Hotels in Santa Cruz

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Sep 24 - Sep 25

Tomorrow

Sep 25 - Sep 26

This weekend

Sep 25 - Sep 27

Next weekend

Where to stay in Santa Cruz?

A modern lobby with seating areas, a coffee table, and a large potted plant.

A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

A dessert on a plate with chocolate sauce and nuts, a guitar in the background.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

1. Ibis Santa Cruz DE LA Sierra

Equipetrol

$44

$44 total

Oct 16 - Oct 17

A poolside area with lounge chairs and a palm tree.

A modern hotel entrance with a curved canopy, large columns, and a well-lit facade.

A dining table with breakfast items and a pool view.

A pathway through a lush garden with various trees and shrubs.

2. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Equipetrol

$144

$144 total

Oct 11 - Oct 12

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A large, illuminated swimming pool surrounded by palm trees and pathways.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

A spacious lobby with high ceilings, large windows, and a modern chandelier.

3. Camino Real Hotel

Santa Cruz

$161

$161 total

Oct 11 - Oct 12

A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

A modern lobby with a curved staircase, seating area, and a large wooden bookshelf.

A luxurious banquet hall with ornate chandeliers, floral arrangements, and elegant table settings.

A modern lobby with a dining area, sofas, and a decorative wall.

4. Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

$106

$106 total

Oct 2 - Oct 3

A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.

A modern lobby with wooden paneling, two grey sofas, and pendant lighting.

A buffet setup with various food items, including pastries, a cake, and beverages.

A modern staircase with glass railings, leading to a landing with a small garden area.

5. Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

$46

$46 total

Sep 29 - Sep 30

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A sauna with wooden walls and benches.

A buffet with various fruits and snacks.

A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.

6. Hotel Cortez

Equipetrol

$130

$130 total

Oct 4 - Oct 5

A modern restaurant with a city view, featuring glass tables, white chairs, and a large window with curtains.

A small, enclosed garden area with various potted plants and a gravel path.

A modern hotel lobby with a bar area, seating arrangements, and a television.

A hotel room with a large bed, a desk, a chair, a telephone, and a view of the city through large windows.

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Santa Cruz

$74

$74 total

Oct 2 - Oct 3

A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

A modern lounge area with leather sofas, a coffee table, and a view of a green wall with plants.

A modern hotel room with a cityscape view at sunset, a tufted headboard, and a neatly made bed with white linens and dark accents.

A rooftop pool area with a view of the city skyline at dusk.

8. TRYP by Wyndham Santa Cruz

Equipetrol

$87

$87 total

Sep 27 - Sep 28

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

9. HOTEL OSHO

Santa Cruz

$47

$47 total

Oct 1 - Oct 2

A rooftop pool with a glass barrier reflecting the sunset and city skyline.

A buffet with various food items and a pitcher of orange juice.

An outdoor dining area with tables and chairs, a wooden pergola with hanging lights, and a city view.

A modern building with a stone facade and large windows. The name 'DEFINES COLLECTION' is prominently displayed on the building.

10. Delfines Collection Hotel By Mercure

Equipetrol

$48

$48 total

Oct 9 - Oct 10

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

11. Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$107

$107 total

Oct 15 - Oct 16

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

12. Novotel Santa Cruz De La Sierra

Santa Cruz

$118

$118 total

Sep 30 - Oct 1

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A hotel room with two beds, a desk, a television, and a small kitchenette.

A man in a suit entering an elevator.

A buffet setup with various food items and a serving area.

13. Hotel Las Américas

Centro Histórico

$26

$26 total

Sep 28 - Sep 29

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

Wicker furniture with cushions, potted plants, and a ceiling with lights.

A spacious restaurant with wooden flooring, tables with red and white tablecloths, and wicker chairs.

A traditional-style room with a sofa set, a table, and two chairs.

14. Lido Hotel

Centro Histórico

$25

$25 total

Sep 27 - Sep 28

A buffet setup with various food items and beverages.

