Hotels in Mayo

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Where to stay in Mayo?

A hotel room with a blue sofa, a wooden coffee table, a bed with white linens, a desk with a chair, and a large window.

A hotel room with a bed, a blue sofa, a wooden coffee table, a desk with a chair, and a framed abstract painting on the wall.

A Holiday Inn Express & Suites hotel with a covered entrance and multiple stories.

A large indoor swimming pool with a diving board, multiple doors, and seating areas.

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Spartanburg

$101

$112 total

includes taxes & fees

Sep 6 - Sep 7

A conference room with a long table, blue and orange chairs, and a reception desk in the background.

A coffee station with labeled dispensers for hot water, decaf roast, light roast, and dark roast coffee.

A gym with treadmills, elliptical machines, and weight machines.

A conference room with two desks, two chairs, and a small table.

Hampton Inn Spartanburg-North I-85

Spartanburg

$106

$117 total

includes taxes & fees

Sep 7 - Sep 8

A hotel dining area with multiple tables and chairs, a television mounted on a wall, and a kitchen area visible in the background.

A living room with a sofa, two armchairs, a coffee table, and a patterned rug.

A hotel with a swimming pool, lounge chairs, and a covered seating area.

A hotel room with two beds, a desk with a TV, and a window with curtains.

Sleep Inn Gaffney at I-85

Gaffney

$67

$75 total

includes taxes & fees

Sep 21 - Sep 22

A modern lobby with a blue sofa, a reception desk, and a large cityscape painting.

A modern restaurant with a bar area, large windows, and a kitchen visible in the background.

A Best Western Plus hotel with a parking lot and multiple cars parked in front.

A gym with treadmills, dumbbells, and a wall with motivational words.

Best Western Plus Spartanburg

Spartanburg

$91

$103 total

includes taxes & fees

Sep 6 - Sep 7

A lobby with a leather sofa, two lamps, a painting, and potted plants.

A hotel room with two beds, a desk, a chair, a TV, and a bathroom visible through an open door.

A hotel lobby with a reception desk, a waiting area with a chair, and a large window providing a view of the outside.

A dining area with a high ceiling, wooden chairs, a table, and a kitchen area with a TV and food display.

Quality Inn Gaffney I-85

Gaffney

$50

$56 total

includes taxes & fees

Sep 27 - Sep 28

A modern lobby with a reception desk, seating area, and a television screen.

A modern restaurant with high tables and chairs, a counter with a coffee machine, and a patterned wall.

A hotel with a covered entrance, brick exterior, and a sign indicating it is a Best Western hotel.

A hotel room with two beds, a desk with a lamp, a chair, a patterned rug, and a large window.

Best Western Spartanburg I-26

Spartanburg

$93

$103 total

includes taxes & fees

Sep 7 - Sep 8

A hotel room with a bed, a TV, a desk, and a microwave.

A hotel with a parking lot and a covered walkway.

A restaurant with red chairs and a counter with food items.

A hotel reception area with a digital sign indicating free Wi-Fi availability.

Red Roof Inn Gaffney

Gaffney

$62

$70 total

includes taxes & fees

Sep 7 - Sep 8

A hotel room with a bed, a desk with a computer, a television, and a microwave.

A single-story motel with a flat roof, large windows, and a small porch area.

A bedroom with a bed, wooden headboard, bedside tables, and a ceiling light.

A room with two beds, each with a wooden headboard and a floral bedspread. There is a small wooden table beside the beds.

SUN AND SAND MOTEL

Spartanburg

$64

$71 total

includes taxes & fees

Sep 2 - Sep 3

A modern reception area with a counter, seating, and a bookshelf with various items.

A multi-story hotel with a stone facade and multiple windows, featuring a parking lot and landscaped areas.

A clinical setting with medical equipment, a large mirror, and a window providing natural light.

A swimming pool with a metal ladder, surrounded by red chairs and umbrellas, with a building in the background.

Holiday Inn Spartanburg Northwest by IHG

Spartanburg

$95

$105 total

includes taxes & fees

Sep 11 - Sep 12

University Inn

Shelby

$86

$97 total

includes taxes & fees

Sep 13 - Sep 14

A buffet with various food items, including omelets and cheese.

A reception desk with a modern design, a blue geometric wall pattern, and a wooden accent wall.

A modern lobby with a sofa, chairs, a desk, and a map mural on the wall.

A vending area with Coca-Cola and Sprite refrigerated drinks, a 'happy place' sign, and snack baskets on shelves.

Holiday Inn Express Gaffney by IHG

Gaffney

$81

$88 total

includes taxes & fees

Sep 13 - Sep 14

A hotel lobby with a bar area, seating with patterned upholstery, and a central coffee table.

A snack and beverage vending area with various snacks and drinks.

A hotel reception desk with a 'Welcome to the Palmetto State' sign, a 'Manager On Duty' sign, and a 'Hilton Honors' sign.

A fitness center with treadmills, a bench, and exercise equipment.

Hampton Inn Gaffney

Gaffney

$128

$139 total

includes taxes & fees

Sep 10 - Sep 11

A hotel lobby with a reception desk, green sofa, patterned armchairs, and a potted plant.

A kitchen with wooden cabinets, a black refrigerator, and a dining area with chairs and a table.

