Hotels in Wapello

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Where to stay in Wapello?

A hotel room with three beds, a desk, and a television.

A restaurant with wooden flooring, red upholstered chairs, and a kitchen area with various appliances.

A reception area with a wooden counter, a reception desk, a digital kiosk, and a patterned rug.

A compact hotel room with a kitchenette, a blue sofa, a desk with a chair, a small refrigerator, and a microwave.

1. Comfort Inn Muscatine near Hwy 61

Muscatine

$72

$81 total

includes taxes & fees

Oct 2 - Oct 3

A modern lobby with a stone accent wall, comfortable seating, a reception desk, and a flat-screen TV.

An indoor swimming pool with a 'NO DIVING' sign, lounge chairs, and a pool area use sign.

A gym with treadmills, weight machines, and a mirrored wall.

A hotel room with two beds, a desk, a chair, and a television.

2. Best Western Muscatine / Pearl City Hotel

Muscatine

$94

$105 total

includes taxes & fees

Sep 13 - Sep 14

A large indoor swimming pool with a wooden ceiling and large windows.

A modern hotel room with a flat-screen TV, a wooden desk, a grey sofa, a patterned carpet, and a wooden-framed door leading to another room.

A reception area with a wooden reception desk, a stone pillar, and a staircase leading to an upper level.

A hotel room with two beds, a desk, a TV, and a large window.

3. AmericInn by Wyndham Muscatine

Muscatine

$89

$100 total

includes taxes & fees

Sep 20 - Sep 21

A modern living room with a large painting, a sofa, two armchairs, a coffee table, and a view of a lake through large windows.

A modern living room with a fireplace, large windows, and contemporary furniture.

A multi-story hotel with a prominent entrance and large windows.

A spacious banquet hall with round tables, chairs, and a large view of the outdoors.

4. The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

Muscatine

$169

$189 total

includes taxes & fees

Sep 25 - Sep 26

A hotel dining area with wooden furniture, a stone accent wall, and a view of the outdoors.

A hotel reception area with two computer workstations, a desk with a printer, and two office chairs.

A reception area with a stone counter, framed pictures, a welcome sign, and a carpeted floor.

A hotel pantry with shelves stocked with snacks and beverages.

5. Hampton Inn Muscatine

Muscatine

$93

$105 total

includes taxes & fees

Sep 20 - Sep 21

A staircase with a metal railing, a display of books, and a door with an exit sign.

A hotel room with two beds, a desk, a chair, a dresser, and a window with curtains.

A reception area with a stone counter, a red sofa, and a signboard.

A dining area with multiple wooden tables and chairs, a door with a sign, and a window with a view of the outside.

6. The Sage Hotel

Muscatine

$65

$73 total

includes taxes & fees

Oct 1 - Oct 2

A hotel room with two beds, a desk, a TV, a large window with curtains, and artwork on the walls.

A room with a brown leather sofa, a wooden coffee table with candles, a desk with a computer, and two windows with red curtains.

A hotel with a prominent 'Sofitel' sign, a brick facade, and a parking lot.

A breakfast area with a counter, coffee machines, and seating.

7. Super 8 by Wyndham Muscatine

Muscatine

$64

$71 total

includes taxes & fees

Oct 10 - Oct 11

A yellow building with a black entrance, a Coca-Cola sign, and a motel office sign.

A motel with two cars parked in front, a single-story building with a flat roof, and a utility pole in the background.

A cluttered room with boxes, a chair, and a desk.

8. Midtown Motel Burlington Near Hwy 34

Burlington

$75

$84 total

includes taxes & fees

Sep 13 - Sep 14

A patio area with Adirondack chairs and a central fire pit.

A modern hotel with a brick facade, large windows, and a covered entrance.

A spacious dining area with multiple tables and chairs, a television on a shelf, and a large chandelier.

A hotel room with a bed, a desk, a chair, and a TV.

9. Hampton Inn & Suites Burlington

Burlington

$123

$146 total

includes taxes & fees

Sep 17 - Sep 18

A hotel room with a bed, a sofa, a chair, and a nightstand with lamps.

A bathroom with a marble-tiled wall, a large bathtub, a wooden vanity with a television, and a patterned rug.

A hotel lobby with red seating, a checkered floor, and a large beverage dispenser.

A multi-story hotel with a covered entrance and a landscaped lawn.

10. Quality Inn & Suites Mount Pleasant

Mount Pleasant

$71

$80 total

includes taxes & fees

Oct 4 - Oct 5

A Holiday Inn Express hotel with a covered entrance, multiple windows, and a well-lit facade.

A breakfast station with a flat-top griddle, a coffee machine, and a sign indicating fresh pancakes are made in a minute.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A modern bathroom with a white sink, a mirror, and a coffee maker on a shelf.

11. Holiday Inn Express Hotel & Suites Burlington by IHG

Burlington

$133

$153 total

includes taxes & fees

Oct 9 - Oct 10

A hotel room with a bed, a sofa, a small table, a chair, a nightstand, and a painting on the wall.

A living room with a sofa, two armchairs, a coffee table with a plant, a lamp, and a TV on the wall.

A modern kitchen with a dining area, featuring a central island, built-in appliances, and a large window with blinds.

A modern reception area with a dark granite counter, light-colored walls, and a seating area with a sofa and chairs.

12. Best Western Mt. Pleasant Inn

Mount Pleasant

$78

$87 total

includes taxes & fees

Sep 20 - Sep 21

A spacious living room with a large sofa, two armchairs, a coffee table, and a fireplace.

