Hotels in Santa Cruz

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Jan 16 - Jan 17
Tomorrow
Jan 17 - Jan 18
This weekend
Jan 16 - Jan 18
Next weekend
Jan 23 - Jan 25

Where to stay in Santa Cruz?

Living area
Posada Express Fast Check
Posada Express Fast Check
3.0 star property
Santa Cruz
7.4 out of 10, Good, (3 reviews)
  • cleanliness
    Modern inn in Santa Cruz offers a comfortable stay, just minutes from Play Land.
The price is $29
$32 total
Jan 19 - Jan 20
Posada Express Fast Check
Outdoor pool
Mirador del Cielo
Mirador del Cielo
3.0 star property
Santa Cruz
4.0 out of 10, (1 review)
The price is $23
$23 total
Jan 21 - Jan 22
Mirador del Cielo
Standard Suite, 1 Queen Bed | Hypo-allergenic bedding, down comforters, desk, laptop workspace
Equipetrol Suites Apart Hotel
Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.8 out of 10, Excellent, (9 reviews)
  • cleanliness
    Enjoy a central stay with kitchenette-equipped suites near Cine Center.
The price is $34
$34 total
Jan 17 - Jan 18
Equipetrol Suites Apart Hotel
Exterior
Surbackpackers
Surbackpackers
3.0 star property
Santa Cruz
The price is $25
$25 total
Jan 20 - Jan 21
Surbackpackers
1 bedroom, in-room safe, desk, iron/ironing board
Apart Hotel Premium Suites Santa Cruz
Apart Hotel Premium Suites Santa Cruz
3.5 star property
Santa Cruz
8.6 out of 10, Excellent, (98 reviews)
  • cleanliness
    Convenient downtown apartment with kitchen and furnished balcony in Santa Cruz.
Apart Hotel Premium Suites Santa Cruz
Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers
Premium Suites Deluxe Aparthotel Equipetrol
Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (82 reviews)
The price is $39
$39 total
Jan 18 - Jan 19
Premium Suites Deluxe Aparthotel Equipetrol
Reception
Lido Hotel
Lido Hotel
3.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (31 reviews)
  • cleanliness
    Enjoy free perks and easy access to cultural attractions in downtown Santa Cruz.
The price is $37
$37 total
Jan 17 - Jan 18
Lido Hotel
Outdoor pool
Delfines Collection Hotel By Mercure
Delfines Collection Hotel By Mercure
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (74 reviews)
  • cleanliness
    Contemporary hotel near popular Santa Cruz attractions offers comfort and convenience.
The price is $42
$42 total
Jan 23 - Jan 24
Delfines Collection Hotel By Mercure
BBQ/picnic area
Casa Por Temporadas
Casa Por Temporadas
2.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1 review)
  • cleanliness
    Tranquil guesthouse in Santa Cruz with outdoor pool and private patios to unwind.
The price is $86
$86 total
Jan 17 - Jan 18
Casa Por Temporadas
Miscellaneous
Ibis Santa Cruz DE LA Sierra
Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (82 reviews)
  • cleanliness
    Welcoming hotel in Santa Cruz offers urban comfort with convenient access to city sights.
The price is $43
$43 total
Jan 17 - Jan 18
Ibis Santa Cruz DE LA Sierra
Lobby sitting area
Hotel Arenal
Hotel Arenal
3.5 star property
Santa Cruz
7.6 out of 10, Good, (60 reviews)
  • cleanliness
    Lush pool oasis in Santa Cruz with massage services and fitness amenities nearby.
The price is $59
$59 total
Jan 17 - Jan 18
Hotel Arenal
Outdoor pool
AMERICA APARTMENTS
AMERICA APARTMENTS
3.0 star property
Santa Cruz
  • cleanliness
    Cozy Santa Cruz apartments with outdoor pool and private patios.
The price is $55
$55 total
Jan 17 - Jan 18
AMERICA APARTMENTS
Dining room
Hotel BY Armonia SCZ
Hotel BY Armonia SCZ
3.0 star property
Santa Cruz
8.4 out of 10, Very Good, (7 reviews)
  • cleanliness
    Colonial-style hotel with outdoor pool, sauna, and complimentary perks in Santa Cruz.
Hotel BY Armonia SCZ
Reception
Urban Suites
Urban Suites
3.0 star property
Santa Cruz
  • cleanliness
    Tranquil urban escape with a refreshing pool in the heart of Santa Cruz.
The price is $55
$55 total
Jan 17 - Jan 18
Urban Suites
Standard Room, 2 Twin Beds | Premium bedding, minibar, in-room safe, desk
Hotel LP Santa Cruz Centro
Hotel LP Santa Cruz Centro
3.0 star property
Santa Cruz
8.0 out of 10, Very Good, (282 reviews)
  • cleanliness
    Unwind in Santa Cruz's entertainment district with easy access to city attractions.
The price is $49
$49 total
Feb 3 - Feb 4
Hotel LP Santa Cruz Centro
Exterior detail
TRYP by Wyndham Santa Cruz
TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (149 reviews)
  • cleanliness
    Energizing hotel in the entertainment district, close to Santa Cruz's top attractions.
The price is $99
$99 total
Jan 17 - Jan 18
TRYP by Wyndham Santa Cruz
Triple Room | Free WiFi
Hotel Las Américas
Hotel Las Américas
3.0 star property
Santa Cruz
6.0 out of 10, (1 review)
  • cleanliness
    Convenient hotel with free breakfast and WiFi near cultural attractions in Santa Cruz.
The price is $35
$35 total
Jan 17 - Jan 18
Hotel Las Américas
Premium Room, 1 Queen Bed, Bathtub | Minibar, in-room safe, individually decorated, individually furnished
Cosmopolitano Hotel Boutique
Cosmopolitano Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (122 reviews)
  • cleanliness
    Poolside relaxation and cultural attractions await at this boutique Santa Cruz hotel.
Cosmopolitano Hotel Boutique
Lounge
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (259 reviews)
  • cleanliness
    Escape to Santa Cruz's vibrant Equipetrol district with luxury amenities and rooftop dining.
The price is $74
$74 total
Feb 1 - Feb 2
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Outdoor pool
Sun Hotel
Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (333 reviews)
  • cleanliness
    Santa Cruz hotel with airport shuttle, pool, and spa treatments awaits your stay.
The price is $90
$90 total
Jan 18 - Jan 19
Sun Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Get last-minute hotel deals in Santa Cruz and save more