A corridor with wooden doors, orange walls, and a carpeted floor.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

15. Hotel LP Equipetrol

Equipetrol

$48

$53 total

Oct 16 - Oct 17

A spacious room with a wooden floor and large windows offering a city view.

A modern gym with a treadmill, a glass table with fitness items, and a city view through large windows.

A buffet table with various food items and a wine bottle.

A modern lobby with a marble floor, a chandelier, and potted plants.

16. Swissôtel Santa Cruz De La Sierra

Santa Cruz

$131

$131 total

Oct 14 - Oct 15

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A spacious lobby with a brick accent wall, a seating area with a coffee table, and a view of the kitchen in the background.

A room with a large window, a brick wall, and a hanging plant.

17. Chairú Eco Hotel

Santa Cruz

$49

$49 total

Oct 1 - Oct 2

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A table set for a meal with a view of a body of water and decorative lighting.

18. Sun Hotel

Santa Cruz

$97

$97 total

Oct 7 - Oct 8

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

19. Cosmopolitano Hotel Boutique

Centro Histórico

$58

$58 total

Sep 29 - Sep 30

An outdoor dining area with tables and chairs, surrounded by plants and palm trees.

A modern hotel with a swimming pool, lounge chairs, and a clear sky.

A kitchen with granite countertops, wooden chairs, a microwave, and a window.

A hotel room with a bed, a sofa, a coffee table, and a vase of flowers.

20. Terranova Suites

Santa Cruz

$52

$52 total

Sep 26 - Sep 27

View all properties

Get last-minute hotel deals in Santa Cruz and save more

Sign in to unlock great savings.

Hotel Maywa

Santa Cruz

$10 off

$43

per night

$87 total

A modern lobby with seating areas, a coffee table, and a large potted plant.

A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

A dessert on a plate with chocolate sauce and nuts, a guitar in the background.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$77

per night

$153 total

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A hotel room with two beds, a desk, a television, and a small kitchenette.

A man in a suit entering an elevator.

A buffet setup with various food items and a serving area.

Hotel Las Américas

Centro Histórico

$14 off

$41

per night

$81 total

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A large, illuminated swimming pool surrounded by palm trees and pathways.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

A spacious lobby with high ceilings, large windows, and a modern chandelier.

Camino Real Hotel

Santa Cruz

$396 off

$220

per night

$440 total

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

Novotel Santa Cruz De La Sierra

Santa Cruz

$130

per night

$259 total

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$12 off

$56

per night

$112 total

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$126 off

$112

per night

$224 total

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

Hotel G

Santa Cruz

$21 off

$41

per night

$82 total

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A table set for a meal with a view of a body of water and decorative lighting.

Sun Hotel

Santa Cruz

$85 off

$87

per night

$175 total

A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.

A hotel entrance with glass doors, a sign reading "LP HOTELES", and a green wall.

A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.

A modern restaurant interior with high tables and chairs, a large window with a view of the city, and a mural of a pink cherry blossom tree.

Hotel LP Santa Cruz Centro

Santa Cruz

$61 off

$64

per night

$134 total

A buffet setup with various food items and beverages.

A corridor with wooden doors, orange walls, and a carpeted floor.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

Hotel LP Equipetrol

Equipetrol

$40 off

$80

per night

$166 total

A spacious lobby with a high ceiling, modern furniture, and a large chandelier.

A rooftop bar with a pool, lounge chairs, and a city view.

A modern interior with a white sofa, a dining area, and a staircase.

A breakfast table with plates of food, glasses of juice, and a cup of coffee.

Hotel Arenal

Centro Histórico

$21 off

$59

per night

$119 total

Prince Hotel

Santa Cruz

$19 off

$44

per night

$93 total

A rooftop infinity pool with a clear view of the city skyline and a moon in the sky.

