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Hotels in Dona Ana

November 2026
December 2026

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This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Where to stay in Dona Ana?

A multi-story building with a stone facade, a central entrance with a wooden archway, and a blue car parked in front.
A restaurant with a bar area, wooden chairs, a round table, and wall art.
A swimming pool with a curved edge, surrounded by palm trees and a building with a tiled roof.
An outdoor patio with stone pillars, green chairs, and a table.

1. Staybridge Suites Las Cruces by IHG

Staybridge Suites Las Cruces by IHG
Las Cruces
$115
$133 total
includes taxes & fees
Oct 25 - Oct 26
Staybridge Suites Las Cruces by IHG
A modern breakfast bar with a coffee machine, cereal and fruit options, and a yogurt, eggs, and milk dispenser.
A hotel room with a blue sofa, a wooden coffee table, two beds with white bedding, a headboard with a blue accent, a framed picture on the wall, and a window with a geometric blind.
A large, modern building with a curved roof and large glass windows, likely a hotel or conference center.
A modern hotel lobby with a wooden ceiling, a seating area with a sofa and chairs, a small table with a computer, and a decorative wall with a map design.

2. Holiday Inn Express & Suites Las Cruces North by IHG

Holiday Inn Express & Suites Las Cruces North by IHG
Las Cruces
$127
$147 total
includes taxes & fees
Oct 25 - Oct 26
Holiday Inn Express & Suites Las Cruces North by IHG
A hotel room with two beds, a television, a desk, and a window with curtains.
A hotel room with a large bed, two bedside lamps, a desk with a chair, a window with curtains, and a cityscape painting on the wall.
A hotel with a stone facade, a covered entrance, and a parking lot.
A hotel lobby with a reception desk, seating area, and a ceiling fan.

3. Super 8 by Wyndham Las Cruces/White Sands Area

Super 8 by Wyndham Las Cruces/White Sands Area
Las Cruces
$51
$60 total
includes taxes & fees
Nov 6 - Nov 7
Super 8 by Wyndham Las Cruces/White Sands Area
An outdoor seating area with a fire pit, sofas, and chairs.
A modern cafe with an 'inspired table' sign, a 'good morning' greeting, and a variety of seating options including tables and chairs.
A modern hotel room with a large bed, a desk with a computer, a television, and a kitchenette.
A modern lounge area with a sofa, chairs, and tables, featuring pendant lighting and large windows.

4. Home2 Suites by Hilton Las Cruces

Home2 Suites by Hilton Las Cruces
Las Cruces
$124
$143 total
includes taxes & fees
Nov 15 - Nov 16
Home2 Suites by Hilton Las Cruces
A compact hotel room with a desk, chair, television, and a microwave.
A motel with a large '6' sign, indoor pool, spa, and suites.
A hotel room with two beds, a desk, and a chair.
A reception area with a counter, seating, and a view through glass doors.

5. Motel 6 Las Cruces, NM - Telshor

Motel 6 Las Cruces, NM - Telshor
Las Cruces
$56
$66 total
includes taxes & fees
Oct 20 - Oct 21
Motel 6 Las Cruces, NM - Telshor
An outdoor patio area with wicker furniture, a barbecue grill, and a stone wall.
A breakfast bar with a red wall, wooden cabinets, and various breakfast items.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A pool area with blue chairs and a no diving sign.

6. Towneplace Suites by Marriott Las Cruces

Towneplace Suites by Marriott Las Cruces
Las Cruces
$116
$134 total
includes taxes & fees
Nov 15 - Nov 16
Towneplace Suites by Marriott Las Cruces
A pool area with a hot tub, lounge chairs, and a lifeguard stand.
A spacious living area with a fireplace, a television mounted above it, and a seating arrangement including a sofa and chairs.
A hotel with a modern design, featuring a covered entrance and multiple floors.
A hotel room with a blue accent wall, a sofa, a bed, a desk, and a mirror.

7. Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North
Las Cruces
$103
$123 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Suites Las Cruces I-25 North
A spacious lobby with a high ceiling, a central chandelier, and large windows allowing natural light.
A breakfast buffet with various food items, including fruits, pastries, and hot beverages.
A spacious living room with a fireplace, leather sofas, a wooden coffee table with fruit, and patterned rugs.
An outdoor patio with a built-in fireplace, surrounded by yellow cushioned chairs and a pergola overhead.

8. Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
Las Cruces
$111
$129 total
includes taxes & fees
Oct 31 - Nov 1
Hilton Garden Inn Las Cruces
A hotel lobby with a 'Connect & Print' service area, a fireplace, and a seating area with blue chairs.
A modern office space with multiple desktop computers, a coffee machine, and a colorful carpet.
A lobby with a stone wall, a fireplace, and blue chairs.
A hallway with two refrigerated beverage dispensers stocked with various drinks and snacks.

9. Fairfield Inn by Marriott Las Cruces

Fairfield Inn by Marriott Las Cruces
Las Cruces
$129
$152 total
includes taxes & fees
Nov 1 - Nov 2
Fairfield Inn by Marriott Las Cruces
A spacious lobby with a central dining area, multiple seating options, and a modern chandelier.
A gym with treadmills, elliptical machines, and exercise bikes.
A hotel with a modern facade, multiple parking spaces, and a well-lit entrance.
A lobby with teal armchairs, a coffee bar, and a dining area.

10. Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
Las Cruces
$118
$136 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn & Suites Las Cruces I-10
A Days Inn with a large sign, a flag, and a well-maintained entrance area.
An outdoor patio with wooden benches and a grill area.
A hotel lobby with a reception desk, seating area, and a kitchenette.
A breakfast bar with coffee machines, a fruit bowl, and stacked paper cups.

11. Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces
Las Cruces
$48
$57 total
includes taxes & fees
Nov 1 - Nov 2
Days Inn by Wyndham Las Cruces
A hotel room with two beds, a desk with a TV, a chair, and two lamps.
A kitchen with a wooden counter, coffee machines, a microwave, and various appliances.
A multi-story hotel with a central entrance, balconies, and a parking area.
A lobby with a reception desk, American flag, and a green carpet with 'Quinta Suites' logo.

12. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Las Cruces
$59
$69 total
includes taxes & fees
Nov 1 - Nov 2
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
A buffet area with a variety of baked goods, a coffee station, and a decorative plant.
Lobby
A hotel room with two beds, wooden benches, a desk, and a chair.
A cozy living room with a wooden sofa and armchair, a wooden coffee table, and a patterned rug.

13. Best Western Mission Inn

Best Western Mission Inn
Las Cruces
$80
$93 total
includes taxes & fees
Oct 21 - Oct 22
Best Western Mission Inn
A lobby with a stone fireplace, sofas, and a glass coffee table.
A living room with a sofa, ottoman, TV, and a desk with a chair. There is a kitchen in the background.
A spacious indoor dining area with high ceilings, large windows, and a variety of seating options including tables and booths.
An indoor swimming pool with a hot tub, tiled flooring, and a high ceiling with beams.

14. Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
Las Cruces
$106
$123 total
includes taxes & fees
Oct 25 - Oct 26
Drury Inn & Suites Las Cruces
A pool area with a fountain, palm trees, and outdoor seating.
A fountain with a lotus design in a pool, surrounded by a balustrade and palm trees.
A hallway with a tiled floor, a chandelier, potted plants, and a cross at the end.
A brick pathway lined with lush greenery and stone columns, leading to a covered area with a pergola.

15. Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
Las Cruces
$119
$164 total
includes taxes & fees
Nov 1 - Nov 2
Hotel Encanto de Las Cruces
A vending machine, a refrigerator, and a display of travel brochures.
A motel with a large sign displaying the number 6, indicating it is the sixth motel in a chain.
A coffee machine with a coffee cup and a sign above it that says "RISE & SHINE".
A hotel room with two beds, a refrigerator, a desk with a chair, a mirror, and a window with curtains.

16. Studio 6 – Las Cruces, NM - Telshor

Studio 6 – Las Cruces, NM - Telshor
Las Cruces
$59
$69 total
includes taxes & fees
Oct 20 - Oct 21
Studio 6 – Las Cruces, NM - Telshor
A spacious hotel lobby with a long reception desk, multiple seating areas, and large windows allowing natural light.
A spacious living area with a fireplace, comfortable seating, and a television.
A reception desk with a marble top, framed pictures on the wall, a lamp, and a sign that reads "welcome to Las Cruces."
A swimming pool with lounge chairs and a sunshade.

17. Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25
Las Cruces
$114
$132 total
includes taxes & fees
Oct 29 - Oct 30
Hampton Inn & Suites Las Cruces I-25
Two adjacent beds with white bedding, a bedside table with a lamp, and a painting on the wall.
A swimming pool with lounge chairs and a building with a red-tiled roof in the background.
A hotel with a signboard, arched windows, and a clear sky.
A spacious lobby with a tiled floor, a reception desk, and a staircase leading to upper floors.

