Hotels in Santa Cruz

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Check prices for these dates

Tonight

Oct 16 - Oct 17

Tomorrow

Oct 17 - Oct 18

This weekend

Oct 16 - Oct 18

Next weekend

Oct 23 - Oct 25

Where to stay in Santa Cruz?

A modern lobby with seating areas, a coffee table, and a large potted plant.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

A modern dining area with green chairs, a long table, and a wall with geometric patterns.

A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.

1. Ibis Santa Cruz DE LA Sierra

Equipetrol

$41

$41 total

Oct 31 - Nov 1

A poolside area with lounge chairs and a palm tree.

A dining table with breakfast items and a pool view.

A pathway through a lush garden with various trees and shrubs.

A banquet hall with long tables, chandeliers, and draped curtains.

2. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Equipetrol

$135

$135 total

Nov 7 - Nov 8

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A restaurant with a long counter, dark chairs, and hanging lights.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

An aerial view of a resort with a large swimming pool, multiple lounge areas, and surrounding greenery.

3. Camino Real Hotel

Santa Cruz

$174

$174 total

Oct 30 - Oct 31

A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

A modern lobby with a curved staircase, seating area, and a large wooden bookshelf.

A restaurant with a high ceiling, large windows, and a view of the cityscape. Tables are set with plates, glasses, and cutlery.

A luxurious banquet hall with ornate chandeliers, floral arrangements, and elegant table settings.

4. Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

$106

$106 total

Nov 1 - Nov 2

A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.

A buffet setup with various food items, including pastries, a cake, and beverages.

A hotel room with a large bed, a TV mounted on the wall, a dining area with chairs, and a sofa.

A modern staircase with glass railings, leading to a landing with a small garden area.

5. Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

$46

$46 total

Oct 18 - Oct 19

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A sauna with wooden walls and benches.

A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.

A spacious lobby with high ceilings, wooden beams, and a large seating area with wicker chairs.

6. Hotel Cortez

Equipetrol

$130

$130 total

Oct 23 - Oct 24

A modern restaurant with a city view, featuring glass tables, white chairs, and a large window with curtains.

A modern hotel lobby with a bar area, seating arrangements, and a television.

A hotel with a prominent 'Hampton' sign, large windows, and a modern facade.

A hotel room with a large bed, a desk, a chair, a telephone, and a view of the city through large windows.

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Santa Cruz

$74

$74 total

Oct 18 - Oct 19

A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

A rooftop pool area with a view of the city skyline at dusk.

A modern hotel room with a cityscape view at sunset, a tufted headboard, and a neatly made bed with white linens and dark accents.

A reception area with a marble counter, a large chandelier, and a digital display.

8. TRYP by Wyndham Santa Cruz

Equipetrol

$109

$109 total

Oct 17 - Oct 18

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

9. HOTEL OSHO

Santa Cruz

$51

$51 total

Oct 26 - Oct 27

A rooftop pool with a glass barrier reflecting the sunset and city skyline.

An outdoor dining area with tables and chairs, a wooden pergola with hanging lights, and a city view.

A buffet with various food items and a pitcher of orange juice.

A modern building with a stone facade and large windows. The name 'DEFINES COLLECTION' is prominently displayed on the building.

10. Delfines Collection Hotel By Mercure

Equipetrol

$48

$48 total

Oct 31 - Nov 1

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

11. Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$109

$109 total

Oct 26 - Oct 27

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

12. Novotel Santa Cruz De La Sierra

Santa Cruz

$119

$119 total

Nov 14 - Nov 15

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A hotel with a unique wavy facade, multiple parking spaces, and a clear blue sky.

A man in a suit entering an elevator.

A buffet setup with various food items and a serving area.

13. Hotel Las Américas

Centro Histórico

$21

$36 total

Oct 21 - Oct 22

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

Wicker furniture with cushions, potted plants, and a ceiling with lights.

A staircase with ornate lion statues at the base, a chandelier, and a framed artwork on the wall.

A traditional-style room with a sofa set, a table, and two chairs.

14. Lido Hotel

Centro Histórico

$25

$25 total

Oct 19 - Oct 20

A buffet setup with various food items and beverages.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

15. Hotel LP Equipetrol

Equipetrol

$45

$50 total

Nov 13 - Nov 14

A spacious room with a wooden floor and large windows offering a city view.

A hotel room with two beds, a nightstand, and a wall-mounted lamp.

A spacious lobby with a grand chandelier, marble flooring, and a statue.

A buffet table with various food items and a wine bottle.

16. Swissôtel Santa Cruz De La Sierra

Santa Cruz

$131

$131 total

Nov 5 - Nov 6

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A spacious lobby with a brick accent wall, a seating area with a coffee table, and a view of the kitchen in the background.

