Hotels in Wapello

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Check prices for these dates

Tonight
Nov 4 - Nov 5
Tomorrow
Nov 5 - Nov 6
This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

Where to stay in Wapello?

A modern living room with a large painting, a sofa, two armchairs, a coffee table, and a view of a lake through large windows.

1. The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
4.0 star property
Muscatine
9.6 out of 10, Exceptional, (311 reviews)
Wake up to spectacular Mississippi River views at this Muscatine gem. Just steps from Riverside Park and the Muscatine Art Center, the hotel features an indoor pool, fitness center, and Maxwell's restaurant serving American cuisine throughout the day.
The price is $149
$167 total
includes taxes & fees
Nov 20 - Nov 21
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
A spacious living room with a large sofa, two armchairs, a coffee table, and a fireplace.

2. AmericInn by Wyndham Mount Pleasant

AmericInn by Wyndham Mount Pleasant
3.0 star property
Mount Pleasant
8.6 out of 10, Excellent, (642 reviews)
Wake up to a delicious free breakfast at this convenient hotel with an indoor pool and fitness center. Located near Mt. Pleasant Station and local libraries, this quiet retreat offers free WiFi and parking with exceptionally helpful staff ready to assist.
The price is $76
$85 total
includes taxes & fees
Dec 3 - Dec 4
AmericInn by Wyndham Mount Pleasant
A modern lobby with a stone accent wall, comfortable seating, a reception desk, and a flat-screen TV.

3. Best Western Muscatine / Pearl City Hotel

Best Western Muscatine / Pearl City Hotel
2.5 star property
Muscatine
8.6 out of 10, Excellent, (561 reviews)
This riverside hotel offers an oasis of tranquility despite being in a busy area. Just 5 minutes from the Mississippi River, enjoy free breakfast before exploring nearby Muscatine Aquatic Center. The indoor pool provides year-round relaxation.
The price is $86
$96 total
includes taxes & fees
Nov 8 - Nov 9
Best Western Muscatine / Pearl City Hotel
A staircase with a metal railing, a display of books, and a door with an exit sign.

4. The Sage Hotel

The Sage Hotel
2.0 star property
Muscatine
6.8 out of 10, Good, (102 reviews)
Unwind at this welcoming hotel where free breakfast, WiFi, and parking enhance your stay. Located near Muscatine Aquatic Center and Geneva Golf and Country Club, this comfortable retreat offers convenience for exploring the area's popular spots.
The price is $60
$67 total
includes taxes & fees
Nov 5 - Nov 6
The Sage Hotel
A hotel room with a bed, a sofa, a chair, and a nightstand with lamps.

5. Quality Inn & Suites Mount Pleasant

Quality Inn & Suites Mount Pleasant
2.5 star property
Mount Pleasant
8.2 out of 10, Very good, (212 reviews)
Relax at this hotel with convenient train station access and complimentary amenities including daily buffet breakfast, WiFi and parking. The helpful staff receives consistent praise from travelers, while popular local attractions and libraries are just moments away.
The price is $66
$74 total
includes taxes & fees
Dec 1 - Dec 2
Quality Inn & Suites Mount Pleasant
A hotel room with three beds, a desk, and a television.

6. Comfort Inn Muscatine near Hwy 61

Comfort Inn Muscatine near Hwy 61
2.5 star property
Muscatine
7.8 out of 10, Good, (263 reviews)
Located near Highway 61, this welcoming hotel offers free WiFi, buffet breakfast, and parking. Take a refreshing swim in the indoor pool after exploring nearby Muscatine Aquatic Center and Geneva Golf and Country Club. Just 42 minutes from Quad City International Airport.
The price is $81
$90 total
includes taxes & fees
Nov 26 - Nov 27
Comfort Inn Muscatine near Hwy 61
A hotel room with two beds, a desk, a chair, and a large window.

