Hotels in Mayo

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Where to stay in Mayo?

A modern breakfast area with a self-serve station, including yogurt, eggs, and milk options.

A conference room with a long table, blue chairs, framed artwork on the walls, and a sign for Holiday Inn Express.

A hotel room with two beds, a desk, and a view of the outdoors.

A reception desk with a modern design, a blue geometric wall pattern, and a wooden accent wall.

1. Holiday Inn Express Gaffney by IHG

Gaffney

$76

$83 total

includes taxes & fees

Nov 1 - Nov 2

A modern lobby with a blue sofa, a reception desk, and a large cityscape painting.

A hotel room with two beds, a nightstand, and a wall-mounted TV.

A modern restaurant with a bar area, large windows, and a kitchen visible in the background.

A Best Western Plus hotel with a parking lot and multiple cars parked in front.

2. Best Western Plus Spartanburg

Spartanburg

$87

$99 total

includes taxes & fees

Nov 1 - Nov 2

A hotel lobby with a bar area, seating with patterned upholstery, and a central coffee table.

A hotel reception desk with a 'Welcome to the Palmetto State' sign, a 'Manager On Duty' sign, and a 'Hilton Honors' sign.

A fitness center with treadmills, a bench, and exercise equipment.

A snack and beverage vending area with various snacks and drinks.

3. Hampton Inn Gaffney

Gaffney

$99

$107 total

includes taxes & fees

Nov 1 - Nov 2

A hotel lobby with a reception desk, a staircase, and a seating area with chairs.

A hotel entrance with a covered walkway, a pool area, and a sign for a spa.

A living room with a sofa, two armchairs, a coffee table, and a patterned rug.

A hotel dining area with multiple tables and chairs, a television mounted on a wall, and a kitchen area visible in the background.

4. Sleep Inn Gaffney at I-85

Gaffney

$59

$66 total

includes taxes & fees

Nov 22 - Nov 23

A modern bedroom with a large bed, a built-in TV, and a small desk.

A laundry room with three stacked washing machines, a power outlet, and a water heater.

A motel with multiple floors, balconies, and a parking lot.

A reception area with a modern design, including a large number '6' sign, a coffee machine, and a TV mounted on the wall.

5. Motel 6 Spartanburg, Sc – Northwest / Business 85

Spartanburg

$58

$64 total

includes taxes & fees

Nov 15 - Nov 16

A modern lobby with a reception desk, seating area, and a television screen.

A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.

A swimming pool with lounge chairs and tables, surrounded by brick buildings and a covered seating area.

6. Best Western Spartanburg I-26

Spartanburg

$93

$103 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a desk, a refrigerator, a television, and a bathroom visible through an arched doorway.

A hotel kitchen with a buffet setup, including a coffee station, a refrigerator, and a microwave.

A modern bathroom with a large bathtub, a chair, and a floor lamp.

A hotel with a well-lit entrance, multiple parking spaces, and a clear view of the sky.

7. Comfort Inn & Suites Spartanburg North

Spartanburg

$84

$93 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with two beds, a desk, a chair, and a large window with autumn foliage artwork.

A self-service coffee station with a Folgers Select Brew coffee maker and a vintage-themed beverage dispenser.

A spacious indoor area with a large glass door leading outside, a ceiling fan, and a counter with various items.

A hotel room with a wooden desk, a black chair, a small refrigerator, a microwave, and a TV on the wall.

8. Days Inn by Wyndham Spartanburg Waccamaw

Spartanburg

$60

$67 total

includes taxes & fees

Nov 1 - Nov 2

A lobby with a leather sofa, two lamps, a painting, and potted plants.

A swimming pool with a brick border and a metal ladder, surrounded by a fence and a house in the background.

A hotel lobby with a reception desk, a waiting area with a chair, and a large window providing a view of the outside.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom visible through an open door.

9. Quality Inn Gaffney I-85

Gaffney

$47

$53 total

includes taxes & fees

Nov 25 - Nov 26

A hotel reception area with a digital sign indicating free Wi-Fi availability.

A restaurant with red chairs and a counter with food items.

A hotel room with a bed, a TV, a desk, and a microwave.

A hotel entrance with a brick facade, a covered entrance area, and a parking lot.

10. Red Roof Inn Gaffney

Gaffney

$66

$74 total

includes taxes & fees

Oct 31 - Nov 1

A Holiday Inn Express & Suites hotel with a covered entrance and multiple stories.

A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a desk with a chair, and a large window.

A hotel reception area with a modern design, featuring a reception desk, two seating areas with chairs, and a wall-mounted artwork.

A buffet with various food items, including omelets and other dishes, displayed in stainless steel chafing dishes.

11. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Spartanburg

$114

$127 total

includes taxes & fees

Nov 1 - Nov 2

A multi-level hotel lobby with seating areas, a fireplace, and a staircase.

A modern coffee bar with a glass display case, seating area with round tables and chairs, and a wooden ceiling.

A modern hotel building with a large glass facade, a covered entrance, and a sign reading "Four Points by Sheraton".

An indoor swimming pool with clear blue water, surrounded by lounge chairs and wooden panel walls.

12. Four Points by Sheraton Spartanburg

Spartanburg

$107

$119 total

includes taxes & fees

Nov 8 - Nov 9

A conference room with a long table, blue and orange chairs, and a reception desk in the background.