Sign in to unlock great savings.
Showing deals for:Jan 23 - Jan 25
VIP Access
Lobby sitting area
Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (104 reviews)
The price is $170
per night
$340 total
MOD
Sign in for extra savings
Novotel Santa Cruz De La Sierra
Showing deals for:Feb 15 - Feb 16
VIP Access
Outdoor pool
Sun Hotel

Sun Hotel

Sun Hotel
3.5 star property
Santa Cruz
8.2 out of 10, Very Good, (333 reviews)
$12 off
The price is $108
per night
$108 total
Sun Hotel

Check out hotels with a pool in Santa Cruz

Lobby sitting area
Hotel Arenal

Hotel Arenal

Hotel Arenal
3.5 star property
Santa Cruz
7.6 out of 10, Good, (60)
The price is $59
$59 total
Jan 17 - Jan 18
Hotel Arenal
View all properties

You may also like hotels with spas in Santa Cruz

Outdoor pool
Mirador del Cielo

Mirador del Cielo

Mirador del Cielo
3.0 star property
Santa Cruz
4.0 out of 10, (1)
The price is $23
$23 total
Jan 21 - Jan 22
Mirador del Cielo
View all properties

You can also stay at family-friendly hotels in Santa Cruz

Lobby sitting area
Hotel Arenal

Hotel Arenal

Hotel Arenal
3.5 star property
Santa Cruz
7.6 out of 10, Good, (60)
The price is $59
$59 total
Jan 17 - Jan 18
Hotel Arenal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

When is the best time to visit Santa Cruz?