A modern kitchen with wooden cabinets, a dining table with a decorative table runner, and a view of the city through a large window.

A multi-story building with a sign for 'COMEDOR DOMINGO TAMISA III' indicating a hotel or lodging facility.

A gym with treadmills, a stationary bike, and various weight machines.

Mirador del Cielo

Santa Cruz

$7 off

$19

per night

$39 total

A spacious room with a wooden floor and large windows offering a city view.

A modern gym with a treadmill, a glass table with fitness items, and a city view through large windows.

A buffet table with various food items and a wine bottle.

A modern lobby with a marble floor, a chandelier, and potted plants.

Swissôtel Santa Cruz De La Sierra

Santa Cruz

$185

per night

$369 total

Hotel Maywa

Santa Cruz

$10 off

$43

per night

$87 total

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A spacious lobby with a brick accent wall, a seating area with a coffee table, and a view of the kitchen in the background.

A room with a large window, a brick wall, and a hanging plant.

Chairú Eco Hotel

Santa Cruz

$51 off

$49

per night

$99 total

A modern lobby with seating areas, a coffee table, and a large potted plant.

A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

A dessert on a plate with chocolate sauce and nuts, a guitar in the background.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$46

per night

$92 total

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

Wicker furniture with cushions, potted plants, and a ceiling with lights.

A spacious restaurant with wooden flooring, tables with red and white tablecloths, and wicker chairs.

A traditional-style room with a sofa set, a table, and two chairs.

Lido Hotel

Centro Histórico

$5 off

$25

per night

$49 total

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A large, illuminated swimming pool surrounded by palm trees and pathways.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

A spacious lobby with high ceilings, large windows, and a modern chandelier.

Camino Real Hotel

Santa Cruz

$226 off

$159

per night

$318 total

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

Cosmopolitano Hotel Boutique

Centro Histórico

$51 off

$77

per night

$154 total

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A hotel room with two beds, a desk, a television, and a small kitchenette.

A man in a suit entering an elevator.

A buffet setup with various food items and a serving area.

Hotel Las Américas

Centro Histórico

$8 off

$22

per night

$44 total

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

Novotel Santa Cruz De La Sierra

Santa Cruz

$116

per night

$232 total

A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

A balcony with two wooden chairs and a table, overlooking a cityscape with various buildings.

A group of women standing in a modern interior with wooden paneling and a reception desk.

A dining area with a glass table, metal chairs, and a buffet setup. There is a red sofa in the living area and a kitchen in the background.

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

$6 off

$27

per night

$54 total

A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.

A hotel entrance with glass doors, a sign reading "LP HOTELES", and a green wall.

A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.

A modern restaurant interior with high tables and chairs, a large window with a view of the city, and a mural of a pink cherry blossom tree.

Hotel LP Santa Cruz Centro

Santa Cruz

$51 off

$50

per night

$106 total

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$45 off

$52

per night

$105 total

A buffet setup with various food items and beverages.

A corridor with wooden doors, orange walls, and a carpeted floor.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

Hotel LP Equipetrol

Equipetrol

$51

per night

$107 total

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$128 off

$111

per night

$222 total

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

Hotel G

Santa Cruz

$16 off

$31

per night

$62 total

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A table set for a meal with a view of a body of water and decorative lighting.

Sun Hotel

Santa Cruz

$85 off

$87

per night

$175 total

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

Cosmopolitano Hotel Boutique

Centro Histórico

$21 off

$62

per night

$62 total

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A spacious lobby with a brick accent wall, a seating area with a coffee table, and a view of the kitchen in the background.

A room with a large window, a brick wall, and a hanging plant.

Chairú Eco Hotel

Santa Cruz

$26 off

$49

per night

$49 total

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

Wicker furniture with cushions, potted plants, and a ceiling with lights.

A spacious restaurant with wooden flooring, tables with red and white tablecloths, and wicker chairs.

A traditional-style room with a sofa set, a table, and two chairs.

