Photo by Maria Athanasopoulou

Hotels in Mesenikolas

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Check prices for these dates

Tonight
Nov 2 - Nov 3
Tomorrow
Nov 3 - Nov 4
This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Where to stay in Mesenikolas?

A wooden deck with a table and chairs overlooking a lake and mountains.

1. Ktima Alonaki

Ktima Alonaki
3.0 star property
Lake Plastiras
10.0 out of 10, Exceptional, (6 reviews)
Tranquil retreat near Plastiras Dam offering free breakfast, WiFi, and parking. Unwind in the garden after exploring, then grab a bite at the café or sip drinks at the bar. A perfect base for lake adventures.
The price is $96
$111 total
includes taxes & fees
Nov 18 - Nov 19
Ktima Alonaki
A multi-story hotel with a classic architectural style, featuring balconies and arched windows.

2. Domotel Arni

Domotel Arni
4.0 star property
Karditsa
8.4 out of 10, Very good, (42 reviews)
Explore the heart of Karditsa from this welcoming hotel near Club of Photography and Lake Plastira. Enjoy a morning coffee at the café, unwind with evening drinks at the bar, and take advantage of free WiFi and parking during your stay.
The price is $79
$93 total
includes taxes & fees
Nov 5 - Nov 6
Domotel Arni
A poolside area with stone buildings, outdoor seating, and umbrellas.

3. Montanema Handmade Village

Montanema Handmade Village
4.0 star property
Mouzaki
9.4 out of 10, Exceptional, (34 reviews)
Escape to this handcrafted sanctuary in Mouzaki where local cuisine at Fournia restaurant complements dual swimming pools. The spa offers deep-tissue massages while apartments feature rainfall showers and plush bathrobes.
The price is $172
$199 total
includes taxes & fees
Nov 15 - Nov 16
Montanema Handmade Village
A stone building with a balcony overlooking a mountainous landscape.

4. Kanalia Suites

Kanalia Suites
Mouzaki
The price is $56
$64 total
includes taxes & fees
Nov 3 - Nov 4
Kanalia Suites
Breakfast area

5. Thessalikon Grand Hotel

Thessalikon Grand Hotel
Karditsa
8.8 out of 10, Excellent, (3 reviews)
Unwind at this business-friendly hotel near Karditsa's train station. Take a refreshing dip in the outdoor pool before grabbing drinks at the bar or snacks at the café. With Lake Plastira nearby and perks like free breakfast, WiFi, and parking, comfort awaits.
The price is $531
$603 total
includes taxes & fees
Nov 3 - Nov 4
Thessalikon Grand Hotel
A stone staircase leading to a balcony with a view of a mountainous landscape.

6. Ta livadia

Ta livadia
Argithea
9.0 out of 10, Wonderful, (2 reviews)
Tucked in the heart of Argithea, this charming guesthouse welcomes with a garden terrace and complimentary breakfast. Unwind with drinks at the bar or grab bites at the café and snack bar. Free parking adds convenience for countryside explorers.
The price is $71
$81 total
includes taxes & fees
Nov 3 - Nov 4
Ta livadia
A hotel room with a large bed, a red chair, a wall mural, and an air conditioning unit.

7. Gallery Art Hotel

Gallery Art Hotel
3.0 star property
Trikala
9.0 out of 10, Wonderful, (114 reviews)
Immerse yourself in this family-friendly art hotel near Ottoman Mosque Osman Shah. Enjoy authentic Greek dishes at Pinakas restaurant, relax at the lounge bar, and explore local attractions with the convenience of free WiFi and parking.
The price is $79
$91 total
includes taxes & fees
Nov 18 - Nov 19
Gallery Art Hotel
A swimming pool with a view of mountains and a sunset.

8. Ananti City Resort

Ananti City Resort
5.0 star property
Trikala
9.6 out of 10, Exceptional, (92 reviews)
The price is $150
$175 total
includes taxes & fees
Nov 8 - Nov 9
Ananti City Resort
A stone-walled balcony with a wooden chair and cushions, overlooking a lush green landscape.

9. Mikri Arktos

Mikri Arktos
3.0 star property
Pyli
9.6 out of 10, Exceptional, (11 reviews)
Escape to this cozy hotel near Pertouli Ski Center, where you'll enjoy free breakfast daily between 8:30 AM and 10:30 AM. Explore nearby hiking trails or visit the Arched Bridge of Portaikos River before returning to rooms with free WiFi and housekeeping service.
The price is $86
$100 total
includes taxes & fees
Nov 3 - Nov 4
Mikri Arktos
A courtyard with a stone floor, a metal fence, and a view of houses with red roofs in the background.