A modern kitchen with a granite countertop, wooden chairs, and a large painting of a colorful horse.

An indoor swimming pool with wooden walls and a balcony.

A cozy living room with a grey sofa, two patterned armchairs, a wooden coffee table, and a brick accent wall.

13. AmericInn by Wyndham Mount Pleasant

Mount Pleasant

$84

$94 total

includes taxes & fees

Sep 20 - Sep 21

A large, two-story house with a porch, surrounded by lush green lawns and trees.

A hallway with a black wall, a white vase with branches, and two white robes hanging on a rack.

A bedroom with two beds, each with a headboard, a nightstand, and a wall-mounted lamp.

A black fireplace with a TV above it, a chandelier, and a door leading to another room.

14. Evans Holly Grove Inn B&B

Burlington

$140

$156 total

includes taxes & fees

Sep 12 - Sep 13

A water park with multiple slides and a pool area.

A modern lobby with a fireplace, patterned chairs, and a geometric coffee table.

An outdoor patio with striped sofas, a yellow ottoman, and a pool table.

A hotel room with a bed, desk, chair, and a TV on the wall.

15. Great River Hotel

Burlington

$116

$134 total

includes taxes & fees

Sep 20 - Sep 21

A modern lounge area with a stone fireplace, a blue sofa, and a small table.

An indoor swimming pool with clear water, tiled walls, and several lounge chairs along the side.

A Fairfield Inn & Suites Marriott hotel with a modern design, featuring a prominent entrance and a covered outdoor area.

A modern lobby with a stone wall, a reception desk, and seating areas.

16. Fairfield Inn & Suites by Marriott Burlington

Burlington

$135

$155 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with two beds, a desk, a chair, and a large window.

A bathroom with a bathtub, toilet, and sink.

A Super 8 motel with a brick facade, a covered entrance, and a parking lot with cars.

A small, clean room with a kitchenette, a coffee machine, a microwave, and a TV mounted on the wall. There are two tables and chairs, and a window providing natural light.

17. Super 8 by Wyndham Mt Pleasant

Mount Pleasant

$79

$88 total

includes taxes & fees

Sep 13 - Sep 14

A modern living room with a leather sofa, a wooden coffee table, and a blue armchair.

A building with a large garage door, a paved driveway, and a landscaped area with rocks and plants.

A bedroom with a large bed, a dresser, a TV, and a window with blinds.

A modern kitchen with blue cabinets, a white island, and a brick wall.

18. Idyllic Biggsville Vacation Rental: 10 Mi to River

Biggsville

$150

$224 total

includes taxes & fees

Sep 13 - Sep 14

A water park with multiple slides and inflatable tubes.

A casino interior with multiple gaming tables, a central bar area, and a distinctive circular ceiling design.

A modern bar area with a curved counter, overhead lighting, and multiple screens displaying content.

A spacious lobby with multiple seating areas, decorative lighting, and potted plants.

19. Fun City Resort Hotel

Burlington

$120

$142 total

includes taxes & fees

Sep 13 - Sep 14

A hotel dining area with wooden chairs and tables, a coffee machine, and a buffet counter.

A Quality Inn building with a brick facade, a clear blue sky, and an American flag.

A hotel reception area with a wooden reception desk, a red wall with the hotel name, and a sign about rewards.

A hotel room with two beds, a desk, a television, and a chair.

20. Quality Inn Burlington near Hwy 34

Burlington

$76

$86 total

includes taxes & fees

Sep 20 - Sep 21

View all properties

Go beyond your typical stay in Wapello

Pet friendly

Pool

Family friendly

Learn more about Wapello

The region around Wapello is home to attractions such as Mississippi River and Cairo Woods Wildlife Area.

See all hotels in Wapello

A tree-lined landscape with a river and fields.

Check out reviews of Wapello hotels guests love

Great River Hotel

10/10 Excellent

"It was all good"

Quality Inn & Suites Mount Pleasant

10/10 Excellent

"Looked like it was brand new. Room was spotless and had everything we needed. I will stay here next time I’m in town, that’s for sure."

AmericInn by Wyndham Muscatine

10/10 Excellent

"Everything was clean and as listed. Staff were friendly."

Fun City Resort Hotel

10/10 Excellent

"Friendly staff"

AmericInn by Wyndham West Burlington

8/10 Good

"We didn’t ask for maid service but 1 out of 5 days. When we did, she only picked up the trash and stuff on the bathroom floor and didn’t restock any of the towels or toilet paper. The staff was very helpful with getting extra wash cloths and hand towels."

Quality Inn Burlington near Hwy 34

10/10 Excellent

"It’s basic and modest accommodations, but great! Very clean, quiet and smells good. Room was in good shape. I suggest they pay better attention to plastic bags stuck on the back fence etc. Overall, a great deal plus breakfast. Pls Note: No elevator in two floor property, so if you have anyone with mobility needs, make sure you book the first floor!"

Hampton Inn & Suites Burlington

10/10 Excellent

"Very clean and nice."

The Sage Hotel

10/10 Excellent

"👍👍👍👍"

Hampton Inn Muscatine

8/10 Good

"A small fridge in the room would have been useful. Many hotels/motels still have them."

Frequently asked questions

Can I book a refundable accommodation in Wapello?

If you want the flexibility to change your plans to Wapello, most properties offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Wapello be like during my trip?

July and August are typically the warmest months in Wapello when the average temp is 72°F. January and February are the coldest months when the average temperature is 30°F. June and May are the months with the most rain.

Why should I book my Wapello accommodation with Hotels.com?

There are lots of reasons to book your Wapello trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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