Hotels in Saint Matthews

Free cancellation options if plans change

Earn rewards on every night you stay

Save more with Member Prices

Check prices for these dates

Next weekend
In two weeks

Where to stay in Saint Matthews?

Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very Good, (727 reviews)
  • cleanliness
    Swim into comfort at this Orangeburg hotel with fitness options and seasonal pool.
The price is $84
$93 total
includes taxes & fees
Mar 4 - Mar 5
Fairfield Inn by Marriott Orangeburg
Tru By Hilton Santee
Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (729 reviews)
  • cleanliness
    Experience a comfortable stay near Santee Cooper Country Club with top-rated service.
The price is $109
$121 total
includes taxes & fees
Mar 2 - Mar 3
Tru By Hilton Santee
Baymont by Wyndham Santee
Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,434 reviews)
  • cleanliness
    Relax in peaceful Santee with continental breakfast and helpful staff nearby.
The price is $80
$89 total
includes taxes & fees
Feb 22 - Feb 23
Baymont by Wyndham Santee
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
3.0 star property
Columbia
7.8 out of 10, Good, (1,008 reviews)
  • cleanliness
    Serene retreat near Fort Jackson with a seasonal pool for military families.
The price is $78
$89 total
includes taxes & fees
Feb 22 - Feb 23
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,005 reviews)
  • cleanliness
    Comfortable hotel in a tranquil setting, perfect for morning swims and golf outings.
The price is $125
$139 total
includes taxes & fees
Mar 1 - Mar 2
Fairfield Inn & Suites by Marriott Santee
Best Western Plus Santee Inn
Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,004 reviews)
The price is $112
$124 total
includes taxes & fees
Feb 22 - Feb 23
Best Western Plus Santee Inn
Courtyard by Marriott Columbia Cayce
Courtyard by Marriott Columbia Cayce
3.0 star property
Cayce
9.0 out of 10, Wonderful, (674 reviews)
  • cleanliness
    Wake up to Cayce's charm with refreshing dips in the outdoor pool.
The price is $110
$122 total
includes taxes & fees
Mar 1 - Mar 2
Courtyard by Marriott Columbia Cayce
Travelodge by Wyndham Orangeburg
Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very Good, (1,001 reviews)
  • cleanliness
    Modern Orangeburg stay with free WiFi and parking, near local attractions.
The price is $75
$83 total
includes taxes & fees
Feb 22 - Feb 23
Travelodge by Wyndham Orangeburg
Comfort Inn & Suites Orangeburg
Comfort Inn & Suites Orangeburg
2.5 star property
Orangeburg
8.0 out of 10, Very Good, (576 reviews)
  • cleanliness
    Comfort and convenience minutes away from Smith-Hammond-Middleton Memorial Center.
The price is $106
$118 total
includes taxes & fees
Mar 1 - Mar 2
Comfort Inn & Suites Orangeburg
Tru by Hilton Orangeburg
Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,006 reviews)
The price is $114
$127 total
includes taxes & fees
Mar 9 - Mar 10
Tru by Hilton Orangeburg
Quality Inn & Suites Orangeburg
Quality Inn & Suites Orangeburg
2.5 star property
Orangeburg
6.2 out of 10, (637 reviews)
  • cleanliness
    Affordable Orangeburg hotel with free amenities near dining and attractions.
The price is $63
$70 total
includes taxes & fees
Mar 1 - Mar 2
Quality Inn & Suites Orangeburg
Holiday Inn Express & Suites Orangeburg by IHG
Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (806 reviews)
  • cleanliness
    Stay steps from Columbia and enjoy free perks at this convenient Orangeburg hotel.
The price is $107
$119 total
includes taxes & fees
Mar 1 - Mar 2
Holiday Inn Express & Suites Orangeburg by IHG
Orangeburg Inn & Suites
Orangeburg Inn & Suites
2.0 star property
Orangeburg
6.2 out of 10, (59 reviews)
  • cleanliness
    Enjoy comfort and easy access to Orangeburg's local attractions at this welcoming inn.
The price is $54
$61 total
includes taxes & fees
Feb 22 - Feb 23
Orangeburg Inn & Suites
Spark by Hilton Orangeburg
Spark by Hilton Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (1,003 reviews)
  • cleanliness
    Central stay in Orangeburg with seasonal pool and complimentary breakfast.
The price is $95
$106 total
includes taxes & fees
Mar 1 - Mar 2
Spark by Hilton Orangeburg
SpringHill Suites by Marriott Orangeburg
SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (703 reviews)
  • cleanliness
    Relax by the indoor pool near I.P. Stanback Museum in this convenient Orangeburg stay.
The price is $114
$126 total
includes taxes & fees
Feb 27 - Feb 28
SpringHill Suites by Marriott Orangeburg
Suburban Studios Orangeburg
Suburban Studios Orangeburg
2.0 star property
Orangeburg
6.6 out of 10, (17 reviews)
  • cleanliness
    Visit Orangeburg for spacious comfort and convenient travel arrangements.
The price is $64
$71 total
includes taxes & fees
Mar 22 - Mar 23
Suburban Studios Orangeburg
Baymont by Wyndham Orangeburg North
Baymont by Wyndham Orangeburg North
2.5 star property
Orangeburg
6.0 out of 10, (1,000 reviews)
  • cleanliness
    Perfect spot in Orangeburg with seasonal pool, free breakfast, and parking.
The price is $57
$63 total
includes taxes & fees
Mar 1 - Mar 2
Baymont by Wyndham Orangeburg North
Econo Lodge Inn & Suites Cayce I-26 Airport
Econo Lodge Inn & Suites Cayce I-26 Airport
2.0 star property
Cayce
6.8 out of 10, (23 reviews)
The price is $62
$69 total
includes taxes & fees
Mar 22 - Mar 23
Econo Lodge Inn & Suites Cayce I-26 Airport
Comfort Inn & Suites Santee
Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very Good, (1,006 reviews)
  • cleanliness
    Relax in a serene hotel with a seasonal outdoor pool near Santee attractions.
The price is $107
$119 total
includes taxes & fees
Feb 22 - Feb 23
Comfort Inn & Suites Santee
Hampton Inn & Suites Orangeburg
Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (783 reviews)
  • cleanliness
    Escape to Orangeburg with a free breakfast, outdoor pool, and fitness center nearby.
The price is $130
$145 total
includes taxes & fees
Mar 8 - Mar 9
Hampton Inn & Suites Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Saint Matthews

The region around Saint Matthews is home to attractions such as Congaree National Park and Harry Hampton Visitor Center.

Moss Covered Cypress Trees Stand Tall in A Dark Marsh Of Congaree

Check out reviews of Saint Matthews hotels guests love

Frequently asked questions

What hotels do travelers like in Saint Matthews?
Can I book a refundable hotel in Saint Matthews?
If you want the flexibility to change your travel plans to Saint Matthews, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Saint Matthews be like during my trip?
July and August are typically the warmest months in Saint Matthews when the average temp is 79°F. January and February are the coldest months when the average temperature is 51°F. August and July are the months with the most rain.
Why should I book my Saint Matthews accommodation with Hotels.com?
There are lots of reasons to book your Saint Matthews trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.