18. Go2 By Relianse

Go2 By Relianse
Las Cruces
$53
$66 total
includes taxes & fees
Oct 24 - Oct 25
Go2 By Relianse
A reception area with a stone counter, a clock, and a decorative plant.
A spacious lobby with a stone column, a clock, and a view of the outside.
A neatly made bed with white linens and a geometric-patterned blanket, a wooden chair, and a wardrobe in a room with dark walls and a light-colored floor.
A hotel room with a flat-screen TV mounted on the wall, a microwave, a refrigerator, a wooden dresser, and a bedside table with a cup and a trash bin.

19. Century 21 Motel

Century 21 Motel
Las Cruces
$55
$71 total
includes taxes & fees
Nov 18 - Nov 19
Century 21 Motel
A spacious hotel lobby with a modern design, featuring a reception desk, seating area, and potted plants.
A modern hotel room with a blue sofa, armchairs, a flat-screen TV, and framed pictures on the wall.
A hotel room with a bed, a sofa, a desk, and a TV. There are framed pictures on the wall.
A hotel room with a large bed, a desk, a chair, a flat-screen TV, and a window with curtains.

20. Comfort Suites University Las Cruces

Comfort Suites University Las Cruces
Las Cruces
$83
$97 total
includes taxes & fees
Nov 8 - Nov 9
Comfort Suites University Las Cruces
View all properties

Go beyond your typical stay in Dona Ana

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Spa
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Family friendly
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Check out reviews of Dona Ana hotels guests love

A modern breakfast bar with a coffee machine, cereal and fruit options, and a yogurt, eggs, and milk dispenser.
A hotel room with a blue sofa, a wooden coffee table, two beds with white bedding, a headboard with a blue accent, a framed picture on the wall, and a window with a geometric blind.
A large, modern building with a curved roof and large glass windows, likely a hotel or conference center.
A modern hotel lobby with a wooden ceiling, a seating area with a sofa and chairs, a small table with a computer, and a decorative wall with a map design.

Holiday Inn Express & Suites Las Cruces North by IHG

Holiday Inn Express & Suites Las Cruces North by IHG
Las Cruces

10/10 Exceptional

United States
Phil
Holiday Inn Express & Suites Las Cruces North by IHG
A multi-story building with a stone facade, a central entrance with a wooden archway, and a blue car parked in front.
A restaurant with a bar area, wooden chairs, a round table, and wall art.
A swimming pool with a curved edge, surrounded by palm trees and a building with a tiled roof.
An outdoor patio with stone pillars, green chairs, and a table.

Staybridge Suites Las Cruces by IHG

Staybridge Suites Las Cruces by IHG
Las Cruces

10/10 Exceptional

United States
Marcella
Staybridge Suites Las Cruces by IHG
An outdoor seating area with a fire pit, sofas, and chairs.
A modern cafe with an 'inspired table' sign, a 'good morning' greeting, and a variety of seating options including tables and chairs.
A modern hotel room with a large bed, a desk with a computer, a television, and a kitchenette.
A modern lounge area with a sofa, chairs, and tables, featuring pendant lighting and large windows.

Home2 Suites by Hilton Las Cruces

Home2 Suites by Hilton Las Cruces
Las Cruces

10/10 Exceptional

United States
FERNANDO
Home2 Suites by Hilton Las Cruces
A lobby with a stone fireplace, sofas, and a glass coffee table.
A living room with a sofa, ottoman, TV, and a desk with a chair. There is a kitchen in the background.
A spacious indoor dining area with high ceilings, large windows, and a variety of seating options including tables and booths.
An indoor swimming pool with a hot tub, tiled flooring, and a high ceiling with beams.

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
Las Cruces

10/10 Exceptional

United States
Robert
Drury Inn & Suites Las Cruces
An outdoor patio area with wicker furniture, a barbecue grill, and a stone wall.
A breakfast bar with a red wall, wooden cabinets, and various breakfast items.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A pool area with blue chairs and a no diving sign.

