Hotels in Santa Cruz
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Aug 30 - Aug 31Tomorrow
Aug 31 - Sep 1Next weekend
Sep 4 - Sep 6In two weeks
Sep 11 - Sep 13Where to stay in Santa Cruz?




Ibis Santa Cruz DE LA Sierra
Ibis Santa Cruz DE LA SierraSanta Cruz
$36
$36 total
Sep 15 - Sep 16




Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelSanta Cruz
$135
$135 total
Sep 3 - Sep 4




Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra HotelSanta Cruz
$119
$119 total
Sep 12 - Sep 13




Premium Suites Deluxe Aparthotel Equipetrol
Premium Suites Deluxe Aparthotel EquipetrolSanta Cruz
$46
$46 total
Sep 7 - Sep 8




Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol, BoliviaSanta Cruz
$74
$74 total
Oct 1 - Oct 2




Delfines Collection Hotel By Mercure
Delfines Collection Hotel By MercureSanta Cruz
$50
$50 total
Sep 3 - Sep 4




TRYP by Wyndham Santa Cruz
TRYP by Wyndham Santa CruzSanta Cruz
$109
$109 total
Sep 1 - Sep 2




Novotel Santa Cruz De La Sierra
Novotel Santa Cruz De La SierraSanta Cruz
$119
$119 total
Sep 29 - Sep 30




Alfonsina Hotel Boutique by Inboccaluppo
Alfonsina Hotel Boutique by InboccaluppoSanta Cruz
$108
$108 total
Sep 4 - Sep 5




Swissôtel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La SierraSanta Cruz
$164
$164 total
Sep 14 - Sep 15




Cosmopolitano Hotel Boutique
Cosmopolitano Hotel BoutiqueSanta Cruz
$59
$59 total
Sep 5 - Sep 6
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$137
per night
$275 total
Sign in for extra savings
$58 off
Marriott Santa Cruz de la Sierra Hotel$165
per night
$330 total
$38 off
Hotel LP Santa Cruz Centro$40
per night
$85 total
$6 off
Apart Hotel Premium Suites Santa Cruz$27
per night
$54 total
$30 off
Alfonsina Hotel Boutique by Inboccaluppo$134
per night
$268 total
$36
per night
$36 total
Sign in for extra savings
$119
per night
$119 total
Sign in for extra savings
$15 off
Cosmopolitano Hotel Boutique$60
per night
$60 total
$203
per night
$203 total
Sign in for extra savings
$67 off
Alfonsina Hotel Boutique by Inboccaluppo$108
per night
$108 total
$3 off
Apart Hotel Premium Suites Santa Cruz$27
per night
$27 total
Check out pet-friendly hotels in Santa Cruz
$36
$36 total
Sep 15 - Sep 16
$41
$46 total
Sep 17 - Sep 18
$59
$59 total
Sep 5 - Sep 6
$50
$50 total
Sep 1 - Sep 2
You can also stay at hotels with a pool in Santa Cruz




Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelSanta Cruz
$135
$135 total
Sep 3 - Sep 4
$119
$119 total
Sep 29 - Sep 30
$119
$119 total
Sep 12 - Sep 13
$59
$59 total
Sep 5 - Sep 6
$46
$46 total
Sep 7 - Sep 8
$50
$50 total
Sep 3 - Sep 4
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Santa Cruz
Pet friendly
Family friendly
Our prices for hotels in Santa Cruz are cheapest in February
Our prices for hotels in Santa Cruz are cheapest in February
Price trends for hotels in Santa Cruz
Pricing is based on two traveler single night rates
Top neighborhoods in Santa Cruz
Top landmarks in Santa Cruz

Plaza 24 de Septiembre
8.8/10 (164 reviews)
If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre— just one of the monuments in central Santa Cruz.

San Lorenzo Cathedral
9.0/10 (84 reviews)
San Lorenzo Cathedral is in the heart of Santa Cruz, so why not stop by during your stay.
Ventura Mall
9.0/10 (183 reviews)
If you like shopping, take time out to go to Ventura Mall when in Santa Cruz.
Guembe Biocenter
8.8/10 (60 reviews)
Ready for an education in local botany? Guembe Biocenter should make your list of places to visit, located 1.2 mi (2 km) from central Colinas del Urubo. Want to stretch your legs some more? Head to Arenal Park, located nearby.
Santa Cruz Zoo
8.4/10 (53 reviews)
It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a trip to Santa Cruz Zoo, located 1.7 mi (2.8 km) from central Santa Cruz. If you have fun at Santa Cruz Zoo, you'll love Guembe Biocenter and Artecampo, both located nearby.
Cine Center
8.0/10 (53 reviews)
Cine Center is 1 mi (1.6 km) from central Santa Cruz, why not stop by during your stay. If you enjoy the show and want to see another, Casa Municipal de Cultura Raúl Otero Reiche isn't far.
Ramon Tahuichi Aguilera Stadium
8.4/10 (18 reviews)
You can catch an event at Ramon Tahuichi Aguilera Stadium, located 0.8 mi (1.3 km) from central Santa Cruz.
Las Brisas Shopping Center
8.4/10 (40 reviews)
If you like shopping, take time out to go to Las Brisas Shopping Center when in Santa Cruz.
Learn more about Santa Cruz
Santa Cruz is applauded for its cultural attractions such as Cine Center and Ethno-folkloric Museum.
See all hotels in Santa Cruz
Check out reviews of Santa Cruz hotels guests love
Sun Hotel
8/10 Good
"The room was clean and the AC worked great. I also enjoyed having good hot water. I was very happy that the room had a king bed instead of two double beds we received when we stayed here earlier in the week. The free shuttle wasn't available, so we had to take a taxi from the airport, but the front desk reimbursed us. I have to say that the front desk staff was not cordial, almost to the point of being unfriendly. This is sad. When we checked in I told the staff that the following night we needed to leave the hotel at 9 pm for the airport. The next day I also confirmed this. However, at 9 pm the shuttle was gone, to wait for an arrival. After 15 minutes, I asked again, and they finally ordered the shuttle to return and take us to the airport. This really cut down our available time at the airport. If Sun Hotel is going to be hostile to foreign visitors, then they shouldn't be in business where they are uniquely positioned 5 minutes from an international airport. Shame on you! And it wasn't a case of a difficult foreigner ... I speak fluent Spanish and was very polite in all our dealings."
Novotel Santa Cruz De La Sierra
10/10 Excellent
"All around good price and location"
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
10/10 Excellent
"Las piscinas son buenazas, la comida también, súper bien ubicado. Pero hay una zona que no tiene ascensor si te toca cuarto ahí y tienes silla de ruedas avisar"
Marriott Santa Cruz de la Sierra Hotel
10/10 Excellent
"Staff was super as well as how clean the room was."
Ibis Santa Cruz DE LA Sierra
10/10 Excellent
"Buen hotel Limpio y comodo"
Delfines Collection Hotel By Mercure
10/10 Excellent
"Todo muy bien"
Hotel LP Equipetrol
8/10 Good
"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"
Apart Hotel Premium Suites Santa Cruz
10/10 Excellent
"Great location."








































































































