7. Super 8 by Wyndham Mt Pleasant

Super 8 by Wyndham Mt Pleasant
2.0 star property
Mount Pleasant
8.2 out of 10, Very good, (878 reviews)
Escape to this tranquil hotel just a 3-minute drive from Mt. Pleasant Station. Wake up to complimentary breakfast, then explore nearby libraries. Enjoy free WiFi and parking while the attentive staff ensures a serene, clean retreat.
The price is $85
$95 total
includes taxes & fees
Nov 5 - Nov 6
Super 8 by Wyndham Mt Pleasant
Room

8. Strawberry Farm Bed & Breakfast

Strawberry Farm Bed & Breakfast
3.0 star property
Muscatine
9.4 out of 10, Exceptional, (32 reviews)
Wake up to cooked-to-order breakfast at this charming Muscatine retreat. Enjoy hiking trails along the Mississippi River, then unwind in the garden or terrace. Free WiFi and parking make exploration easy, with Geneva Golf and Discovery Park nearby.
The price is $162
$181 total
includes taxes & fees
Nov 5 - Nov 6
Strawberry Farm Bed & Breakfast
A hotel dining area with wooden furniture, a stone accent wall, and a view of the outdoors.

9. Hampton Inn Muscatine

Hampton Inn Muscatine
2.5 star property
Muscatine
8.4 out of 10, Very good, (506 reviews)
This modern hotel offers free daily buffet breakfast, WiFi, and parking. After exploring nearby attractions, recharge in the 24-hour fitness center. Conveniently located in Muscatine with easy access to Quad City International Airport, just 37 minutes away.
The price is $89
$100 total
includes taxes & fees
Nov 29 - Nov 30
Hampton Inn Muscatine
A large, two-story house with a porch, surrounded by lush green lawns and trees.

10. Evans Holly Grove Inn B&B

Evans Holly Grove Inn B&B
4.0 star property
Burlington
9.6 out of 10, Exceptional, (243 reviews)
The price is $140
$156 total
includes taxes & fees
Nov 8 - Nov 9
Evans Holly Grove Inn B&B
A patio area with Adirondack chairs and a central fire pit.

11. Hampton Inn & Suites Burlington

Hampton Inn & Suites Burlington
2.5 star property
Burlington
9.6 out of 10, Exceptional, (369 reviews)
The price is $110
$131 total
includes taxes & fees
Nov 29 - Nov 30
Hampton Inn & Suites Burlington
A well-lit indoor swimming pool with wooden walls and ceiling, surrounded by lounge chairs and umbrellas.

12. AmericInn by Wyndham West Burlington

AmericInn by Wyndham West Burlington
3.0 star property
West Burlington
7.0 out of 10, Good, (947 reviews)
Discover this family-friendly hotel with an inviting indoor pool near Westland Mall and Yohe Library. Enjoy complimentary breakfast, WiFi, and parking while exploring nearby hiking trails and water skiing opportunities. The helpful staff ensures a pleasant stay.
The price is $55
$62 total
includes taxes & fees
Nov 15 - Nov 16
AmericInn by Wyndham West Burlington
Room

13. Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn
2.5 star property
Mount Pleasant
8.2 out of 10, Very good, (904 reviews)
Unwind at this tranquil hotel set in an open field where the indoor pool and poolside bar offer relaxation. Near Mt. Pleasant Station, the clean rooms include microwaves and fridges for added convenience.
The price is $67
$75 total
includes taxes & fees
Dec 1 - Dec 2
Best Western Mt. Pleasant Inn
A hotel dining area with wooden chairs and tables, a coffee machine, and a buffet counter.

14. Quality Inn Burlington near Hwy 34

Quality Inn Burlington near Hwy 34
2.5 star property
Burlington
7.2 out of 10, Good, (456 reviews)
This Quality Inn serves up a free breakfast buffet and offers convenient access to FunCity and Catfish Bend Casino. With complimentary WiFi and parking, plus attentive staff praised by fellow travelers, your Burlington entertainment getaway is hassle-free.
The price is $64
$72 total
includes taxes & fees
Nov 15 - Nov 16
Quality Inn Burlington near Hwy 34
A hotel reception area with a modern design, including a reception desk, a beverage refrigerator, and a seating area with chairs.

