Hotels in Santa Cruz
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Aug 24 - Aug 25Tomorrow
Aug 25 - Aug 26This weekend
Aug 28 - Aug 30Next weekend
Sep 4 - Sep 6Where to stay in Santa Cruz?
Ibis Santa Cruz DE LA Sierra
Ibis Santa Cruz DE LA SierraSanta Cruz
$36
$36 total
Sep 8 - Sep 9
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelSanta Cruz
$135
$135 total
Aug 30 - Aug 31
Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra HotelSanta Cruz
$106
$106 total
Sep 4 - Sep 5
Premium Suites Deluxe Aparthotel Equipetrol
Premium Suites Deluxe Aparthotel EquipetrolSanta Cruz
$46
$46 total
Aug 30 - Aug 31
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol, BoliviaSanta Cruz
$74
$74 total
Aug 27 - Aug 28
Delfines Collection Hotel By Mercure
Delfines Collection Hotel By MercureSanta Cruz
$48
$48 total
Sep 8 - Sep 9
TRYP by Wyndham Santa Cruz
TRYP by Wyndham Santa CruzSanta Cruz
$98
$98 total
Aug 26 - Aug 27
Novotel Santa Cruz De La Sierra
Novotel Santa Cruz De La SierraSanta Cruz
$129
$129 total
Sep 1 - Sep 2
Alfonsina Hotel Boutique by Inboccaluppo
Alfonsina Hotel Boutique by InboccaluppoSanta Cruz
$108
$108 total
Aug 25 - Aug 26
Swissôtel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La SierraSanta Cruz
$164
$164 total
Sep 8 - Sep 9
Cosmopolitano Hotel Boutique
Cosmopolitano Hotel BoutiqueSanta Cruz
$55
$55 total
Sep 2 - Sep 3
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$41
per night
$81 total
Sign in for extra savings
$38 off
Hotel LP Santa Cruz Centro$40
per night
$85 total
$17 off
Cosmopolitano Hotel Boutique$76
per night
$152 total
$33 off
TRYP by Wyndham Santa Cruz$93
per night
$185 total
$134 off
Alfonsina Hotel Boutique by Inboccaluppo$108
per night
$216 total
$130
per night
$259 total
Sign in for extra savings
$6 off
Apart Hotel Premium Suites Santa Cruz$27
per night
$54 total
$158
per night
$315 total
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$39
per night
$79 total
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$38 off
Hotel LP Santa Cruz Centro$40
per night
$85 total
$137
per night
$275 total
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$30 off
Alfonsina Hotel Boutique by Inboccaluppo$134
per night
$268 total
$6 off
Apart Hotel Premium Suites Santa Cruz$27
per night
$54 total
$33 off
TRYP by Wyndham Santa Cruz$93
per night
$185 total
$36 off
Hotel BY Armonia SCZ$77
per night
$153 total
$49
per night
$49 total
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$19 off
Cosmopolitano Hotel Boutique$77
per night
$77 total
$11 off
TRYP by Wyndham Santa Cruz$98
per night
$98 total
$15 off
Alfonsina Hotel Boutique by Inboccaluppo$134
per night
$134 total
$18 off
Hotel LP Santa Cruz Centro$41
per night
$46 total
$3 off
Apart Hotel Premium Suites Santa Cruz$27
per night
$27 total
$203
per night
$203 total
Sign in for extra savings
Check out pet-friendly hotels in Santa Cruz
$36
$36 total
Sep 8 - Sep 9
$41
$46 total
Sep 11 - Sep 12
$55
$55 total
Sep 2 - Sep 3
$50
$50 total
Aug 25 - Aug 26
You can also stay at hotels with a pool in Santa Cruz
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio HotelSanta Cruz
$135
$135 total
Aug 30 - Aug 31
$46
$46 total
Aug 30 - Aug 31
$106
$106 total
Sep 4 - Sep 5
$48
$48 total
Sep 8 - Sep 9
$55
$55 total
Sep 2 - Sep 3
$129
$129 total
Sep 1 - Sep 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all propertiesGo beyond your typical stay in Santa Cruz
Pet friendly
Family friendly
Our prices for hotels in Santa Cruz are cheapest in February
Our prices for hotels in Santa Cruz are cheapest in February
Price trends for hotels in Santa Cruz
Pricing is based on two traveler single night rates
Top neighborhoods in Santa Cruz
Top landmarks in Santa Cruz
Plaza 24 de Septiembre
8.8/10 (164 reviews)
If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre— just one of the monuments in central Santa Cruz.
San Lorenzo Cathedral
9.0/10 (84 reviews)
San Lorenzo Cathedral is in the heart of Santa Cruz, so why not stop by during your stay.
Ventura Mall
9.0/10 (183 reviews)
If you like shopping, take time out to go to Ventura Mall when in Santa Cruz.
Guembe Biocenter
8.8/10 (60 reviews)
Ready for an education in local botany? Guembe Biocenter should make your list of places to visit, located 1.2 mi (2 km) from central Colinas del Urubo. Want to stretch your legs some more? Head to Arenal Park, located nearby.
Santa Cruz Zoo
8.4/10 (53 reviews)
It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a trip to Santa Cruz Zoo, located 1.7 mi (2.8 km) from central Santa Cruz. If you have fun at Santa Cruz Zoo, you'll love Guembe Biocenter and Artecampo, both located nearby.
Cine Center
8.0/10 (53 reviews)
Cine Center is 1 mi (1.6 km) from central Santa Cruz, why not stop by during your stay. If you enjoy the show and want to see another, Casa Municipal de Cultura Raúl Otero Reiche isn't far.
Ramon Tahuichi Aguilera Stadium
8.4/10 (18 reviews)
You can catch an event at Ramon Tahuichi Aguilera Stadium, located 0.8 mi (1.3 km) from central Santa Cruz.
Lomas de Arena Regional Park
8.4/10 (28 reviews)
Commune with nature and explore Lomas de Arena Regional Park located 10.7 mi (17.1 km) from central Santa Cruz.
Learn more about Santa Cruz
Santa Cruz is applauded for its cultural attractions such as Cine Center and Ethno-folkloric Museum.
See all hotels in Santa Cruz
Check out reviews of Santa Cruz hotels guests love
Sun Hotel
10/10 Excellent
"ten confianza llegando a este hotel, el servicio es espectacular"
Marriott Santa Cruz de la Sierra Hotel
10/10 Excellent
"Staff was super as well as how clean the room was."
Hotel Cortez
10/10 Excellent
"Great place. Safe, clean, attractive everything u could want"
Ibis Santa Cruz DE LA Sierra
10/10 Excellent
"Buen hotel Limpio y comodo"
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
10/10 Excellent
"Great breakfast and beautiful property. Would come here again. Felt safe and comfortable."
Delfines Collection Hotel By Mercure
10/10 Excellent
"Todo muy bien"
Hotel LP Equipetrol
8/10 Good
"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"
Alfonsina Hotel Boutique by Inboccaluppo
10/10 Excellent
"Good hotel. Very contemporary; buffet breakfast included. We walked to the old part of the city/cathedral - probably about 40 minutes walk but can stop for a coffee along the way! Restaurant and bar in hotel. Hotel also close to many other restaurants/bars"
Apart Hotel Premium Suites Santa Cruz
10/10 Excellent
"Great location."