A room with a large window, a brick wall, and a hanging plant.

17. Chairú Eco Hotel

Santa Cruz

$47

$47 total

Nov 1 - Nov 2

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A table set for a meal with a view of a body of water and decorative lighting.

18. Sun Hotel

Santa Cruz

$97

$97 total

Oct 29 - Oct 30

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A building with a sign that reads "COSMOPOLITANO."

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

19. Cosmopolitano Hotel Boutique

Centro Histórico

$53

$53 total

Nov 16 - Nov 17

An outdoor dining area with tables and chairs, surrounded by plants and palm trees.

A hotel room with a bed, a sofa, a coffee table, and a vase of flowers.

A residential street with modern buildings, parked cars, and palm trees.

A kitchen with granite countertops, wooden chairs, a microwave, and a window.

20. Terranova Suites

Santa Cruz

$52

$52 total

Oct 17 - Oct 18

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The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A spacious lobby with a brick accent wall, a seating area with a coffee table, and a view of the kitchen in the background.

A room with a large window, a brick wall, and a hanging plant.

Chairú Eco Hotel

Santa Cruz

$51 off

$49

per night

$99 total

Reception

Room

Front of property

Room

Hotel Maywa

Santa Cruz

$10 off

$45

per night

$89 total

A modern lobby with seating areas, a coffee table, and a large potted plant.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

A modern dining area with green chairs, a long table, and a wall with geometric patterns.

A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$44 off

$64

per night

$127 total

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$29 off

$44

per night

$88 total

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$127 off

$157

per night

$313 total

A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

A group of women standing in a modern interior with wooden paneling and a reception desk.

A balcony with two wooden chairs and a table, overlooking a cityscape with various buildings.

A dining area with a glass table, metal chairs, and a buffet setup. There is a red sofa in the living area and a kitchen in the background.

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

$6 off

$27

per night

$54 total

A spacious lobby with a high ceiling, modern furniture, and a large chandelier.

A rooftop bar with a pool, lounge chairs, and a city view.

A modern interior with a white sofa, a dining area, and a staircase.

A spacious, well-lit interior with a modern white sofa set, a glass coffee table, and a dining area with red tablecloths.

Hotel Arenal

Centro Histórico

$21 off

$59

per night

$119 total

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A table set for a meal with a view of a body of water and decorative lighting.

Sun Hotel

Santa Cruz

$105

per night

$211 total

A buffet setup with various food items and beverages.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

Hotel LP Equipetrol

Equipetrol

$23 off

$64

per night

$133 total

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A sauna with wooden walls and benches.

A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.

A spacious lobby with high ceilings, wooden beams, and a large seating area with wicker chairs.

Hotel Cortez

Equipetrol

$32 off

$146

per night

$292 total

A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.

A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.

A hotel entrance with glass doors, a sign reading "LP HOTELES", and a green wall.

A modern restaurant interior with high tables and chairs, a large window with a view of the city, and a mural of a pink cherry blossom tree.

Hotel LP Santa Cruz Centro

Santa Cruz

$63 off

$57

per night

$119 total

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A restaurant with a long counter, dark chairs, and hanging lights.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

An aerial view of a resort with a large swimming pool, multiple lounge areas, and surrounding greenery.

Camino Real Hotel

Santa Cruz

$262

per night

$524 total

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A hotel with a unique wavy facade, multiple parking spaces, and a clear blue sky.

A man in a suit entering an elevator.

A buffet setup with various food items and a serving area.

Hotel Las Américas

Centro Histórico

$11 off

$48

per night

$95 total

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

Novotel Santa Cruz De La Sierra

Santa Cruz

$262

per night

$523 total

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern bathroom with a glass shower, a potted plant, and a towel rack.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

Hotel G

Santa Cruz

$11 off

$31

per night

$61 total

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A building with a sign that reads "COSMOPOLITANO."

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

Cosmopolitano Hotel Boutique

Centro Histórico

$60

per night

$60 total

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

An outdoor dining area with a brick wall, wooden shelves with plants, and a table set with plates of food and drinks.

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

$66 off

$109

per night

$109 total

A modern lobby with seating areas, a coffee table, and a large potted plant.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

A modern dining area with green chairs, a long table, and a wall with geometric patterns.

A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$45

per night

$45 total

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

A spacious lobby with a brick accent wall, a seating area with a coffee table, and a view of the kitchen in the background.

A room with a large window, a brick wall, and a hanging plant.