Lido Hotel

Centro Histórico

$3 off

$25

per night

$25 total

Hotel Maywa

Santa Cruz

$5 off

$43

per night

$43 total

A modern lobby with seating areas, a coffee table, and a large potted plant.

A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

A dessert on a plate with chocolate sauce and nuts, a guitar in the background.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$44

per night

$44 total

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$78 off

$97

per night

$97 total

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A table set for a meal with a view of a body of water and decorative lighting.

Sun Hotel

Santa Cruz

$33 off

$97

per night

$97 total

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A sauna with wooden walls and benches.

A buffet with various fruits and snacks.

A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.

Hotel Cortez

Equipetrol

$130

per night

$130 total

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$24 off

$41

per night

$56 total

A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

A balcony with two wooden chairs and a table, overlooking a cityscape with various buildings.

A group of women standing in a modern interior with wooden paneling and a reception desk.

A dining area with a glass table, metal chairs, and a buffet setup. There is a red sofa in the living area and a kitchen in the background.

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

$3 off

$27

per night

$27 total

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A hotel room with two beds, a desk, a television, and a small kitchenette.

A man in a suit entering an elevator.

A buffet setup with various food items and a serving area.

Hotel Las Américas

Centro Histórico

$4 off

$25

per night

$25 total

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

Novotel Santa Cruz De La Sierra

Santa Cruz

$119

per night

$119 total

A spacious room with a wooden floor and large windows offering a city view.

A modern gym with a treadmill, a glass table with fitness items, and a city view through large windows.

A buffet table with various food items and a wine bottle.

A modern lobby with a marble floor, a chandelier, and potted plants.

Swissôtel Santa Cruz De La Sierra

Santa Cruz

$131

per night

$131 total

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A large, illuminated swimming pool surrounded by palm trees and pathways.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

A spacious lobby with high ceilings, large windows, and a modern chandelier.

Camino Real Hotel

Santa Cruz

$225

per night

$225 total

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

Hotel G

Santa Cruz

$12 off

$27

per night

$27 total

Check out pet-friendly hotels in Santa Cruz

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern kitchen with a wooden countertop, various appliances, and a dining area with chairs and a table.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

Hotel G

Santa Cruz

$27

$27 total

Oct 23 - Oct 24

A modern lobby with seating areas, a coffee table, and a large potted plant.

A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

A dessert on a plate with chocolate sauce and nuts, a guitar in the background.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$44

$44 total

Oct 16 - Oct 17

A hotel room with a large bed, a desk with a computer, a chair, and a painting on the wall.

A compact kitchenette with a refrigerator, a coffee maker, and a small table with a laptop.

A modern interior with a dining area, kitchen, and large windows.

A modern interior with a black leather sofa, a glass coffee table with a vase, and a brick wall.

Hotel Pascana centro

Centro Histórico

$54

$54 total

Sep 28 - Sep 29

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$47

$47 total

Oct 1 - Oct 2

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

Cosmopolitano Hotel Boutique

Centro Histórico

$58

$58 total

Sep 29 - Sep 30

A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.

A hotel entrance with glass doors, a sign reading "LP HOTELES", and a green wall.

A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.

A modern restaurant interior with high tables and chairs, a large window with a view of the city, and a mural of a pink cherry blossom tree.

Hotel LP Santa Cruz Centro

Santa Cruz

$47

$52 total

Oct 6 - Oct 7

A buffet setup with various food items and beverages.

A corridor with wooden doors, orange walls, and a carpeted floor.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

Hotel LP Equipetrol

Equipetrol

$48

$53 total

Oct 16 - Oct 17

A modern hotel room with a bed, a nightstand, a lamp, a painting, a kitchen area, and a bathroom.

A compact kitchen with a stove, sink, and coffee maker. A bed with a blue pillow is visible in the background.

A modern kitchen with wooden cabinets, a black countertop, and a built-in stove.