A gym with treadmills, elliptical machines, and weight machines.

A Hampton Inn hotel with a clear entrance, well-maintained lawn, and a flagpole.

A conference room with two desks, two chairs, and a small table.

13. Hampton Inn Spartanburg-North I-85

Spartanburg

$127

$141 total

includes taxes & fees

Nov 15 - Nov 16

A bar area with a variety of liquor bottles, glasses, and a counter with food items.

A multi-story hotel with a stone facade and multiple windows, featuring a parking lot and landscaped areas.

A clinical setting with medical equipment, a large mirror, and a window providing natural light.

14. Holiday Inn Spartanburg Northwest by IHG

Spartanburg

$101

$112 total

includes taxes & fees

Nov 1 - Nov 2

A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.

A spacious lobby with a high ceiling, chandeliers, a registration desk, and potted plants.

A grand hotel lobby with a marble staircase, ornate carpet, and large landscape paintings on the walls.

A modern kitchen with marble countertops, wooden shelves, and a wine station.

15. Spartanburg Marriott

Spartanburg

$118

$131 total

includes taxes & fees

Nov 8 - Nov 9

A modern living room with a fireplace, two sofas, and a coffee table.

A reception area with two wooden reception desks, a blue accent wall, and a mounted television.

A hotel room with two beds, a desk, a TV, and a window with curtains.

A modern gym with various exercise equipment, motivational wall graphics, and a large window offering a view of the outdoors.

16. Best Western Spartanburg Northwest

Spartanburg

$88

$100 total

includes taxes & fees

Nov 22 - Nov 23

A modern kitchen with a central island, equipped with a microwave, toaster, and coffee machine.

A hotel room with a desk, office chair, sofa, and a large wall art piece.

A hotel room with a bed, a gray sofa, two ottomans, a window with a view, and abstract artwork on the wall.

17. Comfort Suites At WestGate Mall

Spartanburg

$88

$98 total

includes taxes & fees

Nov 22 - Nov 23

A modern kitchen with wooden cabinets, a built-in oven, and a coffee station.

A reception area with wooden reception desks, framed artwork, and a white door.

A wooden gazebo with a metal roof, a bench, and a ramp leading up to it.

18. Days Inn by Wyndham Spartanburg

Boiling Springs

$77

$85 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor seating area with sofas, a fire pit, and string lights.

A self-service kiosk with a variety of snacks and beverages, a microwave, and a refrigerated display.

A modern interior with hanging chairs, tables, and a view of the parking lot.

A modern hotel with a multi-story structure, large windows, and a prominent vertical light strip.

19. Tru by Hilton Spartanburg

Spartanburg

$106

$117 total

includes taxes & fees

Nov 23 - Nov 24

A hotel with a prominent sign, multiple balconies, and well-lit windows.

A hotel room with a bed, a desk, a chair, a television, a dresser, and a framed picture on the wall.

A conference room with a table, chairs, a sofa, a wall-mounted light, and an air conditioning unit.

A reception area with a stone wall, a Red Roof Inn sign, a desk with a computer, a printer, and a cash register.

20. Red Roof Inn Spartanburg - I-85

Spartanburg

$65

$72 total

includes taxes & fees

Oct 27 - Oct 28

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Go beyond your typical stay in Mayo

Pet friendly

Pool

Family friendly

Check out reviews of Mayo hotels guests love

Comfort Suites At WestGate Mall

10/10 Excellent

"Much nicer facility than I expected given the price. Property looked sharp, room was good. Good hvac, lighting in room. Will stay there again."

Best Western Plus Spartanburg

10/10 Excellent

"Clean room, excellent parking, and spectacular breakfast!!"

Best Western Spartanburg I-26

8/10 Good

"The bed was very comfortable! Slept like a rock. The room was very cleanThe bathroom sink was located outside the bathroom, which I always hate. The breakfast had a little pancake maker and a yogurt machine. There were eggs and bacon. The eggs were cold though. Lots of juice options, toast and bagels. Would recommend"

Hilton Garden Inn Spartanburg

8/10 Good

"The hotel was nice and the staff was very polite and helpful."

Days Inn by Wyndham Spartanburg Waccamaw

10/10 Excellent

"GREAT BED CLEAN PROPERTY"

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

8/10 Good

"The staff was very helpful providing information about Spartanberg as it was our first trip to the area. Breakfast at the hotel provided good choices. The room was clean."

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

10/10 Excellent

"Good hotel, clean room, great breakfast"

Spartanburg Marriott

10/10 Excellent

"Staff was friendly and helpful. Room was clean. We decided to dine in the restaurant on the property and were pleasantly surprised with how good the food was. Overall a great experience."

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

8/10 Good

"Good stay"

Frequently asked questions

What accommodations do travelers recommend in Mayo?

Guests like Spartanburg Marriott, Holiday Inn Express Hotel & Suites Spartanburg-North by IHG and Best Western Spartanburg Northwest.

Can I book a refundable hotel in Mayo?

If you're looking for the flexibility to change your plans to Mayo, most hotels provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Mayo be like during my visit?

July and August are typically the warmest months in Mayo when the average temp is 77°F. January and February are the coldest months when the average temperature is 46°F. December and April are the months with the most rain.

Why should I book my Mayo accommodation with Hotels.com?

There are lots of reasons to book your Mayo trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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