Hotels in East Prairie
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Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (622 reviews)
cleanliness Gateway to historic Charleston with easy interstate access and free breakfast.
The price is $62
$69 total
includes taxes & fees
Jan 22 - Jan 23

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,000 reviews)
cleanliness Peaceful highway-adjacent retreat with indoor and outdoor pool options.
The price is $90
$103 total
includes taxes & fees
Jan 25 - Jan 26

Best Western Plus Sikeston
Best Western Plus SikestonSikeston
8.4 out of 10, Very Good, (1,004 reviews)
cleanliness Stay minutes from Central Park at this inviting hotel with an indoor pool and gym.
The price is $76
$86 total
includes taxes & fees
Jan 25 - Jan 26

Pear Tree Inn Sikeston
Pear Tree Inn SikestonSikeston
9.4 out of 10, Exceptional, (1,002 reviews)
cleanliness Quiet, dual pool paradise near Central Park in charming Sikeston.
The price is $75
$86 total
includes taxes & fees
Jan 25 - Jan 26

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very Good, (731 reviews)
cleanliness Enjoy a serene stay in Sikeston, just minutes from Central Park and Depot Museum.
The price is $58
$67 total
includes taxes & fees
Jan 22 - Jan 23

Comfort Inn & Suites Sikeston I-55
Comfort Inn & Suites Sikeston I-55Sikeston
8.4 out of 10, Very Good, (284 reviews)
cleanliness Cozy stay near Central Park with indoor pool, free WiFi, and friendly staff.
The price is $84
$96 total
includes taxes & fees
Jan 27 - Jan 28

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (463 reviews)
cleanliness Discover contemporary comfort with an indoor pool just off I-55 in Sikeston.
The price is $100
$113 total
includes taxes & fees
Feb 1 - Feb 2

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (50 reviews)
cleanliness Discover a modern retreat with a welcoming indoor pool and sip drinks at the bar.
The price is $101
$114 total
includes taxes & fees
Jan 29 - Jan 30

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,001 reviews)
cleanliness Enjoy a peaceful night's rest and complimentary breakfast at this quiet Sikeston hotel.
The price is $63
$72 total
includes taxes & fees
Jan 25 - Jan 26

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (447 reviews)
cleanliness Convenient stay near Central Park with refreshing pool and complimentary perks.
The price is $100
$113 total
includes taxes & fees
Jan 31 - Feb 1

Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner AreaSikeston
6.8 out of 10, (584 reviews)
cleanliness Convenient Sikeston escape with free amenities and easy access to local attractions.
The price is $59
$68 total
includes taxes & fees
Jan 22 - Jan 23

Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (105 reviews)
cleanliness Stay fit while visiting Charleston with a health club at this convenient motel.
The price is $60
$67 total
includes taxes & fees
Jan 22 - Jan 23

TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (12 reviews)
The price is $134
$152 total
includes taxes & fees
Jan 22 - Jan 23

Country Yard Inn and Suite
Country Yard Inn and SuiteSikeston
6.8 out of 10, (121 reviews)
cleanliness Enjoy a comfortable base in Sikeston with free perks and 24-hour service.
The price is $65
$77 total
includes taxes & fees
Jan 24 - Jan 25

Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.6 out of 10, (275 reviews)
cleanliness Convenient Cairo hotel offers comfortable stay with free breakfast and WiFi.
The price is $71
$79 total
includes taxes & fees
Jan 31 - Feb 1

Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.0 out of 10, Very Good, (43 reviews)
cleanliness Welcoming roadside retreat with quick access to I-55 and daily breakfast service.
The price is $56
$64 total
includes taxes & fees
Jan 22 - Jan 23

Travel Inn
Travel InnMarston
6.0 out of 10, (117 reviews)
The price is $45
$51 total
includes taxes & fees
Jan 22 - Jan 23

Reelfoot Lake Inn
Reelfoot Lake InnTiptonville
7.2 out of 10, Good, (465 reviews)
The price is $52
$65 total
includes taxes & fees
Jan 30 - Jan 31

Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of AmericaUnion City
9.2 out of 10, Wonderful, (332 reviews)
cleanliness Wake up to historic adventure at this convenient Union City hotel near Discovery Park.
The price is $80
$95 total
includes taxes & fees
Jan 29 - Jan 30

Holiday Inn Express & Suites Union City by IHG
Holiday Inn Express & Suites Union City by IHGUnion City
9.2 out of 10, Wonderful, (312 reviews)
cleanliness Take a morning dip in the indoor pool, steps from entertainment district.
The price is $100
$119 total
includes taxes & fees
Feb 21 - Feb 22
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in East Prairie
Pet friendly
Top landmarks in East Prairie
Learn more about East Prairie
East Prairie is well-known for its attractions such as Big Oak Tree State Park and Mississippi River.

Check out reviews of East Prairie hotels guests love

Best Western Plus Sikeston
10/10 Excellent




































































