Hotels in Mill Creek

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Where to stay in Mill Creek?

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

1. The Riverview

Cape Girardeau

$114

$129 total

includes taxes & fees

Sep 28 - Sep 29

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

2. Drury Inn & Suites Cape Girardeau

Cape Girardeau

$90

$102 total

includes taxes & fees

Oct 9 - Oct 10

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

3. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

$100

$113 total

includes taxes & fees

Sep 28 - Sep 29

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

4. Pear Tree Inn Cape Girardeau West

Cape Girardeau

$72

$81 total

includes taxes & fees

Sep 28 - Sep 29

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A spacious living room with a sofa set, a coffee table, and a dining area.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

A lobby with seating areas, a reception desk, and a bar.

5. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

$130

$147 total

includes taxes & fees

Oct 4 - Oct 5

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

6. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

$101

$115 total

includes taxes & fees

Sep 27 - Sep 28

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

An outdoor patio with stone walls, wicker furniture, and large windows.

7. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

$106

$119 total

includes taxes & fees

Oct 4 - Oct 5

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

8. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

$101

$114 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

A bathroom with a marble wall and a white bathtub.

9. Town House Inn Cape Giradreau

Cape Girardeau

$75

$88 total

includes taxes & fees

Sep 25 - Sep 26

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

10. Quality Inn Cape Girardeau North

Cape Girardeau

$60

$68 total

includes taxes & fees

Oct 4 - Oct 5

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

11. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

$88

$105 total

includes taxes & fees

Oct 4 - Oct 5

A rustic lodge with a steeply pitched roof, a central entrance with a door, and a porch with multiple lights.

A stone building with a patio area, string lights, and outdoor seating.

A cozy living room with a brown leather sofa, a wooden coffee table, and a window with a view of trees.

A cozy log cabin interior with a wooden staircase, a cushioned sofa, a small table, and a lamp.

12. Makanda Inn

Makanda

$262

$299 total

includes taxes & fees

Sep 27 - Sep 28

View all properties

Go beyond your typical stay in Mill Creek

Check out reviews of Mill Creek hotels guests love

The Riverview

Cape Girardeau

10/10 Exceptional

Mark

Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

10/10 Exceptional

Keri

Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

10/10 Exceptional

Janet

Drury Inn & Suites Cape Girardeau

Cape Girardeau

10/10 Exceptional

StephM

Pear Tree Inn Cape Girardeau West

Cape Girardeau

10/10 Exceptional

Kimberly

Frequently Asked Questions

What accommodations do travelers recommend in Mill Creek?

Guests like Hotel 7 Inn Anna.

Can I book a refundable hotel in Mill Creek?

If you're looking for the flexibility to change your travel plans to Mill Creek, most properties offer refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Mill Creek be like during my trip?

July and August are typically the warmest months in Mill Creek when the average temp is 75°F. January and February are the coldest months when the average temperature is 39°F. April and March are the months with the most rain.

Why should I book my Mill Creek hotel with Hotels.com?

There are lots of reasons to book your Mill Creek trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.