Hotels in Santa Cruz
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Aug 13 - Aug 14Tomorrow
Aug 14 - Aug 15This weekend
Aug 14 - Aug 16Next weekend
Aug 21 - Aug 23Where to stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra
Ibis Santa Cruz DE LA SierraSanta Cruz
$34
$34 total
Aug 28 - Aug 29
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelSanta Cruz
$127
$127 total
Aug 23 - Aug 24
Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra HotelSanta Cruz
$106
$106 total
Aug 21 - Aug 22
Premium Suites Deluxe Aparthotel Equipetrol
Premium Suites Deluxe Aparthotel EquipetrolSanta Cruz
$35
$40 total
Aug 27 - Aug 28
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol, BoliviaSanta Cruz
$74
$74 total
Aug 27 - Aug 28
Delfines Collection Hotel By Mercure
Delfines Collection Hotel By MercureSanta Cruz
$48
$48 total
Aug 28 - Aug 29
TRYP by Wyndham Santa Cruz
TRYP by Wyndham Santa CruzSanta Cruz
$98
$98 total
Aug 15 - Aug 16
Novotel Santa Cruz De La Sierra
Novotel Santa Cruz De La SierraSanta Cruz
$119
$119 total
Aug 28 - Aug 29
Alfonsina Hotel Boutique by Inboccaluppo
Alfonsina Hotel Boutique by InboccaluppoSanta Cruz
$108
$108 total
Aug 17 - Aug 18
Swissôtel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La SierraSanta Cruz
$148
$148 total
Aug 28 - Aug 29
Cosmopolitano Hotel Boutique
Cosmopolitano Hotel BoutiqueSanta Cruz
$55
$55 total
Aug 18 - Aug 19
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$33 off
TRYP by Wyndham Santa Cruz$93
per night
$185 total
$184
per night
$369 total
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$132 off
Alfonsina Hotel Boutique by Inboccaluppo$109
per night
$218 total
$87 off
Hotel LP Santa Cruz Centro$40
per night
$85 total
$69
per night
$138 total
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$36 off
Hotel BY Armonia SCZ$77
per night
$153 total
$38
per night
$75 total
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$171
per night
$342 total
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$33 off
TRYP by Wyndham Santa Cruz$93
per night
$185 total
$134 off
Alfonsina Hotel Boutique by Inboccaluppo$108
per night
$216 total
$159
per night
$317 total
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$52 off
Cosmopolitano Hotel Boutique$93
per night
$186 total
$79 off
Hotel LP Santa Cruz Centro$36
per night
$78 total
$6 off
Apart Hotel Premium Suites Santa Cruz$27
per night
$54 total
$36
per night
$36 total
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$15 off
Cosmopolitano Hotel Boutique$60
per night
$60 total
$162
per night
$162 total
Sign in for extra savings
$119
per night
$119 total
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$11 off
TRYP by Wyndham Santa Cruz$98
per night
$98 total
$15 off
Alfonsina Hotel Boutique by Inboccaluppo$134
per night
$134 total
$39 off
Hotel LP Santa Cruz Centro$36
per night
$41 total
$3 off
Apart Hotel Premium Suites Santa Cruz$27
per night
$27 total
Check out pet-friendly hotels in Santa Cruz
$34
$34 total
Aug 28 - Aug 29
$55
$55 total
Aug 18 - Aug 19
$36
$41 total
Aug 16 - Aug 17
$50
$50 total
Aug 15 - Aug 16
$148
$148 total
Aug 28 - Aug 29
You can also stay at hotels with a pool in Santa Cruz
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelSanta Cruz
$127
$127 total
Aug 23 - Aug 24
$106
$106 total
Aug 21 - Aug 22
$35
$40 total
Aug 27 - Aug 28
$98
$98 total
Aug 15 - Aug 16
$119
$119 total
Aug 28 - Aug 29
$108
$108 total
Aug 17 - Aug 18
$55
$55 total
Aug 18 - Aug 19
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Santa Cruz
Pet friendly
Family friendly
Our prices for hotels in Santa Cruz are cheapest in February
Our prices for hotels in Santa Cruz are cheapest in February
Price trends for hotels in Santa Cruz
Pricing is based on two traveler single night rates
Top neighborhoods in Santa Cruz
Top landmarks in Santa Cruz
Plaza 24 de Septiembre
8.8/10 (164 reviews)
If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre— just one of the monuments in central Santa Cruz.