Chairú Eco Hotel

Santa Cruz

$28 off

$47

per night

$47 total

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A table set for a meal with a view of a body of water and decorative lighting.

Sun Hotel

Santa Cruz

$22 off

$108

per night

$108 total

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

Wicker furniture with cushions, potted plants, and a ceiling with lights.

A staircase with ornate lion statues at the base, a chandelier, and a framed artwork on the wall.

A traditional-style room with a sofa set, a table, and two chairs.

Lido Hotel

Centro Histórico

$3 off

$25

per night

$25 total

Reception

Room

Front of property

Room

Hotel Maywa

Santa Cruz

$5 off

$45

per night

$45 total

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$12 off

$51

per night

$51 total

A spacious lobby with large windows, modern chandeliers, and a seating area with sofas and chairs.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A hotel room with two beds, a nightstand, a lamp, and a view of the city.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

Novotel Santa Cruz De La Sierra

Santa Cruz

$119

per night

$119 total

A spacious lobby with a high ceiling, modern furniture, and a large chandelier.

A rooftop bar with a pool, lounge chairs, and a city view.

A modern interior with a white sofa, a dining area, and a staircase.

A spacious, well-lit interior with a modern white sofa set, a glass coffee table, and a dining area with red tablecloths.

Hotel Arenal

Centro Histórico

$10 off

$59

per night

$59 total

A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

A group of women standing in a modern interior with wooden paneling and a reception desk.

A balcony with two wooden chairs and a table, overlooking a cityscape with various buildings.

A dining area with a glass table, metal chairs, and a buffet setup. There is a red sofa in the living area and a kitchen in the background.

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

$3 off

$27

per night

$27 total

A buffet setup with various food items and beverages.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

Hotel LP Equipetrol

Equipetrol

$24 off

$45

per night

$50 total

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A restaurant with a long counter, dark chairs, and hanging lights.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

An aerial view of a resort with a large swimming pool, multiple lounge areas, and surrounding greenery.

Camino Real Hotel

Santa Cruz

$189

per night

$189 total

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern bathroom with a glass shower, a potted plant, and a towel rack.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

Hotel G

Santa Cruz

$12 off

$27

per night

$27 total

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A hotel with a unique wavy facade, multiple parking spaces, and a clear blue sky.

A man in a suit entering an elevator.

A buffet setup with various food items and a serving area.

Hotel Las Américas

Centro Histórico

$3 off

$26

per night

$26 total

You may also like pet-friendly hotels in Santa Cruz

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A building with a sign that reads "COSMOPOLITANO."

A rooftop pool area with a glass balustrade, wooden deck, and a seating area with cushions and a small table.

Cosmopolitano Hotel Boutique

Centro Histórico

$53

$53 total

Nov 16 - Nov 17

A modern lobby with seating areas, a coffee table, and a large potted plant.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

A modern dining area with green chairs, a long table, and a wall with geometric patterns.

A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$41

$41 total

Oct 31 - Nov 1

A hotel room with a round wooden table, two single beds, a red chair, and a wooden wall.

A spacious living area with a black sofa, a glass coffee table, and a plant.

A compact kitchenette with a refrigerator, a coffee maker, and a small table with a laptop.

A hotel room with a bed, a desk with a computer and two remote controls, a window with a city view, and a wooden headboard.

Hotel Pascana centro

Centro Histórico

$72

$72 total

Oct 19 - Oct 20

A hotel room with a bed, a desk with a chair, a television, and a window with a city view.

A lobby with a marble floor, an elevator, and a view of the outdoor seating area.

A corridor with tiled flooring, potted plants, and a view of a building with a thatched roof.

An aerial view of a residential area with a swimming pool, a playground, and a large building with a red roof.

Gran Hotel Santa Cruz

Centro Histórico

$58

$58 total

Oct 17 - Oct 18

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$51

$51 total

Oct 26 - Oct 27

A modern rooftop pool with a city view, wooden flooring, and a seating area.

A modern office space with a dark wood desk, a black office chair, a flat-screen TV mounted on the wall, and an air conditioning unit.

A modern living room with a sofa and a kitchen area featuring a microwave, kettle, and a coffee machine.

A modern hotel room with a bed, bedside table, and a desk with a chair.

AMERICA APARTMENTS

Santa Cruz

$34

$34 total

Oct 19 - Oct 20

A buffet setup with various food items and beverages.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a wall with various artworks.

Hotel LP Equipetrol

Equipetrol

$45

$50 total

Nov 13 - Nov 14

A modern bedroom with a bed, bedside table, and a desk with a laptop.

A modern bathroom with a glass shower, a potted plant, and a towel rack.

A modern bathroom with a glass shower enclosure, a potted plant, a towel rack, and a black countertop.