Our prices for hotels in Santa Cruz are cheapest in February
Price trends for hotels in Santa Cruz
Pricing is based on two traveler single night rates
View properties in January
Currently viewing crowd sizes and weather for January.
Typical weather for Santa Cruz
January
High 31°C / low 22°C. Sunny most days.
View properties in January
31°
weather_sun
January, no crowd data, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
29°
weather_cloudy
February, no crowd data, average high temperature 29 degrees Celsius, average low temperature 22 degrees Celsius. Cloudy most days.
22°
29°
weather_sun
March, no crowd data, average high temperature 29 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
28°
weather_sun
April, no crowd data, average high temperature 28 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
25°
weather_sun
May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
18°
24°
weather_sun
June, no crowd data, average high temperature 24 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
25°
weather_sun
July, no crowd data, average high temperature 25 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
28°
weather_sun
August, no crowd data, average high temperature 28 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
18°
31°
weather_sun
September, no crowd data, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
32°
weather_sun
October, no crowd data, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
32°
weather_sun
November, no crowd data, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
31°
weather_sun
December, no crowd data, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
Monthly weather averages (˚C)

Top neighborhoods in Santa Cruz

Top landmarks in Santa Cruz

Plaza 24 de Septiembre showing street scenes

Plaza 24 de Septiembre

4.4/5 (70 reviews)
If you're planning a bit of sightseeing during your trip, head to Plaza 24 de Septiembre— just one of the monuments in central Santa Cruz.
See properties
San Lorenzo Cathedral showing a church or cathedral and interior views

San Lorenzo Cathedral

4.5/5 (36 reviews)
San Lorenzo Cathedral is in the heart of Santa Cruz, so why not stop by during your stay.
See properties

Learn more about Santa Cruz

Santa Cruz is applauded for its cultural attractions such as Cine Center and Sacred Art Museum.

See all hotels in Santa Cruz
San Lorenzo Cathedral showing a garden

Check out reviews of Santa Cruz hotels guests love

Lido Hotel

Lido Hotel

10/10 Excellent
"We stayed at the fabulous Lido Hotel for 2 nights in December 2025. The hotel is located in central Santa Cruz, within a 4 block walk from Plaza 24 de Septiembre, and also a short 10 minute walk from the iconic Cristo Redentor statue. Check in was quick and painless, and the front desk staff was friendly and helpful. The room itself was spacious, clean and comfortable, with a large attached full bathroom. The air conditioner did a great job of cooling the room. Breakfast was served each morning in the attached Chinese restaurant, and featured eggs, breakfast meats, fruits, juices, cereal and yogurt, and was a great way to fuel up before venturing out to explore Santa Cruz. Without equivocation, I highly recommend the Lido Hotel to anyone in search of a clean comfortable hotel at an affordable price in the enchanting metrolopolis of Santa Cruz de la Sierra, Bolivia. Dr. Kingstone Shih and Laura Meneses Los Altos, California USA "
kingstone 2-night trip
Posted 9 days ago
Lido Hotel

Frequently asked questions

What hotels do travelers recommend in Santa Cruz?
Ibis Santa Cruz DE LA Sierra, Chairú Eco Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are all accommodations that are popular with guests.
Where can I find free parking at my hotel in Santa Cruz?
These hotels offer the perk of free parking: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Hotel LP Equipetrol and Swissôtel Santa Cruz De La Sierra. There are 8 options you may want to check out on our site.
Can I book refundable hotels in Santa Cruz?
If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 23 vacation homes. In addition, you can choose from 182 apartments.
What will the weather in Santa Cruz be like during my trip?
Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.
Why should I book my Santa Cruz accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.