Hotels in San Luis

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight
Aug 25 - Aug 26
Tomorrow
Aug 26 - Aug 27
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

Top 5 hotels in San Luis at a glance

Where to stay in San Luis?

1. La Fuente Inn & Suites

La Fuente Inn & Suites
Yuma
$89
$98 total
includes taxes & fees
Aug 26 - Aug 27
La Fuente Inn & Suites

2. Everhome Suites Yuma East I-8 by Choice Hotels

Everhome Suites Yuma East I-8 by Choice Hotels
Yuma
$110
$121 total
includes taxes & fees
Sep 2 - Sep 3
Everhome Suites Yuma East I-8 by Choice Hotels

3. Motel 6 Yuma, AZ - East

Motel 6 Yuma, AZ - East
Yuma
$33
$36 total
includes taxes & fees
Sep 7 - Sep 8
Motel 6 Yuma, AZ - East

4. Extended Stay America Premier Suites - Yuma

Extended Stay America Premier Suites - Yuma
Yuma
$64
$71 total
includes taxes & fees
Aug 26 - Aug 27
Extended Stay America Premier Suites - Yuma

5. Yuma Inn & Suites

Yuma Inn & Suites
Yuma
$49
$54 total
includes taxes & fees
Aug 31 - Sep 1
Yuma Inn & Suites

6. Best Western Yuma Mall Hotel & Suites

Best Western Yuma Mall Hotel & Suites
Yuma
$73
$81 total
includes taxes & fees
Aug 28 - Aug 29
Best Western Yuma Mall Hotel & Suites

7. Best Western Plus Yuma Foothills Inn & Suites

Best Western Plus Yuma Foothills Inn & Suites
Yuma
$81
$87 total
includes taxes & fees
Sep 6 - Sep 7
Best Western Plus Yuma Foothills Inn & Suites

8. Quality Inn & Suites Yuma

Quality Inn & Suites Yuma
Yuma
$66
$72 total
includes taxes & fees
Aug 28 - Aug 29
Quality Inn & Suites Yuma

9. Radisson Hotel Yuma

Radisson Hotel Yuma
Yuma
$110
$121 total
includes taxes & fees
Sep 2 - Sep 3
Radisson Hotel Yuma

10. Wingate by Wyndham Yuma

Wingate by Wyndham Yuma
Yuma
$79
$87 total
includes taxes & fees
Aug 29 - Aug 30
Wingate by Wyndham Yuma

11. Residence Inn By Marriott Yuma

Residence Inn By Marriott Yuma
Yuma
$152
$168 total
includes taxes & fees
Aug 27 - Aug 28
Residence Inn By Marriott Yuma

12. Homewood Suites by Hilton Yuma

Homewood Suites by Hilton Yuma
Yuma
$93
$103 total
includes taxes & fees
Aug 28 - Aug 29
Homewood Suites by Hilton Yuma

13. Home2 Suites by Hilton Yuma Pivot Point

Home2 Suites by Hilton Yuma Pivot Point
Downtown Yuma
$106
$118 total
includes taxes & fees
Sep 6 - Sep 7
Home2 Suites by Hilton Yuma Pivot Point

14. Days Inn by Wyndham Yuma

Days Inn by Wyndham Yuma
Yuma
$56
$62 total
includes taxes & fees
Aug 28 - Aug 29
Days Inn by Wyndham Yuma

15. La Quinta Inn & Suites By Wyndham Yuma

La Quinta Inn & Suites By Wyndham Yuma
Yuma
$112
$123 total
includes taxes & fees
Aug 29 - Aug 30
La Quinta Inn & Suites By Wyndham Yuma

16. Ramada by Wyndham Yuma

Ramada by Wyndham Yuma
Yuma
$63
$69 total
includes taxes & fees
Aug 28 - Aug 29
Ramada by Wyndham Yuma

17. Four Points by Sheraton Yuma

Four Points by Sheraton Yuma
Yuma
$152
$168 total
includes taxes & fees
Sep 12 - Sep 13
Four Points by Sheraton Yuma

