A wooden viewing platform overlooking a mountainous landscape with a prominent volcano in the distance.

Hotels in San Mateo Milpas Altas

Q: What hotels do travelers recommend in San Mateo Milpas Altas?

Guests like Hotel Museo Spa Casa Santo Domingo , Hotel Camino Real Antigua and Hotel Soleil La Antigua .

Where to?

Dates

November 2026

December 2026

I'm traveling for business

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Where to stay in San Mateo Milpas Altas?

A wooden deck with a hot tub and a bench, overlooking a mountainous landscape.

1. Cabañas Casa Realeza

Antigua Guatemala

$356 total

includes taxes & fees

Nov 5 - Nov 6

A multi-story hotel atrium with a central column, balconies with plants, and seating areas with cushions.

2. Tikal Futura Hotel & Convention Center

Zona 11

$135 total

includes taxes & fees

Nov 22 - Nov 23

A corridor with a bench, potted plants, and a hanging light fixture.

3. Nico Hotel

Antigua Guatemala

$78 total

includes taxes & fees

Dec 2 - Dec 3

A yellow building with a clock tower and an archway.

4. Hotel Convento Santa Catalina

Historic Center

$81 total

includes taxes & fees

Nov 30 - Dec 1

A spacious courtyard with red chairs and tables, surrounded by lush greenery and potted plants.

5. El Carmen Hotel

Historic Center

$134 total

includes taxes & fees

Dec 1 - Dec 2

An indoor swimming pool with a stone floor and brick walls, featuring a green wall with a mosaic design at the far end.

6. Le Suisse Spa

Santa Lucía Milpas Altas

$99 total

includes taxes & fees

Nov 5 - Nov 6

A garden pathway leading to a building with a green lawn and a clear blue sky.

7. Hotel Soleil La Antigua

Antigua Guatemala

$150 total

includes taxes & fees

Dec 1 - Dec 2

A covered outdoor seating area with wicker furniture and hanging lights.

8. Ciel-Luxe Hotels

Historic Center

$103 total

includes taxes & fees

Nov 12 - Nov 13

A lush garden with a rock waterfall, potted plants, and a well-maintained lawn.

9. Hotel Camelias Inn by AHS

Historic Center

$81 total

includes taxes & fees

Nov 30 - Dec 1

10. Hotel Genessis

Antigua Guatemala

$119 total

includes taxes & fees

Nov 11 - Nov 12

A corridor with yellow walls, potted plants, and a tiled floor leading to a door.

11. Hotel Casa Antigua by AHS

Historic Center

$86 total

includes taxes & fees

Dec 2 - Dec 3

A stone-walled corridor with steps leading to a wooden door, surrounded by lush greenery and potted plants.

12. Hotel Museo Spa Casa Santo Domingo

Barrio de La Concepción

$436 total

includes taxes & fees

Nov 9 - Nov 10

A courtyard with a spiral staircase, potted plants, and rustic furniture.

13. Hotel Casa Anturio

Historic Center

$67 total

includes taxes & fees

Nov 8 - Nov 9

An outdoor pool area with wooden decking, surrounded by lush greenery and potted plants.

14. Porta Hotel Antigua

Antigua Guatemala

$237 total

includes taxes & fees

Nov 9 - Nov 10

A corridor with tiled flooring, wooden benches, and potted plants.

15. Hotel Meson del Valle by AHS

Antigua Guatemala

$69 total

includes taxes & fees

Nov 25 - Nov 26

An interior courtyard with brick arches, a stone wall, and hanging plants.

16. La Capitania de San Pedro

Antigua Guatemala

$73 total

includes taxes & fees

Nov 5 - Nov 6

A multi-level outdoor garden with potted plants and a wooden pergola structure.

17. Naif Boutique Hotel

Historic Center

$110 total

includes taxes & fees

Nov 18 - Nov 19

A courtyard with potted plants, a dining area with tables and chairs, and a staircase leading to an upper level.

18. Hotel La Galeria

Historic Center

$71 total

includes taxes & fees

Nov 22 - Nov 23

A conservatory with a large window, a stone bench, and two chairs with cushions.

19. Meson Panza Verde

Antigua Guatemala

$168 total

includes taxes & fees

Nov 18 - Nov 19

A covered outdoor area with stone flooring, potted plants, and a wooden pergola.

20. San Rafael Hotel

Historic Center

$256 total

includes taxes & fees

Nov 30 - Dec 1

View all properties

Go beyond your typical stay in San Mateo Milpas Altas

Top landmarks in San Mateo Milpas Altas

La Azotea Cultural Center

La Azotea Cultural Center is in the heart of San Mateo Milpas Altas, so why not stop by during your stay. If you have fun at La Azotea Cultural Center, you'll love Hobbitenango and House of the Giants, both located nearby.

