both located nearby.

Blacutt Square

8.2/10 (19 reviews)

You might want to get your camera out and head to Blacutt Square— just one of the landmarks located 0.7 mi (1.1 km) from central Santa Cruz.

Learn more about Santa Cruz

Santa Cruz is applauded for its cultural attractions such as Ethno-folkloric Museum and Cine Center.

See all hotels in Santa Cruz

A historic church with two prominent towers, a plaza with people, and a sunset in the background.

Check out reviews of Santa Cruz hotels guests love

Chairú Eco Hotel

Chairú Eco Hotel

8/10 Good

"The breakfast was not that good, but everything was good"

Hotel Cortez

Hotel Cortez

8/10 Good

"Clean room but it was not fully ready for me when I arrived."

Sun Hotel

Sun Hotel

10/10 Excellent

"Very nice place to stay. Close to the airport with shuttle to the hotel."

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

10/10 Excellent

"The room was very clean and the breakfast was fantastic. Overall it was a great experience."

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

10/10 Excellent

"All around good price and location"

HOTEL OSHO

HOTEL OSHO

10/10 Excellent

"Good"

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure

10/10 Excellent

"Todo muy bien"

Hotel LP Equipetrol

Hotel LP Equipetrol

8/10 Good

"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

10/10 Excellent

"Great location."

Frequently asked questions

What hotels do travelers recommend in Santa Cruz?

Guests like Ibis Santa Cruz DE LA Sierra, Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Marriott Santa Cruz de la Sierra Hotel.

Where can I find free parking at my hotel in Santa Cruz?

These hotels offer the perk of free parking: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Hotel LP Equipetrol and Hotel LP Santa Cruz Centro. There are 8 options you may want to check out on our site.

Can I book refundable hotels in Santa Cruz?

If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where should I consider staying in Santa Cruz if I'm looking for a reasonably priced accommodation?

An inexpensive option worth considering is Hotel LP Equipetrol. You can browse all 7 choices on our site.

Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?

If you want to find a good alternative to a hotel, browse our selection of 23 vacation homes. In addition, you can choose from 198 apartments.

What will the weather in Santa Cruz be like during my trip?

Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.

Why should I book my Santa Cruz accommodation with Hotels.com?

There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.