Hotels in East Prairie

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Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (389)
The price is $65
$72 total
includes taxes & fees
Jul 23 - Jul 24
Quality Inn Charleston - Sikeston

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
6.6 out of 10, (572)
The price is $65
$72 total
includes taxes & fees
Jul 17 - Jul 18
Super 8 by Wyndham Charleston/Sikeston East MO

Eagle Inn Charleston

2.0 star property
6.8 out of 10, (100)
The price is $66
$73 total
includes taxes & fees
Jul 17 - Jul 18
Eagle Inn Charleston

Days Inn and Suites by Wyndham Sikeston

2.0 star property
7.2 out of 10, Good, (1001)
The price is $72
$82 total
includes taxes & fees
Jul 20 - Jul 21
Days Inn and Suites by Wyndham Sikeston

Best Western Plus Sikeston

2.5 star property
8.4 out of 10, Very Good, (1013)
The price is $88
$100 total
includes taxes & fees
Aug 10 - Aug 11
Best Western Plus Sikeston

Country Yard Inn and Suite

2.0 star property
7.2 out of 10, Good, (97)
The price is $65
$77 total
includes taxes & fees
Jul 17 - Jul 18
Country Yard Inn and Suite

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
8.4 out of 10, Very Good, (661)
The price is $70
$80 total
includes taxes & fees
Jul 19 - Jul 20
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Comfort Inn & Suites Sikeston I-55

2.5 star property
8.4 out of 10, Very Good, (268)
The price is $89
$102 total
includes taxes & fees
Aug 10 - Aug 11
Comfort Inn & Suites Sikeston I-55

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1001)
The price is $80
$92 total
includes taxes & fees
Jul 17 - Jul 18
Pear Tree Inn Sikeston

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1000)
The price is $102
$117 total
includes taxes & fees
Jul 27 - Jul 28
Drury Inn & Suites Sikeston, MO

Super 8 by Wyndham Sikeston/Miner Area

2.0 star property
6.6 out of 10, (543)
The price is $67
$76 total
includes taxes & fees
Jul 23 - Jul 24
Super 8 by Wyndham Sikeston/Miner Area

Hampton Inn Sikeston

2.5 star property
8.8 out of 10, Excellent, (361)
The price is $118
$134 total
includes taxes & fees
Jul 27 - Jul 28
Hampton Inn Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
8.6 out of 10, Excellent, (413)
The price is $108
$122 total
includes taxes & fees
Jul 20 - Jul 21
Holiday Inn Express & Suites Sikeston Southwest by IHG

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
10.0 out of 10, Exceptional, (14)
The price is $122
$138 total
includes taxes & fees
Jul 23 - Jul 24
Fairfield Inn & Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

3.0 star property
7.4 out of 10, Good, (3)
The price is $134
$152 total
includes taxes & fees
Jul 27 - Jul 28
TownePlace Suites by Marriott Sikeston

Quality Inn Cairo I-57

2.5 star property
6.6 out of 10, (261)
The price is $75
$83 total
includes taxes & fees
Aug 1 - Aug 2
Quality Inn Cairo I-57

Super 8 By Wyndham Marston

2.0 star property
8.0 out of 10, Very Good, (24)
The price is $96
$109 total
includes taxes & fees
Jul 18 - Jul 19
Super 8 By Wyndham Marston

Travel Inn

2.5 star property
5.8 out of 10, (105)
The price is $67
$77 total
includes taxes & fees
Jul 20 - Jul 21
Travel Inn

Reelfoot Lake Inn

2.0 star property
7.2 out of 10, Good, (443)
The price is $61
$164 total
includes taxes & fees
Aug 1 - Aug 2
Reelfoot Lake Inn

Sleep Inn at Discovery Park of America

2.5 star property
9.0 out of 10, Wonderful, (247)
The price is $89
$106 total
includes taxes & fees
Jul 27 - Jul 28
Sleep Inn at Discovery Park of America
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in East Prairie

Learn more about East Prairie

East Prairie is well-known for its attractions such as Big Oak Tree State Park and Mississippi River.

Check out reviews of East Prairie hotels guests love

Frequently asked questions

What hotels do travelers like in East Prairie?
Can I book a refundable hotel in East Prairie?
If you need the flexibility to change your travel plans to East Prairie, most hotels provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in East Prairie be like during my trip?
July and August are typically the warmest months in East Prairie when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. March and April are the months with the most rain.
Why should I book my East Prairie accommodation with Hotels.com?
There are lots of reasons to book your East Prairie trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.