Hotels in Santa María Centro

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Oct 23 - Oct 24
Tomorrow
Oct 24 - Oct 25
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Where to stay in Santa María Centro?

A modern room with a white sofa, a small table with a potted plant, and a view of the city through large windows.
A hotel room with three beds, each with white bedding and black and white patterned throw pillows. There are bedside lamps and a large mirror on the wall.
A modern hotel lobby with a reception desk, a red chair, and a chandelier.
A swimming pool with two drinks on a white tray.

1. Amerian Rafaela Hotel

Amerian Rafaela Hotel
Rafaela
$103
$103 total
Oct 24 - Oct 25
Amerian Rafaela Hotel
View all properties

Check out reviews of Santa María Centro hotels guests love

Frequently asked questions

Can I book a refundable accommodation in Santa María Centro?
If you need the flexibility to change your travel plans to Santa María Centro, most properties provide refundable* rates you can book. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa María Centro be like during my visit?
January and December are typically the warmest months in Santa María Centro when the average temp is 77°F. July and June are the coldest months when the average temperature is 57°F. February and December are the months with the most rain.
Why should I book my Santa María Centro accommodation with Hotels.com?
There are lots of reasons to book your Santa María Centro trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring