Hotels in Saint Matthews

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This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Where to stay in Saint Matthews?

A modern interior with a dining area, seating, and a kitchen.

1. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,000 reviews)
The price is $110
$122 total
includes taxes & fees
Nov 15 - Nov 16
Tru by Hilton Orangeburg
A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.

2. SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (829 reviews)
Dive into comfort at this Orangeburg hotel with an indoor pool and free perks like WiFi, parking, and breakfast. Helpful staff welcome you near Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum & Planetarium.
The price is $109
$121 total
includes taxes & fees
Nov 4 - Nov 5
SpringHill Suites by Marriott Orangeburg
A breakfast bar with pastries, fruits, and a vase with flowers.

3. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very good, (1,003 reviews)
Experience comfort at this Orangeburg motel with clean rooms and helpful 24-hour staff. Located near Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum & Planetarium, enjoy convenient free WiFi and parking throughout your stay.
The price is $69
$77 total
includes taxes & fees
Nov 1 - Nov 2
Travelodge by Wyndham Orangeburg
A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

4. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very good, (846 reviews)
Near Smith-Hammond-Middleton Memorial Center, this business-friendly hotel offers free breakfast, WiFi, and parking. Take a refreshing dip in the seasonal outdoor pool or visit the fitness center. Clean rooms and helpful staff create a welcoming atmosphere.
The price is $101
$112 total
includes taxes & fees
Nov 2 - Nov 3
Fairfield Inn by Marriott Orangeburg
A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.

5. Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
2.5 star property
Orangeburg
8.0 out of 10, Very good, (1,002 reviews)
Wake up refreshed at this Orangeburg hotel where a seasonal outdoor pool awaits your morning swim. The fitness center keeps your routine on track while free breakfast, WiFi, and parking add value. Located near Smith-Hammond-Middleton Memorial Center, with staff ready to assist.
The price is $89
$99 total
includes taxes & fees
Nov 29 - Nov 30
Spark by Hilton Orangeburg
A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

6. Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (860 reviews)
Just minutes from Smith-Hammond-Middleton Memorial Center, this hotel offers a refreshing outdoor pool and morning workouts in the fitness center. Guests rave about the helpful staff and clean rooms, while free WiFi and parking enhance your stay.
The price is $127
$141 total
includes taxes & fees
Nov 25 - Nov 26
Hampton Inn & Suites Orangeburg
A spacious lobby with a sofa, chairs, a coffee table, and a staircase with a green leaf-patterned wall.

7. Sleep Inn Orangeburg

Sleep Inn Orangeburg
2.5 star property
Orangeburg
7.6 out of 10, Good, (475 reviews)
Feel refreshed at this welcoming Orangeburg hotel with a seasonal outdoor pool and daily continental breakfast from 6-9 AM. Free WiFi and parking add value, while nearby attractions include the Smith-Hammond-Middleton Memorial Center.
The price is $88
$98 total
includes taxes & fees
Nov 27 - Nov 28
Sleep Inn Orangeburg
A Holiday Inn Express & Suites hotel with a prominent sign, a central entrance, and a symmetrical facade.

8. Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (867 reviews)
Relax in the seasonal outdoor pool after a workout in the 24-hour fitness center. This Orangeburg hotel offers clean rooms, free breakfast, WiFi, and parking near Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum & Planetarium.
The price is $118
$131 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Express & Suites Orangeburg by IHG
A hotel room with two beds, a desk, a chair, and a wall-mounted lamp.

9. Red Roof Inn Orangeburg

Red Roof Inn Orangeburg
2.0 star property
Orangeburg
5.8 out of 10, (749 reviews)
This hotel offers the perfect quiet atmosphere for a good night's sleep near Smith-Hammond-Middleton Memorial Center. Convenient free perks include on-the-go breakfast, WiFi, and parking, making it ideal for travelers visiting Orangeburg attractions.
The price is $57
$63 total
includes taxes & fees
Nov 10 - Nov 11
Red Roof Inn Orangeburg
A modern kitchen with a long counter, equipped with coffee makers, a kettle, and a microwave.

10. Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg
2.0 star property
Orangeburg
7.0 out of 10, Good, (1,000 reviews)
Wake up refreshed at this welcoming Orangeburg motel offering free WiFi and on-the-go breakfast each morning. Near Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum, this spot provides free parking and earns praise for its attentive staff.
The price is $59
$65 total
includes taxes & fees
Nov 4 - Nov 5
Super 8 by Wyndham, Orangeburg
A hotel room with two beds, a desk, and a chair. There are wall-mounted lamps and a large window with curtains.

11. Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg
2.5 star property
Orangeburg
8.0 out of 10, Very good, (640 reviews)
This Orangeburg hotel has an indoor pool for year-round swimming and a fitness center for your workout needs. Enjoy complimentary breakfast, WiFi, and parking while being close to Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum & Planetarium.
The price is $101
$112 total
includes taxes & fees
Nov 15 - Nov 16
Comfort Inn & Suites Orangeburg
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

12. Quality Inn & Suites Orangeburg

Quality Inn & Suites Orangeburg
2.5 star property
Orangeburg
6.4 out of 10, Good, (710 reviews)
Wake up to continental breakfast at this Orangeburg hotel where free WiFi and parking add value to your stay. Located in a convenient spot for local dining, you'll find the Smith-Hammond-Middleton Memorial Center nearby. Business travelers appreciate the practical amenities and easy access.
The price is $60
$66 total
includes taxes & fees
Nov 22 - Nov 23
Quality Inn & Suites Orangeburg
A hotel room with a bed, a desk, a chair, a sofa, and a table.

13. Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North
2.5 star property
Orangeburg
5.8 out of 10, (1,000 reviews)
Minutes from Smith-Hammond-Middleton Memorial Center, this hotel offers a seasonal outdoor pool to cool off after exploring. Wake up to a complimentary buffet breakfast before heading to nearby stores and restaurants. Free WiFi and parking add value.
The price is $55
$61 total
includes taxes & fees
Nov 29 - Nov 30
Baymont by Wyndham Orangeburg North
A hotel room with a bed, a desk, a chair, and a hanging coat rack.

14. Suburban Studios Orangeburg

Suburban Studios Orangeburg
2.0 star property
Orangeburg
7.2 out of 10, Good, (31 reviews)
Wake up in a roomy studio with convenient kitchen facilities in Orangeburg. Free WiFi and parking make exploring easy, with Smith-Hammond-Middleton Memorial Center and I.P. Stanback Museum nearby. The 24-hour front desk ensures assistance whenever needed.
The price is $59
$65 total
includes taxes & fees
Nov 29 - Nov 30
Suburban Studios Orangeburg
A restaurant with round tables and chairs, a counter with a display case, and large windows.

15. Southern Lodge 601

Southern Lodge 601
Orangeburg
7.2 out of 10, Good, (25 reviews)
The price is $68
$75 total
includes taxes & fees
Nov 1 - Nov 2
Southern Lodge 601
A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

16. Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (1,003 reviews)
Bright, modern hotel near Santee National Golf Club with a refreshing indoor pool for year-round swimming. Guests love the complimentary breakfast, 24-hour fitness center, and helpful staff. Free WiFi and parking add convenience to your Santee visit.
The price is $101
$112 total
includes taxes & fees
Nov 8 - Nov 9
Tru By Hilton Santee
A hotel room with a sofa, a bed with a red blanket, two bedside lamps, a small table, and a TV.

17. Orangeburg Inn & Suites

Orangeburg Inn & Suites
2.0 star property
Orangeburg
6.2 out of 10, Good, (81 reviews)
This Orangeburg hotel offers free WiFi and parking with 24-hour front desk service. Visit nearby Edisto Memorial Gardens or South Carolina State College Historic District for local exploration during your stay.
The price is $54
$61 total
includes taxes & fees
Oct 30 - Oct 31
Orangeburg Inn & Suites
A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.

18. Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,498 reviews)
Escape to this quiet Santee hotel where comfortable beds await after exploring local golf clubs. Free perks include daily continental breakfast, WiFi, and parking. Guests praise the convenient location close to everything they need.
The price is $80
$89 total
includes taxes & fees
Nov 1 - Nov 2
Baymont by Wyndham Santee
A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

19. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,000 reviews)
The price is $123
$137 total
includes taxes & fees
Nov 25 - Nov 26
Hampton Inn Santee-I-95
A modern kitchen with dark cabinets, a granite countertop, a ceiling fan, a flat-screen TV, and a breakfast bar with pastries.

20. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
5.8 out of 10, (612 reviews)
Wake up to free breakfast at this convenient Santee hotel with 7 dining options and a seasonal outdoor pool. After exploring nearby Santee Cooper Country Club, unwind at the bar. Clean rooms, helpful staff, and free WiFi and parking enhance your stay.
The price is $54
$65 total
includes taxes & fees
Nov 19 - Nov 20
Quality Inn & Suites Santee I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Saint Matthews

The region around Saint Matthews is home to attractions such as Congaree National Park and Harry Hampton Visitor Center.

See all hotels in Saint Matthews
A swamp with tall trees and water reflecting the greenery.

Check out reviews of Saint Matthews hotels guests love

Hotel Trundle

Hotel Trundle

10/10 Excellent
"Na"
Melanie 3-night trip
Posted 4 hours ago
Hotel Trundle

Frequently asked questions

What hotels do travelers like in Saint Matthews?
Guests like Tru by Hilton Orangeburg.
Can I book a refundable hotel in Saint Matthews?
If you want the flexibility to change your travel plans to Saint Matthews, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Saint Matthews be like during my trip?
July and August are typically the warmest months in Saint Matthews when the average temp is 79Ā°F. January and February are the coldest months when the average temperature is 51Ā°F. August and July are the months with the most rain.
Why should I book my Saint Matthews accommodation with Hotels.com?
There are lots of reasons to book your Saint Matthews trip with us: our free cancellations on selected hotels gives you flexibility, and with One Keyā„¢, our rewards program, you will be able to earn and use OneKeyCashā„¢* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.