
Hotels in Pamplico
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Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2237)
9.0/10
Wonderful
(2237)
The price is $85
$85
$95 total
includes taxes & fees
Jan 11 - Jan 12




Hyatt Place Florence Downtown
Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1010)
9.0/10
Wonderful
(1010)
The price is $100
$100
$112 total
includes taxes & fees
Jan 12 - Jan 13




Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2515)
8.6/10
Excellent
(2515)
The price is $70
$70
$79 total
includes taxes & fees
Jan 7 - Jan 8




Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1199)
9.2/10
Wonderful
(1199)
The price is $98
$98
$109 total
includes taxes & fees
Jan 25 - Jan 26




Best Western Inn
Best Western Inn
2.5 star property
Florence
7.6 out of 10, Good, (1011)
7.6/10
Good
(1011)
The price is $89
$89
$100 total
includes taxes & fees
Jan 7 - Jan 8




Spark by Hilton Florence North I-95, SC
Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
7.8 out of 10, Good, (36)
7.8/10
Good
(36)
The price is $97
$97
$112 total
includes taxes & fees
Jan 28 - Jan 29




Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1011)
8.6/10
Excellent
(1011)
The price is $114
$114
$128 total
includes taxes & fees
Jan 18 - Jan 19




La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
8.0 out of 10, Very Good, (1691)
8.0/10
Very Good
(1691)
The price is $94
$94
$105 total
includes taxes & fees
Jan 12 - Jan 13




The Inn at the Crossroads
The Inn at the Crossroads
2.0 star property
Lake City
9.4 out of 10, Exceptional, (838)
9.4/10
Exceptional
(838)
The price is $134
$134
$150 total
includes taxes & fees
Jan 20 - Jan 21




Days Inn by Wyndham Florence/I-95 North
Days Inn by Wyndham Florence/I-95 North
2.0 star property
Florence
6.8 out of 10, (1012)
6.8/10
(1012)
The price is $59
$59
$66 total
includes taxes & fees
Jan 12 - Jan 13




Hampton Inn & Suites Florence Center
Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (835)
9.0/10
Wonderful
(835)
The price is $98
$98
$109 total
includes taxes & fees
Jan 25 - Jan 26




Tru by Hilton Florence I-95
Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1007)
8.4/10
Very Good
(1007)
The price is $93
$93
$108 total
includes taxes & fees
Jan 12 - Jan 13




Comfort Suites Florence I-95
Comfort Suites Florence I-95
2.5 star property
Florence
8.4 out of 10, Very Good, (1005)
8.4/10
Very Good
(1005)
The price is $103
$103
$119 total
includes taxes & fees
Jan 11 - Jan 12




Quality Inn Mullins - Marion
Quality Inn Mullins - Marion
2.5 star property
Marion
7.8 out of 10, Good, (379)
7.8/10
Good
(379)
The price is $99
$99
$108 total
includes taxes & fees
Jan 12 - Jan 13




Florence Inn and Suites
Florence Inn and Suites
2.5 star property
Florence
6.4 out of 10, (330)
6.4/10
(330)
The price is $64
$64
$71 total
includes taxes & fees
Jan 8 - Jan 9




Fairfield Inn & Suites by Marriott Florence I-20
Fairfield Inn & Suites by Marriott Florence I-20
2.5 star property
Florence
9.0 out of 10, Wonderful, (570)
9.0/10
Wonderful
(570)
The price is $110
$110
$123 total
includes taxes & fees
Jan 11 - Jan 12




Holiday Inn Express & Suites Latta by IHG
Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.6 out of 10, Exceptional, (537)
9.6/10
Exceptional
(537)
The price is $132
$132
$144 total
includes taxes & fees
Jan 12 - Jan 13




Affordable Suites Florence
Affordable Suites Florence
2.5 star property
Florence
9.2 out of 10, Wonderful, (125)
9.2/10
Wonderful
(125)
The price is $77
$77
$86 total
includes taxes & fees
Jan 15 - Jan 16




TownePlace Suites by Marriott Florence
TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (718)
9.0/10
Wonderful
(718)
The price is $103
$103
$116 total
includes taxes & fees
Jan 11 - Jan 12




Super 8 by Wyndham Florence
Super 8 by Wyndham Florence
2.0 star property
Florence
7.0 out of 10, Good, (1004)
7.0/10
Good
(1004)
The price is $58
$58
$65 total
includes taxes & fees
Jan 12 - Jan 13
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Budget hotels in Pamplico and vicinity




7.0 out of 10, Good, (1004)
7.0/10
Good
(1004)
The price is $58
$58
$65 total
includes taxes & fees
Jan 12 - Jan 13




7.0 out of 10, Good, (324)
7.0/10
Good
(324)
The price is $55
$55
$61 total
includes taxes & fees
Jan 20 - Jan 21




7.4 out of 10, Good, (688)
7.4/10
Good
(688)
The price is $68
$68
$76 total
includes taxes & fees
Feb 2 - Feb 3




9.2 out of 10, Wonderful, (125)
9.2/10
Wonderful
(125)
The price is $77
$77
$86 total
includes taxes & fees
Jan 15 - Jan 16