Hotel G

Santa Cruz

$27

$27 total

Nov 14 - Nov 15

A hotel room with two beds, a desk, a chair, a television, and a window with curtains.

A wooden door with a notice and a small bedside table with a lamp.

A reception desk with a wooden finish, a framed wildlife painting, and a green leaf-patterned wall mural.

A café area with a staircase, a sofa, and tables with chairs.

Gran Hotel Mediterráneo

Centro Histórico

$55

$55 total

Oct 17 - Oct 18

A modern hotel room with a bed, a nightstand, a lamp, a painting, a kitchen area, and a bathroom.

A modern kitchen with wooden cabinets, a black countertop, and a built-in stove.

A cozy seating area with a round wooden table, a white cup, and a book.

A compact kitchen with a stove, sink, and coffee maker. A bed with a blue pillow is visible in the background.

Equipetrol Suites Apart Hotel

Santa Cruz

$51

$51 total

Oct 17 - Oct 18

View all properties

You can also stay at family-friendly hotels in Santa Cruz

A hotel room with a large bed, bedside tables, a desk with a chair, a small refrigerator, and a TV mounted on the wall.

A paved outdoor area with a row of chairs, a planter with large-leafed plants, and a staircase leading to a higher level.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

HOTEL OSHO

Santa Cruz

$51

$51 total

Oct 26 - Oct 27

A poolside area with lounge chairs and a palm tree.

A dining table with breakfast items and a pool view.

A pathway through a lush garden with various trees and shrubs.

A banquet hall with long tables, chandeliers, and draped curtains.

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Equipetrol

$135

$135 total

Nov 7 - Nov 8

A modern lobby with seating areas, a coffee table, and a large potted plant.

A hotel interior with a modern design, featuring a large window with a view of palm trees and a sign that reads "ibis HOTEL". There are three green chairs and a small round table.

A modern dining area with green chairs, a long table, and a wall with geometric patterns.

A hotel room with two beds, a desk, a chair, a TV, a window with curtains, and artwork on the wall.

Ibis Santa Cruz DE LA Sierra

Equipetrol

$41

$41 total

Oct 31 - Nov 1

A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.

A buffet setup with various food items, including pastries, a cake, and beverages.

A hotel room with a large bed, a TV mounted on the wall, a dining area with chairs, and a sofa.

A modern staircase with glass railings, leading to a landing with a small garden area.

Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

$46

$46 total

Oct 18 - Oct 19

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A restaurant with a long counter, dark chairs, and hanging lights.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

An aerial view of a resort with a large swimming pool, multiple lounge areas, and surrounding greenery.

Camino Real Hotel

Santa Cruz

$174

$174 total

Oct 30 - Oct 31

A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

A rooftop pool area with a view of the city skyline at dusk.

A modern hotel room with a cityscape view at sunset, a tufted headboard, and a neatly made bed with white linens and dark accents.

A reception area with a marble counter, a large chandelier, and a digital display.

TRYP by Wyndham Santa Cruz

Equipetrol

$109

$109 total

Oct 17 - Oct 18

A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

A modern lobby with a curved staircase, seating area, and a large wooden bookshelf.

A restaurant with a high ceiling, large windows, and a view of the cityscape. Tables are set with plates, glasses, and cutlery.

A luxurious banquet hall with ornate chandeliers, floral arrangements, and elegant table settings.

Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

$106

$106 total

Nov 1 - Nov 2

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A sauna with wooden walls and benches.

A high-rise hotel with multiple floors, a swimming pool, and a well-lit street with cars.

A spacious lobby with high ceilings, wooden beams, and a large seating area with wicker chairs.

Hotel Cortez

Equipetrol

$130

$130 total

Oct 23 - Oct 24

A hotel room with a bed, a desk with a chair, a television, and a window with a city view.

A lobby with a marble floor, an elevator, and a view of the outdoor seating area.

A corridor with tiled flooring, potted plants, and a view of a building with a thatched roof.

An aerial view of a residential area with a swimming pool, a playground, and a large building with a red roof.

Gran Hotel Santa Cruz

Centro Histórico

$58

$58 total

Oct 17 - Oct 18

A modern restaurant with a city view, featuring glass tables, white chairs, and a large window with curtains.

A modern hotel lobby with a bar area, seating arrangements, and a television.

A hotel with a prominent 'Hampton' sign, large windows, and a modern facade.

A hotel room with a large bed, a desk, a chair, a telephone, and a view of the city through large windows.

