Hotels in Saint Matthews

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Where to stay in Saint Matthews?

A gym with exercise equipment, a mirror, and a black box with an arrow.

A self-service food station with a variety of snacks, beverages, and ready-to-eat meals.

A pool table with balls, a sofa with cushions, a coffee machine, and a television mounted on the wall.

A hotel reception area with a central desk, a large window, and a seating area.

1. Tru by Hilton Orangeburg

Orangeburg

$110

$122 total

includes taxes & fees

Nov 8 - Nov 9

A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.

A hotel room with two beds, a seating area, and a large abstract painting on the wall.

A modern lobby with a wooden ceiling, a central seating area with a round table, and a bar with a variety of bottles.

An outdoor patio area with a fire pit, seating, and tables.

2. SpringHill Suites by Marriott Orangeburg

Orangeburg

$109

$121 total

includes taxes & fees

Oct 26 - Oct 27

A breakfast bar with pastries, fruits, and a vase with flowers.

A Travelodge motel with a parking lot and a signboard.

A hotel room with two beds, a nightstand, and two wall-mounted lamps.

A reception area with a dark-colored reception desk, a clock on the wall, and a doormat with "Travelodge" written on it.

3. Travelodge by Wyndham Orangeburg

Orangeburg

$62

$69 total

includes taxes & fees

Oct 21 - Oct 22

A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.

A lobby with a reception desk, a staircase, and seating area with orange chairs.

A modern kitchen with a wooden table and bench, blue cabinets, and a yellow pendant light fixture.

A modern indoor swimming pool with clear glass walls, sunlit lounge areas, and a view of greenery outside.

4. Spark by Hilton Orangeburg

Orangeburg

$98

$108 total

includes taxes & fees

Oct 26 - Oct 27

A lobby with a reception desk, a sofa, a coffee station, and a flag.

A modern restaurant with a counter, seating area, and a food display.

A Holiday Inn Express & Suites building with a clear entrance, a covered waiting area, and a landscaped garden.

A hotel room with a large bed, a desk, a chair, a nightstand, and a wall-mounted lamp.

5. Holiday Inn Express & Suites Orangeburg by IHG

Orangeburg

$118

$131 total

includes taxes & fees

Nov 8 - Nov 9

A reception desk with a flat-screen TV, a Dell computer, and a door.

A Red Roof Inn with two red leather armchairs and a small wooden table in front of a stone-patterned wall.

A hotel room with two beds, a desk, a chair, and a wall-mounted lamp.

A two-story building with a grey facade, large windows, and a covered entrance area.

6. Red Roof Inn Orangeburg

Orangeburg

$65

$72 total

includes taxes & fees

Oct 21 - Oct 22

A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

A reception area with a wooden reception desk, a welcome mat, a vending machine, and a clock on the wall.

A corner market with a refrigerator stocked with beverages and snacks.

A modern bar area with a stone fireplace, a flat-screen TV, and a coffee station.

7. Fairfield Inn by Marriott Orangeburg

Orangeburg

$101

$112 total

includes taxes & fees

Nov 1 - Nov 2

A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

A snack shop with a sign reading "Hampton Suite Shop" and a variety of snacks and drinks on display.

A gym with treadmills, a bench, and a ball.

A hotel room with a large bed, a desk with a flat-screen TV, a chair, a desk lamp, and a window with curtains.

8. Hampton Inn & Suites Orangeburg

Orangeburg

$135

$150 total

includes taxes & fees

Nov 8 - Nov 9

A spacious lobby with a sofa, chairs, a coffee table, and a staircase with a green leaf-patterned wall.

A reception area with a staircase, reception desk, and seating area with blue sofas.

A hotel room with a bed, bedside tables, a nightstand, a lamp, a wall-mounted phone, a painting, a window with curtains, and an air conditioning unit.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a modern design.

9. Sleep Inn Orangeburg

Orangeburg

$88

$98 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with a long counter, equipped with coffee makers, a kettle, and a microwave.

A multi-story hotel with a covered entrance, balconies, and a parking area.

A hotel room with a desk, a chair, a flat-screen TV, a refrigerator, a microwave, a lamp, and a large mirror.

A hotel room with a beige armchair, a black ottoman, a standing lamp, and an air conditioning unit.

10. Super 8 by Wyndham, Orangeburg

Orangeburg

$58

$65 total

includes taxes & fees

Nov 18 - Nov 19

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A spacious living area with a ceiling fan, a sofa, a coffee table, and a TV.

A pool area with lounge chairs and a building in the background.

A spacious dining area with a kitchen in the background, featuring a modern design with a ceiling fan, a clock, and a flat-screen TV mounted on the wall.

11. Quality Inn & Suites Orangeburg

Orangeburg

$60

$66 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with two beds, a desk, and a chair. There are wall-mounted lamps and a large window with curtains.

A Comfort Inn & Suites hotel with a brick facade, multiple windows, and a clear blue sky.

A reception area with a wooden reception desk, a wall-mounted clock, and a welcome mat.

A swimming pool with a 4ft depth marker, lounge chairs, and a covered seating area.

12. Comfort Inn & Suites Orangeburg

Orangeburg

$101

$112 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with a bed, a desk, a chair, a sofa, and a table.

A gym with cardio equipment, dumbbells, and a TV on a shelf.

A Baymont Inn & Suites reception desk with a sign indicating Orangeburg, South Carolina.