10. PIALEIA

PIALEIA
Pyli
The price is $64
$75 total
includes taxes & fees
Dec 3 - Dec 4
PIALEIA
A stone building with a central entrance, multiple balconies, and outdoor seating areas.

11. Giamandes Hotel

Giamandes Hotel
3.0 star property
Pyli
9.2 out of 10, Wonderful, (11 reviews)
Experience slope-side convenience at this mountain retreat featuring a full-service spa and hot tub for après-ski relaxation. Just minutes from Pertouli Ski Center and the Arched Bridge of Portaikos River, with free WiFi and parking for hassle-free adventures.
The price is $94
$109 total
includes taxes & fees
Nov 5 - Nov 6
Giamandes Hotel
A two-story building with a stone facade, balconies, and a stone fireplace.

12. Fretzato Traditional Guest House

Fretzato Traditional Guest House
Pyli
9.8 out of 10, Exceptional, (27 reviews)
The price is $81
$93 total
includes taxes & fees
Nov 3 - Nov 4
Fretzato Traditional Guest House
A modern building with large glass windows, stone walls, and outdoor seating.

13. Vintage Suites Trikala

Vintage Suites Trikala
Trikala
10.0 out of 10, Exceptional, (14 reviews)
Unwind at this inviting guesthouse with a seasonal outdoor pool and garden terrace. Just minutes from Trikala Castle and Clock Tower, enjoy complimentary breakfast, WiFi, and parking. A refreshing drink at the bar caps off days exploring nearby landmarks.
The price is $137
$156 total
includes taxes & fees
Nov 4 - Nov 5
Vintage Suites Trikala
A modern kitchen with a grey sofa, a dining area with two bar stools, and a refrigerator.

14. Icon Urban Living Trikala

Icon Urban Living Trikala
Trikala
10.0 out of 10, Exceptional, (1 review)
The price is $139
$158 total
includes taxes & fees
Nov 3 - Nov 4
Icon Urban Living Trikala
A modern hotel room with a large bed, white linens, and a wooden headboard.

15. Mini Suites Trikala

Mini Suites Trikala
Trikala
10.0 out of 10, Exceptional, (1 review)
The price is $97
$111 total
includes taxes & fees
Nov 3 - Nov 4
Mini Suites Trikala
A hotel room with a large bed, a wooden wardrobe, a small table with chairs, a sofa, a fireplace, and a window with curtains.

16. Elati Leisure -suites & apartments-

Elati Leisure -suites & apartments-
Pyli
Wake to enchanting mountain scenery at this cozy retreat near Pertouli Ski Center. Explore nearby hiking trails before unwinding in the garden terrace. With free WiFi and daily housekeeping, this guesthouse offers a serene escape just minutes from Arched Bridge of Portaikos River.
The price is $133
$151 total
includes taxes & fees
Nov 3 - Nov 4
Elati Leisure -suites & apartments-
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Go beyond your typical stay in Mesenikolas

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Pet friendly
Pet friendly
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Pool
Pool

Learn more about Mesenikolas

The region around Mesenikolas is home to attractions such as Lake Plastira and The Arch Bridge Waterfall of Paleokaria.

See all hotels in Mesenikolas
A snowy landscape with bare trees and a lake in the background.
Photo by Maria Athanasopoulou
Open Photo by Maria Athanasopoulou

Check out reviews of Mesenikolas hotels guests love

A wooden deck with a table and chairs overlooking a lake and mountains.
Ktima Alonaki

Ktima Alonaki

Ktima Alonaki
Lake Plastiras

10/10 Exceptional

Great breakfast buffet.
United States
George
Reviewed November 11, 2025
Ktima Alonaki

Frequently Asked Questions

What hotels do travelers recommend in Mesenikolas?

Guests like Thessalikon Grand Hotel, Domotel Arni and Ktima Alonaki.

Can I book a refundable hotel in Mesenikolas?

If you need the flexibility to change your plans to Mesenikolas, most properties provide refundable* rates you can book. You can find these properties by searching our site and using the "fully refundable" filter to narrow down the results.

What will the weather in Mesenikolas be like during my vacation?

The warmest months in Mesenikolas are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 44°F. The rainiest months are September and January.

Why should I book my Mesenikolas hotel through Hotels.com?

There are plenty of reasons to book your Mesenikolas travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.