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Santa Cruz

$74

$74 total

Oct 18 - Oct 19

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Go beyond your typical stay in Santa Cruz

Pool

Family friendly

Hot tub

Spa

Pet friendly

Our prices for hotels in Santa Cruz are cheapest in February

Top neighborhoods in Santa Cruz

Equipetrol

Santa Cruz's Equipetrol neighborhood offers attractions including Santa Cruz Zoo.

Centro Histórico

Santa Cruz's Centro Histórico neighborhood is home to attractions such as Plaza 24 de Septiembre and La Recova Artisan Walk.

Hamacas

Zona Sur (South Zone)

Urubó

Top landmarks in Santa Cruz

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)

If you're planning a bit of sightseeing head to Plaza 24 de Septiembre— just one of the monuments in Centro Histórico.

A historic tower with a clock, surrounded by lush greenery and palm trees.

San Lorenzo Cathedral

9.0/10 (84 reviews)

Centro Histórico is home to San Lorenzo Cathedral, so why not stop by during your stay in Santa Cruz.

Ventura Mall

9.0/10 (183 reviews)

If you like shopping, take time out to go to Ventura Mall when in Santa Cruz.

Guembe Biocenter

8.8/10 (60 reviews)

Ready for an education in local botany? Guembe Biocenter should make your list of places to visit, located 1.2 mi (2 km) from central Colinas del Urubo. Want to stretch your legs some more? Head to Arenal Park, located nearby.

Santa Cruz Zoo

8.4/10 (53 reviews)

It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a trip to Santa Cruz Zoo, located 1.7 mi (2.8 km) from central Santa Cruz. If you have fun at Santa Cruz Zoo, you'll love Guembe Biocenter and Franco Aleman Cultural Center, both located nearby.

Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)

You can catch an event at Ramon Tahuichi Aguilera Stadium, located 0.8 mi (1.3 km) from central Santa Cruz.

Blacutt Square

8.2/10 (19 reviews)

You might want to get your camera out and head to Blacutt Square— just one of the landmarks located 0.7 mi (1.1 km) from central Santa Cruz.

Cine Center

8.0/10 (53 reviews)

Cine Center is 1 mi (1.6 km) from central Santa Cruz, why not stop by during your stay. If you enjoy the show and want to see another, Casa Municipal de Cultura Raúl Otero Reiche isn't far.

Learn more about Santa Cruz

Santa Cruz is applauded for its cultural attractions such as Ethno-folkloric Museum and Cine Center.

See all hotels in Santa Cruz

A historic cathedral with two prominent towers, surrounded by urban buildings and palm trees.

Check out reviews of Santa Cruz hotels guests love

Hotel Cortez

Hotel Cortez

10/10 Excellent

"El hotel es fantastico, el desayuno excelente, los servicios que brinda el hotel son un plus para el huésped. En general, el personal es atento y amable. Sin embargo, tuvimos problemas en el check in, la señorita que nos recibió indicó que no teníamos reservación. Se le indicó que la reservación se había hecho por Expedia y ella insistió en que no teníamos alguna. Cuando llamé a Expedia, nos dijo que, aunque el hotel estaba lleno, nos darían una habitación. Esta señorita parece no ser tan amable, lo cual es la excepción, pues el personal es atento y presto a ayudar al huésped."

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

10/10 Excellent

"Muy buen servicio"

Chairú Eco Hotel

Chairú Eco Hotel

8/10 Good

"The breakfast was not that good, but everything was good"

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

10/10 Excellent

"The room was very clean and the breakfast was fantastic. Overall it was a great experience."

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

10/10 Excellent

"All around good price and location"

Delfines Collection Hotel By Mercure

Delfines Collection Hotel By Mercure

10/10 Excellent

"Todo muy bien"

Hotel LP Equipetrol

Hotel LP Equipetrol

8/10 Good

"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"

Frequently asked questions

What hotels do travelers recommend in Santa Cruz?

Guests like Ibis Santa Cruz DE LA Sierra, Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Marriott Santa Cruz de la Sierra Hotel.

Where can I find free parking at my hotel in Santa Cruz?

These hotels offer the perk of free parking: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Hotel LP Equipetrol and Hotel LP Santa Cruz Centro. There are 8 options you may want to check out on our site.

Can I book refundable hotels in Santa Cruz?

If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

Where should I consider staying in Santa Cruz if I'm looking for a reasonably priced accommodation?

An inexpensive option worth considering is Hotel LP Equipetrol. You can browse all 7 choices on our site.

Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?

If you want to find a good alternative to a hotel, browse our selection of 23 vacation homes. In addition, you can choose from 198 apartments.

What will the weather in Santa Cruz be like during my trip?

Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.

Why should I book my Santa Cruz accommodation with Hotels.com?

There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.