Towneplace Suites by Marriott Las Cruces

Towneplace Suites by Marriott Las Cruces
Las Cruces

10/10 Exceptional

United States
Marisa
Towneplace Suites by Marriott Las Cruces
A spacious lobby with a high ceiling, a central chandelier, and large windows allowing natural light.
A breakfast buffet with various food items, including fruits, pastries, and hot beverages.
A spacious living room with a fireplace, leather sofas, a wooden coffee table with fruit, and patterned rugs.
An outdoor patio with a built-in fireplace, surrounded by yellow cushioned chairs and a pergola overhead.

Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
Las Cruces

10/10 Exceptional

United States
Amy
Hilton Garden Inn Las Cruces
A spacious lobby with a central dining area, multiple seating options, and a modern chandelier.
A gym with treadmills, elliptical machines, and exercise bikes.
A hotel with a modern facade, multiple parking spaces, and a well-lit entrance.
A lobby with teal armchairs, a coffee bar, and a dining area.

Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
Las Cruces

10/10 Exceptional

United States
Anonymous traveler
Hampton Inn & Suites Las Cruces I-10
A pool area with a fountain, palm trees, and outdoor seating.
A fountain with a lotus design in a pool, surrounded by a balustrade and palm trees.
A hallway with a tiled floor, a chandelier, potted plants, and a cross at the end.
A brick pathway lined with lush greenery and stone columns, leading to a covered area with a pergola.

Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
Las Cruces

10/10 Exceptional

United States
Jeremy
Hotel Encanto de Las Cruces
A hotel lobby with a 'Connect & Print' service area, a fireplace, and a seating area with blue chairs.
A modern office space with multiple desktop computers, a coffee machine, and a colorful carpet.
A lobby with a stone wall, a fireplace, and blue chairs.
A hallway with two refrigerated beverage dispensers stocked with various drinks and snacks.

Fairfield Inn by Marriott Las Cruces

Fairfield Inn by Marriott Las Cruces
Las Cruces

10/10 Exceptional

United States
Shirley
Fairfield Inn by Marriott Las Cruces
A buffet area with a variety of baked goods, a coffee station, and a decorative plant.
Lobby
A hotel room with two beds, wooden benches, a desk, and a chair.
A cozy living room with a wooden sofa and armchair, a wooden coffee table, and a patterned rug.

Best Western Mission Inn

Best Western Mission Inn
Las Cruces

10/10 Exceptional

United States
Jamus
Best Western Mission Inn
A Days Inn with a large sign, a flag, and a well-maintained entrance area.
An outdoor patio with wooden benches and a grill area.
A hotel lobby with a reception desk, seating area, and a kitchenette.
A breakfast bar with coffee machines, a fruit bowl, and stacked paper cups.

Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces
Las Cruces

10/10 Exceptional

United States
Robert
Days Inn by Wyndham Las Cruces
A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.
A hotel room with a large bed, a television, a desk, and a chair.
A golf course with a mountain range in the background.
A hotel dining area with multiple tables and chairs, a coffee station, and a reception desk.

Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla
Las Cruces

10/10 Exceptional

United States
Rebecca
Comfort Inn & Suites Las Cruces Mesilla
A hotel room with two beds, a desk with a TV, a chair, and two lamps.
A kitchen with a wooden counter, coffee machines, a microwave, and various appliances.
A multi-story hotel with a central entrance, balconies, and a parking area.
A lobby with a reception desk, American flag, and a green carpet with 'Quinta Suites' logo.

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Las Cruces

10/10 Exceptional

United States
Wendy
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
A hotel room with a bed, a TV mounted on the wall, a desk, and a sofa.
A pool area with lounge chairs and umbrellas, surrounded by a fence and a building with multiple windows and balconies.
A compact kitchenette with a microwave, a small sink, and a refrigerator.
A modern hotel with a flat roof, large windows, and a well-lit entrance.

Springhill Suites By Marriott Las Cruces

Springhill Suites By Marriott Las Cruces
Las Cruces

10/10 Exceptional

United States
Cynthia
Springhill Suites By Marriott Las Cruces

Frequently Asked Questions

What hotels do travelers recommend in Dona Ana?

Guests like Hotel Encanto de Las Cruces, Ramada Hotel & Conference Center by Wyndham Las Cruces and La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain.

Can I book refundable hotels in Dona Ana?

If you want the flexibility to change your travel plans to Dona Ana, most accommodations provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Dona Ana be like during my visit?

June and July are typically the warmest months in Dona Ana when the average temp is 82°F. January and December are the coldest months when the average temperature is 48°F. August and September are the months with the most rain.

Why should I book my Dona Ana hotel through Hotels.com?

There are lots of reasons to book your Dona Ana trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.