8.6 out of 10, Excellent, (2515)
8.6/10
Excellent
(2515)
The price is $70
$70
$79 total
includes taxes & fees
Jan 7 - Jan 8




Quality Inn & Suites Florence Civic Center
Quality Inn & Suites Florence Civic Center2.5 star property
Florence
7.8 out of 10, Good, (1258)
7.8/10
Good
(1258)
The price is $79
$79
$88 total
includes taxes & fees
Jan 25 - Jan 26




9.0 out of 10, Wonderful, (2237)
9.0/10
Wonderful
(2237)
The price is $85
$85
$95 total
includes taxes & fees
Jan 11 - Jan 12




7.6 out of 10, Good, (1011)
7.6/10
Good
(1011)
The price is $89
$89
$100 total
includes taxes & fees
Jan 7 - Jan 8




8.4 out of 10, Very Good, (1007)
8.4/10
Very Good
(1007)
The price is $93
$93
$108 total
includes taxes & fees
Jan 12 - Jan 13




La Quinta Inn & Suites by Wyndham Florence
La Quinta Inn & Suites by Wyndham Florence3.0 star property
Florence
8.0 out of 10, Very Good, (1691)
8.0/10
Very Good
(1691)
The price is $94
$94
$105 total
includes taxes & fees
Jan 12 - Jan 13




7.8 out of 10, Good, (705)
7.8/10
Good
(705)
The price is $97
$97
$109 total
includes taxes & fees
Jan 18 - Jan 19




Comfort Inn & Suites Florence Center Area
Comfort Inn & Suites Florence Center Area2.5 star property
Florence
9.2 out of 10, Wonderful, (1199)
9.2/10
Wonderful
(1199)
The price is $98
$98
$109 total
includes taxes & fees
Jan 25 - Jan 26




9.0 out of 10, Wonderful, (835)
9.0/10
Wonderful
(835)
The price is $98
$98
$109 total
includes taxes & fees
Jan 25 - Jan 26




8.4 out of 10, Very Good, (661)
8.4/10
Very Good
(661)
The price is $98
$98
$113 total
includes taxes & fees
Jan 18 - Jan 19




Spark by Hilton Florence North I-95, SC
Spark by Hilton Florence North I-95, SC2.5 star property
Florence
7.8 out of 10, Good, (36)
7.8/10
Good
(36)
The price is $97
$97
$112 total
includes taxes & fees
Jan 28 - Jan 29




8.8 out of 10, Excellent, (495)
8.8/10
Excellent
(495)
The price is $99
$99
$111 total
includes taxes & fees
Jan 11 - Jan 12




8.6 out of 10, Excellent, (260)
8.6/10
Excellent
(260)
The price is $99
$99
$111 total
includes taxes & fees
Jan 18 - Jan 19




7.8 out of 10, Good, (379)
7.8/10
Good
(379)
The price is $99
$99
$108 total
includes taxes & fees
Jan 12 - Jan 13




9.0 out of 10, Wonderful, (1010)
9.0/10
Wonderful
(1010)
The price is $100
$100
$112 total
includes taxes & fees
Jan 12 - Jan 13




7.0 out of 10, Good, (167)
7.0/10
Good
(167)
The price is $100
$100
$112 total
includes taxes & fees
Jan 25 - Jan 26
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Pamplico
Pet friendly
Family friendly
Check out reviews of Pamplico hotels guests love

Tru by Hilton Florence I-95
10/10 Excellent
"My room was very spacious and clean and i enjoyed the surround sound tv and the floors and bathroom were clean. The staff was very nice."

Days Inn by Wyndham Florence/I-95 North
10/10 Excellent
"Clean rooms friendly staff"

La Quinta Inn & Suites by Wyndham Florence
10/10 Excellent
"Everything was as good as it could be for a 3-star hotel"

Home2 Suites by Hilton Florence, SC
10/10 Excellent
"Clean, comfortable room with great amenities close to several restaurants."

Park Inn by Radisson Florence, SC
10/10 Excellent
"The stay was beautiful "

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
10/10 Excellent
"Hotel is right off the highway, close to Buc-ee’s and the room was very spacious. Breakfast was fine with your standard staples. Front desk staff were very friendly and helpful."

Hilton Garden Inn Florence
10/10 Excellent
"Great spot for a quick visit with friends. Clean easy access to food and activities "

Hampton Inn & Suites Florence Center
10/10 Excellent
"Staff is AMAZING there! From check in to housekeeping and the best complimentary breakfast we have had ANYWHERE. DEFINITELY our new place to stay halfway to Florida for the winter!!! Keep up the good work!"

Comfort Inn & Suites Florence Center Area
10/10 Excellent
"Fast check in, comfortable bed, quiet setting and a wonderful breakfast."
Frequently asked questions
Can I book refundable accommodations in Pamplico?
If you want the flexibility to change your plans to Pamplico, most hotels provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Pamplico be like during my vacation?
July and August are typically the warmest months in Pamplico when the average temp is 78°F. January and February are the coldest months when the average temperature is 50°F. August and July are the months with the most rain.
Why should I book my Pamplico hotel through Hotels.com?
There are lots of reasons to book your Pamplico trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.