A breakfast corner with wooden tables and chairs, a coffee machine, and a sign indicating breakfast hours.

13. Baymont by Wyndham Orangeburg North

Orangeburg

$55

$61 total

includes taxes & fees

Nov 1 - Nov 2

A restaurant with round tables and chairs, a counter with a display case, and large windows.

A kitchen with wooden cabinets, a stainless steel range hood, and a black refrigerator.

A reception desk with a laptop, a patterned sofa, and a doormat with "SOUTHERN" visible.

A Southern Lodge building with a covered parking area, brick facade, and signage.

14. Southern Lodge 601

Orangeburg

$73

$81 total

includes taxes & fees

Oct 21 - Oct 22

A hotel room with a bed, a desk, a chair, and a hanging coat rack.

A modern kitchen with a granite countertop, a built-in microwave, a sink, and a mirror above the counter.

A spacious living area with a wooden floor, a ceiling fan, a flat-screen TV, and a large window with sheer curtains.

A reception area with a stone wall, wooden reception desk, and a seating area with a TV and plants.

15. Suburban Studios Orangeburg

Orangeburg

$59

$65 total

includes taxes & fees

Nov 18 - Nov 19

A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.

A Baymont by Wyndham hotel with a blue and yellow facade, a covered parking area, and a large parking lot.

A spacious dining area with multiple tables and chairs, large windows, and a patterned carpet.

A lobby with two leather armchairs, a marble-topped table, and a patterned carpet.

16. Baymont by Wyndham Santee

Santee

$80

$89 total

includes taxes & fees

Oct 21 - Oct 22

A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

A modern hotel lobby with a central reception desk, a children's play area, and a restaurant named "Top It Break."

A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.

A modern lobby with a blue sofa, teal chairs, and a wooden table.

17. Tru By Hilton Santee

Santee

$101

$112 total

includes taxes & fees

Nov 1 - Nov 2

A water park with a pool, slides, and umbrellas.

A reception desk with a wooden panel backdrop and a neon sign.

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

A cobblestone street lined with colorful buildings, a palm tree, and flowering trees.

18. Holiday Inn Santee by IHG

Santee

$110

$122 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a sofa, a bed with a red blanket, two bedside lamps, a small table, and a TV.

A motel with a row of single-story rooms, a covered front porch, and a parking lot.

A hotel room with a large bed, a desk, a chair, a TV, and a window with curtains.

A parking lot with multiple cars and a yellow truck.

19. Orangeburg Inn & Suites

Orangeburg

$54

$61 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor patio with a stone fire pit, seating, and a covered area with lights.

A modern reception area with a large digital display, a counter, and vending machines.

A modern kitchen with dark wood cabinets, a white countertop, and various kitchen appliances.

A modern hotel lobby with a curved sofa, dining area, and a kitchen in the background.

20. Springhill Suites by Marriott Columbia near Fort Jackson

Columbia

$100

$112 total

includes taxes & fees

Oct 25 - Oct 26

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Go beyond your typical stay in Saint Matthews

Pet friendly

Pool

Cottage

Family friendly

Learn more about Saint Matthews

The region around Saint Matthews is home to attractions such as Congaree National Park and Harry Hampton Visitor Center.

See all hotels in Saint Matthews

A swamp with tall trees and water reflecting the greenery.

Check out reviews of Saint Matthews hotels guests love

Cambria Hotel Columbia Downtown The Vista

10/10 Excellent

"I would recommend this hotel for a stay in Columbia. We had booked first with the Hilton and stayed only 1 night with was dirty ceiling was leaking we found this one and it was so clean and staff was really welcoming."

Country Inn & Suites by Radisson, Columbia, SC

10/10 Excellent

"The rooms are big, with a front room with refrigerator and microwave and back room for 1 bedrooms at a great price. Pool & jacuzzi were good too. Excellent price. A bit worn in places but clean, clean, clean overall."

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

10/10 Excellent

"When I travel through Columbia I always try to stay at this hotel because it is consistently excellent."

Tru By Hilton Columbia Downtown

10/10 Excellent

"Everything was perfect and exactly like how the photos showed"

Courtyard by Marriott Columbia Downtown at USC

10/10 Excellent

"The associate who welcomed us Sunday afternoon was very friendly, accommodating, and provided great information."

Fairfield Inn & Suites by Marriott Columbia Downtown

10/10 Excellent

"Great amenities and kind staff!"

The Lantern Hotel Columbia

10/10 Excellent

"It was amazing from check in to check out."

Hotel Trundle

10/10 Excellent

"Breakfast was good I love style of room and for me the little things the welcome drink and popcorn and slippers and robe"

Marriott Columbia

10/10 Excellent

"Clean room, helpful staff, accessible paid parking . I had a good experience and would return."

Frequently asked questions

What hotels do travelers like in Saint Matthews?

Guests like Tru by Hilton Orangeburg.

Can I book a refundable hotel in Saint Matthews?

If you want the flexibility to change your travel plans to Saint Matthews, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Saint Matthews be like during my trip?

July and August are typically the warmest months in Saint Matthews when the average temp is 79°F. January and February are the coldest months when the average temperature is 51°F. August and July are the months with the most rain.

Why should I book my Saint Matthews accommodation with Hotels.com?

There are lots of reasons to book your Saint Matthews trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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