See properties

Learn more about San Mateo Milpas Altas

The region around San Mateo Milpas Altas is home to attractions such as La Azotea Cultural Center and Casa Santo Domingo Museum.

See all hotels in San Mateo Milpas Altas

Check out reviews of San Mateo Milpas Altas hotels guests love

San Rafael Hotel

Historic Center

10/10 Exceptional

I cannot imagine a better place to stay in Antigua. A few hundred yards from the famous Antigua Arch, the staff was above and beyond expectations 24/7. They found us a Mayan tour guide for the city walk and the next day out to the Iximché Ruins, we saw an actual Mayan ritual by people doing their way if life - ie not a show for tourists. There weren’t any there. Back at Hotel Rafael, Ray and his partner built a little piece of perfection from excellent breakfasts, indoor ponds, and...

Jay

Hotel Museo Spa Casa Santo Domingo

Barrio de La Concepción

10/10 Exceptional

Matthew

Porta Hotel Antigua

Antigua Guatemala

10/10 Exceptional

The property is beautiful. Well maintained and the common areas (restaurant, pool, bar, gym) are large, well appointed and comfortable. Our rroom and bathroom were incredibly clean. The best part, though, was the staff at the front desk - in particular, Emanuel. He was incredibly helpful - helping us change to a quieter room, arranging for shuttles, meals to go, and gave good advice on where to eat. He is a great representative for the hotel, and we really appreciated his responsiveness to our...

Kenneth

Le Suisse Spa

Santa Lucía Milpas Altas

10/10 Exceptional

Hoy tuve la oportunidad de visitar Le Suisse Spa con mi prometida, y la experiencia fue excelente. Desde el inicio, nos hicieron sentir bienvenidos y disfrutamos de una estadía realmente cómoda. Cenamos en el restaurante Mil Luces y quedamos encantados. Las pastas son una delicia, en especial una que probamos con un queso increíblemente sabroso, totalmente recomendada. Además, pedimos la oferta de botella de vino con tabla de quesos como entrada, y todo estaba espectacular. Después, visitamos...

Brayan

A modern, triangular wooden structure with a glass entrance, surrounded by lush greenery.

Santo Cielo by Casa Santo Domingo

Antigua Guatemala

10/10 Exceptional

First you have to check in, in Hotel Santo Domingo, you can park in their parking at no cost, but you should give them your parking ticket while cheking in Then you can take their shuttle to tenedor del cerro or take your car to tenedor del cerro parking, they are going to be waiting for you in a golf cart to take you to your Camp site They told me that is the same rate if you stay in a camp for 2 or 4 We stay in an old road house restaurated to be a 5 star camping, a lot pf privacy, jacuzzi...

jerry

A garden with a pergola, potted plants, and a chair.

Casa Santa Rosa Hotel Boutique

Historic Center

10/10 Exceptional

Maile

A bedroom with a four-poster bed, two armchairs, a desk, and a nightstand.

El Convento Boutique Hotel

Historic Center

10/10 Exceptional

Steven

A hallway with a wooden reception desk, potted plants, and a tiled floor.

Casa Noble Hotel

Antigua Guatemala

10/10 Exceptional

Sarah Elizabeth

Hotel La Galeria

Historic Center

10/10 Exceptional

Roshani

Meson Panza Verde

Antigua Guatemala

10/10 Exceptional

Brandon

Hotel Genessis

Antigua Guatemala

10/10 Exceptional

Sandra

A multi-level interior with a staircase, wooden beams, and hanging light fixtures.

Hotel Casa Colonial by AHS

Historic Center

10/10 Exceptional

Patricia

A corridor with arches, tiled flooring, and potted plants.

Hotel Las Farolas

Antigua Guatemala

10/10 Exceptional

Sasithorn

Frequently Asked Questions

What hotels do travelers recommend in San Mateo Milpas Altas?

Guests like Hotel Museo Spa Casa Santo Domingo, Hotel Camino Real Antigua and Hotel Soleil La Antigua.

Can I book a refundable hotel in San Mateo Milpas Altas?

If you want the flexibility to change your travel plans to San Mateo Milpas Altas, most hotels provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

Where can I stay in San Mateo Milpas Altas if I want a vacation rental instead of a traditional hotel?

If you want to find a good alternative to a hotel, review our selection of 6 vacation homes.

What will the weather in San Mateo Milpas Altas be like during my trip?

The warmest months in San Mateo Milpas Altas are usually April and March with an average temp of 67°F. January and December are the chilliest months when the average temp is 64°F. The rainiest months are September and June.

Why should I book my San Mateo Milpas Altas hotel with Hotels.com?

There are plenty of reasons to book your San Mateo Milpas Altas travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.