San Lorenzo Cathedral
9.0/10 (84 reviews)
San Lorenzo Cathedral is in the heart of Santa Cruz, so why not stop by during your stay.
Ventura Mall
9.0/10 (183 reviews)
If you like shopping, take time out to go to Ventura Mall when in Santa Cruz.
Guembe Biocenter
8.8/10 (60 reviews)
Ready for an education in local botany? Guembe Biocenter should make your list of places to visit, located 1.2 mi (2 km) from central Colinas del Urubo. Want to stretch your legs some more? Head to Arenal Park, located nearby.
Santa Cruz Zoo
8.4/10 (53 reviews)
It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a trip to Santa Cruz Zoo, located 1.7 mi (2.8 km) from central Santa Cruz. If you have fun at Santa Cruz Zoo, you'll love Guembe Biocenter and Artecampo, both located nearby.
Cine Center
8.0/10 (53 reviews)
Cine Center is 1 mi (1.6 km) from central Santa Cruz, why not stop by during your stay. If you enjoy the show and want to see another, Casa Municipal de Cultura Raúl Otero Reiche isn't far.
Ramon Tahuichi Aguilera Stadium
8.4/10 (18 reviews)
You can catch an event at Ramon Tahuichi Aguilera Stadium, located 0.8 mi (1.3 km) from central Santa Cruz.
Lomas de Arena Regional Park
8.4/10 (28 reviews)
Commune with nature and explore Lomas de Arena Regional Park located 10.7 mi (17.1 km) from central Santa Cruz.
Learn more about Santa Cruz
Santa Cruz is applauded for its cultural attractions such as Cine Center and Ethno-folkloric Museum.
See all hotels in Santa Cruz
Check out reviews of Santa Cruz hotels guests love
Ibis Santa Cruz DE LA Sierra
10/10 Excellent
"Excelente espacio Muy amable el personal"
Marriott Santa Cruz de la Sierra Hotel
10/10 Excellent
"I have come across the best Marriott experience on earth. The customer service was inexplicable. It was incredible. I was treated like a President. The staff were friendly, professional, and most welcoming. I seriously cannot find words to describe the experience. I would like to go back to Santa Cruz, Bolivia only because of the awesome experience at the Marriott Santa Cruz de la Sierra. I have stayed at numerous Marriott hotels in the US and in different countries; I have never felt like this before. The experience has never gone so deep. I have had by far, the best experience with any Marriott hotels. In addition, the hotel was so perfectly kept. It was a Wow!"
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
10/10 Excellent
"Como siempre el Mejor nivel para estancias en Santa Cruz"
Sun Hotel
10/10 Excellent
"El mejor servicio cerca del aeropuerto de Viru Viru"
Premium Suites Deluxe Aparthotel Equipetrol
10/10 Excellent
"great place to stay!"
Hotel Cortez
10/10 Excellent
"Very good."
Hotel LP Equipetrol
8/10 Good
"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"
Alfonsina Hotel Boutique by Inboccaluppo
10/10 Excellent
"Good hotel. Very contemporary; buffet breakfast included. We walked to the old part of the city/cathedral - probably about 40 minutes walk but can stop for a coffee along the way! Restaurant and bar in hotel. Hotel also close to many other restaurants/bars"
Delfines Collection Hotel By Mercure
10/10 Excellent
"Great location, nice and quiet neighborhood."