Hotels in Greencastle

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Check prices for these dates

Tonight
Dec 27 - Dec 28
Tomorrow
Dec 28 - Dec 29
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

Where to stay in Greencastle?

Lobby
Hampton Inn Kirksville
Hampton Inn Kirksville
2.5 star property
9.2 out of 10, Wonderful, (577)
  • cleanliness
    Relax in Kirksville with a pool, state park access, and free perks.
The price is $121
$138 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hampton Inn Kirksville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Check out reviews of Greencastle hotels guests love

Hampton Inn Kirksville

Hampton Inn Kirksville

10/10 Excellent
"Breakfast was great. "
Tina Rose 2-night trip
Posted 6 hours ago
Hampton Inn Kirksville

Frequently asked questions

Can I book a refundable hotel in Greencastle?
If you're looking for the flexibility to change your plans to Greencastle, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Greencastle be like during my vacation?
July and August are typically the warmest months in Greencastle when the average temp is 73°F. January and February are the coldest months when the average temperature is 32°F. May and June are the months with the most rain.
Why should I book my Greencastle hotel through Hotels.com?
There are lots of reasons to book your Greencastle trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.