18. Comfort Inn & Suites Yuma I-8

Comfort Inn & Suites Yuma I-8
Yuma
$84
$89 total
includes taxes & fees
Aug 28 - Aug 29
Comfort Inn & Suites Yuma I-8

19. Super 8 by Wyndham Yuma

Super 8 by Wyndham Yuma
Yuma
$47
$52 total
includes taxes & fees
Sep 17 - Sep 18
Super 8 by Wyndham Yuma

20. Howard Johnson by Wyndham Yuma

Howard Johnson by Wyndham Yuma
Yuma
$63
$69 total
includes taxes & fees
Sep 4 - Sep 5
Howard Johnson by Wyndham Yuma
View all properties

Top landmarks in San Luis

San Luis Lakes State Park

7.8/10 (76 reviews)
San Luis Lakes State Park is in the heart of San Luis, so why not stop by during your stay.
See properties

Learn more about San Luis

San Luis is well-known for its attractions such as Colorado River and San Luis Lakes State Park.

See all hotels in San Luis
A rugged desert landscape with prominent red rock formations and sparse green vegetation.

Check out reviews of San Luis hotels guests love

Radisson Hotel Yuma

Radisson Hotel Yuma

10/10 Excellent
"Always wonderful! Great place to stay"
James 1-night trip
Posted 5 hours ago
Radisson Hotel Yuma
La Fuente Inn & Suites

La Fuente Inn & Suites

10/10 Excellent
"Wonderful hotel , early check in was great , staff was very helpful the overall stay was great, our hotel room very clean would recommend this hotel and planning to come back for a more extended stay"
Claudia 1-night trip
Posted 9 hours ago
La Fuente Inn & Suites
Rodeway Inn Yuma Downtown

Rodeway Inn Yuma Downtown

8/10 Good
"Broken ice machine"
elizabeth 1-night trip
Posted 2 days ago
Rodeway Inn Yuma Downtown
Best Western Yuma Mall Hotel & Suites

Best Western Yuma Mall Hotel & Suites

10/10 Excellent
"The rooms were clean with comfortable beds. They served a full breakfast with the staff being friendly and helpful. The pool was refreshing to enjoy during the day and evening. Front desk personal were friendly and we were even able to get in a couple of hours ahead of our check in time. Good location and clean surroundings."
Jacqueline 2-night trip
Posted 2 days ago
Best Western Yuma Mall Hotel & Suites
Ramada by Wyndham Yuma

Ramada by Wyndham Yuma

8/10 Good
"Clean Economical Convenient No breakfast to speak of No extras"
Robin 2-night trip
Posted 2 days ago
Ramada by Wyndham Yuma
Yuma Inn & Suites

Yuma Inn & Suites

10/10 Excellent
"staff is very friendly and helpful"
Molina 2-night trip
Posted 3 days ago
Yuma Inn & Suites
Days Inn by Wyndham Yuma

Days Inn by Wyndham Yuma

8/10 Good
"The staff was extremely friendly and helpful, and everything was clean. Unfortunately, the walls are paper-thin, and with the highway traffic and trucks frequently parking nearby, you can hear absolutely everything, which made it difficult for both me and my pet to relax. The pool area is small but nice to have, and the jacuzzi could definitely use an upgrade. As a platinum blonde, having heavily chlorinated water spraying directly onto the back of my hair was not exactly my idea of relaxation! 😂 Overall, wonderful staff, but the noise and thin walls were the biggest drawbacks."
Caridad 3-night trip
Posted 7 days ago
Days Inn by Wyndham Yuma

Frequently asked questions

Can I book refundable hotels in San Luis?
If you need the flexibility to change your plans to San Luis, most hotels provide refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in San Luis if I want a vacation rental instead of a hotel?
You'll find 5 vacation homes on our site.
What will the weather in San Luis be like during my vacation?
The warmest months in San Luis are usually July and August with an average temp of 92°F. December and January are the chilliest months when the average temp is 61°F. The rainiest months are September and August.
Why should I book my San Luis hotel through Hotels.com?
There are plenty of reasons to book your San Luis travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Keep exploring