Hotels in Saint Matthews

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Where to stay in Saint Matthews?

A modern indoor pool area with a table and chairs, large windows, and a poolside lounge with sun loungers.

A modern kitchen with a wooden table and bench, blue cabinets, and a yellow pendant light fixture.

A hotel with a modern design, featuring a prominent 'Spark' sign, a well-maintained lawn, and a clear driveway.

A modern indoor swimming pool with clear glass walls, sunlit lounge areas, and a view of greenery outside.

1. Spark by Hilton Orangeburg

Orangeburg

$98

$108 total

includes taxes & fees

Oct 12 - Oct 13

A self-service kiosk with a beverage cooler, microwave, and various food items.

A modern interior with a dining area, seating arrangements, and a reception desk.

A modern hotel lobby with a reception desk, blue and gray seating, a TV screen, and unique pendant lighting.

A breakfast counter with a sign reading 'TOP IT BREAKFAST,' a coffee machine, a yogurt dispenser, and various food items.

2. Tru by Hilton Orangeburg

Orangeburg

$110

$122 total

includes taxes & fees

Nov 1 - Nov 2

A spacious dining area with multiple tables and chairs, a reception desk, and large windows providing natural light.

A hotel room with two beds, a seating area, and a large abstract painting on the wall.

A modern lobby with a wooden ceiling, a central seating area with a round table, and a bar with a variety of bottles.

An outdoor patio area with a fire pit, seating, and tables.

3. SpringHill Suites by Marriott Orangeburg

Orangeburg

$109

$121 total

includes taxes & fees

Oct 18 - Oct 19

A lobby with a reception desk, a sofa, a coffee station, and a flag.

A hotel room with a large bed, a desk, a chair, a nightstand, and a wall-mounted lamp.

A modern restaurant with a counter, seating area, and a food display.

A Holiday Inn Express & Suites building with a clear entrance, a covered waiting area, and a landscaped garden.

4. Holiday Inn Express & Suites Orangeburg by IHG

Orangeburg

$105

$117 total

includes taxes & fees

Nov 1 - Nov 2

A breakfast bar with pastries, fruits, and a vase with flowers.

A reception area with a dark-colored reception desk, a clock on the wall, and a doormat with "Travelodge" written on it.

A hotel room with two beds, a nightstand, and two wall-mounted lamps.

A Travelodge motel with a parking lot and a signboard.

5. Travelodge by Wyndham Orangeburg

Orangeburg

$60

$67 total

includes taxes & fees

Oct 11 - Oct 12

A stone fireplace with a television mounted above it, a small statue on the mantel, and a wooden cabinet to the left.

A modern bar area with a stone fireplace, a flat-screen TV, and a coffee station.

A workspace with two desks, each with a computer monitor, keyboard, and chair.

A corner market with a refrigerator stocked with beverages and snacks.

6. Fairfield Inn by Marriott Orangeburg

Orangeburg

$101

$112 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a sofa, chairs, a coffee table, and a staircase with a green leaf-patterned wall.

A reception area with a staircase, reception desk, and seating area with blue sofas.

A dining area with wooden tables and chairs, a large window with a view, a flat-screen TV, and a vending machine.

A hotel room with a bed, bedside tables, a nightstand, a lamp, a wall-mounted phone, a painting, a window with curtains, and an air conditioning unit.

7. Sleep Inn Orangeburg

Orangeburg

$83

$92 total

includes taxes & fees

Nov 1 - Nov 2

A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

A gym with treadmills, a bench, and a ball.

A snack shop with a sign reading "Hampton Suite Shop" and a variety of snacks and drinks on display.

A hotel room with a large bed, a desk with a flat-screen TV, a chair, a desk lamp, and a window with curtains.

8. Hampton Inn & Suites Orangeburg

Orangeburg

$135

$150 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with two beds, a desk, and a chair. There are wall-mounted lamps and a large window with curtains.

A restaurant with multiple tables and chairs, a wooden counter, and a painting on the wall.

A swimming pool with a 4ft depth marker, lounge chairs, and a covered seating area.

A Comfort Inn & Suites hotel with a brick facade, multiple windows, and a clear blue sky.

9. Comfort Inn & Suites Orangeburg

Orangeburg

$101

$112 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

A spacious dining area with a kitchen in the background, featuring a modern design with a ceiling fan, a clock, and a flat-screen TV mounted on the wall.

A spacious living area with a ceiling fan, a sofa, a coffee table, and a TV.

A spacious lobby with a central round table and chairs, a bar area, and a staircase leading to an upper level.

10. Quality Inn & Suites Orangeburg

Orangeburg

$48

$53 total

includes taxes & fees

Oct 18 - Oct 19

A modern kitchen with a long counter, equipped with coffee makers, a kettle, and a microwave.

A hotel room with a beige armchair, a black ottoman, a standing lamp, and an air conditioning unit.

A living room with a brown leather sofa, a matching armchair, a coffee table, and a striped rug.

A hotel room with a desk, a chair, a flat-screen TV, a refrigerator, a microwave, a lamp, and a large mirror.

11. Super 8 by Wyndham, Orangeburg

Orangeburg

$58

$65 total

includes taxes & fees

Nov 8 - Nov 9

A reception desk with a flat-screen TV, a Dell computer, and a door.

A hotel room with two beds, a desk, a chair, and a wall-mounted lamp.

A hotel reception area with a counter, coffee machines, and a refrigerator.