A motel with multiple rooms, a blue awning, and a red car parked in front.

A hotel room with a bed, desk, chair, television, and lamps.

Baymont by Wyndham Gaffney

Gaffney

$70

$78 total

includes taxes & fees

Sep 6 - Sep 7

A hotel room with two beds, a desk, a refrigerator, a television, and a bathroom visible through an arched doorway.

A modern bathroom with a large bathtub, a chair, and a floor lamp.

A hotel kitchen with a buffet setup, including a coffee station, a refrigerator, and a microwave.

A reception desk with a wooden finish, a clock, and two card readers.

Comfort Inn & Suites Spartanburg North

Spartanburg

$84

$93 total

includes taxes & fees

Sep 27 - Sep 28

A modern bedroom with a large bed, a built-in TV, and a small desk.

A modern bathroom with a shower, toilet, and sink.

A laundry room with three stacked washing machines, a power outlet, and a water heater.

A reception area with a modern design, including a large number '6' sign, a coffee machine, and a TV mounted on the wall.

Motel 6 Spartanburg, Sc – Northwest / Business 85

Spartanburg

$61

$68 total

includes taxes & fees

Oct 1 - Oct 2

A modern living room with a fireplace, two sofas, and a coffee table.

A hotel lobby with multiple seating areas, a reception desk, and a fireplace.

A reception area with two wooden reception desks, a blue accent wall, and a mounted television.

A hotel room with two beds, a desk, a TV, and a window with curtains.

Best Western Spartanburg Northwest

Spartanburg

$93

$105 total

includes taxes & fees

Sep 6 - Sep 7

A hotel with multiple floors, a prominent red sign, and well-lit entrance.

A modern hotel with a prominent sign, multiple balconies, and well-lit windows.

Red Roof Inn Spartanburg - I-85

Spartanburg

$65

$72 total

includes taxes & fees

Sep 7 - Sep 8

A hotel lobby with a curved outdoor seating area, a fire pit, and a pool.

A modern kitchen with marble countertops, wooden shelves, and a wine station.

A spacious lobby with a high ceiling, chandeliers, a registration desk, and potted plants.

A grand hotel lobby with a marble staircase, ornate carpet, and large landscape paintings on the walls.

Spartanburg Marriott

Spartanburg

$118

$131 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with a bed, desk, chair, TV, and a painting on the wall.

A conference room with rows of blue chairs, a carpeted floor, and a yellow wall.

A dining area with tables and chairs, a fireplace, and a bookshelf.

A reception area with a wooden reception desk, a blue sofa, a small table with a lamp, and a window with curtains.

Super 8 by Wyndham Gaffney

Gaffney

$56

$63 total

includes taxes & fees

Sep 15 - Sep 16

A reception area with wooden reception desks, framed artwork, and a white door.

A modern kitchen with wooden cabinets, a built-in oven, and a coffee station.

A modern lobby with a large white reception desk, brown leather sofas, a round coffee table, and a ceiling light fixture.

Days Inn by Wyndham Spartanburg

Boiling Springs

$78

$87 total

includes taxes & fees

Sep 13 - Sep 14

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Go beyond your typical stay in Mayo

Pet friendly

Pool

Family friendly

Check out reviews of Mayo hotels guests love

Four Points by Sheraton Spartanburg

10/10 Excellent

"Liked a large workout room. Furnishings were dated."

Spartanburg Marriott

10/10 Excellent

"From the first moment, we were impressed with the property. The common areas are clean. The registration representative was friendly and personable. All questions were answered. The room was clean with a great view. the location was perfect for our event. We went to see "Backbone" at the Chapman Cultural Arts center less than a mile away. The streets were quiet and we felt safe walking to and from the event after 9pm. Very happy with choice and will visit again."

ECHO Suites Extended Stay by Wyndham Spartanburg

8/10 Good

"Location was real good"

Days Inn by Wyndham Spartanburg Waccamaw

10/10 Excellent

"Affordable and price friendly"

Best Western Spartanburg Northwest

10/10 Excellent

"I can think of nothing bad about this hotel except there needs to be a street sign so you don't miss it five times like we did....lol"

Comfort Suites At WestGate Mall

8/10 Good

"None"

University Inn

8/10 Good

"N/A"

Tru by Hilton Spartanburg

10/10 Excellent

"Robert was so helpful! What a great representative of the property. Clean, spacious, convenient!"

Hampton Inn Gaffney

10/10 Excellent

"The staff were very courteous and friendly. Our room was clean and comfortable. We slept well for about 9 hours!!! Before checking out we had breakfast. Hampton Inn has the best Breakfast Selection- #1 in our book!!! Keep up the great customer service! Awesome!!!!"

Frequently asked questions

What accommodations do travelers recommend in Mayo?

Guests like Holiday Inn Express Hotel & Suites Spartanburg-North by IHG, Best Western Spartanburg Northwest and Spartanburg Marriott.

Can I book a refundable hotel in Mayo?

If you're looking for the flexibility to change your plans to Mayo, most hotels provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Mayo be like during my visit?

July and August are typically the warmest months in Mayo when the average temp is 77°F. January and February are the coldest months when the average temperature is 46°F. December and April are the months with the most rain.

Why should I book my Mayo accommodation with Hotels.com?

There are lots of reasons to book your Mayo trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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