A cozy seating area with a round wooden table, a white cup, and a book.

Equipetrol Suites Apart Hotel

Santa Cruz

$51

$51 total

Sep 25 - Sep 26

A modern rooftop pool with a city view, wooden flooring, and a seating area.

A modern kitchen with a built-in grill, a black countertop, and a wall mural of tropical leaves.

A modern office space with a dark wood desk, a black office chair, a flat-screen TV mounted on the wall, and an air conditioning unit.

A modern living room with a sofa and a kitchen area featuring a microwave, kettle, and a coffee machine.

AMERICA APARTMENTS

Santa Cruz

$34

$34 total

Oct 3 - Oct 4

A spacious room with a wooden floor and large windows offering a city view.

A modern gym with a treadmill, a glass table with fitness items, and a city view through large windows.

A buffet table with various food items and a wine bottle.

A modern lobby with a marble floor, a chandelier, and potted plants.

Swissôtel Santa Cruz De La Sierra

Santa Cruz

$131

$131 total

Oct 14 - Oct 15

View all properties

You may also like hotels with pools in Santa Cruz

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A sauna with wooden walls and benches.

A buffet with various fruits and snacks.

A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.

Hotel Cortez

Equipetrol

$130

$130 total

Oct 4 - Oct 5

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A table set for a meal with a view of a body of water and decorative lighting.

Sun Hotel

Santa Cruz

$97

$97 total

Oct 7 - Oct 8

A poolside area with lounge chairs and a palm tree.

A modern hotel entrance with a curved canopy, large columns, and a well-lit facade.

A dining table with breakfast items and a pool view.

A pathway through a lush garden with various trees and shrubs.

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Equipetrol

$144

$144 total

Oct 11 - Oct 12

A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.

A modern lobby with wooden paneling, two grey sofas, and pendant lighting.

A buffet setup with various food items, including pastries, a cake, and beverages.

A modern staircase with glass railings, leading to a landing with a small garden area.

Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

$46

$46 total

Sep 29 - Sep 30

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A large, illuminated swimming pool surrounded by palm trees and pathways.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

A spacious lobby with high ceilings, large windows, and a modern chandelier.

Camino Real Hotel

Santa Cruz

$161

$161 total

Oct 11 - Oct 12

A hotel room with a large bed, a desk with a computer, a chair, and a painting on the wall.

A compact kitchenette with a refrigerator, a coffee maker, and a small table with a laptop.

A modern interior with a dining area, kitchen, and large windows.

A modern interior with a black leather sofa, a glass coffee table with a vase, and a brick wall.

Hotel Pascana centro

Centro Histórico

$54

$54 total

Sep 28 - Sep 29

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$47

$47 total

Oct 1 - Oct 2

A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

A modern lounge area with leather sofas, a coffee table, and a view of a green wall with plants.

A modern hotel room with a cityscape view at sunset, a tufted headboard, and a neatly made bed with white linens and dark accents.

A rooftop pool area with a view of the city skyline at dusk.

TRYP by Wyndham Santa Cruz

Equipetrol

$87

$87 total

Sep 27 - Sep 28

A rooftop infinity pool with a clear view of the city skyline and a moon in the sky.

A modern kitchen with wooden cabinets, a dining table with a decorative table runner, and a view of the city through a large window.

A multi-story building with a sign for 'COMEDOR DOMINGO TAMISA III' indicating a hotel or lodging facility.

A gym with treadmills, a stationary bike, and various weight machines.

Mirador del Cielo

Santa Cruz

$23

$23 total

Sep 25 - Sep 26

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

Novotel Santa Cruz De La Sierra

Santa Cruz

$118

$118 total

Sep 30 - Oct 1

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

View all properties

Go beyond your typical stay in Santa Cruz

Pet friendly

Pool

Spa

Hot tub

Family friendly

Our prices for hotels in Santa Cruz are cheapest in February

Top neighborhoods in Santa Cruz

Equipetrol

Santa Cruz's Equipetrol neighborhood offers attractions including Santa Cruz Zoo.