A Red Roof Inn with two red leather armchairs and a small wooden table in front of a stone-patterned wall.

12. Red Roof Inn Orangeburg

Orangeburg

$57

$63 total

includes taxes & fees

Oct 19 - Oct 20

A restaurant with round tables and chairs, a counter with a display case, and large windows.

A hotel room with two beds, a desk, and a mirror.

A Southern Lodge building with a covered parking area, brick facade, and signage.

A reception desk with a laptop, a patterned sofa, and a doormat with "SOUTHERN" visible.

13. Southern Lodge 601

Orangeburg

$75

$83 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a bed, a desk, a chair, a sofa, and a table.

A hotel with a swimming pool, outdoor seating, and a flagpole with an American flag.

A gym with cardio equipment, dumbbells, and a TV on a shelf.

14. Baymont by Wyndham Orangeburg North

Orangeburg

$55

$61 total

includes taxes & fees

Oct 15 - Oct 16

A hotel room with a bed, a desk, a chair, and a hanging coat rack.

A modern kitchen with a granite countertop, a built-in microwave, a sink, and a mirror above the counter.

A reception area with a stone wall, wooden reception desk, and a seating area with a TV and plants.

A spacious living area with a wooden floor, a ceiling fan, a flat-screen TV, and a large window with sheer curtains.

15. Suburban Studios Orangeburg

Orangeburg

$56

$62 total

includes taxes & fees

Oct 18 - Oct 19

A breakfast area with a self-service counter, refrigerated display, and a digital menu board.

A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.

A modern lobby with a blue sofa, teal chairs, and a wooden table.

A modern hotel lobby with a central reception desk, a children's play area, and a restaurant named "Top It Break."

16. Tru By Hilton Santee

Santee

$101

$112 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.

A spacious dining area with multiple tables and chairs, large windows, and a patterned carpet.

A lobby with two leather armchairs, a marble-topped table, and a patterned carpet.

A Baymont by Wyndham hotel with a blue and yellow facade, a covered parking area, and a large parking lot.

17. Baymont by Wyndham Santee

Santee

$80

$89 total

includes taxes & fees

Oct 11 - Oct 12

A hotel dining area with multiple tables and chairs, a large flat-screen TV, and a patterned wall design.

A hotel room with a bed, desk, chair, lamp, kitchenette, and a door.

A gym with treadmills, weight machines, and a wall of dumbbells.

A modern hotel with a swimming pool, outdoor seating, and a sign reading "Hampton Inn".

18. Hampton Inn Santee-I-95

Santee

$117

$130 total

includes taxes & fees

Nov 8 - Nov 9

A water park with a pool, slides, and umbrellas.

A cobblestone street lined with colorful buildings, a palm tree, and flowering trees.

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

A reception desk with a wooden panel backdrop and a neon sign.

19. Holiday Inn Santee by IHG

Santee

$104

$115 total

includes taxes & fees

Oct 18 - Oct 19

An outdoor patio with a stone fire pit, seating, and a covered area with lights.

A modern kitchen with dark wood cabinets, a white countertop, and various kitchen appliances.

A modern hotel lobby with a curved sofa, dining area, and a kitchen in the background.

A hotel room with a modern design, featuring a large bed, a desk, and a seating area with a tray table.

20. Springhill Suites by Marriott Columbia near Fort Jackson

Columbia

$97

$109 total

includes taxes & fees

Oct 25 - Oct 26

View all properties

Go beyond your typical stay in Saint Matthews

Pet friendly

Pool

Family friendly

Learn more about Saint Matthews

The region around Saint Matthews is home to attractions such as Congaree National Park and Harry Hampton Visitor Center.

See all hotels in Saint Matthews

A swamp with tall trees and water reflecting the greenery.

Check out reviews of Saint Matthews hotels guests love

Country Inn & Suites by Radisson, Columbia Airport, SC

10/10 Excellent

"I’ve stayed here multiple times on my visits to the area… this is my go to !! Highly recommend!!"

Hampton Inn & Suites Columbia/Southeast-Ft. Jackson

10/10 Excellent

"It was very nice to walk into a clean room at 4am in the morning after a seventeen hour drive."

Graduate by Hilton Columbia SC

10/10 Excellent

"Loved the Gamecock decor and location"

Tru By Hilton Columbia Downtown

10/10 Excellent

"Great new facility!"

Motel 6 West Columbia, SC - Airport

8/10 Good

"Fue buena opción para resolver estancia de último momento. Lo único que no me agradó fue un fuerte olor cada vez que entraba a la habitación, quizás algún detergente que dejó el olor. Otro detalle fue el TV, solo se pudo usar el primer día, ya que el resto de los días se perdió la conexión y no accesaba el servidor, lo que no permitía ver los canales."

Holiday Inn Express & Suites Columbia-Fort Jackson by IHG

10/10 Excellent

"Construction in the lot made I difficult to park my truck and trailer. I should’ve been informed of this construction at the time I called in for booking."

Frequently asked questions

What hotels do travelers like in Saint Matthews?

Guests like Tru by Hilton Orangeburg.

Can I book a refundable hotel in Saint Matthews?

If you want the flexibility to change your travel plans to Saint Matthews, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Saint Matthews be like during my trip?

July and August are typically the warmest months in Saint Matthews when the average temp is 79°F. January and February are the coldest months when the average temperature is 51°F. August and July are the months with the most rain.

Why should I book my Saint Matthews accommodation with Hotels.com?

There are lots of reasons to book your Saint Matthews trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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