Hotels in San Isidro

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Where to stay in San Isidro?

A waterfront property with a dock, a boat, and a building with a balcony.

A bedroom with a bed, a ceiling fan, a nightstand, and a bathroom visible through an open door.

A waterfront restaurant with outdoor seating, a dock, and a boat.

A bar area with a bartender, a computer monitor, and various bar tools.

1. Mamacita's Guest House

Culebra Pueblo

$140

$168 total

includes taxes & fees

Oct 2 - Oct 3

A covered outdoor dining area with wooden tables and chairs, overlooking a marina with sailboats.

A view from a window overlooking a building with a balcony, a palm tree, and a body of water.

A bedroom with a bed, a nightstand, a lamp, a window with a view of the sea, and a door leading to an outdoor balcony.

A two-story building with a sign reading "El Navegante" and a staircase leading to the upper floor.

2. El Navegante de Culebra

Culebra Pueblo

$170

$217 total

includes taxes & fees

Oct 12 - Oct 13

A bedroom with a large bed, a ceiling fan, and a balcony with a view of the sea.

A bathroom with a large window offering a view of a lake and a distant island.

A bathroom with two sinks, a large mirror, and a window with a scenic view of a sunset over water.

A pool area with a view of the ocean at sunset, surrounded by palm trees and a deck with seating.

3. Las Quintas Reserve

Culebra

$270

$374 total

includes taxes & fees

Oct 22 - Oct 23

A beach with clear turquoise water, sandy shore, and palm trees.

A balcony with two chairs and a table, overlooking a coastal view with buildings and a clear sky.

A gated entrance with palm trees, a dirt path, and a view of the sea at sunset.

A multi-story building with a pool, surrounded by lush greenery and palm trees.

4. Sea Gate Hotel

Isabel II

$110

$126 total

includes taxes & fees

Oct 1 - Oct 2

A room with a sofa, two chairs, a coffee table, and a large abstract painting on the wall.

A garden with several outdoor seating areas and a variety of tropical plants.

A spacious dining area with wooden tables and chairs, a ceiling fan, and a painting of a beach scene on the wall.

A hotel room with two beds, a green geometric wall design, a ceiling light, and a TV on the right.

5. Vieques Tropical Guest House

Isabel II

$51

$113 total

includes taxes & fees

Oct 1 - Oct 2

A clear blue pool with lounge chairs and palm trees.

A building with a covered entrance, palm trees, and beach chairs.

A person seated at a table with a plate of food, a glass of wine, and a bottle of Cuvée wine. The table is on an outdoor balcony with a view of a body of water and mountains in the background.

A coastal view with a body of water, distant hills, and buildings with red-tiled roofs.

6. Costa Bonita Private Villa 604

Culebra

$154

$335 total

includes taxes & fees

Oct 6 - Oct 7

A deck with lounge chairs and colorful umbrellas overlooking a scenic view.

A modern bedroom with a large bed, a ceiling fan, a painting on the wall, and a view through the glass door.

A spacious room with a high ceiling, a bar area, and a large window offering a view of lush greenery.

A modern bathroom with a large mirror, dark wooden cabinets, a sink, and a towel rack.

7. Old Crow Hotel and Suites

Vieques

$125

$143 total

includes taxes & fees

Oct 1 - Oct 2

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Go beyond your typical stay in San Isidro

Pool

Top landmarks in San Isidro

Playa Tortola

When the beach is calling your name, you might want to head down to Playa Tortola, located 0.8 mi (1.2 km) from central San Isidro. If you want to continue walking by the waves, head to Playa Cayo Norte located nearby.

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Playa Cayo Norte

Whether you want to collect beach glass or watch the sunset, Playa Cayo Norte is a spot you might want to check out, located 1.4 mi (2.3 km) from central San Isidro. If you want to continue walking by the waves, head to Playa Tortola located nearby.

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Check out reviews of San Isidro hotels guests love

Sea Gate Hotel

10/10 Excellent

"The hotel have a very nice view and it’s super clean, and I loved the owner she was very sweet and helpful 👌"

Club Seabourne Boutique Hotel

10/10 Excellent

"A wonderful stay at this hotel. It's close to the bay and very quiet at night. The garden is beautiful and very well maintained. The staff were all very warm and welcoming, treating us like family. Overall, I think it's a truly excellent hotel for this area. If I have the chance to come back, I will definitely want to stay at this hotel again."

Mamacita's Guest House

10/10 Excellent

"Super place to stay for a few days are a week"

Las Quintas Reserve

10/10 Excellent

"This property is amazing, great view, nice staff that are very responsive and includes breakfast every day!"

Vieques BioBay Bed and Breakfast

10/10 Excellent

"⭐️⭐️⭐️⭐️⭐️"

Costa Bonita Private Villa 602

10/10 Excellent

"Amazing view! Really neat apartment."

Frequently asked questions

What hotels do travelers like in San Isidro?

Guests like Mamacita's Guest House, Club Seabourne Boutique Hotel and Las Quintas Reserve.

Can I book a refundable accommodation in San Isidro?

If you're looking for the flexibility to change your plans to San Isidro, most properties offer refundable* rates you can book. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in San Isidro be like during my visit?

San Isidro is a great place to visit any time of year with an average temperature of 78°F during the coldest months.

Why should I book my San Isidro hotel through Hotels.com?

There are plenty of reasons to book your San Isidro travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.