Centro Histórico

Santa Cruz's Centro Histórico neighborhood is home to attractions such as Plaza 24 de Septiembre and La Recova Artisan Walk.

Hamacas

Zona Sur (South Zone)

Urubó

Top landmarks in Santa Cruz

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)

If you're planning a bit of sightseeing head to Plaza 24 de Septiembre— just one of the monuments in Centro Histórico.

An interior of a church with high arched ceilings, wooden pews, and a central altar.

San Lorenzo Cathedral

9.0/10 (84 reviews)

Centro Histórico is home to San Lorenzo Cathedral, so why not stop by during your stay in Santa Cruz.

Ventura Mall

9.0/10 (183 reviews)

If you like shopping, take time out to go to Ventura Mall when in Santa Cruz.

Guembe Biocenter

8.8/10 (60 reviews)

Ready for an education in local botany? Guembe Biocenter should make your list of places to visit, located 1.2 mi (2 km) from central Colinas del Urubo. Want to stretch your legs some more? Head to Arenal Park, located nearby.

Santa Cruz Zoo

8.4/10 (53 reviews)

It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a trip to Santa Cruz Zoo, located 1.7 mi (2.8 km) from central Santa Cruz. If you have fun at Santa Cruz Zoo, you'll love Guembe Biocenter and Artecampo, both located nearby.

Las Brisas Shopping Center

8.4/10 (40 reviews)

If you like shopping, take time out to go to Las Brisas Shopping Center when in Santa Cruz.

Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)

You can catch an event at Ramon Tahuichi Aguilera Stadium, located 0.8 mi (1.3 km) from central Santa Cruz.

Arenal Park

7.4/10 (16 reviews)

Arenal Park is worth a pic or two when discovering Centro Histórico.

Learn more about Santa Cruz

Santa Cruz is applauded for its cultural attractions such as Ethno-folkloric Museum and Cine Center.

See all hotels in Santa Cruz

A colonial-style building with a bell tower, palm trees, and a paved walkway.

Check out reviews of Santa Cruz hotels guests love

Hotel Cortez

Hotel Cortez

8/10 Good

"Clean room but it was not fully ready for me when I arrived."

Sun Hotel

Sun Hotel

10/10 Excellent

"Very nice place to stay. Close to the airport with shuttle to the hotel."

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

10/10 Excellent

"We had a great stay here. The rooms were clean and comfortable. Will return!"

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

10/10 Excellent

"The room was very clean and the breakfast was fantastic. Overall it was a great experience."

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

10/10 Excellent

"All around good price and location"

HOTEL OSHO

HOTEL OSHO

10/10 Excellent

"Good"

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure

10/10 Excellent

"Todo muy bien"

Hotel LP Equipetrol

Hotel LP Equipetrol

8/10 Good

"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

10/10 Excellent

"Great location."

Frequently asked questions

What hotels do travelers recommend in Santa Cruz?

Guests like Ibis Santa Cruz DE LA Sierra, Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Marriott Santa Cruz de la Sierra Hotel.

Where can I find free parking at my hotel in Santa Cruz?

These hotels offer the perk of free parking: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Hotel LP Equipetrol and Hotel LP Santa Cruz Centro. There are 8 options you may want to check out on our site.

Can I book refundable hotels in Santa Cruz?

If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where should I consider staying in Santa Cruz if I'm looking for a reasonably priced accommodation?

An inexpensive option worth considering is Hotel LP Equipetrol. You can browse all 7 choices on our site.

Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?

If you want to find a good alternative to a hotel, browse our selection of 23 vacation homes. In addition, you can choose from 198 apartments.

What will the weather in Santa Cruz be like during my trip?

Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.

Why should I book my Santa Cruz accommodation with Hotels.com?

There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.