15. Holiday Inn Express Hotel & Suites Burlington by IHG

Holiday Inn Express Hotel & Suites Burlington by IHG
2.5 star property
Burlington
8.6 out of 10, Excellent, (542 reviews)
Just minutes from Catfish Bend Casino and FunCity, this Burlington hotel offers a refreshing indoor pool and complimentary morning meals. Enjoy free WiFi and parking after exploring nearby attractions or working out in the fitness center.
The price is $125
$144 total
includes taxes & fees
Nov 20 - Nov 21
Holiday Inn Express Hotel & Suites Burlington by IHG
A modern living room with a leather sofa, a wooden coffee table, and a blue armchair.

16. Idyllic Biggsville Vacation Rental: 10 Mi to River

Idyllic Biggsville Vacation Rental: 10 Mi to River
3.0 star property
Biggsville
10.0 out of 10, Exceptional, (3 reviews)
Experience country charm in this cozy cottage with free parking and air conditioning. Located near the Horse and Buggy Museum and Dutton Lake, you're just a short drive from Burlington Station and Southeast Iowa Regional Airport.
The price is $150
$224 total
includes taxes & fees
Nov 5 - Nov 6
Idyllic Biggsville Vacation Rental: 10 Mi to River
A hotel room with a bed, a nightstand with a lamp, and two large framed pictures on the wall.

17. Super 8 by Wyndham Burlington

Super 8 by Wyndham Burlington
2.0 star property
Burlington
6.0 out of 10, Good, (815 reviews)
Enjoy free WiFi and on-the-go breakfast at this business-friendly hotel just 5 minutes from Mississippi River. With FunCity and Catfish Bend Casino nearby, plus Burlington Station within 4 minutes, you'll find comfort and accessibility in one spot.
The price is $57
$64 total
includes taxes & fees
Nov 13 - Nov 14
Super 8 by Wyndham Burlington
A modern lounge area with a stone fireplace, a blue sofa, and a small table.

18. Fairfield Inn & Suites by Marriott Burlington

Fairfield Inn & Suites by Marriott Burlington
3.0 star property
Burlington
8.4 out of 10, Very good, (324 reviews)
Wake to free breakfast at this business-friendly hotel before swimming in the indoor pool or heading to nearby Catfish Bend Casino. After exploring Burlington, return to your room, then grab a workout at the 24-hour fitness center.
The price is $118
$136 total
includes taxes & fees
Nov 29 - Nov 30
Fairfield Inn & Suites by Marriott Burlington
A hotel room with a bed, a desk, a chair, a lamp, a picture on the wall, and a door.

19. Midtown Motel Burlington Near Hwy 34

Midtown Motel Burlington Near Hwy 34
2.5 star property
Burlington
5.2 out of 10, (9 reviews)
The price is $57
$70 total
includes taxes & fees
Nov 14 - Nov 15
Midtown Motel Burlington Near Hwy 34
A neatly made bed with white linens, a wooden slatted headboard, a bedside table with a potted plant, and a wall-mounted lamp.

20. Hall Building

Hall Building
2.0 star property
Aledo
10.0 out of 10, Exceptional, (2 reviews)
Experience charming accommodations at this historic Hall Building in Aledo. Enjoy convenient amenities including complimentary WiFi and parking, plus on-site laundry facilities. Just a 42-minute drive from Quad City International Airport.
The price is $282
$299 total
includes taxes & fees
Nov 5 - Nov 6
Hall Building
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Go beyond your typical stay in Wapello

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Learn more about Wapello

The region around Wapello is home to attractions such as Mississippi River and Cairo Woods Wildlife Area.

See all hotels in Wapello
A river with a ship, surrounded by autumn foliage.

Check out reviews of Wapello hotels guests love

A modern living room with a large painting, a sofa, two armchairs, a coffee table, and a view of a lake through large windows.
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
Muscatine

10/10 Exceptional

Everything was excellent. So proud of my hometown to have such a nice place
United States
Laura
Reviewed May 17, 2022
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

Frequently Asked Questions

Can I book a refundable accommodation in Wapello?

If you want the flexibility to change your plans to Wapello, most properties offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Wapello be like during my trip?

July and August are typically the warmest months in Wapello when the average temp is 72°F. January and February are the coldest months when the average temperature is 30°F. June and May are the months with the most rain.

Why should I book my Wapello accommodation with Hotels.com?

There are lots of reasons to book your Wapello trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.